Analysis of metagenomes

Lars Juhl Jensen

EMBL Heidelberg

the challenge

the sheer amount of data

what can we do with it?

function prediction

sequence homology

gene neighborhood

exploitation

bioremediation

statistical analyses

comparing environments

UndergroundMine Biofilm

SurfaceSea Water

Farm Soil Deep SeaWhale Skeleton

GC content

effective genome size

phylogenetic composition

functional fingerprints

visualization

metabolic reactions

saltmats are like onions …

… they have layers

QuickTime™ and a decompressor

are needed to see this picture.

Acknowledgments

EMBLJeroen Raes

Christian von MeringEoghan Harrington

Konrad FörstnerAmoolya SinghTakuji YamadaIvica Letunic

Peer Bork

JGISusannah TringePhil Hugenholtz

Eddy Rubin