analysis of dental images using artificial immune systems zhou ji 1, dipankar dasgupta 1, zhiling...

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Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1 , Dipankar Dasgupta 1 , Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis 2: Yinchuan Stomatological Hospital, China CEC 2006. Vancouver, BC, Canada. July 17, 20

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Page 1: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Analysis of Dental Images using Artificial Immune Systems

Zhou Ji1, Dipankar Dasgupta1, Zhiling Yang2 & Hongmei Teng1

1: The University of Memphis2: Yinchuan Stomatological Hospital, China

CEC 2006. Vancouver, BC, Canada. July 17, 2006.

Page 2: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

outline

Application background AIS method Data preprocessing Preliminary results

Page 3: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Application background

Occlusion: alignment of teeth/jaw Malocclusion

Abnormal occlusion Diagnosis using X-ray

Page 4: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

malocclusion

Different types: I (normal bite), II (overbite), and III (underbite)

Mild or severe (functional)

Page 5: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

lateral view skull X-ray

Normal case Example of malocclusion

Page 6: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

conventional diagnosis methodAngle’s classification: angle ANB (3 in the picture)

N

A

B

Page 7: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

AIS method

Negative selection algorithmsA detector set is generated from normal

samples and used to detect abnormal cases. One-class classification: classification

between two classes using samples from one class to train the systemanomaly detection

Page 8: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

V-detector

A new negative selection algorithmMaximized detection size of detectorsCoverage estimate

Page 9: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Data preprocessing method-feature extraction

Using brightness distribution instead of traditional feature extraction (identification of entities or anatomical parts)

Binarization at multiple thresholds Description of each binary image with four

real numbers

Page 10: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

remove artificial parts

Page 11: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

binarization using multiple thresholds

Page 12: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

choose thresholds

T0 = Vmax,

T1 = Vmax − (Vmax − Vmin)/n , ..., Tn-1 = Vmax − (n − 1)(Vmax − Vmin)/n ,

Thresholds are decided by the actual values of the image.

Page 13: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

decide reference point

Binarized at the highest threshold

Page 14: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

extract four featuresat each threshold (or for each binary image)

1. Horizontal displacementx = xwhite − x0,

(xwhite is the mean of x of white pixels)

1. Vertical displacementy = ywhite − y0,

(ywhite is the mean of y of white pixels)

1. Displacement distancer = mean of distances between white pixels to (x0, y0)

1. Area massA = total number of white pixel/width · height

Page 15: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Steps to represent an image as a real-valued vector

A grayscale image n binary images Each binary image 4 real values

1. Clean up 2. Binarization3. Calculate 4 features4. Normalization

Result: a grayscale image is represented by a 4n-dimensional vector over [0,1]4n

Page 16: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Preliminary experiment results

Page 17: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

compare with SVM

Page 18: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Using half of normal data to train

SVM result

V-detector result

Page 19: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Summary

V-detector shows some potentials. A novel feature extraction is proposed.

Key idea: general shapes instead of anatomical part Issues:

Other possible feature representations more normal data are desired.

Page 20: Analysis of Dental Images using Artificial Immune Systems Zhou Ji 1, Dipankar Dasgupta 1, Zhiling Yang 2 & Hongmei Teng 1 1: The University of Memphis

Thank you!

Questions?