tuberculosis in ireland: latest trends in surveillance …...interval between arrival in ireland...

Tuberculosis in Ireland:latest trends in surveillance dataHealth Protection Surveillance Centre

Last updated HPSCMarch 2019

TB notifications, rates & 3 year moving average

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TB notification rate by HSE area and year

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TB age-specific rates by year

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TB notifications and rate by geographic origin and year

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Interval between arrival in Ireland & notification as a TB case*:2011-2018

6*for foreign-born notifications with year of arrival in Ireland reported

Number of TB meningitis cases by year*

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TB meningitis cases and rates by age group: 1998-2018*

8*No cases of meningitis reported in 2016

Cumulative incidence rate of TB meningitis by HSE area:1998-2018

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HSE areaCumulative number of TBmeningitis notifications

Cumulative incidencerate per 100,000 95% CI

HSE-E 35 2.3 1.6 - 3.1HSE-M 0 0.0 0 - 0HSE-MW 8 2.2 0.7 - 3.8HSE-NE 12 3.0 1.3 - 4.8HSE-NW 4 1.7 0 - 3.3HSE-SE 7 1.5 0.4 - 2.6HSE-S 26 4.2 2.6 - 5.8HSE-W 8 1.9 0.6 - 3.3Ireland 100 2.4 1.9 - 2.8

Number of TB notifications & percentage culture positive by year

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Number and percentage of culture positive TB notificationsby species & year

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YearM. africanum M. bovis M. canettii M. tuberculosis M. tuberculosis

complexSpecies Unk

n % n % n % n % n % n %2009 1 0.3 8 2.3 0 0.0 328 96.2 0 0.0 4 1.22010 3 1.1 12 4.3 0 0.0 265 94.3 0 0.0 1 0.42011 0 0.0 6 2.2 0 0.0 263 95.6 6 2.2 0 0.02012 4 1.4 4 1.4 1 0.4 273 96.5 2 0.7 0 0.02013 4 1.4 6 2.1 0 0.0 270 96.1 1 0.4 0 0.02014 3 1.3 3 1.3 0 0.0 226 97.4 0 0.0 0 0.02015 0 0.0 5 2.5 0 0.0 190 96.4 1 0.5 1 0.52016 2 0.8 3 1.3 0 0.0 233 97.9 0 0.0 0 0.02017 0 0.0 4 1.8 0 0.0 210 96.8 3 1.4 0 0.02018 2 0.9 7 3.2 0 0.0 199 90.0 11 5.0 2 0.9

Percentage of culture positive TB notifications with DST*results available by year

12*Drug susceptibility testing

YearTotal

notifications New pulmonaryPrevious history of

TBPreviously treated for

TB2009 94.7 94.7 90.9 91.32010 97.9 98.8 100.0 100.02011 90.9 94.2 93.3 87.52012 97.9 97.4 100.0 100.02013 96.8 99.3 87.5 88.92014 99.6 100.0 100.0 100.02015 96.4 99.0 92.3 90.02016 98.3 99.2 100.0 100.02017 90.5 95.2 88.9 80.02018 85.5 85.3 83.3 100.0

Mean 2009-2018 94.9 96.3 93.6 93.8

TB notifications with resistance to any first line anti-TB drugby geographic origin and year

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Number of TB notifications with resistance to any first lineanti-TB drug by previous history of TB and year

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Number of MDR-TB, XDR-TB cases and % MDR/XDR TB caseby year

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Number & percentage of TB notifications with TB risk factorreported

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TB notifications by previous history of TB disease and year

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TB notifications by HIV status and year

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Number of TB notifications by treatment outcomes and year

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Treatment success by year

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85%Target

Number of MDR/XDR-TB notifications by treatment outcomeand year

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TB outbreak summary by year

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TB outbreaks by HSE area and year

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TB outbreaks by location and year

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Acknowledgements

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• The Health Protection Surveillance Centre would like tothank the staff of all the agencies who send data toenable TB surveillance in Ireland:

• Departments of Public Health• Irish Mycobacterial Reference Laboratory• Laboratories• Clinical staff

Prepared by:Sarah Jackson and Joan O’Donnell