tests that use dna from mother’s blood to

Manuela Amaya CossioMedicine student

3rd semesterMolecular biology

Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective and Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development

This technique needs the DNA amplification for making bigger the works zone it offers it the performance, duration,

specificity, detection capability and fidelity to the method

With all the applications the PCR has, the variations of the

method has to look for an specific topic and make it a better offer for getting the problem, they determine , increase amplify, generate

copies and impruve sensitivity for some DNA fragments

Tests That Use DNA

from Mother’s Blood to

Determine Sex of Fetus

Often Effective

Science Daily (Aug. 9, 2011)

Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective

Noninvasive prenatal determination of fetal sex could provide an important alternative to invasive cytogenetic determination, which is currently the gold standard for determining sex and single-gene disorders.

Using cell-free fetal DNA which describes the test's ability to detect Y chromosome sequences within maternal samples, as well as the clinical validity of the test, as indicated by its ability to correctly identify fetal sex.

Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective

Performance was high using maternal blood. DNA methodology and gestational age had the largest effects on test performance, with real-time quantitative polymerase chain reaction (RTQ-PCR) outperforming conventional PCR

Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective

Student observationlot of diseases have been diagnosticated

latter on life's person , just because there is not technology for doing it, so here is a tool could help people to do it, preventing those identity, sexual, psychological, physical and family problems.

Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring

Fetal Development

Science Daily (Aug. 9, 2011

 Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal DevelopmentUsing a previously developed

SNAP gene panel as proof of concept, investigators determined that 7 of the 21 genes assayed were expressed differently depending on fetal sex or gestational age.

Results were obtained from amniotic fluid supernatant samples from fetuses between 15 to 20 weeks of gestation, when standard amniotic fluid testing is performed.

According to the investigators, further studies using this gene panel approach could elucidate the complex immune pathways involved in the maternal-fetal relationship.

 Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development

Focused fetal gene expression analysis of target genes found in amniotic fluid using Standardized NanoArray PCR (SNAP) technology. And showed that This analysis could be used to monitor fetal development.

 Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development

Student observationA fetus development involve lot of

moments and each one needs the biggest attention because in any of them could occur a mistake, having the tool for follow this process can give parents the thrusts they need or the opportunity to give the baby a prudent treatment and prevent with it something worst for baby´s live

Medical utility

Medical utilityOver the time, technology

has help humans getting their dreams and make them true, today we can see it and enjoy it with things as live, born today has become on a very care posibility and baby´s health means the most important objective.

Medical utility Medicine takes those discoveries and put

them on parents hands giving them more options in case they need them just looking for something better.

In this case thechnique is use for an early diagnostic of sexual deseases, it can changes a complete life.

Medical utilityWith this method parents can know how is

going on theirs baby development even if he hasn´t born, the detection and early treatment of deformations, disseases, genetic desorders and any other problems can be diagnosticated with mother amniotic liquid.

BibliographyMARTINEZ S. Lina maría. Biología molecular. 6 ed. Medellín: UPB facultad de medicina. 2011. 113-126. p.· Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often EffectiveScience Daily (Aug. 9, 2011) de: http://www.sciencedaily.com/releases/2011/08/110809162000.htm · Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal DevelopmentScience Daily (Aug. 9, 2011) de: http://www.sciencedaily.com/releases/2011/08/110808083812.htm

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