supporting information for one-pot synthesis of silver

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Supporting information for

One-Pot synthesis of silver nanoparticle incorporated mesoporous silica granules

for hemorrhage control and antibacterial treatment

Wei Nie1†§

, Xinyi Dai1‡

, Dejian Li1ǁ

, David McCoul§, Gregory James Gillispie

§,

Yanzhong Zhang†, Baoqing Yu*

ǁ, Chuanglong He*

†

†College of Chemistry, Chemical Engineering and Biotechnology, Donghua

University, 2999 North Renmin Road, Shanghai 201620, China

‡Department of Plastic Surgery, Shanghai Jiaotong University affiliated First People's

Hospital, 650 Songjiang Road, Shanghai 201620, China

§Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine,

391 Technology Way NE, Winston-Salem, NC 27101, USA

ǁDepartment of Orthopedics, Shanghai Pudong Hospital, Fudan University Pudong

Medical Center, 2800 Gongwei Road, Shanghai 201301, China

*Corresponding author

Professor Chuanglong He

College of Chemistry, Chemical Engineering and Biotechnology, Donghua

University, 2999 North Renmin Road, Shanghai 201620, China.

Tel. /fax: +86 021 6779 2742 Email address: hcl@dhu.edu.cn (C.L He)

Professor Baoqing Yu

Department of Orthopedics, Shanghai Pudong Hospital, Fudan University Pudong

Medical Center, 2800 Gongwei Road, Huinan Town, Pudong New Area, Shanghai

201301, China.

Tel. /fax: +86 021 6803 5001 E-mail: doctorybq@163.com

6 pages, 5 figures

1. The SEM images of 10% and 20% AgNP-MSG

2. The AgNPs diameter distribution of AgNP-MSG

3. The XRD patterns of the 10% and 20% AgNP-MSG

4. Elements mapping and the elemental qualitative analysis of 5% AgNP-MSG

5. Masson's Trichrome staining of 5% AgNP-MSG in clot

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1. The SEM images of 10% and 20% AgNP-MSG

Figure S1. SEM images of 10% and 20% AgNP-MSG. The porous structure was

diminished with increasing amounts of added silver.

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2. The AgNPs diameter distribution of AgNP-MSG

Figure S2. The AgNPs diameter distribution of AgNP-MSG.(a) 1% AgNP-MSG (b)

2.5% AgNP-MSG (c) 5% AgNP-MSG

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3. The XRD patterns of the 10% and 20% AgNP-MSG

Figure S3. The XRD patterns of the 10% and 20% AgNP-MSG.

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4. Elements mapping and the elemental qualitative analysis of 5% AgNP-MSG

Figure S4. (a) O, (b) Si and (c) Ag elements mapping and (d) the elemental

qualitative analysis of 5% AgNP-MSG

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5. Masson's Trichrome staining of 5% AgNP-MSG in clot

Figure S5. Masson's Trichrome staining of 5% AgNP-MSG for a whole blood

absorption efficiency assay.