stage 0
Post on 15-Jan-2016
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Stage 0. Occipital. Frontal. Stage 1. trans-entorhinal cortex. trans-entorhinal cortex. Stage 2. Entorhinal cortex. Entorhinal cortex. likely asymptomatic. Stage 3. Hippocampus. Hippocampus. possible MCI. Stage 4. Temporal pole. Temporal pole (BA 38). probable MCI. Stage 5. - PowerPoint PPT Presentation
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Stage 0
Frontal
Occipital
Stage 1
trans-entorhinal cortex
trans-entorhinal cortex
Stage 2
Entorhinal cortex
likely asymptomatic
Entorhinal cortex
Stage 3
Hippocampus
possible MCI
Hippocampus
Stage 4
probable MCI
Temporal pole
Temporal pole (BA 38)
Stage 5
inferior temporal cortex
very probable MCI
Stage 6
Subtle but significant cognitive impairment
mid temporal cortex
mid temporal cortex
Stage 7
First stage of clinical Alzheimer’s disease
polymodal association cortex
polymodal association cortex
Stage 8
Broca area(BA 44)
Intermediate stage of AD
Stage 9
Moderate to severe AD
Unimodal areas
Unimodal areas
Stage 10
Last stage of AD
All neocortical areas are affected, and many subcortical areas as well
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