sowmya raghavan strand life

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Dr. Sowmya Raghavan

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Strand - an Introduction

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• Strand is a technology innovation company offering Scientific Intelligence solutions for use in discovery research

• Strand’s proprietary award-winning data-analysis and visualization software platform, AVADIS reflects 400 person years of continuous innovation evident. It powers several leading informatics products like GeneSpring, Sarchitect, Bioblox and WebChemistry.

• Strand offers “Virtual Lab” services - Computational biology/chemistry and informatics services to address pharma industry challenges

• Key IP and technology in AVADIS and Liver Toxicity Prediction

• $5M investment from Indian government to build and operate a genomic applications and informatics technologies labs

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Bioblox – A platform for Systems Modeling

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Bioblox enables biologists analyze their systems quantitatively

• GUI based model building

• Enables biologists test their hypotheses without employing “hardcore” math

• Enables collaboration and knowledge management within an enterprise

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Translate Biology into Mathematical ModelsCreate information-rich networks of

interactions

Model System

Model Network

Model System

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Design Experimentsfor disease evolution, clinical protocols, therapeutic regimens

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Parameter Set - Values

Input formats

Simulation Results

Homeostasis Disease

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Gain insights into model behaviorby hypothesis generation and testing

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Parameter Sensitivity

Compare Results from Multiple Hypotheses

Detect Events of Interest

Steady State Continuation

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Analyze and interpret resultswith a suite of dynamically linked visualizations

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Increase Biological understandingby simplifying networks visually

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Clone

Collapse

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Share Biological insights and datawith context specific annotations

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Manage Experiments; Store, Retrieve Results

Experiment Details

References

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Develop and analyze complex modelsmodularly enabling collaborations

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Analyze model components in isolation

Integrate Models Seamlessly

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Manage multiple projects Track model(s) evolution with versioning, user-access control

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Track multiple model builders, versions and use history

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Thank You

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