slideshare edition class 1 summer 2011 nsg 2500

NSG 2500: Pharmacology

Summer2011

Syllabus

Class Resources-Blackboard

Class Resources-The Point

Class Resources-EDGT

What is a Drug?

Drug Names

Trade Name

Generic name

Chemical name:methyl 7-((1R,2R)-3-hydroxy-2-((S,E)-4-hydroxy-4-methyloct-1-enyl)-5-oxocyclopentyl)heptanoate

Dosage Forms-Oral

TabletsCapsulesPills

Liquids

Suspensions

Dosage Forms-IM/SC

Dosage Forms-IV (parenteral)

Dosage Forms-Sublingual

Dosage Forms-Inhalation

Dosage Form-Transdermal

Dosage Form-Topical

Clinical Trials

Pregnancy Categories

A

B

C

D

X

The BEST (but there are not many!)

Controlled Substances

Controlled Substances

Narcotics, Amphetamines, Barbiturates, Many drugs used to

treat ADD/ADHD

Controlled Substances

Controlled Substances

Controlled Substances

Generic Drugs

Over the Counter Drugs

Over the Counter Drugs

Over the Counter Drugs

Over the Counter Drugs

Over the Counter Drugs

Over the Counter Drugs

Over the Counter Drugs

Sources of Drug Information

Drug Facts and Comparisons

Sources of Drug Information

PDR

Sources of Drug Information

United States Pharmacopeia, National Formulary

Sources of Drug Information

Nursing Drug Reference

Sources of Drug Information

Nursing Journals

Sources of Drug Information

Reliable Internet Sources

Sources of Drug Information

Reliable Internet Sources

Lexi-Comp through Levin Library or free for a month trial

Pharmacology Concepts

Pharmacology Drug therapy Pharmacodynamics

Drug to Body Pharmacokinetics

Absorption First Pass

DISTRIBUTION

Question:

What is an action of a drug?A. To increase enzymatic reactions in the bodyB. To alter a missing chemicalC. To depress or slow cellular activitiesD. To increase the effect of foreign substances

Pharmacology concepts

AbsorptionDistributionDrug BindingMetabolismExcretion

Protein Binding

Pharmacokinetics

Onset½ lifePeakDuration

Monitoring Drug Effects

Onset, Peak, Duration

Factors Influencing Drug Effects:Weight

Factors Influencing Drug Effects:Age

Factors Influencing Drug Effects: Physiology/Pathophysiology

Factors Influencing Drug Effects: Genetics

Factors Influencing Drug Effects

ImmunologicalPsychologicaEnvironmentalToleranceCumulative

Drug Effects

Therapeutic Index

Drug Interactions

Drug-Drug

Drug Interactions

Drug-Food

Drug Interactions

Drug-Herbal

Drug Interactions

Drug-Lab

Adverse Drug Reactions

PrimarySecondaryHypersensitivity

Allergic Reactions

Anaphylactic

Allergic Reactions

CytotoxicSerum SicknessDelayed Allergic

Drug Reactions

HIVES-URTICARIA

Drug Reactions

STOMATITIS

Drug Reactions

Superinfection

(ex: Thrush)

Drug Reactions

Bone Marrow Suppression

Drug Toxicity

LiverKidney

Adverse Effects

Altered glucose

metabolism

Adverse Effects

Electrolyte imbalance

Adverse Effects

Sensory effects

Adverse Effects

Neurological effects

Adverse Effects

Teratogenicity

Nursing Process & Patient Safety

Nursing Process

Rights of Drug Administration

StoragePreparationRecording

Promoting Drug Therapy

Preventing Medication Errors

Preventing Medication Errors

Drug information and the public

Federal Guidelines:Drug Advertising

MUST INCLUDE:Indication—Contraindications--Adverse effects--Precautions

Internet sources of drug information

Reliable or not????

Problems with OTC medications

Alternative Therapies

Off-label use of medications