proton therapy

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Welcome to our

presentation

Huynh Trong An

Ngo Trung

Nguyen Hoang Phi Yen

Tran Huu Loc

Outline

1. Definition

2. History

3. Mechanism

4. Applications

5. Others2

1. Definition

3

Proton therapy is a

type of particle

therapy which uses a

beam

of protons to irradiate

diseased tissue, most

often in the treatment

of cancer

2. History

4

1941, Robert R. Wilson

suggested that energetic

protons could be an

effective treatment

method.

1954-1957, the first treatment was

performed at Berkeley Radiation

Laboratory

1961, Harvard Cyclotron

Lab and Massachusetts

General Hospital pursue

proton therapy

By 2010, these facilities were joined by

an additional seven regional hospital-

based proton therapy centers in the

United States alone, and many more

worldwide.

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3. Mechanism

The New York Times and University of Florida Proton Therapy Institute

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Cyclotron and synchrotron accelerators

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Both the cyclotron and synchrotron are type of

particle accelerators

And both are used as a particle source

for high-energy collisions

Cyclotron Synchrotron

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But they each use different designs to accelerate particles.

However, they bot reply on two principles,

electricity and magnetism.

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Cyclotron

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Synchrotron

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Cyclotron Synchrotron

Constant magnetic field

and a constant frequency

electric field

Varying electric and

magnetic fields

A cylindrical or spherical

chamber.

A torus shaped tube

Its curve becomes larger A constant radius circle

250MeV 6.84TeV

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How can the proton therapy damage tumor?

O O

PROTON BEAM

O: :O+

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4. Applications

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The chief advantage of proton therapy

• Same tumor killing properties as X-rays

• Decreased dose to normal tissues, side effects and complications

• Treating tumors close to critical organs

• Increasing the safe dose delivered to tumors, cure rates

• Ability to re-treat tumors after recurrences

General example.

Brain tumors and inoperable brain lesions

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Tumors near the optic apparatus

Pediatric tumors (to reduce the

risk of secondary malignancies,

and to avoid the irradiation of

growth plates)

Comparison with other treatment options

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5. Others

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Cost

- For treatment

around £90,000 per person

$34,000 for eight weeks (medicare)

- For proton therapy machine:

$144 million to build

a cyclotron--220 tons

100-ton motorized gantry spins

Treatment centers

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5.3. Sum up

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