maddie\'s journey

Maddie’s Journey Through Maddie’s Journey Through Leukemia & Cord Blood Leukemia & Cord Blood

TransplantTransplant

10/2/200610/2/2006Diagnosis:Diagnosis:

Acute Acute LymphocytiLymphocytic Leukemia c Leukemia

Goal: Goal: Remission Remission in 28 Daysin 28 Days

TreatmenTreatment Plan t Plan

Includes Includes Chemo, Chemo, Steroids, Steroids,

and and AntibioticAntibiotic

ss

11/1/200611/1/2006One Month One Month

into into TreatmentTreatment

Primary Primary Induction Induction Failure Failure

Doctors Doctors Prepare a Prepare a

New New Treatment Treatment Plan while Plan while

Current Current Chemo Chemo Causes Causes

Hair LossHair Loss

11/7/200611/7/2006New New

Treatment Treatment Plan Plan

includes includes Inpatient Inpatient Chemo & Chemo &

Referral to Referral to U of M for U of M for

Bone Bone Marrow Marrow

TransplantTransplant

12/14/20012/14/20066

Remission Remission is Finally is Finally

Achieved!!Achieved!!!!

12/26/200612/26/2006In In

Remission Remission but but

Treatment Treatment Continues –Continues –

Second Second Round of Round of Inpatient Inpatient ChemoChemo

Winter 2006Winter 2006Friends Help Make the Hospital Friends Help Make the Hospital

Fun!Fun!

1/20/20071/20/2007Search of the Search of the National Bone National Bone

Marrow Marrow Registry Registry

Shows No Shows No Acceptable Acceptable

Marrow Marrow Matches but Matches but Several Cord Several Cord

Blood Blood Matches are Matches are

FoundFound

2/14/20072/14/2007Final Plans Final Plans are Set for are Set for Cord Blood Cord Blood Transplant Transplant at U of M, at U of M,

AlsoAlsoEnrolled in Enrolled in

Clinical Trial Clinical Trial Studying Studying

Double Cord Double Cord TransplantsTransplants

2/21/20072/21/2007Off to U of Off to U of M for Cord M for Cord

Blood Blood TransplantTransplant

2/22/2007 Napping after Placement of 2/22/2007 Napping after Placement of 22ndnd Central Line at CS Mott Children’s Central Line at CS Mott Children’s

HospitalHospital

Pre-Transplant Conditioning Pre-Transplant Conditioning Includes 5 Days of Chemo & 4 Includes 5 Days of Chemo & 4 Days of Total Body RadiationDays of Total Body Radiation

3/5/07 Double Cord Blood 3/5/07 Double Cord Blood TransplantTransplant

Pain From Mouth Pain From Mouth Sores Requires Sores Requires

Continuous Continuous MorphineMorphine

Failure to Take in Failure to Take in Enough Calories Enough Calories Orally Makes IV Orally Makes IV

Nutrition Nutrition NecessaryNecessary

Rising Blood Counts and Skin Rising Blood Counts and Skin Rash (GVHD) Signs of Rash (GVHD) Signs of

EngraftmentEngraftment

4/9/20074/9/2007Continuing Continuing to Battle to Battle

GVHD of the GVHD of the Skin & Gut Skin & Gut on Easteron Easter

Multiple Multiple Medications Medications to Control to Control

GVHD, GVHD, Starting to Starting to Feel BetterFeel Better

4/14/20074/14/2007First Post First Post

Transplant Transplant Bone Bone

Marrow Marrow Biopsy Biopsy

Shows No Shows No Leukemia Leukemia and 100% and 100%

Donor CellsDonor Cells

4/20/20074/20/2007After 2 Month After 2 Month

Stay Stay Discharged Discharged from Mott from Mott Children’s Children’s Hospital, Hospital, Moved to Moved to

Apartment in Apartment in Ann ArborAnn Arbor

Home Routine Includes Oral Home Routine Includes Oral Meds, IV Meds, & IV NutritionMeds, IV Meds, & IV Nutrition

5/21/2007 Home Again After 5/21/2007 Home Again After 3 Months in Ann Arbor3 Months in Ann Arbor

Summer Summer 20072007

Follow-up Follow-up AppointmentAppointments at U of M s at U of M

Cancer Cancer Center Every Center Every

2 Weeks 2 Weeks Throughout Throughout the Summerthe Summer

8/7/2007 Poor Appetite Leads to 8/7/2007 Poor Appetite Leads to Weight Loss and IV Nutrition is Once Weight Loss and IV Nutrition is Once

Again Required-Plans Made for Again Required-Plans Made for Surgical Placement of Feeding TubeSurgical Placement of Feeding Tube

9/21/2007 Surgery to Place Feeding 9/21/2007 Surgery to Place Feeding Tube in Stomach – Surgical Tube in Stomach – Surgical

Complication Leads to Perforated Complication Leads to Perforated Bowel And Emergency Surgery to Bowel And Emergency Surgery to

RepairRepair

10/31/200710/31/2007Healing from Healing from Surgery and Surgery and Thriving on Thriving on

Tube Tube FeedingsFeedings

12/200712/2007AppointmentAppointments to U of M s to U of M Becoming Becoming

Less Less Frequent, Frequent,

Reductions Reductions Made in Made in

Meds & Tube Meds & Tube FeedsFeeds

3/5/2008 3/5/2008 One Year One Year

Post Post Transplant:Transplant:Leukemia Leukemia Free and Free and

100% Donor 100% Donor CellsCells

4/29/20084/29/2008Issues Being Issues Being Monitored:Monitored:

GVHDGVHDEndocrine Endocrine

Issues Issues (Hypothyroidis(Hypothyroidis

m & m & Height/Weight)Height/Weight)

Survival into the Future!!Survival into the Future!!