human aging system diagram

HUMAN AGINDSYSTEM DIAGRAM

(HASD)RCAT – Research center

of advanced technologies

Imminst Conference-2010, 10-th October, 2010by Valerija Pride

http://www.sciencevsaging.org/

HistorySeptember 2008Medvedev D.

The goal

A systemic organization of accumulated knowledge

and determination of future directions to solve the problem of aging of

human organismФото: Corbis

A project of Russian Transhumanist Movement started in 2010Some of the projects it operates:

CAD software NanoInventor Human Aging System Diagram Telepresence robot “Teleput” “Path of upgrade” training center Industry report of the fight against aging field

RCAT – Research center of advanced technologies

Place

Gerontologists have their

puzzles too

Multidiscipline project HASD – is a multidiscipline project between gerontology and cognitive science

1. Геронтологи, молекулярные биологии иные специалисты

обладают знанием предмета

2. Методологи-когнитивщики обладают знанием о знании

как получить знания от специалистов как их оценить как организовать полученные знания

как сделать их доступными определить требуемую меру полноты

как получить новые знания и возможности

Specific

Three pillars in the basicof our results

1.

scie

nti

fic

meth

od

olo

gy

2.

meth

od

olo

gy o

f w

ork

ing

3.

vis

ual

meth

ods

Methodology

WHAT ?

1. Our diagram describes human aging. We ignore the aging of other species. At the same time we may extrapolate some data from laboratory animals to humans.

Comment: This is quite common in hot areas of science of human biology.

Scientific methodology

What ?2. We think it’s necessary to extract the cause-and-effect relationships between the aging processes (properly described), not all processes that happen in the organism. At the same time, constant processes, such as “digestion” are not included, but more specific processes, such as “decrease of gastric juice”, can be (if it’s related to aging).

Scientific HASD methodology

HOW ?3. So how do we describe aging? In the Human Aging System Diagram we have concentrated on describing the human aging processes. So the basic units of information are different processes connected to blocks.

So, HASD is not a diagram of metabolic pathways.

Scientific HASD methodology

HOW ?4. We describe aging starting at the top (natural primary causes) through cell disruption, decrease of function in tissues and organs and ending in pathologies and organism death (at the bottom). The entire process is one-directional (from top to bottom).

↓

Scientific HASD methodology

The initial aging-related HASD

HOW ?5. No feedback loops

Scientific methodology

Scientific methodology

6. The diagram should give sufficiently detailed elaboration of processes of ageing. The degree of elaboration is defined by internal logic of processes and the need to display sufficient details of aging process.

Additionally The diagram qualitatively describes, but

does not model the aging processes. In particular, the scheme is not equivalent to a computer model. Entering of numerical values into the diagram is supposed to happen at later stages of development of the project.

Other diagrams can be connected with HASD during the project.

Scientific methodology

Working methodology

Collecting knowledge (work with gerontologists and others)

expert interview using our methodology distributed work

Computer’s instruments CmapTools Get Satisfaction

Analysis TRIZ and other tools

HASD work methodology

CMAP Tools

GetSatisfaction

GetSatisfaction

Cognitive convenience and more

Visualization

Источник: www.math.yorku.ca/SCS/Gallery/

Visualization

“Report on the collapse of a bridge over the Rhone” in 1840 by visual engineer C. J. Minard:

Can you see why didthe bridge collapse?

Источник: VisualComplexity.com

Scientific evidence of effectiveness of modern supplements (for heart disease)

Visualization

HASD

HASD, var. № 50

meet

Top level diagram HASDFi

rst v

ersi

on

Second version

Our first experience in visualization

The authors1. The concept author & first director of the project:

Danila Medvedev, PhD, Research center for advanced technologies (RCAT), Moscow, Russia;

2. Artyuhov I.V., Institute of the Biology of Aging , Moscow, Russia;

3. Kaurov B.A., The Russian Roszdrav Research and Clinical Gerontological Center, Moscow, Russia;

4. Krementsova A.B., PhD, Institute of Biochemical Physics named after N.M. Emmanuel, Moscow, Russia;

5. Moskalev A.A., PhD, The Komi Institute of Biology of the Ural Region Research Center of the RF Academy of Sciences, Syktyvkar, The Komi Republic, Russia;

6. Mamayev V.B., PhD, Institute of Biochemical Physics named after N.M. Emmanuel, Moscow, Russia;

And…

6. Pasyukova E.H., PhD, Institute of Molecular Genetics, Moscow, Russia;

7. Sarvilina I.V., PhD, ООО «Medical Center «Novomeditcina», Rostov-on-Don, Russia;

8. Pride V., Research center for advanced technologies (RCAT), Moscow, Russia;

9. Yezhov M.D., Research center for advanced technologies (RCAT), Moscow, Russia;

10. Ilyin P.A., Research center for advanced technologies (RCAT), Moscow, Russia;

11. Maybe You ????;

Thank you for your attention!

Research center of advanced technologiesHuman Aging System Diagramwww.sciencevsaging.orgsva.org@gmail.com

Our Sponsor: Group «Rostok»www.grostock.ru , A. ChikunovRussian Transhumanism Movementwww.transhumanism-russia.ru

Valerija Pridepride@transhuman.ru +7 962 947-50-79