fig 14-2 fig 14-3 fig 14-4 table 14-2 fig 14-5

Fig 14-2

Fig 14-3

Fig 14-4

Table 14-2

Fig 14-5

Fig 14-6

Fig 14-7

Fig 14-8

Fig 14-9

Fig 14-10

Fig 14-11

Fig 14-12

Fig 14-13

Fig 14-14

Fig 14-15

More than 30 trinucleotide repeat expansion diseases have been identified

Such diseases often display “genetic anticipation.”

Fig 14-16

In the SOS response inE. coli, activated RecAcleaves the LexA repressor and leads toinduction of a numberof proteins, includingPol V

Fig 14-17

Fig 14-18

Fig 14-19

Fig 14-21

Note– this is not reallyrepair. It’s an exampleof “damage tolerance.” (Also, the detailed mechanism is not exactly as depicted here.)

Fig 14-23

Fig 14-24

Fig 14-26

Fig 14-27

Fig 14-29

fig 14-2 fig 14-3 fig 14-4 table 14-2 fig 14-5

pol v slide

expansion diseases

number of proteins

lexa repressor

sos response

example of damage tolerance

genetic anticipation

detailed mechanism

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