exercise 16: human reflex physiology. the reflex arc 1. reflex—rapid, predictable, and involuntary...
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Exercise 16: Human Reflex Physiology
The Reflex Arc
• 1. Reflex—rapid, predictable, and involuntary response to a stimulus
2. 5 Essential Components of the Reflex Arc
Figure 7.11a
Stimulus at distalend of neuron
Skin Spinal cord(in cross section)
Interneuron
Receptor
Effector
Sensory neuron
Motor neuron
Integrationcenter
(a)
The Reflex Arc
Figure 7.11a, step 1
Stimulus at distalend of neuron
Skin
Receptor
(a)
The Reflex Arc
Figure 7.11a, step 2
Stimulus at distalend of neuron
Skin
ReceptorSensory neuron
(a)
The Reflex Arc
Figure 7.11a, step 3
Stimulus at distalend of neuron
Skin Spinal cord(in cross section)
Interneuron
ReceptorSensory neuron
Integrationcenter
(a)
The Reflex Arc
Figure 7.11a, step 4
Stimulus at distalend of neuron
Skin Spinal cord(in cross section)
Interneuron
ReceptorSensory neuron
Motor neuron
Integrationcenter
(a)
The Reflex Arc
Figure 7.11a, step 5
Stimulus at distalend of neuron
Skin Spinal cord(in cross section)
Interneuron
Receptor
Effector
Sensory neuron
Motor neuron
Integrationcenter
(a)
Simple Reflex Arc
Figure 7.11b–c
Spinal cord
Sensory (afferent)neuron
Inter-neuron
Motor(efferent)neuron
Motor(efferent)neuron
Sensory receptors(stretch receptorsin the quadricepsmuscle)
Sensory (afferent)neuron
Sensory receptors(pain receptors inthe skin)
Effector(quadricepsmuscle ofthigh)
Effector(bicepsbrachiimuscle)
Synapse inventral horngray matter
(c)
(b)
3. Why test your reflexes?
•Reflexes determine the general health of the motor portion of the nervous system.
•Whenever reflexes are exaggerated, distorted, or absent, nervous system disorders are indicated.
•Reflex changes often occur before the pathological condition has become obvious
Simple Reflex Arc
Figure 7.11b, step 1
Spinal cord
Sensory receptors(stretch receptorsin the quadricepsmuscle)
(b)
Simple Reflex Arc
Figure 7.11b, step 2
Spinal cord
Sensory (afferent)neuron
Sensory receptors(stretch receptorsin the quadricepsmuscle)
(b)
Simple Reflex Arc
Figure 7.11b, step 3
Spinal cord
Sensory (afferent)neuron
Sensory receptors(stretch receptorsin the quadricepsmuscle)
Synapse inventral horngray matter
(b)
Simple Reflex Arc
Figure 7.11b, step 4
Spinal cord
Sensory (afferent)neuron
Motor(efferent)neuron
Sensory receptors(stretch receptorsin the quadricepsmuscle)
Synapse inventral horngray matter
(b)
Simple Reflex Arc
Figure 7.11b, step 5
Spinal cord
Sensory (afferent)neuron
Motor(efferent)neuron
Sensory receptors(stretch receptorsin the quadricepsmuscle)
Effector(quadricepsmuscle ofthigh)
Synapse inventral horngray matter
(b)
Simple Reflex Arc
Figure 7.11c, step 1
Spinal cord
Sensory receptors(pain receptors inthe skin)
(c)
Simple Reflex Arc
Figure 7.11c, step 2
Spinal cord
Sensory (afferent)neuron
Sensory receptors(pain receptors inthe skin)
(c)
Simple Reflex Arc
Figure 7.11c, step 3
Spinal cord
Inter-neuron
Sensory (afferent)neuron
Sensory receptors(pain receptors inthe skin)
(c)
Simple Reflex Arc
Figure 7.11c, step 4a
Spinal cord
Inter-neuron
Motor(efferent)neuron
Sensory (afferent)neuron
Sensory receptors(pain receptors inthe skin)
(c)
Simple Reflex Arc
Figure 7.11c, step 4b
Spinal cord
Inter-neuron
Motor(efferent)neuron
Sensory (afferent)neuron
Sensory receptors(pain receptors inthe skin)
Effector(bicepsbrachiimuscle)
(c)
Simple Reflex Arc
Figure 7.11b–c
Spinal cord
Sensory (afferent)neuron
Inter-neuron
Motor(efferent)neuron
Motor(efferent)neuron
Sensory receptors(stretch receptorsin the quadricepsmuscle)
Sensory (afferent)neuron
Sensory receptors(pain receptors inthe skin)
Effector(quadricepsmuscle ofthigh)
Effector(bicepsbrachiimuscle)
Synapse inventral horngray matter
(c)
(b)
Types of Reflexes and Regulation
• Somatic reflexes– Activation of skeletal muscles – Example: When you move your hand away from
a hot stove– A “stretch reflex” is a muscle contraction in
response to stretching within the muscle– “Superficial reflexes” are motor responses to
scraping of the skin.
4. Somatic Reflexes (Activation of skeletal muscles)
Achilles Reflex-Simple stretch reflexCord-mediated
Corneal Reflex
Patellar ReflexSimple stretch reflexCord-mediated
Plantar (Babinski) ReflexSuperficial cord reflex
5. Cord- Mediated Reflexes
• Muscle stretch (myotatic) reflexes are mediated purely at the spinal cord level, with monosynaptic connections between muscle spindle afferents and motor neurons to the muscle that was stretched.
• Examples: Achilles and plantar
5. Somatic reflex involving higher brain centers
• Example: pupillary light reflex
Patellar ReflexThe patellar reflex is an example of the monosynaptic reflex arc. There is no interneuron in the pathway.
Striking the patellar tendon with a tendon hammer just below the patella stretches the quadriceps muscles in the thigh. This stimulates stretch sensory receptors to trigger an afferent impulse in a sensory nerve fiber of the femoral nerve which synapses at the level of L4 in the spinal
From there, an motor neuron conducts an efferent impulse back to the quadriceps femoris muscle, triggering contraction. This contraction causes the leg to kick.
This reflex helps maintain posture and balance, allowing one to walk without consciously thinking about each step.
Superficial reflexes
• Superficial reflexes are motor responses to scraping of the skin.
• Plantar Reflex is a normal reflex that involves plantar flexion of the foot (toes move away from the shin, and curl down.)
• Babinski's reflex occurs when the big toe moves toward the top of the foot and the other toes fan out after the sole of the foot has been firmly stroked.
• This reflex, or sign, is normal in younger children, but abnormal after the age of 2.
Plantar Reflex
• Plantar Reflex: Flexion of the toes in response to stroking of the outer surface of the sole, from heel to little toe.
Plantar Reflex
Corneal Reflex
• Cranial Nerve V “trigeminal nerve”• Protect the eyeball from damage
Autonomic reflexes
• Autonomic reflexes– Smooth muscle regulation– Heart and blood pressure regulation– Regulation of glands– Digestive system regulationAn autonomic reflex is one that involves the response of an organ, such as the peristaltic contraction of the smooth muscle of the intestines, that is not controlled consciously
5. Example of Autonomic Reflex:Pupillary Light Reflex
• Receptor = retina of the eye• Afferent Fibers = in Cranial Nerve II,
“optic nerve”• Efferent impulses = carried by cranial nerve III
“ oculomoter nerve”• Effector = smooth muscles of the iris• Function =protects the retina from excessive
illumination, which is damaging to the photoreceptors
Pupillary Light Reflex
Autonomic Reflexes• May be spinal (e.g.,
urination and defecation) or modified by higher brain structures.
• The thalamus, hypothalamus and brain stem are in charge of multiple reflexes – HR, BP, breathing, eating, osmotic balance, temperature, vomiting, gagging, sneezing.
• All are polysynaptic.
9. Pupillary Response
• Ipsilateral: A reflex in which the response occurs on the side of the body that is stimulated.
• Contralateral: A reflex in which the response occurs on the opposite side of the body that is stimulated.
9. Test For Cranial Nerves II and III
• Normally, both pupils should constrict with light shone into either eye alone. If not working:
• Optic nerve damage?
• Oculomotor nerve damage?
10. Somatic vs Autonomic Reflexes
• Somatic Reflexes are all reflexes that stimulate skeletal muscles.
• Autonomic Reflexes stimulate smooth muscles, cardiac muscle, and glands of the body, and they regulate body functions such as digestion and blood pressure.
Types of Reflexes and Regulation
• Patellar, or knee-jerk, reflex is an example of a two-neuron reflex arc
Figure 7.11d
6. Reflex Arc of Patellar ReflexReceptors Afferent
NervesIntegration Center
Efferent Nerve Effector
Stretch receptors in quadriceps muscle
Afferent neuron
Spinal Cord Efferent neuron (Femoral Nerve)
Quadriceps muscle of the thigh
6. Reflex Arc of Achilles ReflexReceptors Afferent
NervesIntegration Center
Efferent Nerve Effector
Stretch receptors in Achilles Tendon
Afferent neuron
Spinal Cord Efferent neuron (Tibial Nerve, S1-S2)
Gastrocnemius muscle
7. Effect of Muscle Fatigue on Patellar Reflex
• The intensity of the response is less
Differences Between Somatic and Autonomic Nervous Systems
• Nerves– Somatic: one motor neuron– Autonomic: preganglionic and postganglionic
nerves• Effector organs– Somatic: skeletal muscle– Autonomic: smooth muscle, cardiac muscle, and
glands
PNS: Differences Between Somatic and Autonomic Nervous Systems
• Neurotransmitters– Somatic: always use acetylcholine– Autonomic: use acetylcholine, epinephrine, or
norepinephrine
Autonomic Nervous System
• Motor subdivision of the PNS– Consists only of motor nerves
• Also known as the involuntary nervous system– Regulates activities of cardiac and smooth muscles
and glands• Two subdivisions– Sympathetic division– Parasympathetic division
PNS: Comparison of Somatic and Autonomic Nervous Systems
Figure 7.27
Anatomy of the Sympathetic Division
• Originates from T1 through L2
• Ganglia are at the sympathetic trunk (near the spinal cord)
• Short pre-ganglionic neuron and long post-ganglionic neuron transmit impulse from CNS to the effector
• Norepinephrine and epinephrine are neurotransmitters to the effector organs
Figure 7.28
PNS: Anatomy of the Autonomic Nervous System
PNS: Sympathetic Pathways
Figure 7.29
Anatomy of the Parasympathetic Division
• Originates from the brain stem and S1 through S4
• Terminal ganglia are at the effector organs• Always uses acetylcholine as a
neurotransmitter
Autonomic Functioning
• Sympathetic—“fight or flight”– Response to unusual stimulus– Takes over to increase activities– Remember as the “E” division • Exercise, excitement, emergency, and embarrassment
Autonomic Functioning
• Parasympathetic—“housekeeping” activites– Conserves energy– Maintains daily necessary body functions– Remember as the “D” division• digestion, defecation, and diuresis
Table 7.3 (1 of 2)
Effects of the Sympathetic and Parasympathetic Divisions of the ANS
Effects of the Sympathetic and Parasympathetic Divisions of the ANS
Table 7.3 (2 of 2)
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