dr. anand srinivasan. collection of muscle fibers supported by connective tissue made of actin...
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Dr. ANAND SRINIVASAN
Collection of muscle fibers supported by connective tissue
Made of actin & myosin
Mesodermal origin
Special terms: Plasma membrane sarcolemma Cytoplasm sarcoplasm Smooth endoplasmic reticulum sarcoplasmic
reticulum Mitochondria sarcosomes
Three connective tissue layers :
Epimysium
Perimysium
Endomysium
Each muscle fiber is an elongated unbranched cylindrical cell.
Has many flat nuclei located beneath sarcolemma.
Has alternative dark A and light I bands with Z line intersecting I band.
Each muscle fiber made of myofibrils.
Non striated, elongated and spindle shaped
Found in the walls of hollow viscera e.g. GIT, blood vessels, uterine tube etc.,
Presence of cross striations & branching pattern
Nuclei in the center.
Presence of “intercalated discs”
Myasthenia Gravis Reduction in the number of Acetyl
Choline receptors.
Duchenne Muscular Dystrophy Mutation of “Dystrophin” protein located
in the sarcolemma
Chapter 6 – Microanatomy Workbook, RAKMHSU
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