disorders of calcium metabolism © ios/s nussey
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Disorders of calcium metabolism
©IOS/S Nussey
Box 5.2 - Control of serum calcium
Box 3.21 - Embryology of parathyroid glands
Normal parathyroid
Parathyroid adenoma
Hypercalcemia - Investigations
• Establish hypercalcemia is real; check renal function
• Measure serum PTH, 25-OH-vitamin D, PTHrp, T4, ACE as appropriate
• Radiological investigations– Basic - e.g. hands, KUB, CXR– Localization
Radiology of hyperparathyroidism
Sarcoidosis
Parathyroid - 99mTechnetium/201Thallium subtraction scan
Clinical Case 5.4 99mTechnetium bone scan
99mTc-sestaMIBI scan
(MIBI = methoxyisobutylisonitrile)
Box 5.28: Vitamin D deficiency
Box 5.28: Vitamin D deficiency
Clinical Case 5.7
Clinical Case 5.6
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