dengue fever ,dengue shock syndrome
Post on 23-Jan-2017
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Case presentation on
Dengue Fever,Dengue shock
syndrome
• Dengue fever also known as breakbone fever,
is a mosquito-borne topical disease caused by
the dengue virus
• Dengue fever, a benign syndrome caused
by several arthropod-borne viruses
Dengue fever
ETIOLOGY• Vector• Mosquito• Primarily Aedes Aegypti• Most female Ae. Aegypti
•Dengue virus▫Flavivirus: Single Stranded RNA virus▫Serotypes: DEN-1 to DEN-4
Incidence
▫2.5 billion people in over 100 endemic countries
▫50 million people infected annually with 500,000
cases of DHF and approx 20,000 deaths
Dengue Clinical Syndromes:
1.Undifferentiated fever;
2.Classic dengue fever;
3.Dengue hemorrhagic fever, or DHF; and
4.Dengue shock syndrome, or DSS.
Dengue Fever
Classical Dengue fever or Break bone fever is
an acute febrile viral disease frequently
presenting with headaches, bone or joint pain,
muscular pains,rash,and leucopenia
• Dengue hemorrhagic fever is a severe, often fatal, febrile disease caused by dengue viruses.
• It is characterized by capillary permeability, abnormalities of hemostasis, and, in severe cases, a protein-losing shock syndrome
4 Necessary Criteria:1.Fever, or recent history of acute fever 2.Hemorrhagic manifestations 3.Low platelet count (100,000/mm3 or less) 4.Objective evidence of “leaky capillaries:” • elevated hematocrit (20% or more over
baseline) • low albumin • pleural or other effusions
Dengue shock syndrome is the fourth clinical syndrome of dengue fever a sever form of Dengue hemorrhagic fever • 4 criteria for DHF
• Evidence of circulatory failure manifested indirectly by all of the following: • Rapid and weak pulse • Narrow pulse pressure (< 20 mm Hg) ORhypotension for age
• Cold, clammy skin and altered mental status
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Pathophysiology
Prevention
Prognosis
• Dengue fever < 1% mortality• Dengue hemorrhagic fever approx 2.5%
mortality• Primarily children
• Dengue shock up to 47% mortality
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