compare and contrast inorganic and organic molecules carbon dioxide (co2) glucose (c6h12o6) water...

Compare and Contrast inorganic and organic molecules

Carbon Dioxide (CO2)

Glucose (C6H12O6)

Water (H2O)

Methane (CH4)

4 Major Macromolecules -

•Proteins

•Carbohydrates

• Nucleic acids

• Lipids

These organic molecules comprise approximately 25% of all living

organisms !

Contrast the terms monomer and polymer

Monomers are the building blocks of polymers

Ex: Amino Acids -> Proteins (Polypeptides)

How do we build and breakdown macromolecules?

How do we build and breakdown macromolecules?

Monomers: monosaccharides

Monomers: monosaccharides

Covalently Joining Monosaccharides together…

How does variation in molecular building blocks provide cells with a wider range of functions?

How does variation in molecular building blocks provide cells with a wider range of functions?

Starches—major energy storage molecule in plants

Glycogen—major energy storage molecule in animals

Cellulose—major structural component of “plant-like” cell walls

**These polysaccharides are ALL comprised entirely of glucose monomers**

Images of Three Major Polysaccharides

How are lipids different from carbohydrates, even though they are composed of the same three elements?

Lipids are insoluble in water because of many nonpolar covalent bonds.

Widest Variation among molecules

Functions…

Figure 2.12 Saturated Fatty Acid (Part 1)

Figure 2.12 Unsaturated Fatty Acid (Part 2)

Explain the difference between a saturated fatty acid and an unsaturated fatty acid. Structure function relationship…

Saturated versus Unsaturated Fatty Acids…

THINK ABOUT IT:

At night, the cotton plant can avoid freezing by increasing the number of unsaturated fatty acids in its cell membranes…

How does this enhance its survival?

Figure 2.13 B Phospholipids

Nucleic Acids: Monomers - Nucleotides

3 components of a Nucleotide:

Polymers of Nucleic Acids: Examples!

The CENTRAL DOGMA OF BIOLOGY! DNA->RNA->Protein

A change in DNA sequence can affect all levels of organism function!

Amino Acids: The building blocks of proteins

20 different types in most biological systems

Same general structure with a variable “R” group

Covalently bonding Amino Acids to form a Protein:

The four levels of protein structure – Due to its extreme complexity

Primary structure: The sequence of amino acids in a polypeptide chain

Interactions: Peptide Bonds

Concept 3.2 Proteins Are Polymers with Important Structural andMetabolic Roles

Secondary structure – helices and pleated sheet structures seen in proteins

Interactions: H-bonds between H of one amino acid and O of nonadjacent a.a.s

Concept 3.2 Proteins Are Polymers with Important Structural andMetabolic Roles

Tertiary structure: Specific, unique 3D structure of a protein

Interactions: R-group interactions between each other and the environment

Ex: nonpolar attractions, + and – attractions, hydrophilic interactions with water

Figure 3.9 The Structure of a Protein

Quarternary Structure

Quaternary structure—Structure that results from multiple polypeptide chains interacting (ex: insulin, hemoglobin)

Digestive Enzymes!!

How can changes in molecular units of proteins result in a wider range of function?

Fetal versus Adult hemoglobin:

Antibody Diversity

Denaturation: Which level of protein structure would be disrupted first? Which level of protein structure would be the hardest to disrupt?

Changes in the environment resulting in changes in the 3D structure of a protein -> disrupts function

Tertiary disrupted first; Primary hardest to disrupt

THINK ABOUT IT:

How did this lesson demonstrate the relationship between structure and function of biological molecules?

Shape determines function is a MAJOR theme in biology. What determines the shape of these organic compounds?