cheminform abstract: synthesis and antimicrobial activity of heterocyclic ionone-like derivatives
Post on 06-Jun-2016
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2000 terpenes
terpenesU 0200
06 - 195Synthesis and Antimicrobial Activity of Heterocyclic Ionone-LikeDerivatives. — A number of new heterocyclic ionone-like derivatives such as(IV), (VI), (VII), and (X) (7 examples) is synthesized by one-pot cyclization ofcyclohexenylpentadienals (II) or (VIII) with appropriate bifunctional reagents.All the short heteroretinoids obtained possess remarkable antibacterial activity.Moreover, lipophilic compounds (IV) and (VI) exhibit excellent activity againstboth C. albicans and P. acnes. — (ANZALDI, MARIA; SOTTOFATTORI,ENZO; RIZZETTO, ROLANDO; GRANELLO DI CASALETO, BARBARA;BALBI, ALESSANDRO; Eur. J. Med. Chem. 34 (1999) 10, 837-842; Dip. Sci.Farm., Univ. Studi Genova, I-16132 Genova, Italy; EN)
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