cesium carbonate promoted n-alkylation of indoles
Post on 06-Jun-2016
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2005
Indole derivativesR 0140 Cesium Carbonate Promoted N-Alkylation of Indoles. — N-Alkylation of indoles,
even those containing electron-donating substituents, with alkyl halides as well as sty-rene oxide is smoothly achieved in the presence of the relatively weak base Cs2CO3 in dipolar aprotic solvents. — (FINK, D. M.; Synlett 2004, 13, 2394-2396; Dep. Med. Chem., Aventis Pharm., Bridgewater, NJ 08807, USA; Eng.) — Mischke
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