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Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

The Next Generation:A Research on Tap Celebrating Postdoctoral Research at BU

September 18, 2017

Research on Tap: The Next Generation

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Zhaoli (Joy) DaiPostdoctoral Fellow

Clinical Epidemiology Research & Training UnitMED

Research on Tap: The Next Generation

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Knee osteoarthritis (OA) Sleep quality and OA

Future studies

• Chronic pain and sleep deprivation are common in OA

• Sleep quality à ? Knee pain• Chronic widespread pain moderated

this relationship

• Intervention studies to identify mediating biomarkers in observed associations in knee OA

• Most common joint disorder• A leading cause of disability • Shares similar metabolic risk factors

as cardio-metabolic diseases

Dietary fiber and OA

• Fiber and health risks• Plausible mechanisms• Findings in two cohort studies• Featured in NY Times, Reuters, etc.

Lifestyle Factors for the Prevention of Knee Osteoarthritis

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Imane El MeouchePostdoctoral AssociateBiomedical Engineering

ENG

Research on Tap: The Next Generation

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Noise in gene expression Diversifying phenotypes and survival

Stochastic Gene Expression and Role in Antibiotic Resistance at the Single Cell Level

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Dries SelsPostdoctoral Fellow

PhysicsCAS

Research on Tap: The Next Generation

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

A: Static B: Moving C: Counter diabatic

Classical Mechanics Quantum Mechanics

Stat

istic

al p

hysi

csCan we exploit quantum phenomena to build better computers, sensors, … ?

Theo

ry

Mac

hine

Lea

rnin

g

Accelerating Quantum Computing

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Todd SponholtzPostdoctoral Fellow

Preventive Medicine & EpidemiologyMED

Research on Tap: The Next Generation

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Physical Environment

Social Environment

ObesityHypertensionDyslipidemia

Diabetes

CVDStroke

Individual Characteristics

DietPhysical Activity

SmokingSleepStress

Physical and social environments and cardiovascular disease risk

Physical and Social Environments and Cardiovascular Disease Risk

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Vural KaraPostdoctoral AssociateMechanical Engineering

ENG

Research on Tap: The Next Generation

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

E.coliinurinePre-Abx

~2hrs later

Susceptible

Resistant

•Bacteriaarecapturedinmicrofluidicchannelwitheitherpressureorelectricfield.

•Voltagefluctuationsandmeanresistancearemeasuredunderaconstantioniccurrentinurine.

(1)Applypressureorvoltagetoforcebacteriaintothecapturezone. (2)Measurevoltage.

Technology Results

• K.L. Ekinci, L. Li, C. Duan, V. Kara, D. Stearns-Kurosawa, US Appl. No. 15/669,069 - Filed on August 4, 2017• V. Kara, C. Duan, K. Gupta S. Kurosawa, D. Stearns-Kurosawa, K.L. Ekinci, submitted.• V. Kara and K.L. Ekinci founded “Fluctuate Diagnostics Corp.”

A Microfluidic Device for Rapid Antibiotic Susceptibility Testing

• Changesinmeanelectricalresistancereflectthegrowthofbacterialpopulation.

Non-motileS.epidermidis

t = 0 t = 2 hrs

Broth

Abx

Broth

Abx Loading 1hr 2hr 3hr 4hr0

5

10

15

20

% C

hang

e in

Res

ista

nce

(DR

/R)

Abx Broth

•Bacterialnanomechanical movementsmodulatevoltage,andthisreflectsbacterialviability.

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Abigail NoycePostdoctoral Fellow

Psychological & Brain SciencesCAS

Research on Tap: The Next Generation

sPCS

iPCS

tgPCS

cIFS

IPS/TOSIPS/TOS

Hig

h-level cognitio

n

Specialized frontal networks for visual & auditory cognition.

Noyce et al. 2017

Visual Auditory

55 2 2-log p

Michalka et al. 2015 Tobyne et al. 2017

Working MemoryAttentionResting-State Functional Connectivity

1

2

3

4

Spatial memory recruits vision areas

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Sarah HokansonDirector

Professional Development & Postdoctoral Affairs

Research on Tap: The Next Generation

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Boston University Slideshow Title Goes Here

Boston University Office of the Vice President and Associate Provost for Research

Thingsweareworkingon:

Professional Development & Postdoctoral Affairs

ProfessionalDevelopment• AGEPgrantfocusedoninclusivementoring• IUSEgrantfocusedonenhancingpostdocteachingskills• Bringabuddy– raffleprizesystemforevents• Individualdevelopmentplans

Community• Onboardingresources• Postdocassociationevents• Recipebook/wellnessopportunities

Benefits• Non-employeepostdochealthcare&MBTA