better science with sex and gender in mind shifting the paradigm in hiv research

Better Science with Sex and gender in mind

Shifting the paradigm in HIV researchXIX IAC Washington DC

23 July 2012 18:30 – 20:30

Dr. Shirin Heidari, IAS-ILFDr. Rowena Johnston, amfAR

amfAR

International Liaison Forum www.iasociety.org/ilf.aspx

IAS – Industry Liaison Forum (IAS–ILF)

Multi-stakeholder forum of the IAS with the mission to accelerate scientifically promising, ethical HIV research in resource-limited countries, with a particular focus on the role and responsibilities of industry as sponsors and supporters of research. IAS-ILF Strategic Plan 2012-2014

To accelerate HIV prevention and treatment research for women and children in resource-limited settings

http://www.iasociety.org/ilf.aspxF / T

Gender Editorial policy in 2010

Journal of the International AIDS Society

http://www.jiasociety.org

SEX Biological differences (mostly Binary)

XY XX

XXY

XXX

XYY

X0

Gender

Socially constructed notion of femininity and masculinity (continuum)

Gender role

Early phase Late phase Early phase Late phase Early phase Late phase1994-1997 2001-2004 2008-2011

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Men enrolledWomen enrolled

Prop

ortio

n of

men

/wom

en e

nrol

led

% of female and male participants in Cure clinical trials

Reporting of gender differences in articles from CT with ARVs

Research – Evidence - Knowledge

Knowledge Education

Ideas

Research design

Research results

PublicationPeer-

reviewedJournals

Resea

rch &

Clinical

gove

rnanc

e

Research Funding Body

“research must systematically

incorporate attention to sex and gender in

design, analysis, and interpretation of

findings” WHO 2009

Agenda

18:45-18:55 

What are the differences between women and men in the context of HIV? From transmission to treatment.By Dr. Linda-Gail Bekker, University of Cape Town

18:55-19:05 

Why gender analysis matters in science.By Prof. Londa Schiebinger, Stanford University 

19:05-19:15 

A practical guide to study design with sex and gender in mindBy Prof. Joy Johnson, Canadian Institutes of Health Research (CIHR)  

19:15-19:45

Moderated Q and A by co-chairs 

19:45-20:20 

Shaping the future of HIV science with gender in mind: Moderated discussion Moderated by Ms. Heidi Nass, IAS-ILF 

Panel Discussion

19:45-20:20 

Shaping the future of HIV science with gender in mind: Moderated discussion Moderator by Ms. Heidi Nass, IAS-ILF Panellists: Dr. Bryan Baugh, Janssen Dr. Gina Brown, Office of AIDS Research, NIH Dr. Pat Fast, IAVI (TBC) Dr. Rowena Johnston, amfAR Ms. Rahab Mwaniki, IAS-ILF Dr. Emma Veitch, PLOS medicine 

20:20-20:30 Closing Remarks