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AMERICAN SOCIETY FOR NEUROCHEMISTRY The Latest in Molecular and Cellular Neurobiology

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Page 1: AMERICAN SOCIETY FOR NEUROCHEMISTRY...©2008 American Society for Neurochemistry Terri Wood, Chair Regina Armstrong Stephen Back Scott Barnum Scott Brady Monica Carson American Society

AMERICAN SOCIETY FORNEUROCHEMISTRY

The Latest in Molecular and Cellular Neurobiology

Page 2: AMERICAN SOCIETY FOR NEUROCHEMISTRY...©2008 American Society for Neurochemistry Terri Wood, Chair Regina Armstrong Stephen Back Scott Barnum Scott Brady Monica Carson American Society

Officers

President - Monica Carson, Riverside, CA

Past President - Wendy Macklin, Cleveland, OH

Secretary - Steve Levison, Newark, NJ

Treasurer - Jean Merrill, Bridgewater, NJ

President Elect - Douglas Feinstein, Chicago, IL

Members of the Council

Alternate to the Council

Lucia Notterpek (2005—2009)

Susan McGuire (2007—2011)

Appointments

Intersociety Liaison - Mary McKenna

Parliamentarian - Cara-Lynne Schengrund

ASN Business Manager & Meeting Planner - Sheilah Jewart

Scientific Program Committee

San Antonio Host Committee

Babette Fuss (2007—2011)

Vittorio Gallo (2005—2009)

Tammy Kielian (2007—2011)

Eric Murphy (2005—2009)

Mathew Rasband (2007—2011)

Tom Seyfried (2005—2009)

David Shine (2005—2009)

Terri Wood (2005—2009)

Regina Armstrong (2005—2009)

Tika Benveniste (2007—2011)

Oscar Bizzozero (2007—2011)

Celia Campagnoni (2007—2011)

Ian Duncan

Marie Francois-Chesselet

Babette Fuss

Vittorio Gallo

Sandra Hewett

Tammy Kielian

Wendy Macklin

Ken McCarthy

Mary McKenna

Lucia Notterpek

Bruce Ransom

Matt Rasband

Cara-Lynne Schengrund

Ian Simpson

Harry Sontheimer

Wee Yong

Robert Yu

James Roberts, Chair

Randy Strong, Co-Chair

©2008 American Society for Neurochemistry

Terri Wood, Chair

Regina Armstrong

Stephen Back

Scott Barnum

Scott Brady

Monica Carson

American Society for NeurochemistryThe Latest in Molecular and Cellular Neurobiology

Page 3: AMERICAN SOCIETY FOR NEUROCHEMISTRY...©2008 American Society for Neurochemistry Terri Wood, Chair Regina Armstrong Stephen Back Scott Barnum Scott Brady Monica Carson American Society

Friday, February 293:00 pm – 7:00 pm ASN Registration Desk Open Los Rios Foyer

Saturday, March 17:00 am – 7:00 pm ASN Registration Desk Open Los Rios Foyer8:15 am – 5:00 pm Pre-Meeting Workshop Regency East

Glial-Neuronal Interactions: Cutting EdgeApproaches to Modeling CNS Function and Disease

8:30 am – 1:00 pm ISN Publications Board Meeting Frio Room12:30 pm – 5:00 pm ASN Council Meeting Pecos Room4:00 pm – 7:00 pm Job Postings Directors Room3:00 pm – 7:00 pm Internet Stations-Sponsored by Springer Directors Room4:30 pm – 6:30 pm Public Forum Chula Vista Room

Focus on Parkinson’s DiseaseCurrent and Emerging Concepts

6:30 pm – 8:00 pm ASN President’s Reception Regency Ballroom

Sunday, March 27:00 am – 7:00 pm ASN Registration Desk Open Los Rios Foyer7:00 am – 7:00 pm Job Postings Directors Room7:00 am – 7:00 pm Internet Stations-Sponsored by Springer Directors Room8:00 am – 7:00 pm Poster Session I-Posters up for 2 Days Rio/Medina/Guadalupe

Authors Present 5:45 pm—6:45 pm8:00 am – 9:30 pm General Session Regency Ballroom

Basic Neurochemistry Lecture by Philip Haydon9:30 am – 5:30 pm ASN Scientific Sessions Ballrooms12:00 pm – 1:00 pm Lunch with Philip Haydon Pecan Room

Tickets $20/$15—Limited Seating12:00 pm – 1:00 pm Journal of Neurochemistry Editors Lunch Chula Vista Boardroom5:30 pm – 7:00 pm Poster Presentations (Authors Present) Rio/Medina/Guadalupe

Wine & Cheese ReceptionSponsored by Covance (CRP)

7:00 pm – 10:00 pm Student/Post-Doc Dinner Dick’s Last ResortSponsored by Wiley-Blackwell (Riverwalk)

Monday, March 37:00 am – 6:00 pm ASN Registration Desk Open Rio Foyer7:00 am – 5:00 pm Poster Session I Rio/Medina/Guadalupe

Authors Present 3:15 pm—4:15 pm7:00 am – 7:00 pm Job Postings Directors Room7:00 am – 7:00 pm Internet Stations-Sponsored by Springer Directors Room8:15 am – 6:30 pm ASN Scientific Sessions Ballrooms12:00 pm – 1:00 pm Lunch with Jeffrey Rothstein— Pecan Room

Tickets $20/$15—Limited Seating12:00 pm – 1:00 pm Women in Neurochemistry (WIN) Luncheon— Live Oak Room

Speaker Sponsored by Wiley-Blackwell, Tickets $20/$1012:00 pm – 1:00 pm Neurochemical Research Editors Lunch Acenar Restaurant3:15 pm – 4:15 pm Poster Presentations (Authors Present) Rio/Medina/Guadalupe6:45 pm – 8:30 pm ASN Business Meeting — All Members Invited Live Oak Room

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2008 Agenda-At-A-Glance2

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Tuesday, March 46:45 am – 8:00 am 09 Scientific/Host Committee Meeting Pecan Room7:00 am – 6:00 pm ASN Registration Desk Open Rio Foyer7:00 am – 7:00 pm Job Postings Directors Room7:00 am – 7:00 pm Internet Stations-Sponsored by Springer Directors Room8:00 am – 7:00 pm Poster Session II-Posters up for 2 Days Rio/Medina/Guadalupe

Authors Present 5:45 pm—6:45 pm8:15 am – 5:30 pm ASN Scientific Sessions Ballrooms12:00 pm – 1:00 pm Lunch with Jeffrey Macklis— Pecan Room

Tickets $20/$15—Limited Seating12:00 pm – 1:00 pm JNR Editors Lunch Live Oak Room5:30 pm – 7:00 pm Poster Presentations (Authors Present) Rio/Medina/Guadalupe

Margarita ReceptionSponsored by Sonofi-Aventis

7:00 pm – 9:00 pm Handbook of Neurochemistry and Paesano’s RestaurantMolecular Neurobiology (Riverwalk)

Wednesday, March 57:00 am – 3:00 pm ASN Registration Desk Open Rio Foyer7:00 am – 2:30 pm Poster Session II Rio/Medina/Guadalupe

Authors Present 1:30 pm—2:30 pm7:00 am – 5:30 pm Job Postings Directors Room7:00 am – 5:30 pm Internet Stations-Sponsored by Springer Directors Room8:15 am – 5:30 pm ASN Scientific Sessions Ballrooms12:00 pm – 1:00 pm Lunch with Marie Filbin— Pecan Room

Tickets $20/$15—Limited Seating12:30 pm – 2:30 pm ASN Council Meeting Mesquite Room1:30 pm – 2:30 pm Poster Presentations (Authors Present) Rio/Medina/Guadalupe7:00 pm – 10:00 pm ASN Closing Party Regency Ballroom

Page 5: AMERICAN SOCIETY FOR NEUROCHEMISTRY...©2008 American Society for Neurochemistry Terri Wood, Chair Regina Armstrong Stephen Back Scott Barnum Scott Brady Monica Carson American Society

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y7:00 am – 7:00 pm ASN Registration Desk Open Los Rios Foyer

3:00 pm – 7:00 pm Internet Stations-Sponsored by Springer Directors Room

3:00 pm – 7:00 pm Job Postings/Placement Information Directors Room

8:15 am – 5:00 pm Pre-Meeting Workshop Regency EastGlial-Neuronal Interactions:Cutting Edge Approaches toModeling CNS Function and Disease

8:15 am – 8:30 am Welcome and Workshop Introduction,Monica J Carson, President

8:30 am – 9:00 am Presentation and Discussion —The NIH view of Glial-Neuronal Interactions:Presentation and Discussion of the New Glial-focusedNIH Study Sections and Program Initiatives

9:00 am – 12:00 pm ISN Symposium:Detecting and Analyzing the Consequences ofGlial-Neuronal Interactions

9:00 am – 10:00 am Keynote Presentation— R. Douglas Fields, PhD:Myelin: Plasticity Beyound the Synapse

10:00 am – 10:30 am Coffee-Discussion Break

10:30 am – 11:15 am Richard Ransohoff, MD:Chemokines and Chemokine Receptors Regulate Glial Responsesto Neural Injury

11:15 am – 12:00 pm Vlad Parpura, MD, PhD:Tripartite Synapse-astrocytic Regulation of Glutamate

12:00 pm – 1:15 pm Lunch for Registered Workshop in Garden TerraceAttendees and Speakers

1:15 pm – 4:45 pm Glial-Neuronal Interactions: Applications to Infectious Disease

1:15 pm – 2:00 pm Bruce Chesebro, MD:Differing Roles of Microglial and Astroglial Prion ProteinExpression in Scrapie-induced Neurodegeneration in Retina and Brain

2:00 pm – 2:45 pm Ken Williams, PhD:Monocytes and Macrophages in the CNS, the Role of Myeloid Cellsin NeuroAIDS

2:45 pm – 3:15 pm Coffee-Discussion Break

3:15 pm – 4:00 pm Mario Philipp, PhD:Glial Cells in the Pathogenesis of Lyme Neuroborreliosis

4:00 pm – 4:45 pm Tammy Kielian, PhD:Glial Responses to Staphylococcus Aureus in the CNS

4:45 pm – 5:00 pm Workshop Wrap-up and Concluding Comments:Vlad Parpura, MD, PhD

4:30 pm – 6:30 pm Public Forum — Focus on Parkinson’s Disease— Chula Vista RoomCurrent and Emerging Concepts

6:30 pm – 8:00 pm ASN President’s Reception Regency Ballroom

Saturday, March 1 , 2008

American Society for NeurochemistryThe Latest in Molecular and Cellular Neurobiology

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7:00 am – 7:00 pm ASN Registration Desk Open Los Rios FoyerPosters must be set-up by 7:30 am

7:00 am – 7:00 pm Internet Stations-Sponsored by Springer Directors Room

7:00 am – 7:00 pm Job Postings/Placement Information Directors Room

8:00 am – 7:00 pm Poster Session I Rio/Medina/Guadalupe

8:00 am – 8:30 am General Session Regency BallroomWelcome - Monica Carson, President

New Members RecognitionTravel Awardees Recognition

Bernard Haber Award PresentationWinner - Jean deVellis

8:30 am – 9:30 am Plenary Speaker-Basic Neurochemistry Lecture Regency BallroomPhil Haydon, Ph. D.The Tripartite Synapse: Roles For AstrocytesIn The Control Of Synapses, Networks And Behavior

9:30 am – 10:00 am Break Rio/Foyer

10:00 am – 12:00 pm ASN Scientific Sessions:

12:00 pm – 1:00 pm Lunch with Speaker—Phil Haydon Pecan RoomSponsored by ISNPurchase Tickets at ASN Registration Desk

12:00 pm – 1:00 pm Journal of Neurochemistry Editors Lunch Live Oak Room

Sunday, March 2 , 2008

Regency West Regency EastRegency Center

Symposium S01The ER Stress Response inNeurological DisordersChair: Brian Popko

S01-01 Duennwald, M.L.ER Stress Is A Major ContributorTo Polyglutamine Toxicity

S01-02 Nave, K.A.Abnormal Interactions Of MyelinProteins With Cholesterol In MouseModels Of Leukodystrophy AndNeuropathy

S01-03 Nakamura, T./Lipton, S.A.S-Nitrosylation, ER Stress,And Protein Misfolding InNeurodegenerative Disease

S01-04 Popko, B.ER Stress Modulates The ResponseOf Oligodendrocytes To Inflammation

Symposium S02Regulation of AsymmetricDivisions and Cell Polarity inNeural Stem Cells and Neurons Chairs: Erhard Beiberich and

Steve Levison

S02-01 Zhong, W.Asymmetric Cell Division AndStem-Cell HomeostasisS02-02 Zheng, Y.Distinct Roles Of The Rho FamilyGTPases Cdc42 And Rac1 In NeuralProgenitor Regulation DuringForebrain DevelopmentS02-03 Bieberich, E. Ceramide Regulates Neural StemCell PolarityS02-04 Xiong, W. Myosin X Acts As A "Vehicle"For Neuronal Netrin Receptors

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The Latest in Molecular and Cellular Neurobiology

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Sunday, March 2 , 2008

Regency West Regency EastRegency CenterColloquium 1CO1 Role of Lipid-ProteinInteractions and StructuralDynamics in MitochondrialFunction Chairs: Mary McKenna and

Arne Schousboe

C01-01 Mannella, C.A.Topology And Dynamics Of TheMitochondrial Inner Membrane

C01-02 Csordás, G.Structural And Functional FeaturesAnd Significance Of The PhysicalLinkage Between ER AndMitochondria

C01-03 Golovko, M.Y.Alpha-Synuclein ModulatesMitochondrial Membrane PropertiesAnd Functions

C01-04 Mckenna, M.C.Role Of Lipids In Modulating TheActivity Of Mitochondrial AspartateAminotransferase A Key Enzyme InMetabolism

Colloquium 2C02 Life after transcription:RNA-mediated regulation innervous system development Chairs: Yue Feng and

Regina Armstrong

C02-01 Perrone-Bizzozero, N.I.The Neuronal RNA-Binding ProteinHuD Controls The CoordinatedExpression Of MultipleDevelopmentally-Regulated GenesIn Vivo

C02-02 Jin, P.Role Of MicroRNA PathwayIn Mental Retardations

C02-03 Klann, E. Post-Developmental Deletion OfTranslation Control Molecules AltersSynaptic Plasticity And Behavior

C02-04 Barbarese, E.The A2-Responsive Element At The3' UTR Of Myelin Basic ProteinmRNA Is Necessary For LongDistance Myelin Formation

C02-05 Feng, Y. Essential Function Of The SelectiveRNA-Binding Protein QKI In MyelinDevelopment

Colloquium 3C03 Immune Functions ofAstrocytes Chair: Tammy Kielian

C03-01 Benveniste, E.N.Expression And Function Of SOCSProteins In Astrocytes

C03-02 Lowenstein, P.R.CTL Function In The CNS:Immunological Synapses Induce AMajor Structural Reorganization OfTarget Virally Infected Astrocytes

C03-03 Bethea, J.R.Astroglial-NF-kB: A CriticalRegulator Of Astrogliosis AndInflammation In The CNS

C03-04 Kielian, T.L.Recognition Pathways And ImmuneResponses Elicited By MicrobialStimuli In Astrocytes

1:00 pm – 3:00 pm ASN Scientific Sessions: Sun

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3:00 pm – 3:30 pm Break Rio/Foyer

39th Annual MeetingSan Antonio, Texas – 2008

ASN Welcomes the following ExhibitorsTo the 39th Annual Meeting:

Covance (CRP)

Elsevier

Olympus

Springer

Wiley-Blackwell

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Sunday, March 2 , 20083:30 pm – 5:30 pm ASN Scientific Sessions:

5:30 pm – 7:00 pm Poster Presentation I & Exhibitors Rio/Medina/GuadalupeAuthors Present 5:45 to 6:45

Wine & Cheese Reception-Sponsored by Covance (CRP)

7:15 pm – 10:00 pm Student/Post-Doc Party Dicks Last ResortSponsored by Journal for Neurochemistry RiverwalkWiley-Blackwell Publishing-Ticket Required

Regency West Regency CenterWorkshop 1Cyclooxygenases:Protectors or Enhancersof Neuroinflammationand Neurodegeneration? Chairs: Francesca Bosetti

Sandra Hewett

W01-01 Hewett, S.J.Cyclooxygenase-2 (COX-2)Activation: Permissive OrPreventative InExcitotoxicity And Seizure?

W01-02 Anrather, J.The Interplay Of COX-1And COX-2 DerivedProstaglandins In TheDevelopment Of ExcitotoxicBrain Damage

W01-03 Andreasson, K.I.Function Of ProstaglandinReceptors In Models OfNeurological Disease

W01-04 Pasinetti, G.M.Inhibition OfCyclooxygenase As PotentialNovel Therapeutic StrategyIn N141I Presenilin-2Familial Alzheimer's Disease

W01-05 O'Banion, M.K.COX-1 And ProstaglandinReceptor EP2 Contribute ToNeuroinflammation CausedBy Sustained IL-1Expression

W01-06 Bosetti, F.Differential Roles OfCyclooxygenase-1 And -2 InLipopolysaccharide-InducedNeuroinflammation

Colloquium 4C04 Dynamic Cell-Extracellular MatrixAdhesions (FocalAdhesions) in NeuralDevelopmentChair: Babette Fuss

C04-01 Webb, D.J.Adhesion SignalingThrough Actin RegulatesThe Formation OfDendritic Spines AndSynapses In HippocampalNeurons

C04-02 Ethell, I.M.Focal Adhesion KinaseRegulates Dendritic SpineDevelopment InHippocampal Neurons

C04-03 Gomez, T.M.Retinotopic MappingRequires Fak-MediatedStabilization Of GrowthCone Adhesion

C04-04 Fuss, B.Focal AdhesionReorganization And ProcessOutgrowth In Differen-tiating Oligodendrocytes

Regency East Live Oak RoomColloquium 5C05 Neurobiology ofAutism Chair: Ved Chauhan

C05-01 Gargus, J.J.Mitochondrial Energy-Deficiency EndophenotypesIn Autism

C05-02 Herbert, M.R.Autism-Brain And Body:From Metabolism ToFunction To Structure

C05-03 Chauhan, A.Oxidative Stress AndInflammation In Autism

C05-04 James, S.J.Oxidative Stress And TheMetabolic Pathology OfAutism

C05-05 Fatemi, S.H.The Role OfNeurodevelopmental GenesIn Etiology And TreatmentOf Autism

Oral Presentations 1OP01 Myelin,Oligodendrocyte &Schwann Cell Biology Chairs: Lucia Notterpek

Juana Pasquini

OP1-01 Coelho, R.P. FTY720 Has A DirectCytoprotective Effect InOligodendrocyte Progenitors:Implications For TheTreatment Of MultipleSclerosis

OP1-02 Fressinaud, C.Axon Cytoskeleton ProteinsExert Specific Effects OnOligodendrocytes AndAstrocytes In Vitro

OP1-03 Yuelling, L.M. LPA, Generated ByPD-Ia/ATX'S LysopldActive Site, ContributesTo OligodendrocyteDifferentiation

OP1-04 Osterhout, D.J.Chondroitin SulfateProteoglycans InhibitMigration AndDifferentiation OfOligodendrocyte ProgenitorCells

OP1-05 Harauz, G.MBP As A "PIP2-Modulin"Protein: New BiologicalFunction For An Old CNSProtein

OP1-06 Connor, J.R.The Ferritin Binding ProteinOn Oligodendrocytes IsTim2

OP1-07 Silvestroff, L.Subventricular Zone-DerivedNeural Stem Cells AndOligodendogenesis

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The Latest in Molecular and Cellular Neurobiology

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Monday, March 3 , 2008

7:00 am – 5:00 pm ASN Registration Desk Open Los Rios Foyer

7:00 am – 5:00 pm Poster Session I Rio/Medina/Guadalupe

7:00 am – 7:00 pm Internet Stations-Sponsored by Springer Directors Room

7:00 am – 7:00 pm Job Postings/Placement Information Directors Room

8:15 am – 8:30 am General Session Regency BallroomJordi Folch Pi Award PresentationWinner-Tinna Kauppinen

8:30 am – 9:30 am Plenary Speaker -Sponsored by ISN Regency BallroomJeffrey D. Rothstein, M.D., Ph. D.Astroglial Dysfunction And DegenerativePeri-Synaptic Events: A Basis ForTherapeutics Development

9:30 am – 10:00 am Break Rio/Foyer

10:00 am – 12:00 pm ASN Scientific Sessions:

Regency West Regency EastRegency CenterSymposium S03Emerging Roles for Sphingolipidsin Neurodegenerative Disease Chair: Norman Haughey

S03-01 Nikolova-Karakashian, M.N.Functions, Metabolism, And GeneticsOf Bioactive Sphingolipids

S03-02 Mattson, M.P.Sphingomyelin And CeramideMetabolism In Neuronal PlasticityAnd Aging

S03-03 Dawson, G.Roles For Sphingolipids InNeurodegeneration And Myelination

S03-04 Hama, H.Fatty Acid 2-Hydroxylase (FA2H) InMyelination And Glial Cell Signaling

S03-05 Haughey, N.JRoles For Disordered SphingolipidMetabolism In The Pathogenesis OfHIV-Dementia

Symposium S04Glial Cells and NeurologicalDiseaseChair: Harold Sontheimer

S04-01 McCarthy, K.D.Overexpressing A Gi-Coupled GPCRIn Astrocytes Leads ToHydrocephalus

S04-02 Brenner, M.GFAP Mutations InAlexander Disease

S04-03 Sontheimer, H.Biological Changes That Support TheGrowth And Invasion Of MalignantGliomas

S04-04 Gallo, V.Endothelin-1 Regulates AstrocyteProliferation And Reactive Gliosis ViaA JNK/c-Jun Signaling Pathway

12:00 pm – 1:00 pm Lunch with Speaker—Jeffrey D. Rothstein Pecan RoomSponsored by ISNPurchase Tickets at ASN Registration Desk

12:00 pm – 1:00 pm Women in Neurochemistry Luncheon Live Oak RoomWorkforce for the Future: Retention ofWomen in Neuroscience - Dr. Alison HallSpeaker Sponsored by Wiley-Blackwell

12:00 pm – 1:00 pm Journal of Neurochemical Research Acenar RestaurantEditors Lunch Valencia Hotel

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1:00 pm – 3:00 pm ASN Scientific Sessions:

Monday, March 3 , 2008

Regency West Regency EastRegency Center

Colloquium 6 C06 The Microglia-NeuronalInterface: Dual Consequences forCNS Function duringInflammation and Regeneration Chairs: Jean Harry

Monica Carson

C06.01 Carson, M.J.Fine Tuning Microglial ResponsesToward Protection Or Destruction:The Role Of Microglial HeterogeneityAnd TREMs

C06.02 Trapp, B.Microglia Activation AndNeuroprotection During CNSPreconditioning

C06.03 Rosi, S.Neuroinflammation AndPharmacological Approaches ToRestore Neuronal-MicrogliaCommunication

C06.04 Harry, G.J.Injury-Induced Neurogenesis: CanMicroglia Offer Support To NewNeurons In The Subgranular Zone

Colloquium 7 C07 Neural Progenitor Cells inDevelopment and Neural Repair Chairs: Robert Yu

Frances Szele

C07.01 Yu, R.K.Glycobiology Of Neural ProgenitorCells: Functional Aspects

C07.02 Levison, S.W.Neural Stem Cells In Neural Repair

C07.03 Rutishauser, U.S.Polysialic Acid In Formation AndRepair Of The Nervous System

C07.04 Schwartz, N.B.Embryonic Glial Precursors:Associated Proteoglycans AndResponse To Embryonic Brain Injury

C07.05 Curtis, M.A.Migratory Neuroblasts In The HumanRostral Migratory Stream

C07.06 Baron-Van Evercooren, A.S.Boundary Cap Cells As A NovelSource Of Schwann Cells For MyelinRepair Of The Central NervousSystem

C07.07 Zecevic, N.Progenitor Cells In The Human FetalSubventricular Zone

Colloquium 8 C08 New Approaches to theTherapy of CNS Storage Disorders Chair: Ian Duncan

C08.01 Eckman, C. Enzyme Replacement Therapy ForGloboid Cell Leukodystrophy

C08.02 Kondo, Y. Hematopoietic Stem Cell-MediatedEx Vivo Gene Therapy In A MouseModel Of Krabbe's Disease

C08.03 Biffi, A. Hematopoietic Stem Cell Based GeneTherapy For The Treatment OfMetachromatic Leukodystrophy:Towards Clinical Testing

C08.04 Snyder, E. Therapeutic Horizons: Is There ARole For Neural Stem Cells (NSC's)Against Lysosomal Storage Diseases?

3:00 pm – 4:30 pm Poster Presentations & Exhibitors Rio/Medina/GuadalupeAuthors present 3:15-4:15

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American Society for NeurochemistryThe Latest in Molecular and Cellular Neurobiology

2008 Young Latin American Scholar Awards Award Winners

This Award is co-sponsored by the ISN and ASN to promising young neuroscientistsfrom Latin America to attend the Meeting and to visit a U.S. Laboratory for one week.

Celeste LealInstitute Lius Federico Leloir—Buenos Aires, Argentina

Lucas SilvestroffUniversity of Buenos Aires—Buenos Aires, Argentina

Page 11: AMERICAN SOCIETY FOR NEUROCHEMISTRY...©2008 American Society for Neurochemistry Terri Wood, Chair Regina Armstrong Stephen Back Scott Barnum Scott Brady Monica Carson American Society

Monday, March 3 , 2008

4:30 pm – 6:30 pm ASN Scientific Sessions:

Regency West Regency EastRegency Center

Workshop 2W02 Nanotechnology andNeuroscience Chair: Vlad Parpura

W02-01 Silva, G.A.Imaging Astrocytes UsingFunctionalized Quantum DotNanocrystals

W02-02 Parpura, V.Carbon Nanotubes And Neurons?

W02-03 Ballerini, L.Interfacing Cultured Brain CircuitsAnd Carbon Nanotubes: Impact OnSpontaneous And Stimulation-Induced Neuronal Signaling

W02-04 Romero, M.I.Neurointerfacing Through CarbonNanotube Yarns And Sheets

Colloquium 9 C09 Got Hormones? GenderDifferences in Glia and WhiteMatter Diseases Chairs: Robert Skoff

Christopher Gregg

C09-01 Skoff, R.Sexual Dimorphism OfOligodendrocytes: Morphological AndFunctional Properties

C09-02 McCarthy, M.M.The Role Of Astrocytes In TheEstablishment Of Sex Differences InThe Brain

C09-03 Gregg, C.G. White Matter Plasticity And EnhancedRemyelination In The Maternal CNS

C09-04 Voskuhl, R.R.Differential Neuroprotective AndAnti-Inflammatory Effects Of EstrogenReceptor (ER) Alpha And ER BetaLigand Treatment

Oral Presentations 2OP02 Neurotoxicity andNeurodegeneration Chairs: Evelyn Castiglioni

Marina Guizzetti

OP02-01Laing, J.M.Glial Cell Modulation Is AssociatedWith Neuroprotection By The HSVVector DeltaRR

OP02-02 Smith, M.A.Neurodegeneration Induced ByNeuronal Cell Cycle Re-Entry InCaMKII-MYC Transgenic Mice

OP02-03 Lungu, G.Up-Regulation Of ProNFG, P75NTR,And Sortilin Is Associated WithRetrovirus-Induced SpongiformEncephalomyelopathy

OP02-04 Clarke, D.Endorepellin And Endostatin AffectThe Neurovascular Unit In Vitro

OP02-05 Guizzetti, M.Ethanol And Retinoic Acid AffectCholesterol Homeostasis InAstrocytes: A New Mechanism OfDevelopmental Neurotoxicity?

OP02-06 Qian, Y.C.Differential Copper Metabolism AndToxicity In Human Neuronal AndGlial Cell Lines

OP02-07 Guyton, M.K.Calpain Inhibition AttenuatesImmunological And NeurodegenerativePathologies Of EAE

OP02-08 Berman, A.E.The Role Of EAAC1 InMesencephalic Dopaminergic Neurons

6:45 pm – 8:30 pm ASN Business Meeting Live Oak RoomAll Members Invited

Due to the cancellation of the 2007 Cancun Meeting, the following awards will be presented:2007 Marian Kies Award—Siming Shen 2007 Jordi Folch-Pi Award—Gerardo Morfini

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39th Annual MeetingSan Antonio, Texas – 2008

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Tuesday, March 4 , 2008

6:45 am – 8:00 am 09 Scientific/Host Committee Meeting Pecan Room

7:00 am – 5:00 pm ASN Registration Desk Open Los Rios FoyerPosters must be set-up by 7:30 am

7:00 am – 7:00 pm Internet Stations-Sponsored by Springer Directors Room

7:00 am – 7:00 pm Job Postings/Placement Information Directors Room

8:00 am – 7:00 pm Poster Session II Rio/Medina/Guadalupe

8:00 am – 8:15 am General Session Regency BallroomMarion Kies Award PresentationWinner - TBA

8:15 am – 9:30 am Plenary Speaker Regency BallroomJeffrey D. Macklis, M.D., D.HSTMolecular Development And Cellular RepairOf Corticospinal Motor Neuron (And OtherForebrain Projection Neuron) Circuitry

9:30 am – 10:00 am Break Rio/Foyer

10:00 am – 12:00 pm ASN Scientific Sessions:

Regency West Regency EastRegency CenterSymposium S05Central Nervous SystemMaintenance and Immune systemin Health and Disease Chair: Jonathan Kipnis

S05-01 Schwartz, M.Immune Cells And Immune-RelatedMolecules Expressed On AdultNeural Stem Cells Are Involved InMaintenance And Renewal Of TheCNS

S05-02 Weiner, H.L. Chronic Nasal Administration Of AProteosome-Based Adjuvant PreventsBeta-Amyloid Accumulation GivenAt Early Stages In A Mouse Model

S05-03 Popovich, P.G.Toll-Like Receptors And Spinal CordRepair

S05-04 Hanisch, U.K.TLR-Mediated Recruitment OfMicroglia

S05-05 Kipnis, J.Immune System As A PrerequisiteFor A Proper Brain Function

Symposium S06The Jordi Folch-Pi SymposiumAxonal Transport Defects inNeurodegenerative Diseases Chairs: Gerardo Morfini

Scott Brady

S06-01 Brady, S.T.Dysferopathies: NeurodegenerativeDiseases Characterized By AlterationsIn Fast Axonal Transport Mechanisms

S06-02 Pigino, G.F.Intracellular Amyloid Beta InhibitsFast Axonal Transport

S06-03 Roy, S.Axonal Transport And PresynapticTargeting Of Alpha-Synuclein:Implications For Synucleinopathies

S06-04 Baloh, R.H.Axonal Mitochondrial TransportDefects In Human PeripheralNeuropathy

S06-05 Morfini, G.A. Fast Axonal Transport Alterations InPolyglutamine-Expansion Diseases

12:00 pm – 1:00 pm Lunch with Speaker—Jeff Macklis Pecan RoomSponsored by ISNPurchase Tickets at ASN Registration Desk

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1:00 pm – 3:00 pm Scientific Sessions:

3:00 pm – 3:30 pm Break Rio/Foyer

Tuesday, March 4 , 2008

Regency West Regency EastRegency CenterColloquium C10Molecules and MechanismsRegulating Myelination Chairs: Haesun Kim

Jonah Chan

C10-01 Kim, H.A.Differential Modulation Of ERBBSignaling By Type II And Type IIINeuregulin1 Regulates Myelination

C10-02 Carter, B.D.Neuregulin1 Type III And PKAActivate NF-kB In Schwann Cells,Which Is Necessary For MyelinFormation

C10-03 Maurel, P. The Nectin-Like Proteins AreInternodal Adhesion MoleculesRequired For Myelination

C10-04 Chan, J.R.Neighbors You Can Count On: ANovel Role For IntercellularInteractions In OligodendrocyteDifferentiation

Colloquium C11Glia-Neuron Interaction:Astrocytes Regulate SynapticTransmission and Plasticity Chair: Tommaso Fellin

C11-01 Stellwagen, D.Glial Released TNFalpha Is AMediator Of Homeostatic SynapticStrengthening

C11-02 Bezzi, P. Modality And Significance OfGlutamate Exocytosis FromAstrocytes

C11-03 Oliet, S.H. D-Serine: A Key Gliotransmitter ForNMDA Receptor Activity In TheHypothalamus

C11-04 Fellin, T.Astrocytic Control Of NeuronalNetworks

C11-05 Robitaille, R.Glial Cells Govern The Outcome OfSynaptic Plasticity

Colloquium C12Neuroinflammation in ALS:Pathophysiology and TherapeuticTarget Chair: Brent Harris

C12-01 Harris, B.T. The Role Of Glia And CytokinesIn Cell Culture And Animal ModelsOf ALS

C12-02 Appel, S.Immunomodulation Of Motor NeuronInjury In The mSOD1 Mouse:A Central And Peripheral Event

C12-03 Hensley, K.Neuroinflammation As A ParadigmFor ALS Therapy Development

C12-04 Cleveland, D.W. Neuroinflammation And Non-CellAutonomous Death Of MotorNeurons In ALS

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Future ASN Meetings

40th ASN Annual Meeting — Charleston, SC, March 7—11, 2009

41st ASN Annual Meeting — Santa Fe, NM, March 6—10, 2010

42nd ASN Annual Meeting — St. Louis, MO, March 19—23, 2011

Check Website for Program Updates: www.ASNeurochem.org

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Tuesday, March 4 , 2008

Regency West Regency CenterWorkshop 3W03 Workshop onHistory ofNeurochemistry:Looking to the Past toLearn for the Future Chairs: Anne Boullerne

George De Vries

W03-01 Boullerne, A.I.History Of Neurochemistry:From The Pioneers ToToday, A GreatTechnological Revolution

W03-02 De Vries, G.H.Lessons From The Lipids:Their History And Role InNeurochemistry

W03-03 Quarles, R.H.Milestones In TheMyelin-AssociatedGlycoprotein Journey

Colloquium 13C13 LRRK2 inParkinson's Disease,a Target forNeuroprotection? Chairs: Jonathan Kern

Ian Reynolds

C13-04 Ross, OGenetics of LRRK2-Associated Parkinsonism

C13-01 Cookson, M.R.How Mutations In LRRK2Affect Kinase Activity, AndWhy It Matters

C13-02 Merchant, K.M. Characterization Of KinaseActivity And ToxicityOf Leucine-Rich RepeatKinase 2

C13-03 Dawson, T.M.Localization And BiologyOf Leucine-Rich RepeatKinase 2 Gene (LRRK2):Implications For FunctionAnd Pathogenesis

Regency East Live Oak RoomColloquium 14C14Marion Kies MemorialColloquium—Supported by ISN

Role of HistoneModification inNeurological DiseasesChair: Siming Shen

C14-01 Kazantsev, A.G. Development of SmallMolecule Inhibitors ofDeacetylasee Sirtuin 2For Treatment ofAggregate-AssociatedNeurodegenerative Diseases

C14-02 Renthal, W.Histone AcetylationControls BehavioralResponses To Cocaine

C14-03 Shen, S. Epigenetic Regulation OfOligodendrocyteDifferentiation Inhibitors IsEssential For SuccessfulRemyelination

C14-04 Yao, T.P.Protein DeacetylaseHDAC6 In ProteinAggregate Clearance AndNeurodegeneration

Oral Presentations 3OP03 Microglia in thePathophysiology of CNSDisorders Chairs: Maria Nikodemova

Bonnie Dittel

OP03-01 Kane, C.J.Microglial Cells AndPPAR-Gamma AgonistsProtect Neurons AgainstEthanol Neurotoxicity

OP03-02 Syapin, P.J. Astrocyte-StimulatedMigration By HumanCHME-5 Microglia

OP03-03 Hsieh, C.L.A Requirement For TREM2Ligands In The PhagocytosisOf Neuronal Cells ByMicroglia

OP03-04 Xu, J. Regulation Of CNSInflammation By PeroxisomeProliferator-ActivatedReceptor-Alpha AgonistFenofibrate

OP03-05 Li, J.TNF, But Not Peroxynitrite,Mediates Microglial ToxicityTo DevelopingOligodendrocytes WhenAstrocytes Are Present

OP03-06 Mishra, M.K.Minocycline ConfersComplete Protection AgainstJapanese Encephalitis:Correlation With MicroglialActivation & NeuronalApoptosis

3:30 pm – 5:30 pm Scientific Sessions:

5:30 pm – 7:00 pm Poster Presentation II & Exhibitors Rio/Medina/GuadalupeAuthors Present 5:45 to 6:45

Margarita Reception-Sponsored by Sonofi-Aventis

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Wednesday, March 5 , 2008

7:00 am – 5:00 pm ASN Registration Desk Open Los Rios Foyer

7:00 am – 5:00 pm Internet Stations-Sponsored by Springer Directors Room

7:00 am – 5:00 pm Job Postings/Placement Information Directors Room

7:00 am – 2:30 pm Poster Session II Rio/Medina/Guadalupe

8:00 am – 5:30 pm ASN Scientific Sessions:

Plenary Speaker at 4:30 pm – 5:30 pm Regency WestMarie Filbin, Ph.D

Signaling Axonal Regeneration InThe Injured Spinal Cord

8:00 am – 10:00 am ASN Scientific Sessions:

Regency West Regency CenterSymposium S07Novel Strategies for Plasticity andRepair after Spinal Cord Injury Chairs: Dana McTigue,

David Shine, Armin Blesch

S07-01 Zheng, B.Genetic Mouse Models In StudyingInhibitors Of Spinal AxonRegeneration

S07-02 Mi, S. LINGO-1 And Its Role In AxonRegeneration And Myelination

S07-03 Shine, H.D. NT-3 And Neuroplasticity After SCI

S07-04 Blesch, A.Modulating Regenerative ResponsesAt Cell Soma And Axon After SpinalCord Injury

S07-05 Tetzlaff, W.Therapeutic Every Other Day FastingImproves Recovery From CervicalAnd Thoracic Spinal Cord InjuriesIn Rats

Regency EastSymposium S08Regulation of Neural ProgenitorCell Development Chairs: Tarik Haydar

Joshua Corbin

S08-01 Haydar, T.F. The Proliferation And LineagePotential Of Multiple Populations OfNeural Precursors In The EmbryonicMammalian Ventricular Zone

S08-02 Corbin, J.G.Origin And Migration Of MammalianAmygdala Neural Progenitor Cells

S08-03 Lillien, L. Akt1 Expression Level RegulatesCNS Precursors

S04-04 Juliano, S.L.Converging Mechanisms MediateRadial Glia Morphology, Migration OfNeurons Into The Cortex AndPosition Of Cajal Retzius Cells

S08-05 Gaiano, N.R. DifferentialNotch Signaling In Neural Stem AndProgenitor Cells During ForebrainDevelopment

10:00 am – 10:30 am Break Rio/Foyer

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10:30 am – 12:30 pm ASN Scientific Sessions:

Wednesday, March 5 , 2008

Regency West Regency EastRegency CenterColloquium C15Epigenetic Control of NeuralDevelopment Chair: Patrizia Casaccia-Bonnefil

C15-01 Fan, G. DNA Hypomethylation ImpairsNeuronal Excitability And InducesCortical Degeneration DuringPerinatal Development

C15-02 Kondo, T.Molecular Mechanism Of Sox2Expression In Telencephalic NeuralStem Cells

C15-03 Hsieh, J.HDAC Regulation Of AdultNeurogenesis

C15-04 Svaren, J.P. Active Gene Repression By TheEGR2/NAB Complex DuringPeripheral Nerve Myelination

C15-05 Atanasoski, S. The Function Of TheProto-Oncogene Ski InNeurodevelopment AndNeurodegeneration

Colloquium C16The Complement Cascade:Yin-yang in Neuroinflammation:Neuro-protection andDegeneration Chairs: Andrea Tenner

Jessy Alexander

C16-01 Tenner, A.J.Neuroprotective And NeurotoxicRoles Of The Complement ProteinC1q In Alzheimer Disease

C16-02 Stevens, B. The Classical Complement CascadeMediates CNS Synapse Elimination

C16-03 Alexander, J.J.Anaphylatoxin Receptor-MediatedSignaling Plays A Key Role InExperimental Lupus Cerebritis

C16-04 Anderson, A.Role Of Complement InNeurodegeneration AndNeuroregeneration After SpinalCord Injury

C16-05 Barnum, S.R.The Role Of CR3 And CR4 OnT Cells In Demyelinating Disease

Colloquium C17Novel Roles of EnergyMetabolites and Nutrient-SensingSystems in Energy Balance,Memory, and Diseases:A New Perspective ofFunctional Metabolism Chair: Gerald Dienel

C17-01 Gold, P.E. Regulation Of Memory By Glucose:Role In Age-Related MemoryImpairments

C17-02 Roopra, A.S. Metabolic Regulation Of NeuronalGenes By NRSF/CTBP: TherapeuticImplications For Epilepsy

C17-03 Ronnett, G.V. AMP-Activated Protein Kinase InThe Brain: A Regulator Of EnergyBalance And Neuroprotection

C17-04 Roe, C.R.Anaplerotic Therapy And NutrientSensor Interactions: Experience WithInherited Biochemical Disorders

12:30 pm – 1:30 pm Lunch with Speaker—Marie Filbin Pecan RoomSponsored by ISNPurchase Tickets at ASN Registration Desk

12:30 pm – 2:30 pm ASN Council Meeting Mesquite Room

1:30 pm – 2:30 pm Poster Presentation & Exhibitors Rio/Medina/GuadalupeAuthors present 1:30-2:30 pm

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2:30 pm – 4:15 pm ASN Scientific Sessions:

Regency West Regency CenterWorkshop 4 W04 Workshop onScientific CareersOutside of Academia Chair: Heather Arnett

Mixed presentation and opendiscussion on: 1) Pathways, Consequences

and Rewards to Careersin Big Pharma versusEmerging Biotech

2) Is the route out ofAcademia a one wayroad?

Facilitators: Heather Arnett, Sr. Scientist,Amgen Inc.

David Lo, DistinguishedProf, UCR;Past-Vice President DGTand Past-Director, Neurome

Oral Presentaitons 4 OP04: Roles forEndogenous Transmittersin NeurodegenerativeDiseases Chairs: Doug Feinstein

Howard Liu

OP04-01 Liu, H.H. Phosphorylation OfGlutamate Receptors AndChronic GlucocorticoidStress

OP04-02 Wu, J.Y. Mechanism And TherapyOf GranulocyteColony-Stimulating FactorIn Parkinson's Disease

OP04-03 Baganz, N.L. Organic CationTransporters: The AnswerTo The Uncertainty OfAntidepressant ResponseRevealed?

OP04-04 Knapp, P.E.Vulnerability Of GlialPrecursors &Oligodendrocytes ToHIV-1 Tat: InteractionsWith Morphine

OP04-05 Mufson, E.J. Nerve Growth FactorReceptor Dysfunction InEarly AD

OP04-06 Feinstein, D.L.Neuroprotective Effects OfNoradrenaline

Regency East Live Oak RoomOral Presentaitons 5 OP05: Glia andInflammation Chair: G. Mill Jonakait

OP05-01 Smith, S.E. Interleukin-6 MediatesThe Effects Of MaternalImmune Activation OnThe Behavior And GeneExpression Of TheOffspring

OP05-02 Ghiani, C.A. Maternal SystemicInflammation: Effects OnNeural Progenitor Cells

OP05-03 Irani, D.N. IL-1 Beta Mediates LossOf Astroglial GlutamateTransporter In The SpinalCord During ViralEncephalomyelitis

OP05-04 Liu, S.MyD88-DependentPathways Are ImportantFor Microglial AndAstrocyte Responses ToCitrobacter Koseri

OP05-05 Roy, A.Increase In NeurotrophinsIn Glial Cells By MyelinBasic Protein-Primed TCells Via AlphaV Beta3Integrin

Oral Presentations 6 OP06: Late BreakingAbstractsChairs: Robert Romanelli

Claudia Kaiser

OP06-01 Wang, G. Elevation of Long-ChainCeramide in Presenilin 1Knock-in Mouse Brain Induces Apoptosis in PS1Astrocytes

OP06-02 Pitt, D. Excitotoxic Injury toAxons is Mediated by GlialReactive Oxygen Species (ROS)

OP06-03 Pathmajeyan, M.S. Influence of Prion ProteinExpression on GlutamateUptake in Primary Astrocytes

OP06-04 Maezawa, I.Rett Syndrome Astrocytes areAbnormal and Spread theMeCP2 Deficiency State through Gap Junctions

OP06-06 Gouw, A.M.The Reprogramming ofNeuroglia into Neuronsthrough Epidermal Growth Factor and Curcumin

OP06-05 Pandey, S.C.A Role of Brain ChromatinRemodeling in Alcoholism

4:30 pm – 5:30 pm Plenary Speaker Regency WestMarie Filbin, Ph.DSignaling Axonal Regeneration InThe Injured Spinal Cord

7:00 pm – 10:00 pm ASN Closing Party Regency EastEntertainment-Max Class & Class Act

Wednesday, March 5 , 2008

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2008 Sponsors

The American Society for NeurochemistryAcknowledges the Generous Support from the Following Sponsors

Amaxa Biosystems

Amgen

Autism Speaks

Avanti Polar Lipids

Basic Neurochemistry Textbook

Biogen IDEC

BioLabs

Celgene Corporation

Center for Glial BiologyIn Medicine

Covance (CRP)

Elan

Elsevier

EMD Serono

Genzyme

International Societyfor Neurochemistry

Journal for Neurochemistry

KARGER

Matreya

Merck Research Labs

Millipore-Bioscience Divison

National Institutes of Health

National Multiple SclerosisSociety

New England Biolabs

NINDS

Olympus America

Quidel Corporation

Sanofi-Aventis Pharmaceuticals

Springer

Teva Neuroscience

Univ of Arkansas DeptNeurobiology

Univ Arkansas for

Medical Sciences

Univ of Chicago

Jack Miller Center

Wiley-Blackwell

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American Society for NeurochemistryThe Latest in Molecular and Cellular Neurobiology

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Impact Factor®

4.260

Published by Wiley-Blackwell on behalf of theInternational Society for Neurochemistry (ISN)

Fifty years since inception, Journal of Neurochemistry continues to be a leading source for research into all aspects of neuroscience, with a particular focus on molecular and cellular aspects of the nervous system, and is devoted to the prompt publication of original findings of the highest scientific priority and value.

Journal of Neurochemistry is pleased to sponsor the post-doc dinner at ASN 2008!

Visit the Wiley-Blackwell exhibition booth at the Annual ASN Meeting to:

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17

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A Conference Hosted by theCenter for Glial Biology in MedicineUniversity of Alabama at BirminghamDecember 1-3, 2008

For meeting information contact:Anne WailesUAB Center for Glial Biology in Medicine1719 6th Avenue SouthBirmingham, AL 35294-0021

Phone: 205.975.0259Fax: 205.975.6330Email: [email protected]: www.glia.uab.edu

Richard Ransohoff

Stephen Traynelis

Moses Chao

Bruce Ransom

Helmut Kettenman

Philip Haydon

Jeffrey Rothstein

Linda Watkins

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Rio/Medina/Guadalupe

NO PHOTOGRAPHY ALLOWED OF POSTERSAuthors Present

5:45pm—6:45pm Sunday • 3:15pm—4:15pm Monday

PSM01 Poster Session 1Neurotoxicity & Neurodegeneration

PSM01-01 Watson, J.B. Alterations In Synaptic Plasticity AndSynaptic Signaling In alpha-SynucleinMouse Models For Parkinson'sDisease

PSM01-02 Yao, T.P.Hdac6 And The Clearance OfToxic Protein Aggregates InNeurodegenerative Disease

PSM01-03 Smith, M.A. The Senescence Accelerated Mouse(SAMP8) As A Model To DetermineEarly Pathological Changes InAlzheimer Disease

PSM01-04 Smith, M.A. Abnormalities In MitochondrialFission And Fusion In AlzheimerDisease Fibroblasts And Neurons

PSM01-05 Davis, L.K.Apoptosis In Murine HypothalamusNeurons Exposed ToDihydroartemisinin: Possible RoleOf The Extrinsic Pathway

PSM01-06 Allam, K.K.Drugging The Undruggable:Development Of PhotodynamicTherapy And Boron Neutron CaptureTherapy Agents To Treat BrainTumors

PSM01-07 Zwingmann, C.Protective Effect Of L-Carnitine InHepatic Encephalopathy By NMR:Improvement Of Mitochondrial AndFatty Acid Metabolism

PSM01-08 Dinesh, D.K.Can DTI Predict Lesion DevelopmentIn Multiple Sclerosis?

PSM01-09 Zhang, L. 4-Hydroxy-2-Nonenal InhibitsFunction Of Rat StriatalSynaptosomes

PSM01-10 (OP02-03) Lungu, G. Up-Regulation Of ProNGF, P75NTR,And Sortilin Is Associated WithRetrovirus-Induced SpongiformEncephalomyelopathy

PSM02 Poster Session 2Aging

PSM02-01 Watts, L.T.Role Of GSH Production InG-Protein Receptor EnhancedAstrocyte NeuroprotectionDuring Aging

PSM02-02 Dienel, G.A.Efflux Of Amyloid-Beta1-40 viaPerivascular Routes From InferiorColliculus Of Normal Rats

PSM02-03 Zheng, W.In Vivo Neuroprotective Role OfAstrocyte Mitochondrial MetabolismDuring Rose Bengal-Induced CerebralInfarcts In Mouse Cortex

PSM02-04 Pieke-Dahl, S. Identification Of Genetic LociAssociated With Changes InLocomotor Activity For Mice AtMiddle And Old Age

PSM03 Poster Session 3Death and Survival

PSM03-01 Armstrong, R.C. Musashi1 RNA-Binding ProteinRegulates Oligodendrocyte LineageCell Differentiation And Survival

PSM03-02 Balabanov, R.Stat1/IRF-1 Signaling Pathway IsCritical For IFN-gamma-InducedOligodendrocyte Cell Death

PSM03-03 Ranasinghe, B. Efficacy Of Curcumin In EliminatingBrain Tumor Cells

PSM03-04 Das, A.Combination Of Retinoid AndFlavonoid For Inducing DifferentiationAnd Apoptosis In Malignant AndNonmalignant Neuroblastoma Cells

PSM03-05 Bu, L.Epithelial Fatty Acid Binding Protein(E-FABP) Is An EndogenousAntioxidant In PC12 Cells UnderOxidative Stress

PSM03-06 Qin, J.Palmitoyl:Protein Thioesterase (PPT1)Protects Against Cell Death InducedBy Neutral Sphingomyelinase 2

PSM03-07 Gorbet, J.TNF Alpha Affects Cellular DeathCascades By Ganglioside GD3Redistribution To The Mitochondria

PSM03-08 Almaguel, F.G.Modulation Of Palmitic Acid-InducedLipotoxicity (PA-LTx) In Neurons

PSM03-09 Xin, J. Investigation Of CD4+T Cell-Mediated NeuroprotectionIn A Mouse Model Of Facial NerveAxotomy

PSM04 Poster Session 4Gene Expression, Signaling &Cytoskeleton

PSM04-01 Uranga, R.M. Oxidative Stress TriggersPhosphoinositide-3-Kinase/AktActivation In Rat Cerebral CortexSynaptic Endings

PSM04-02 Purkayastha, S. Differentially Expressed PKCIsozymes May Regulate Stage SpecificHippocampal Development

PSM04-03 Mogha, A.PKC-Epsilon And 5-HT1A ReceptorCoupling To The MAPK Pathway InEarly Post-Natal Mouse Hippocampus

PSM04-04 Vemuganti, R.MicroRNA Profiling In Stroke

PSM04-05 Haines, J.D. P38 Mitogen Activated Protein KinaseRegulates OligodendrocyteDifferentiation

PSM04-06 Aronstam, R.S.Influence Of S-Nitrosylation OfMembranes Proteins On MuscarinicReceptors In Brainstem AndCHO Cells

PSM04-07 Zhang, R.Differential Sensitivity Of HumanGlioblastoma LN18 (PTEN-Positive)And A172 (PTEN-Negative) Cells ToTaxol For Apoptosis

PSM04-08 Norenberg, M.D.Oxidative/Nitrosative Stress, ThePermeability Transition And MAPKinases In The Mechanism Of BrainEdema In Acute Liver Failure

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Rio/Medina/Guadalupe

PSM05-03 Yao, J.K. Arachidonic Acid And NiacinSensitivity In Schizophrenia

PSM05-04 Luoma, A.M.Differential Effects Of Systems ThatGenerate Reactive Oxygen Species OnPNS Myelin

PSM05-05 Gorbet, J.C.Analysis Of Ganglioside BiosynthesisIn Primary Hippocampal NeuronsUsing RNAi Gene Silencing

PSM06 Poster Session 6Metabolism

PSM06-01 Waagepetersen, H.S.Is Neuronal Utilization Of GlucoseAnd Lactate Linked ToCa2+-Dependent Modulation OfMalate-Aspartate Shuttle Activity?

PSM06-02 Hansen, S.L. Effect Of Acute Injections Of TheKetone Bodies In PTZ Kindled Mice

PSM06-03 Kiebish, M.A. Mitochondrial Lipidome And ElectronTransport Chain Alterations InNon-Metastatic And MetastaticMurine Brain Tumors

PSM06-04 Nautiyal, M.Expression Of NIPSNAP1 In RatBrain: A Comparative Study With TheBranched-Chain Amino Acid (BCAA)Metabolizing Enzymes

PSM06-05 Safyan, R. The Role Of Peroxisomal LipidMetabolism In Cerebellar PurkinjeCell Development

PSM06-06 Kodavanti, P.S.Effects Of Brominated FlameRetardants On Calcium BufferingMechanisms In Rat Brain In Vitro

PSM06-07 Gawryluk, J.W.Effects Of Ketogenic Diet On LevelsOf High-Energy Brain Metabolites

PSM06-08 Garg, S.K. Role Of T Cell-Derived Glutamate InNeuroprotection By Astrocytes

PSM06-09 Singh, I.PPAR-Alpha Agonist InducedMultifunctional Enzyme-2Posttranslational Modification:Implications For PeroxisomalProliferation

PSM06-10 Walss-Bass, C. Clozapine-Induced Oxidation OfProteins Involved In EnergyMetabolism: A Possible MechanismFor Drug-Induced MetabolicAlterations

PSM07 Poster Session 7Spinal Cord

PSM07-01 Taira, E. Advanced Analysis Of GicerinExpression In The Rat SensoryNervous System

PSM07-02 Chen, Q.Immune-Mediated Wound Healing IsRequired For NT-3-InducedNeuroplasticity In Injured Spinal Cord

PSM07-03 Samantaray, S. Melatonin Prevented Neuronal DeathAnd Axonal Damage In Spinal CordInjury In Rats

PSM08 Poster Session 8Myelin, Oligodendrocyte andSchwann Cell Biology

PSM08-01 Gow, A. Tight Junction Function In SmallMyelinated Axons

PSM08-02 Paez, P.M.Regulation Of Ca2+ Entry IntoOligodendrocytes By Golli ProductsOf The MBP Gene

PSM08-03 Campagnoni, C.Myristoylated Fragment Of TheGolli-MBP Protein In Mouse Brain

PSM08-04 Eviatar-Ribak, T. Myelin Basic Protein PromoterInteractions And RemodelingDuring Myelination

PSM08-05 Boggs, J.M. Myelin Basic Protein Binds TheSH3-Domain Of Fyn Tyrosine KinaseTo A Membrane Surface

PSM04-09 Shivachar, A.C.Endocannabinoids Modulate AstroglialGlutamate Transport Via AMAPK-Mediated Signaling Pathway

PSM04-10 Carson, J.H.Multiplexed Dendritic Targeting OfRNAs By The A2 Pathway

PSM04-11 Sivaswamy, S.PKC And Focal Adhesion Kinase(FAK): Possible Transducer Roles InEthanol Preconditioning-InducedNeuroprotection From HIV-1 GP120

PSM04-12 Marini, A.M. Activity-Dependent BDNFTranscription Involves Relief OfBHLHB2-Mediated Repression

PSM04-13 Montana, V.Monitoring Calcium Ion DependenceOf Proteins Involved In NeuronalRegulated Exocytosis At A SingleMolecule Level

PSM04-14 Ram, S. High Resolution 3D Single MoleculeImaging Of Exocytosis AndEndocytosis In Living Cells WithMultifocal Plane Microscopy

PSM04-15 Sifonios, L.Enriched Environment Reverses TheDespair Behaviour, The Decrease InLight Neurofilament And SynapticMarkers In Rat Hippocampus

PSM04-16 Aschrafi, A.Brain-Specific MicroRNA-338Regulates Oxidative PhosphorylationIn The Axons Of SympatheticNeurons

PSM04-17 Seifert, J.L.Actin Binding Protein ComplexesRegulated By Rac1/Cdc42

PSM05 Poster Session 5Lipids & Membranes

PSM05-01 Petro, K.A.Effects Of Lipid MicrodomainDisruption On MurineNeuroblastoma Cells

PSM05-02 Levano, K.S. Mus Musculus ATP8A1 and ATPase1B And Plasma MembranePhosphatidylserine TranslocationIn Neuronal Cells

NO PHOTOGRAPHY ALLOWED OF POSTERSAuthors Present

5:45pm—6:45pm Sunday • 3:15pm—4:15pm Monday

37th Annual Meeting—San AntonioPosters

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Rio/Medina/Guadalupe

NO PHOTOGRAPHY ALLOWED OF POSTERSAuthors Present

5:45pm—6:45pm Sunday • 3:15pm—4:15pm Monday

PSM08-06 Ishii, A. Proteomic Analysis Of MouseMyelin-Axolemmal Subfractions

PSM08-07 Hankins, D. Life-Long Calorie RestrictionAttenuates Age-Related Changes InMyelinated Peripheral Nerves

PSM08-08 Padilla, A. Characterization Of PalmiticAcid-Induced Lipotoxicity OnImmortalized Schwann Cells

PSM08-09 Vogel, K.S. Age-Related Declines In DNA RepairCapacity In Murine Schwann Cells

PSM08-10 Narvaez, D.C. Age-Related Alterations In ProteinHomeostatic Mechanisms May ImpactThe Progression Of HereditaryPeripheral Neuropathies

PSM08-11 Pomicter, A.T. Novel Developmental Expression AndDistribution Of Neurofascin 155

PSM08-12 Shroff, S.M. Oligodendrocyte Development AndMyelination In The Absence OfSulfatide

PSM08-13 Furusho, M. The Essential Role Of Fgfr1 AndFgfr2 For The Generation OfOligodendrocyte Progenitors In TheEmbryonic Forebrain

PSM08-14 Min, J. IGF-1 Coordinates With FGF-2 ToEnhance S And G2/M PhaseProgression In OligodendrocyteProgenitor Cells

PSM08-15 Tyler, W.A. Activation Of mTOR Is Essential ForOligodendrocyte Differentiation

PSM08-16 Simonishvili, S.Modulators Of Bax-MediatedApoptosis In Glutamate-MediatedExcitotoxicity Of OligodendrocyteProgenitors

PSM08-17 Benjamins, J.Metabotropic Glutamate ReceptorsRegulate Diverse Pathways AndDecrease Receptor Levels To ProtectOligodendroglia

PSM08-18 Paintlia, M.Modulation Of PeroxisomeProliferator-Activated Receptor-AActivity By N-Acetyl CysteineAttenuates LipopolysaccharideInduced Inh

PSM08-19 Qin, J.Expression Of The Receptor ForAdvanced Glycation End Products(RAGE) In Oligodendrocytes InResponse To Oxidative Stress

PSM08-20 Preston, M.A.Novel Mechanisms UnderlyingHyaluronan Mediated RemyelinationFailure

PSM08-21 Pereira, B. Targeted Deletion Of TheAntisilencer/Enhancer RegulatoryElement From Intron 1 Of TheMouse Myelin Plp1 Gene

PSM08-22 Chew, L.J. p38 Mitogen Activated Protein (MAP)Kinase Regulates OligodendrocyteDevelopment

PSM08-23 Narayanan, S.P. Overexpression Of Akt InOligodendrocytes MediatesHypermyelination In The CNS RatherThan Cell Survival

PSM08-24 Waseen, A.T. Strange Bedfellows-Myelin/OligodendrocyteGlycoprotein And Stathmin,A Microtubule-Destabilizing Protein

PSM08-25 Tsoa, R.W. To Be Or Not To Be? TheFate-Determination Of NG2+ Cells.

PSM08-26 (OP01-02) Fressinaud, C. Axon Cytoskeleton Proteins ExertSpecific Effects On OligodendrocytesAnd Astrocytes In Vitro

PSM09 Poster Session 9Astrocytes

PSM09-01 Mishra, M.K.In Vivo And In Vitro Modulation OfAstroglial Responses In JapaneseEncephalitis Virus Infection

PSM09-02 Konat, G.W. Phosphodiesterase Genes AreEffectors Of TLR3 And TLR4Signaling In Astrocytes

PSM09-03 Konat, G.W.Profiling Expression Of TLR4Signaling Genes In Astrocytes

PSM09-04 Walls, A.B. One Third Of Glycolytic Activity InAstrocytes Depends On TheOperation Of The Glycogen Shunt

PSM09-05 Cruz, N.F.Restricted Astrocytic Gap JunctionalTransfer Of Hexose-6-Phosphates

PSM09-06 Cho, W. Dual Transgenic Reporter Mice AsA Tool For Monitoring ExpressionOf GFAP

PSM09-07 Yamada, M. BMP Signaling Is Involved In TheControl Of Growth AndDifferentiation Of Glial Cells

PSM09-08 Leal, M.C. Mitogen-Activated Protein KinasePathways Play A Critical Role InHypoxia-Induced Insulin DegradingEnzyme Expression And Activity

PSM09-09 Burkovetskaya, M.E.Characterization Of AstrocyteActivation In Acute Brain Slices FromMice Harboring Brain Abscesses

PSM09-10 Tong, X.Y. Mechanisms Of Astrocyte SwellingFollowing Oxidative Stress

PSM09-11 Karmakar, S.Development Of Guide-CannulaIntracranial Allograft Model OfGlioblastoma In Sprague-Dawley Rats

PSM09-12 Mcguire, S.O. Alterations In Inflammatory MarkersFollowing Treatment With BlueberryPowder

PSM10 Poster Session 10Neuronal-Glial Interactions

PSM10-01 Mishra, M.K.Neuronal-Glia Cross Talk Via TLRSignaling In Japanese Encephalitis

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Rio/Medina/Guadalupe

PSM11 Poster Session 11Late Breaking Abstracts

PSM11-01 Krishnamurthy, K.Ceramide Regulates AtypicalPKC-mediated Cell Polarity inPrimitive Ectoderm Cells

PSM11-02 Chauhan, N.B. ICV Anti-ADDL Antibody PreventedEarly Synaptic Deficits in TGCRND8 Mouse Model of AD

PSM11-03 Nguyen, H.X. Complement proteins overcome myelininhibition of neurite outgrowth

PSM11-04 Frederick, T.J.Combining Immunotherapy withGamma-secretase Inhibition for the Treatment of Established EAE

PSM11-05 Tobin, J.E.Axonal Involvement in Early StageCuprizone Demyelination of Mouse Corpus Callosum

PSM11-06 Mahajan, K. Role of Lipid Rafts/Caveolae in IGF-1Mediated Oligodendrocyte Progenitor Survival

PSM11-07 Ferreira, G.C. Evidence for a Synergistic Action ofGlutaric and 3-Hydroxyglutaric Acids disrupting Rat Brain EnergyMetabolism

PSM11-08 Bruchey, A.K.Behavioral, Physiological andBiochemical Hormetic Responses tothe Autoxidizable Dye Methylene Blue

PSM11-09 Schuck, P.F.Cis-4-Decenoic Acid Acts as anUncoupler of OxidativePhosphorylation and Elicits OxidativeStress in Rat Brain

PSM11-10 (OP06-03)Pathmajeyan, M.S.Influence of Prion Protein Expressionon Glutamate Uptake in PrimaryAstrocytes

PSM10-02 White, A.B. Altered Membrane Architecture:A Model For Neurodegeneration InSphingolipidoses

PSM10-03 Jalabi, W. Endotoxin Preconditioning Of TheCNS: Microglia Activation AndNeuroprotection

PSM10-04 Blutstein, T.Hormonal Modulation Of TheGlutamate-Glutamine Cycle

PSM10-05 Popescu, D.C. Impact Of Akt-ExpressingOligodendrocytes On Neurons

PSM10-06 Hutson, S.M.Is The Anaplerotic Enzyme PyruvateCarboxylase (Pc) Only Expressed InAstrocytes?

PSM10-07 Maciejewski, P.K.A Model For Astrocytic Modulation OfDe Novo Neurotransmitter GlutamateSynthesis In Presynaptic Terminals

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Rio/Medina/Guadalupe

NO PHOTOGRAPHY ALLOWED OF POSTERSAuthors Present

5:45pm—6:45pm Tuesday • 1:30pm—2:30pm Wednesday

PTW01 Poster Session 11Generation of Neurons and Glia

PTW01-01 Jana, M. Transcriptional Up-Regulational OfPLP And MOG Genes In HumanNeurospheres By Gemfibrozil ViaPPAR-Beta

PTW01-02 Yu, S.P.Roles Of Src And ERK1/2 Kinases InNeuronal Differentiation Of CulturedMouse And Human EmbryonicStem Cells

PTW01-03 Loulier, K. Beta 1 Integrin Signaling Is NecessaryFor Anchorage Of Neural ProgenitorsAt The Murine Ventricular Surface

PTW01-04 Jablonska, B. Cyclin-Dependent Kinase 2 Is CriticalFor Proliferation And Self-Renewal OfNeural Progenitors In The AdultSubventricular Zone

PTW01-05 Szele, F. Galectin-3 Modulates PostnatalSubventricular Zone Cell Migration

PTW01-06 Buono, K.D.Murine Neural Precursor Cell FateRegulation By Leukemia InhibitoryFactor

PTW01-07 Li, Y.TrkB-Dependent HippocampalNeurogenesis Governs Sensitivity ToAntidepressive Treatment

PTW01-08 Lang, B.T.Increased Proliferation, But NotSurvival Of The Neural ProgenitorsIn A Rat Model Of Type-2 Diabetes

PTW02 Poster Session 12Neurotransmitters, Receptors &Ion Channels

PTW02-01 Wang, W. Preliminary Study On Activity AndStructure Of Recombinant SerineRacemase From E. Coli

PTW02-02 Berube, P. Synergistic Effects OfDocosahexaenoic Acid On DopamineReceptors D2 Upregulation InducedBy H2O2

PTW02-03 Romanelli, R.J.Localization Of The Dopamine D2Receptor In Lipid Raft Microdomains:Implications For Receptor Function

PTW02-04 Kadapakkam, S.R. Identification Of GlucocorticoidResponse Element In Rat TyrosineHydroxylase Gene

PTW02-05 Lajtha, A. Nicotine Effects In Adolescent Brain

PTW02-06 Lapiz-Bluhm, M.D. Possible Role For 5-HT In RatOrbitofrontal Cortex In TheImpairment Of Reversal LearningInduced By Chronic Cold Stress

PTW02-07 Pickering, D.S. Pharmacological Characterization OfBiarylisopropylalkylsulfonamideAMPA-R Potentiators

PTW02-08 Ogawa, Y. PSD-93 Clusters Kv1 Channels AtAxon Initial Segments IndependentOf Caspr2

PTW02-09 Bomben, V.C. Inhibition Of Transient ReceptorPotential Canonical Channels ArrestsCytokinesis In Human MalignantGlioma Cells

PTW02-10 Santiago-Pérez, L.I. Upregulation Of Alpha7nAChR IsInduced By Chronic Treatment WithHIV-1 Envelope Protein, Gp120 In1321N1 Astrocytoma Cells

PTW03 Poster Session 13Neuroinflammation

PTW03-01 Beck, K.D. Chronic Complement-MediatedInflammation Promotes RecoveryAfter Spinal Cord Injury

PTW03-02 Stokely, M.E.Differential Responses Of InducibleHeat Shock Protein 72 To TreatmentsIn An Early Model Of AutoimmuneOptic Neuritis

PTW03-03 Konat, G.W. Cerebral Inflammatory Response ToPeripheral Viral Challenge

PTW03-04 Samuelsson, M.Glial Dysregulation Of C/EBP In ThePresence Of Alzheimer Aß Peptides

PTW03-05 Cribbs, D.H.The Role Of Peripheral Factors OnAlzheimer's-Like Neuropathology InOlder Amyloid Precursor ProteinTransgenic Mice

PTW03-06 Pettersson, C. NAC And DFO Enhance LPSInduced iNOS Expression In BV-2Cells Through A P38 MAPKDependent Mechanism

PTW03-07 Nichols, J.R.Toll-Like Receptor 2 (TLR2)Deficiency Leads To Increased Th17Infiltrates In Experimental BrainAbscesses

PTW03-08 Esen, N.The Synthetic PPAR-gammaAgonist Ciglitazone AttenuatesNeuroinflammation And AcceleratesEncapsulation In Bacterial BrainAbscesses

PTW03-09 Forsthuber, T.G. Mif Knockout Mice Are MoreSusceptible To Dexamethasone-Induced Apoptosis

PTW03-10 Kauppinen, T.M. PARP-1 Regulates NF-kB ActivityVia SIRT1/Sirtuins

PTW03-11 Larsen, E.C. Micropet Detection Of Zymosan-Induced Microglial Activation In RatWhite Matter

PTW03-12 Zaheer, A. A Novel Role Of Glia MaturationFactor: Induction Of InflammatoryCytokines Cytotoxic ToOligodendrocytes

PTW03-13 Howe, C.L. Immunological Aspects Of AxonalAnd Neuronal Injury In TheDemyelinated CNS

PTW03-14 Smerjac, S.Cytoskeletal Degradation AndOxidation In ExperimentalAutoimmune Encephalomyelitis(EAE)

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Rio/Medina/GuadalupePTW04-02 Nowitzki, K.M.Allograft Inflammatory Factor-1 InThe Microglia Response To MPTPNeurotoxicity

PTW04-03 Hewett, J.A. Microglial Nitric Oxide (NO)Production In Culture Is Regulated ByThe Size Of The Population Of CellsThat Express NO Synthase-2

PTW04-04 Jana, M.IL-12 p40 Homodimer But Not IL-12p70 Induces The Expression Of IL-16In Microglia And Macrophages

PTW04-05 Roy, A.Oxidative Stress Up-RegulatesMicroglial CD11b Via Nitric Oxide

PTW04-06 (OP03-01) Kane, C.J.Microglial Cells And PPAR-GammaAgonists Protect Neurons AgainstEthanol Neurotoxicity

PTW04-07 (OP03-03) Hsieh, C.L.A Requirement for TREM2 Ligands inthe Phagocytosis of Neuronal Cellsby Microglia

PTW05 Poster Session 15Demyelination and Remyelination

PTW05-01 Bieber, A.J.Genetic Determinants Of CNS RepairFollowing Chronic DemyelinationIn Mice

PTW05-02 Kirschner, D.A. A Novel Rapid And QuantitativeAssessment Of Demyelination AndRemyelination In Spinal Cord InjuryModels

PTW05-03 Tiwari-Woodruff, S. Conduction Deficit And Pathology InCorpus Callosum Of EAE AndCuprizone-Induced Demyelinating Mice

PTW05-04 Fogal, B. The Search For Stimulators OfOligodendrocyte Precursor Proliferation

PTW05-05 Pedraza, C.E.Induction Of OligodendrocytePrecursor Differentiation By SmallMolecules

PTW05-06 Khan, M.Plasmalogen Deficiency In CerebralAdrenoleukodystrophy And ItsModulation By Lovastatin

PTW05-07 Gadea, A. Role Of ET-1 On Remyelination OfAcute Demyelinating Lesions In TheSubcortical White Matter

PTW05-08 Vana, A.C. Role Of Cytosolic Phospholipase A2And Lipoxygenase In ExperimentalAutoimmune Encephalomyelitis

PTW05-09 Pannu, R.Expression Of Modulators OfOligodendrocyte Progenitor (OP)Differentiation During Acute AndChronic Cuprizone Demyelination

PTW05-10 Aguirre, A. NG2-Progenitors Are The MainProliferative Cells After CorpusCallosum Demyelination AndGenerate Oligodendrocytes AndAstrocytes

PTW05-11 Warrington, A.E.Methylprednisolone Does Not InhibitAntibody Induced Remyelination

PTW05-12 De Vries, G.H. Didox Ameliorates And ReversesClinical Symptoms EAE

PTW05-13 Jones, R.E. Feasibility Of Telemetric MonitoringOf Physiological Status In Mice WithExperimental AutoimmuneEncephalomyelitis

PTW05-14 Schwartz, R.F. A Clinically Relevant Targeted EAEModel In The Rat

PTW05-15 Millanovich, V.L. Notch Pathway And The Effect OfApotransferrin On Remyelination

PTW05-16 Wright, B.R. Aptamers Selected From MyelinSubstrates Used As Alternatives ToAntibodies To Study, Diagnose AndTreat Demyelinating Diseases

PTW05-17 Aguirre, A. Subventricular Zone GAD65-GFP+Cells Redirect Their MigrationPathway After Corpus CallosumDemyelination

PTW03-15 Murphey, C.Myelin Antigen Transfer In TheCentral Nervous System InExperimental AutoimmuneEncephalomyelitis

PTW03-16 Weinger, J.G. Enhanced Expression Of Soluble AxlAnd Mer Receptor Tyrosine Kinases(RTKs) In Active And Silent MultipleSclerosis (MS) Lesions

PTW03-17 Brahmachari, S.The Expression Of Beta1 But NotAlpha4 Integrin Of VLA4 Is GenderSensitive: Implications For MS

PTW03-18 Xie, X. TLT2 Has Both Constitutive AndInducible Patterns Of Expression InThe Healthy And Inflamed CNS

PTW03-19 Puntambekar, S.S. The Proinflammatory Nature OfPolyamines In CNS Inflammation

PTW03-20 Doose, J.M.Tmem176b, A Biomarker Of RepairResponses Within The CNS?

PTW03-22 Giri, S.Role Of AMP-Activated ProteinKinase In Psychosine Medicated CellDeath In Oligodendrocytes AndInflammation In Astrocytes

PTW03-23 Wilson, E.H. Behaviour Of An Antigen SpecificCD8+ T Cell Population In The BrainDuring Chronic T. gondii Infection

PTW03-24 Perez-Polo, J.R. Inflammatory Outcome After OxygenResuscitation Of P7 Rodents ExposedTo Hypoxia Ischemia

PTW03-25 (OP05-04) Liu, S. MyD88-Dependent Pathways AreImportant For Microglial AndAstrocyte Responses ToCitrobacter Koseri

PTW04 Poster Session 14Microglia

PTW04-01 Austin, S.A. Elevated PLD-Mediated SignalingContributes To The Elevated BasalReactivity Inalpha-Synuclein-/-Microglia

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Rio/Medina/Guadalupe

NO PHOTOGRAPHY ALLOWED OF POSTERSAuthors Present

5:45pm—6:45pm Tuesday • 1:30pm—2:30pm Wednesday

PTW06-08 Kumar, V. Chronic Aluminium Induced ROSGeneration Makes MitochondrialMnsod Susceptible To OxidativeDamage

PTW06-09 Vatassery, G.T. Apolipoprotein E Deficiency ModifiesThe Rate Of Depletion Of AlphaTocopherol (Vitamin E) From MiceBrains

PTW06-10 Sharma, S. Effect Of Oxysterols On IGF-1Signaling And ß-Amyloid ProductionIn Organotypic Slices Of Adult RabbitHippocampus

PTW06-11 Saluja, I. Alteration Of Happswe Metabolism InX11Alpha-Deficient (+/-) Mice

PTW06-12 Sánchez-Iglesias, S. Aluminium Administered OrallyAlters The Activity Of AntioxidantEnzymes And Oxidative Damage:Differences Between Brain Areas

PTW06-13 Kaminska, A. Amyotrophic Lateral Sclerosis (ALS)Is A Progressive NeurodegenerativeDisease Involving SelectiveDegeneration Of Motor Neurons

PTW06-14 Bizzozero, O.A. Lipid Peroxidation Scavengers PreventThe Carbonylation Of CytoskeletalBrain Proteins Induced ByGlutathione Depletion

PTW06-15 Zheng, J. Efficacy Of Hydralazine And OtherCarbonyl Scavengers At PreventingThe Carbonylation Of Brain ProteinsInduced By GSH Depletion

PTW06-16 Abdulhay, S. Novel NO-Chimera For TreatmentOf Depression

PTW06-17 Kalinin, S. Anti-Amyloidogenic Treatments In5xFAD Mice

PTW06-18 Valencia, A.Early Deficits In AKT/PKB SignalingThrough Lipid Rafts In Huntington'sDisease

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PTW05-18 Kumar, S.Oxidative Response In Cuprizone-Induced Demyelination And GrowthFactor-Induced Remyelination In Mice

PTW05-19 Chavakula, V. In Vivo Studies Of MOG-InducedEAE Using VEPs, Diffusion WeightedAnd T2 Imaging

PTW05-20 Wood, M.R. Oligodendrocyte Lineage Cells FromBDNF +/- Mice Exhibit BluntedResponses To Cuprizone

PTW05-21 Ghandour, M.S.Reparation Of Chronic DemyelinationBy Thyroid Hormone Therapy

PTW06 Poster Session 16Neurodegenerative Diseases

PTW06-01 Smith, A.W. Induction Of Calpain And CaspaseCascades In Spinal Cord Tissues OfLewis Rats With The Onset OfAcute EAE

PTW06-02 Zaheer, A.Diminished Inflammatory MediatorExpression In The CNS OfGMF-Deficient Mice In Active AndAdoptive Transfer Models Of EAE

PTW06-03 Hilgart, A.A. Carbonylation Of Major CytoskeletalProteins In Multiple Sclerosis

PTW06-04 Moser, A.B. LC-MSMS Lipid Analysis Of LuxolFast Blue Highlighted Regions InX-Linked AdrenoleukodystrophyBrain Tissue Samples

PTW06-05 Royland, J.E. Thyroid Insufficiency In TheDeveloping Rat Brain:A Genomic Analysis

PTW06-06 Baek, R.C. Comparative Analysis Of Brain LipidsIn Mice, Cats, And Humans WithSandhoff Disease

PTW06-07 Tshala-Katumbay, D. Two-Dimensional Proteomics RevealsGelsolin As A Novel Target OfNeurotoxic Gamma-Diketones

PTW06-19 Shim, D.J. Consequences Of Disrupting TheNF-kB/IkBalpha Autoregulatory LoopOn Neuronal Survival And Function

PTW06-20 Edmond, J. Evidence For Oxidative Stress In TheDeveloping Cerebellum Of The RatAfter Chronic Mild Carbon MonoxideExposure (0.0025% In Air)

PTW06-21 Marini, A.M. Identification Of A Novel MechanismRegulating Brain BDNF Levels:BHLHB2 Controls Promoter 4Activity And Neuronal Excitability

PTW06-22 Morgese, M.G. Cannabinoids NormalizeNeurochemical Imbalances AcrossThe Two Hemispheres OfDyskinetic Rats

PTW06-23 Burns, M.R. Pathogenic Spastin Alters NeuriteMorphology And Inhibits FastAxonal Transport

PTW06-24 Maes, E.G. Clathrin-Coated Vesicle DisassemblyBy Hsc70 And Auxilin Is Limited ByThe Rates Of Hsc70 NucleotideExchange

PTW06-25 Apodaca, J.J. Regulation Of Prion Protein ViaUbiquitin Mediated Degradation

PTW06-26 Cunningham, R.L. Androgens Increase DopaminergicNeurotoxicity Through The PKCDelta Pathway

PTW06-27 Samantaray, S. Spinal Cord Degeneration InMPTP-Induced Parkinsonism InC57Bl/6N Mice And Parkinson'sDisease Patients

PTW06-28 Ghosh, A. Statins Protect DopaminergicNeurons In The Mouse Model OfParkinson's Disease

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Rio/Medina/GuadalupePTW07-04 Fiszer De Plazas, S. Activation Of JNK And p38Mitogen-Activated Protein KinasesIs Critical For Hypoxia-InducedApoptosis In Developing CNS

PTW07-05 Wei, L.Dl-3-N-Butylphthalide Protects AgainstIschemic Neuronal And MitochondrialDamage In Rodents

PTW07-06 Zielke, H.R. Oxidative Metabolism Measured ByMicrodialysis In A 7 Day Old RatHypoxia-Ischemia Model

PTW07-07 Fiskum, G.Loss Of Mitochondrial NAD(H)During Neuronal Anoxia AndReoxygenation And After NeonatalHypoxic Ischemia

PTW07-08 Jayakumar, A.R. Ion Transporting Systems In TheMechanism Of Astrocyte SwellingAfter Trauma

PTW07-09 Bertone Uña, A.L. Oligodendroglial Cells Submitted ToHypoxia Are Less Vulnerable ToDamage In The Presence OfIntracellular Iron Chelatorsi

PTW07-10 Adibhatla, R.M. Neuroinflammation AndAnti-Proliferative Effects ModulatedThrough Lipid Metabolism In Stroke

PTW07 Poster Session 17Ischemia and TraumaticBrain Injury

PTW07-01 Schafer, D.P. The Polarized Axonal CytoskeletonDuring Neurodegeneration

PTW07-02 Gillani, R.L. An Analysis Of Dendritic Plasticity InThe Hippocampus Of Aged RatsFollowing Stroke And Treatment WithAnti-Nogo-A Immunotherapy

PTW07-03 Kapadia, R.S. Role Of C/EBP Beta In MediatingPost-Ischemic Inflammation AndNeurogenesis

NO PHOTOGRAPHY ALLOWED OF POSTERSAuthors Present

5:45pm—6:45pm Tuesday • 1:30pm—2:30pm Wednesday

37th Annual Meeting—San AntonioPosters

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Rena Baek, Chestnut Hill, Massachusetts, USATamara Blutstein, Baltimore, Maryland. USA

Woosung Cho, Madison, Wisconsin, USARochelle Coelho, Richmond, Virginia, USA

Gustavo da Costa Ferreira, Porto Alegre, Rio Grande do Sul, BrazilTamar Eviatar-Ribak, PhD, Vermillion, South Dakota, USAChristopher Gregg, PhD, Cambridge, Massachusetts, USA

Ramya Kapadia, Madison, Wisconsin, USAMichael Kiebish, Chestnut Hill, Massachusetts, USA

Kelly Levano, Staten Island, New York, USAYun Li, Dallas, Texas, USA

Shuliang Liu, Little Rock, Arkansas, USAJungsoo Min, Newark, New Jersey, USA

Pablo Paez, PhD, Los Angeles, California, USABruno Pereira, Little Rock, Arkansas, USA

Kimberly Petro, Hershey, Pennsylvania, USASudarshn Purkayastha, New York, New York, USA

William Renthal, Dallas, Texas, USADorothy Schafer, Farmington, Connecticut, USA

Patricia Schuck, Porto Alegre, Rio Grande do Sul, BrazilSeema Shroff, Richmond, Virginia, USA

William Tyler, PhD, Newark, New Jersey, USAJihong Xu, PhD, Little Rock, Arkansas, USA

A special thank you to the International Sociey for Neurochemistryfor their support and generous contribution to the YIEE Awards.

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27

40th Annual ASN Meeting

First Call forSession Proposals

Charleston, SC — March 7-11, 2009The 40th annual meeting of the American Society for Neurochemistry (ASN) will be held inCharleston, South Carolina from March 7-11, 2009. The program committee invites you tosubmit proposals for symposia, colloquia and informal workshops.

The ASN program has traditionally encompassed 4 broad themes:

1) Building the Nervous System

2) Glial Function in Health and Disease

3) Cellular Metabolism and Neurotransmission

4) Neurodegeneration

The program committee encourages proposals from younger investigators, and recommends thatsenior investigators consider having a junior investigator as a co-organizer. Both ASN membersand non-members are invited to submit proposals.

Details for submitting session proposals can be found at:http://www.asneurochem.org/ASN2009Proposals.htmQuestions and inquiries about session topics and session formats can be directed to Vittorio [email protected]

The deadline for session proposals is April 1, 2008.

Examples of ASN symposia, colloquia and workshops from the 2004-2007 annual ASN meetingscan be found on the ASN website: http://www.asneurochem.org/library/meetings.htm

Submissions for Sessions Should Include:1) The Chairperson (and when appropriate co-chair) name, title, affiliation, address,

email and phone number.

2) The title and type of session being proposed.

3) Description (up to 250 words) including a brief scientific background, the current state of thetopic, and why the session would be of high interest to Neuroscientists.

4) A list of speakers, their tentative talk titles, a list of 2 or 3 recent publications, and whetherthey have agreed to participate. Please note that the organizer of a session is not requiredto present.

The Deadline for Proposal Submission is April 1, 2008

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Bernard Haber Award Committee

Nicolas Bazan; (Chair) 2004-2008Bernie Agranoff; 2004-2008Beatrice Capputo; 2004-2008Lou Sokoloff; 2004-2008

Committee for the Advancement &Encouragement of Neurochemistry inLatin America (CAENLA)

Juana Pasquini, Argentina; (Chair); 2007-2011Mike Collins; Cuba/USA; 2004-2008 Guillermina Almazan; Canada; 2004-2008Robin Miskimins, USA; 2006-2010Marta Antonelli; Argentina; 2004-2008

Electronic Communication Committee

Eric Klann (Chair); 2004-2008Paula Dore-Duffy; 2004-2008Steve Carroll; 2004-2008Sean Liour; 2004-2008

Finance Committee

Jean Merrill (Treasurer)Paula Dore-Duffy (Co-Chair)Wendy MacklinDavid ShineMonica CarsonBruce TrappGeorge DeVries

Jordi Folch-Pi Award Committee

Brian Popko (Chair); 2006-2010Eric Murphey (Co-Chair); 2008-2012Colin Combs; 2008-2012Inderjit Singh; 2006-2010Sandra Hewett; 2006-2010Robert Zand; 2004-2008

Marian Kies Award Committee

Regina Armstrong (Co-Chair); 2007-2011G. Jean Harry (Co-Chair); 2007-2011Tika Beneviste; 2004-2008Patrizia Casaccia-Bonnefil; 2004-2008Rick Dobrowsky; 2006-2010

Membership Committee

James Connor (Chair); 2004-2008Naser Muja; 2004-2008Sara Becker-Catania; 2006-2010Vlad Parpura; 2006-2010Neelima Chauhan; 2004-2008

Nominating CommitteeJudy Grinspan (Chair); 2007-2011Peter Baas; 2006-2010Scott Brady; 2006-2010

Presidential Advisory CommitteePam Knapp (Chair); 2004-2008Itzhak Fischer; 2006-2010Matt Rasband; 2006-2010Rashmi Bansal; 2006-2010Ed Hall; 2004-2008Peter Stys; 2006-2010Tim Coetzee; 2004-2008Gary Landreth; 2006-2010Terri Wood; 2004-2008Cinzia Della Russo; 2004-2008Jean Merrill; 2004-2008

Public Policy and Education CommitteeSandra Hewett (Chair); 2006-2010Monica Carson; 2006-2010Tammy Kielian; 2006-2010Mike Aschner; 2004-2008Vittorio Gallo; 2006-2010Rashmi Bansal; 2004-2008Jean Harry; 2006-2010

Standing Rules CommitteeCara-Lynne Schengrund (Chair); 2004-2008Jun Yoshino; 2004-2008Arrel Toews; 2006-2010Patty Wight; 2006-2010Martha Stokely; 2004-2008Gibson Wood; 2004-2008

Young Investigator EducationEnhancement Committee Susan McGuire (Chair); 2006-2010 Gary Landreth; 2006-2010Mary McKenna; 2006-2010Babette Fuss; 2006-2010

2009 Charleston SC

Program CommitteeVittorio Gallo (Chair) Regina ArmstrongMonica CarsonJohn CorbinBabette FussPhil HaydonPam KnappSteve LevisonHarry SontheimerFlora VaccarinoKaren WilcoxTerri Wood

Local Host CommitteeSwapan Ray, ChairNarin BanikNarayan BhatPierre GiglioAzizul HaqueEdward HoganJames KrauseMitzi NagarkattiPrakash NagarkattiKumar SambamurtiInderjit SinghWilliam TyorLing WeiJohn WoodwardShan Yu

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ASN Committees

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Hyatt Meeting/Exhibit Space

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A TOTAL APPROACH TO DISEASE MANAGEMENT

At Teva Neuroscience, our inspiration to achieve comes from knowing we help people who live with neurological diseases.

today we are expanding our reach with a vision to be the North American leader in neurology through the quality of our people, our products, and our focus on the patient. Each has a critical role, but the patient is at the center of everything we do.We are committed — through our own research and by supporting other organizations — to continue to improve

Quality People Quality Products Patient Focus

1-800-221-4026www.tevaneuroscience.com

1-800-887-8100www.sharedsolutions.com

1-877-429-4532www.parkinsonshealth.com