alzheimers: a mini hack
TRANSCRIPT
‘Alzhack’
@ Py-Data 4th August, 2015
Frank Kelly Data Scientist [email protected]
Maia Smith Bioinformatics Trainee [email protected]
Dave Coulthard Data Scientist [email protected]
in 2014, it was estimated that more than 44m people worldwide were suffering from dementia. By 2050 that
number is expected to triple.
http://www.economist.com/news/science-and-technology/21607761-tests-alzheimers-are-improving-treatment-still-some-way-recherche-du
Ft.com
We are using data with the aim of performing
early diagnosis of
Alzheimer’s disease
HOW ?
Data
emails written by one woman
affected with Alzheimer’sto a single recipient,
frombefore disease onset
to the end of her email career.
5:30 PM 6 PM6:30 PM
Data: Example
“You must be THE most DEEEVINE granddaughter in the WHOLE WORLD!!! Thank you !!Thank you !!Thank YOU!!!!”
“THANK YOU!!!!!! !THANK YOU!!!! THANK YOU!!!!!! FROM THE BOTTOM OF MY HEART ETC. ETC.ETC. YOU ARE A REAL SWEETHEART!!! XXXXXXX”
“to the clock fairy!!!!............. Thank you!!! thank you!!!! thank you!!!!!from the bottom of my heart and everyone elses'bottom, TOOO!!!!!!”
Method - metrics
We extracted: age at time of sending,
time of email, time between emailsnumber of responses in email thread,
readability metrics, sentiment analysis, location of recipient,
repetition
Analysis
Noisy data!time series analysis changepoint detection (ramp)
to detect a decline in lucidity
Results
Results
a series of recipes
forgot she had
already replied
“...I responded to your email during
the night and wasn't thinking all that
clearly and on rereading, just wanted
to submit an addenda…”
Recipient’s Location:
Next steps
An email plugin !We need more people
more emails (and other) data Alzheimer’s-specific metrics
Domain specific knowledge...get in touch...
Thank you!
...contact one of us if you want to helpdevelopment / data sci / domain-specific
or just have an idea!
Frank Kelly Data Scientist [email protected] / @norhustla
Maia Smith Bioinformatics Trainee [email protected]
Dave Coulthard Data Scientist [email protected]
