almac overview
TRANSCRIPT
www.almacgroup.com
Almac
Overview
2
Welcome to Almac…
3
Who is Almac?
Almac is a world leading drug
development & commercial services company; providing an
expanding array of innovative
solutions worldwide across the drug development lifecycle
4
Our Vision Statement
“Almac will be the leader
in the generation of
superior solutions for the
advancement of human
health”
5
Almac: An Integrated Group
6
Milestones
7
Background
Founded in 1968
Global Headquarters in Craigavon, Northern Ireland
Turnover $0.5 billion+ (CMO market est. approx. $14bn)
~ 4,000+ Personnel Globally
Unique ownership- charitable foundation: McClay Foundation
All Profit Re-invested
8
Our Global Presence
DEPOTS ON60 6CONTINENTS
SHIPMENTS ANNUALLY
TO OVER COUNTRIES80
Facilities with 4,000+ personnel
in:
• Europe : Northern Ireland,
Republic of Ireland, Scotland,
England
• US: Pennsylvania, North
Carolina, California
• Asia: Japan, Singapore
To over 80 countries
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Diverse Customer Base
33%
10%
10%
29%
6%
5%
4%
2%
Pharma - Large
Pharma - Medium
Pharma - Small
Biotech
CRO
Academia
Other
Speciality
Diagnostics
1%
Diverse client base across the Group assuring stability
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Overview of Almac’s market position
Clinical
ServicesClinical
TechnologiesPharma
ServicesSciences Diagnostics
Top 3 service
provider for
clinical supply
services globally
Industry leader
– top 5 globally
Smaller player,
well known for
solid oral dose
capabilities
Smaller player,
broad range of
service offerings
supported by
excellent science
Almac Group
Smaller player,
more niche
offering
A unique range of services and solutions and a wide range of competitors
(depending on which area of the business you look at)
+ Galen (branded pharmaceuticals) and Discovery (R&D)
11
Discovery Pipeline
The Almac Group provides all of the services
required to take a new drug or compound from
concept right through to final patient delivery.
“World Class Pharmaceutical Solutions”
Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
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Services/Solutions
• Clinical Packaging
• Distribution
• Storage
• Blinding
• Commercial drug
procurement
• Supply chain
management
PHARMA
SERVICES
CLINICAL
TECHNOLOGIES
DIAGNOSTICS
& BIOMARKERS
CLINICAL
SERVICESSCIENCES
• Interactive response
technology (IRT)
• Electronic patient
reported outcomes
• Bio statistical
services
• Pharmaceutical
development
• Commercial
manufacturing
• Commercial
Packaging
• Product launch,
distribution and
other commercial
services
• API services
• Chemical
development
• Analytical services
• Solid state services
• Biocatalysis
• Peptides
• Internal diagnostic
development
• Biomarker
discovery
• Companion
diagnostics
development
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Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
14
Discovery
• A project generator for highly novel oncology programmes
for the pharmaceutical companies.
• It operates in the discovery to preclinical space and
provides Phase I ready programmes.
• Exceptionally, it may chose to take a programme into
Phase I Clinical Trials
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Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
17
Diagnostics
• Microarray based Cancer Diagnostics Company
• Develops, markets and supplies:– Leading edge genomic
expression services
– Products that will radically improve the diagnosis and treatment of cancer
18
Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
19
Sciences
• API Supply
– Synthesis design
– Peptide API
• Drug Product
– Clinical manufacture
– Scale up
• Analytical Services
– Stability
– Release and comparator testing
–Method development
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Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
21
Clinical Services
• Clinical Supplies management
company
• Covers complete supply chain
for Clinical Trials:– blinding
– packaging
– global distribution
– consulting/project management
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Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
Clinical Technologies
Supported
nearly
2 millionpatients
Worked
with
18/20 top
biopharma
companies Renowned
biostats
staffConducted
trials in
60languages
Managed
2000+ clinical
studies to
date
Global
trials
conducted
across 85countries
Interactive Response Technology -
IXRS
Patient Randomization & Blind Protection
Product Inventory Management
Patient Tracking & Status
Study Management Data Availability
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Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
27
Pharma Services
Formulation Development
• - from API to tablet
Commercial Manufacture & Packaging
Distribution & Logistics
• - global distribution
• - inventory management (TROPOS)
• - 3PL & POP
• - late stage customisation
28
Discovery
Discovery R & D
Development
Process
Development
/ Scale Up
Formulation
Development
Clinical
Trials
Delivery
Manufacturing
& Packaging
Sales &
Marketing
29
Galen
• Galen promotes branded and generic prescriptionmedicines in the UK & Ireland e.g.– Calceos (for osteoporosis)
– Laxido Orange (for chronic constipation)
– Flotros (for overactive bladder)
– Penthrox (Analgesic) Launched Jan 2016
• Trustsaver Portfolio
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Commercialisation – Galen
• Galen Ltd
• Recognised Speciality Pharmaceutical Company
• Products Sold into 23 Countries
• Successful Entrance into US Market in 2012
• Therapy Areas include:
• Oncology
• Gastroenterology
• Female Health
• Pain Management
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The Future
• We are a global player and we will continue to
increase our presence throughout the world.
• We will continue to develop new technologies,
new medical interventions and new markets.
• We will achieve our vision.