allan rozenberg, phd - dynamic chiropractic · only 10 weeks of far infrared sauna therapy9 figure...

13
© 2015 Wearable Wellness, Inc. Page 1 THE WELLNESS BENEFITS OF VIVIRS IMMERSIVE FAR INFRARED THERAPY Allan Rozenberg, PhD Allan Rozenberg, PhD, founder and Chief Technology Officer of Wearable Wellness, Inc., is a biomedical engineer with over two decades of experience in the research, development, and commercialization of diagnostic and therapeutic products. The holder of over 20 patents, Dr. Rozenberg has a strong background in both science and engineering. He has done extensive work in the area of heating and cooling of human tissue and served as COO of BeneChill, Inc. for seven years. He holds a doctorate in Biomedical Engineering from the University of Minnesota; and a masters in Health Informatics.

Upload: others

Post on 26-Jun-2020

1 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 1

THE WELLNESS BENEFITS OF VIVIR’S

IMMERSIVE FAR INFRARED THERAPY

Allan Rozenberg, PhD

Allan Rozenberg, PhD, founder and Chief Technology Officer of Wearable Wellness, Inc., is a biomedical

engineer with over two decades of experience in the research, development, and commercialization of

diagnostic and therapeutic products. The holder of over 20 patents, Dr. Rozenberg has a strong

background in both science and engineering. He has done extensive work in the area of heating and

cooling of human tissue and served as COO of BeneChill, Inc. for seven years. He holds a doctorate in

Biomedical Engineering from the University of Minnesota; and a masters in Health Informatics.

Page 2: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 2

Introduction Whether one calls it hamman, bania, mushi-buro, temescal, sweat lodge, sauna, or infrared body wrap,

immersive heating has been used by many civilizations for centuries. People around the world have

recognized the health benefits of a good sweat1,2. Thankfully, modern technology is making it easier and

safer for everyone to take advantage of this ancient method of wellness. The health benefits of dry

immersive hyperthermia like the far infrared heating delivered by Vivir are well documented in the

scientific literature; they include weight loss, detoxification, cardiovascular health as well as pain relief

and symptom reduction for conditions such as fibromyalgia, arthritis, and chronic fatigue syndrome.

This white paper will give examples of some of the current research and findings that support the use of

frequent immersive far infrared therapy, like that which is delivered by wearing Vivir, as part of a

healthy lifestyle. It will show that repeated thermal therapy help people in the following ways

lose weight and lowers body mass index

helps the body remove dangerous toxins that are stored in tissue

reduces rheumatoid pain

improves symptoms of chronic fatigue syndrome

benefits cardiovascular health

Far Infrared Radiation (FIR) Infrared light is invisible radiant energy with longer wavelengths than those of visible light, specifically

from the nominal red edge of the visible spectrum at 0.7 microns up to 1000 microns. Far infrared is

that portion of the spectrum from 3 to 1000 microns. The natural resonant frequencies of molecules of

water and organic substances are within 5 to 15 microns which is within the far-infrared spectrum;

therefore, water and organic substances absorb energy easily from FIR radiation.

Page 3: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 3

Figure 1 Electromagnetic Spectrum

The heat that warms our body when we are in direct sunlight is infrared radiant energy. This energy can

warm us even when it’s cold outside because infrared radiation is better at warming our bodies than it is

at warming the air around us.

Our bodies also radiate far infrared energy through the skin at 3 to 50 microns, with most output at 9.4

microns3. Our palms emit FIR energy also, between 8 and 14 microns. This is the energy that is used in

alternative palm healing techniques such as the eastern medicine practices of Qiqong or Reiki4. Vivir is

tuned to emit FIR radiant heating in the same range.

The most common medical use of FIR heating is neonatal warmers used in hospital newborn nurseries5.

Many hospitals now use FIR radiant heating panels in the ceilings of patient rooms due to its safe and

efficient heating of the patient6. These panels are very efficient at heating the patient without heating

the air in the room. This is because the far infrared heat generated by these panels is radiant heat as

opposed to convective heat.

Far infrared radiation has become very popular in the sauna industry because of its ability to heat the

person in the sauna without heating the air. This makes the sauna experience more comfortable for the

user since the air being breathed is not uncomfortably hot. It is also more energy efficient than

traditionally heated saunas making them better for in-home use, where power may be limited. Vivir’s

heating is similar to the heating delivered by the popular far infrared saunas, delivering FIR in similar

wavelengths without the need to be stationary inside a sauna. Vivir’s combination of increased

metabolism due to activity and FIR immersion may yield enhanced results to those achieved via FIR

sauna.

Page 4: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 4

Weight loss It is commonly understood that the act of sweating will reduce body weight. While a majority of this

weight is water loss that is replenished quickly by rehydration, there is much more to the process. It is

not as simple as water leaking out of a sponge. Sweating is a complex function and involves millions of

glands that produce sweat to cool the body through evaporation. Those glands consume energy while

secreting sweat but that is only a fraction of the energy consumed from whole body hyperthermia. The

body’s thermoregulatory process involves heart rate, cardiac output, and metabolism, all of which

consume calories7. Sweating from heat conditioned infrared therapy users can approach the rate of 2

liters (approximately 2000 grams) per hour of use15.

Basal metabolic rate (BMR), the rate that the body burns calories when at rest, is enormously affected

by body temperature. In metabolic studies of patients with fever, their metabolic rate increased by 7%

for each 0.5ºC8. Body temperature can easily rise 1ºC in a 45 minute far infrared heating session as

delivered by Vivir which increases the calories burned by 15% without any exercise.

Numerous studies have shown that repeated whole body hyperthermia sessions like those delivered by

Vivir can lead to weight loss. Biro, et al, studied 10 obese subjects that participated in daily far infrared

sauna therapy sessions. The body weight of these subjects significantly decreased after only 2 weeks.

They also discussed a patient who was unable to exercise due to osteoarthritis who lost 38 pounds after

only 10 weeks of far infrared sauna therapy9

Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects after 2-week sauna therapy (*P<0.05).

Pilch, et al, saw a significant reduction in the body mass index of 20 healthy female volunteers after only

7 sauna treatments that were done every other day10. They discovered that the subjects not only had a

drop in total cholesterol levels but an increase in high density lipids (HDL) which is the “good

Page 5: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 5

cholesterol”. This demonstrates that immersive heat has a healthy effect on the body’s metabolism of

certain fats and has the same effect as moderate exercise in fat metabolism11.

In a study looking at infrared therapy in patients with coronary risk factors, Imamura, et al saw a

statistically significant reduction in weight in subjects undergoing the thermal therapy compared to

controls after only 2 weeks.12

Beever et al. studied 20 patients with type 2 diabetes. The patients received 20 minute FIR sauna

sessions three times per week for 3 months. The researchers found significant improvements in systolic

blood pressure and a trend toward decreased waist circumference.13 They concluded that thermal

therapy like that which is delivered by Vivir is an attractive lifestyle option for type 2 diabetes patients.

Detoxification Toxins are poisonous substances that when exposed to our bodies can cause injury or disease. These

harmful materials are all around us and are increasingly becoming more common in the environment

our modern lifestyles. Some toxins, such as antibiotics and chemotherapy are medically useful, but can

have harmful side effects to us after they have done their good. Safe removal of these substances from

our bodies will improve our total wellness. Immersive FIR therapy as delivered by Vivir can be an

effective way to detoxify.

Some of the most common toxins in our environment are the heavy metals: arsenic, cadmium, lead and

mercury. All four of these elements are confirmed or probable carcinogens and have wide ranging toxic

effects on humans. Several studies have shown that these elements are excreted by sweat glands in

relatively high concentrations compared to plasma levels14. This shows that sweating is an important

pathway to removing these toxins from our bodies. Regular sauna users can expect to secrete 2 liters

per hour which can carry with it a significant amount of toxins15.

One of the major challenges in detoxification is the lipophilicity (affinity for fat tissues) of many of these

compounds. These lipophilic compounds remain in the body for very long periods of time and therefore

continue to accumulate in the fatty tissue. Some of the compounds that tend to bioaccumulate are

polychlorinated biphenyls, polybrominated biphenyls, PCP and THC16. These compounds have been

associated with, fatigue, muscle weakness, nervousness, joint pain, headache, immune dysfunction, skin

abnormalities, abdominal pain, eye irritation, cancer, and death17. Mobilizing these fat stores is the best

way to remove these toxins from the body18. It has been shown that forced sweating and exercise can

mobilize the fat and release these toxins19.

In a study of police officers who were exposed to toxins from methamphetamine labs in Utah, Ross and

Sternquist showed that repeated sauna treatments helped improve the health and brain function of

these officers.20 Dahlgren, et al, studies workers who were exposed to toxins during rescue operations

following the 9/11 World Trade Center attack. Blood samples of these workers were taken before and

after they enrolled in a detoxification treatment regimen that was developed by Hubbard.21 This 3-week

regimen included exercise, thermal therapy and vitamin and mineral supplements. The blood samples

Page 6: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 6

showed reductions in toxins in these subjects. The study also reported a large reduction in symptoms

reported by these subjects.

Figure 3 Symptoms before and after sauna treatment regimen in post 9/11 rescue workers

Pain relief The use of heat for pain relief has a very long history. It is commonly used to treat muscle pain in sports

medicine as well as in physical therapy. FIR heating as delivered by Vivir is the safest and most efficient

way to heat the tissue for reasons explained earlier. Immersive far infrared therapy is especially useful

for non-localized pain, such as fibromyalgia, osteoarthritis, or chronic fatigue syndrome.

Masuda et al performed a controlled trial of immersive far infrared therapy on 44 patients with chronic

pain. The patients were split into two groups: Group A (n=24) was treated with cognitive behavioral

therapy, rehabilitation and exercise therapy. Group B (n=22) was treated with the same therapy as

group A but also included far infrared thermal therapy once per day for 4 weeks. Both groups had

improvements in pain and anger scores but the group with infrared therapy had significantly more

improvement. 22

Fibromyalgia is a chronic disorder that is characterized by widespread pain and accompanied by fatigue,

sleep, memory and mood issues. The cause is unknown and there is no cure. Current medications that

include pain relievers, antidepressants, and anti-seizure drugs are not very effective. In a study of 44

female fibromyalgia patients, Matsumoto et al, found that a 12 week thermal therapy program that

included sauna therapy once daily for 3 days/week, all patients reported significant reductions in pain

and symptoms.23

Page 7: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 7

There has been some evidence that FIR therapy can improved the symptoms of chronic fatigue

syndrome. Masuda et al studied two patients with chronic fatigue syndrome who had failed to get any

relief using prednisolone. The patients underwent FIR thermal therapy similar to that delivered by Vivir

once or twice a week, for a total of 35 sessions. These patients had dramatic improvements in their

symptoms including fatigue, pain, sleep disturbances and low-grade fever after 15 to 25 sessions.24

Figure 4 Clinical course of one patient with chronic fatigue syndrome.

Page 8: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 8

Cardiovascular It is a common understanding that applying heat to tissue will increase blood flow to that tissue by

dilation of the blood vessels. But recently, it has been reported that repeated FIR thermal therapy,

similar to that delivered by Vivir, can improve the hemodynamics and clinical symptoms in patients with

chronic heart failure.25 The mechanism of action for this is thought to be that repeated FIR therapy

increases endothelial nitric oxide synthase (eNOS) production, which leads to better functioning blood

vessels.26,27

Repeated FIR thermal therapy has also been shown to improve myocardial perfusion in patients with

coronary artery-related ischemia. Sobajima et al studied 24 patients with chronic total occlusion of

coronary arteries. Sixteen of the patients received FIR thermal therapy (Waon) daily for three weeks

and the 8 control patients did not. After the three weeks myocardial perfusion scores in the treated

group improved while the non-treated group stayed the same.28

Figure 5 Improvement in myocardial perfusion scores after 3 weeks of FIR thermal therapy.

Conclusion This is only a sampling of studies that show the health and wellness benefits of immersive far infrared

thermal therapy like that which is delivered by wearing Vivir. There are many more studies documented

in our bibliography and elsewhere, and the impressive results have led to many new studies that are

currently ongoing. It is quite clear that there is a preponderance of data that proves that immersive FIR

as delivered by Vivir should be a part of nearly everyone’s healthy lifestyle.

Page 9: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 9

Bibliography

Arai, Nobuyuki, et al. "Utility of full-body thermotherapy for an elderly patient with multiple organ complications requiring lower-leg amputation." Jpn J Compr Rehabil Sci 5 (2014): 61-65.

Beever, Richard. "The effects of repeated thermal therapy on quality of life in patients with type II diabetes mellitus." The Journal of Alternative and Complementary Medicine 16.6 (2010): 677-681. Blum, Nava, and Arnon Blum. "Beneficial effects of sauna bathing for heart failure patients." Experimental & Clinical Cardiology 12.1 (2007): 29.

Crinnion, Walter J. "Sauna as a valuable clinical tool for cardiovascular, autoimmune, toxicant-induced and other chronic health problems." Alternative medicine review: a journal of clinical therapeutic 16.3 (2011): 215-225. Dahlgren, James, et al. "Persistent organic pollutants in 9/11 world trade center rescue workers: reduction following detoxification." Chemosphere 69.8 (2007): 1320-1325. Dean, Ward. "Effect of Sweating." JAMA 246.6 (1981): 623-623. Fujita, Shoji, et al. "Effect of Waon therapy on oxidative stress in chronic heart failure." Circulation journal: official journal of the Japanese Circulation Society 75.2 (2010): 348-356. Genuis, Stephen J., et al. "Blood, urine, and sweat (BUS) study: monitoring and elimination of bioaccumulated toxic elements." Archives of environmental contamination and toxicology 61.2 (2011): 344-357.

Genuis, Stephen J., et al. "Clinical detoxification: elimination of persistent toxicants from the human body." The Scientific World Journal 2013 (2013). Genuis, Stephen J., Sanjay Beesoon, and Detlef Birkholz. "Biomonitoring and Elimination of Perfluorinated Compounds and Polychlorinated Biphenyls through Perspiration: Blood, Urine, and Sweat Study." ISRN toxicology 2013 (2013). Gutierrez, E., and R. Vazquez. "Heat in the treatment of patients with anorexia nervosa." Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity 6.1 (2001): 49-52.

Hall, John E. "Guyton and Hall Textbook of Medical Physiology." Hannuksela, Minna L., and Samer Ellahham. "Benefits and risks of sauna bathing." The American journal of medicine 110.2 (2001): 118-126. Hsu, Yung-Ho, et al. "Far-infrared therapy induces the nuclear translocation of PLZF which inhibits VEGF-induced proliferation in human umbilical vein endothelial cells." PloS one 7.1 (2012): e30674. Hu, Ko-Hsin, and Wen-Tyng Li. "Clinical effects of far-infrared therapy in patients with allergic rhinitis." Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE. IEEE, 2007.

Page 10: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 10

Iiyama, Junichi, et al. "Effects of single low-temperature sauna bathing in patients with severe motor and intellectual disabilities." International journal of biometeorology 52.6 (2008): 431-437.

Ikeda, Yoshiyuki, et al. "Repeated sauna therapy increases arterial endothelial nitric oxide synthase expression and nitric oxide production in cardiomyopathic hamsters." Circ J 69.6 (2005): 722-9. Kihara T, Biro S, Ikeda Y, Fukudone T, Shinsato T, Masuda A, et al. Effects of repeated sauna treatment on ventricular arrhythmias in patients with chronic heart failure. Circ J. 2004;68(12):1146–51. Kihara, Takashi, et al. "Effects of repeated sauna treatment on ventricular arrhythmias in patients with chronic heart failure." Circ J 68.12 (2004): 1146-1151. Kihara, Takashi, et al. "Waon therapy improves the prognosis of patients with chronic heart failure." Journal of cardiology 53.2 (2009): 214-218.

Kuwahata, So, et al. "Improvement of autonomic nervous activity by Waon therapy in patients with chronic heart failure." Journal of cardiology 57.1 (2011): 100-106. Lee, Chae Hyeong, et al. "A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of a far infrared-emitting sericite belt in patients with primary dysmenorrhea." Complementary Therapies in Medicine 19.4 (2011): 187-193. Leung, Ting-Kai, et al. "Effects of far infrared rays irradiated from ceramic material (bioceramic) on psychological stress-conditioned elevated heart rate, blood pressure, and oxidative stress-suppressed cardiac contractility." Chinese Journal of Physiology 55.5 (2012): 323-330.

Lin, Chih-Ching, et al. "Far infrared therapy inhibits vascular endothelial inflammation via the induction of heme oxygenase-1." Arteriosclerosis, thrombosis, and vascular biology 28.4 (2008): 739-745. Lin, Chih-Ching, et al. "Far-infrared therapy: a novel treatment to improve access blood flow and unassisted patency of arteriovenous fistula in hemodialysis patients." Journal of the American Society of Nephrology 18.3 (2007): 985-992.

Masuda A, Kihara T, Fukudome T, Shinsato T, Minagoe S, Tei C. The effects of repeated thermal therapy for two patients with chronic fatigue syndrome. Masuda, Akinori, et al. "Repeated Sauna Therapy Reduces Urinary 8-Epi-Prostaglandin F2. ALPHA." Japanese heart journal 45.2 (2004): 297-303. Masuda, Akinori, et al. "The effects of repeated thermal therapy for patients with chronic pain." Psychotherapy and psychosomatics 74.5 (2005): 288-294. Matsushita, Kakushi, Akinori Masuda, and Chuwa Tei. "Efficacy of Waon therapy for fibromyalgia." Intern Med 47.16 (2008): 1473-1476. Miyamoto, Hiromitsu, et al. "Safety and efficacy of repeated sauna bathing in patients with chronic systolic heart failure: a preliminary report." Journal of cardiac failure 11.6 (2005): 432-436. Howenstine, James. "New ideas about the cause, spread and therapy of Lyme disease." TOWNSEND LETTER FOR DOCTORS AND PATIENTS. (2004): 64-67.

Page 11: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 11

Miyata, Masaaki, and Chuwa Tei. "Waon therapy for cardiovascular disease: innovative therapy for the 21st century." Circulation journal: official journal of the Japanese Circulation Society 74.4 (2010): 617-621.

Miyata, Masaaki, and Chuwa Tei. "Waon therapy for cardiovascular disease: innovative therapy for the 21st century." Circulation journal: official journal of the Japanese Circulation Society 74.4 (2010): 617-621. Miyata, Masaaki, et al. "Beneficial effects of Waon therapy on patients with chronic heart failure: Results of a prospective multicenter study." Journal of cardiology 52.2 (2008): 79-85.

Nurmikko T, Hietaharju A. Effect of exposure to sauna heat on neuropathic and rheumatoid pain. Pain. 1992; 49:43–51. Rau, Cheng‐Shyuan, et al. "Far‐Infrared Radiation Promotes Angiogenesis in Human Microvascular Endothelial Cells via Extracellular Signal‐Regulated Kinase Activation." Photochemistry and photobiology 87.2 (2011): 441-446.

Rogers, Sherry A. Detoxify or die. Sand Key Company, 2002. Sobajima, Mitsuo, et al. "Repeated sauna therapy attenuates ventricular remodeling after myocardial infarction in rats by increasing coronary vascularity of noninfarcted myocardium." American Journal of Physiology-Heart and Circulatory Physiology 301.2 (2011): H548-H554. Tei, Chuwa, et al. "Waon therapy improves peripheral arterial disease." Journal of the American College of Cardiology 50.22 (2007): 2169-2171. Tu, Yuan-Po, et al. "Postconditioning with far-infrared irradiation increases heme oxygenase-1 expression and protects against ischemia/reperfusion injury in rat testis." Life sciences 92.1 (2013): 35-41. Umehara, Megumi, et al. "Repeated Waon therapy improves pulmonary hypertension during exercise in patients with severe chronic obstructive pulmonary disease." Journal of cardiology 51.2 (2008): 106-113. Vatansever, Fatma, and Michael R. Hamblin. "Far infrared radiation (FIR): Its biological effects and medical applications." Photonics and Lasers in Medicine 1.4 (2012): 255-266.

Yu, Shi‐Yau, et al. "Biological effect of far‐infrared therapy on increasing skin microcirculation in rats." Photodermatology, photoimmunology & photomedicine 22.2 (2006): 78-86.

Page 12: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 12

References 1 Aaland, Mikkel. Sweat: The Illustrated History and Description of the Finnish Sauna, Russian Bania,

Islamic Hammam, Japanese Mushi-buro, Mexican Temescal, and American Indian & Eskimo Sweat Lodge. Capra Press, 1978. 2 Nordskog, Michael, Aaron W. Hautala, and David Salmela. The Opposite of Cold: The Northwoods

Finnish Sauna Tradition. U of Minnesota Press, 2010. 3 Hardy, James D. "The radiating power of human skin in the infrared." Am. J. Physiol 127.454 (1939):

I939. 4 Matos, L. C., et al. "Assessment of Qigong-related effects by infrared thermography= a case study."

Zhong xi yi jie he xue bao= Journal of Chinese integrative medicine 10.6 (2012): 663-666. 5 Whiteside, Dorothy. "Proper use of radiant warmers." AJN The American Journal of Nursing 78.10

(1978): 1694-1696. 6 Why Prestyl Far-Infrared Radiant Heaters?

http://www.innovativegreenenergysolutions.com/page/471103580 7 Dean, Ward. "Effect of Sweating." JAMA 246.6 (1981): 623-623.

8 Law, H. T., and R. T. Pettigrew. "HEAT TRANSFER IN WHOLE‐BODY HYPERTHERMIA." Annals of

the New York Academy of Sciences 335.1 (1980): 298-310. 9 Biro, Sadatoshi, et al. "Clinical implications of thermal therapy in lifestyle-related diseases."

Experimental Biology and Medicine 228.10 (2003): 1245-1249. 10

Pilch, Wanda, et al. "Changes in the lipid profile of blood serumin women taking sauna baths of various duration." International journal of occupational medicine and environmental health 23.2 (2010): 167-174. 11

Gryka, Dorota, et al. "The effect of sauna bathing on lipid profile in young, physically active, male subjects." International journal of occupational medicine and environmental health 27.4 (2014): 608-618. 12

Imamura, Masakazu, et al. "Repeated thermal therapy improves impaired vascular endothelial function in patients with coronary risk factors." Journal of the American College of Cardiology 38.4 (2001): 1083-1088. 13

Beever, Richard. "Do Far-infrared Saunas Have Cardiovascular Benefits in People with Type 2 Diabetes?." Canadian Journal of Diabetes 34.2 (2010): 113-118. 14

Sears, Margaret E., Kathleen J. Kerr, and Riina I. Bray. "Arsenic, cadmium, lead, and mercury in sweat: a systematic review." Journal of environmental and public health 2012 (2012). 15

Eisalo, A., and O. J. Luurila. "The Finnish sauna and cardiovascular diseases." Annals of clinical research 20.4 (1987): 267-270. 16

Kraul, I. and Karlong, P., "Persistent Organochlorinated Compounds in Human Organs Collected in Denmark 1972- 1973," Acta Pharmacol. Toxicol. (Kbh.) 38, 1976, 38-48. 17

Jandacek, Ronald J., and Patrick Tso. "Factors affecting the storage and excretion of toxic lipophilic xenobiotics." Lipids 36.12 (2001): 1289-1305.

Page 13: Allan Rozenberg, PhD - Dynamic Chiropractic · only 10 weeks of far infrared sauna therapy9 Figure 2 Body weight (a) and body fat (b) significantly decreased in 10 obese subjects

© 2015 Wearable Wellness, Inc. Page 13

18

Lambert, G. and Brodeur, J., "Influence of Starvation and Hepatic Microsomal Enzyme Inducation of the Mobilization of DDT Residues in Rats," Tax. App. Pharm. 36. 1976, 111-120. 19

ROOT, DAVID E. "NATIONAL CONFERENCE ON HAZARDOUS WASTES AND ENVIRONMENTAL EMERGENCIES." 20

Ross, Gerald H., and Marie C. Sternquist. "Methamphetamine exposure and chronic illness in police officers significant improvement with sauna-based detoxification therapy." Toxicology and industrial health 28.8 (2012): 758-768. 21

L R Hubbard, The Technical Bulletins (Bridge Publications, Los Angeles, 1980) vol 12, pp 163-181 22

Masuda, Akinori, et al. "The effects of repeated thermal therapy for patients with chronic pain." Psychotherapy and psychosomatics 74.5 (2005): 288-294. 23

Matsumoto, Shuji, et al. "Effects of thermal therapy combining sauna therapy and underwater exercise in patients with fibromyalgia." Complementary therapies in clinical practice 17.3 (2011): 162-166. 24

Masuda A, Kihara T, Fukudome T, Shinsato T, Minagoe S, Tei C. The effects of repeated thermal therapy for two patients with chronic fatigue syndrome. 25

Kihara, Takashi, et al. "Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure." Journal of the American College of Cardiology 39.5 (2002): 754-759. 26

Ikeda, Yoshiyuki, et al. "Repeated thermal therapy upregulates arterial endothelial nitric oxide synthase expression in Syrian golden hamsters." Japanese circulation journal 65.5 (2001): 434-438. 27

Akasaki, Yuichi, et al. "Repeated thermal therapy up-regulates endothelial nitric oxide synthase and augments angiogenesis in a mouse model of hindlimb ischemia." Circulation journal: official journal of the Japanese Circulation Society 70.4 (2006): 463-470. 28

Sobajima, Mitsuo, et al. "Repeated sauna therapy improves myocardial perfusion in patients with chronically occluded coronary artery-related ischemia." International journal of cardiology 167.1 (2013): 237-243.