alkalosis and acidosis project-2
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Respiratory acidosis is a condition of accumulation of carbon
dioxide in the blood
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Produces a shift in the body's pH balance
Causes the body's system to become more acidic
Respiratory acidosis is an acid-base balance disturbance due to
alveolar hypoventilation
Production of carbon dioxide occurs rapidly and failure of
ventilation promptly increases the partial pressure of arterial
carbon dioxide (PaCO2)
The normal reference range for PaCO2 is 35-45 mm Hg
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Respiratory acidosis it is most often caused by pulmonary
problems, although head injuries, drugs (especially anesthetics
and sedatives), and brain tumors can cause this acidemia
Pneumothorax, emphysema, chronic bronchitis, asthma,
severe pneumonia, and aspiration are among the most frequent
causes
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The clinical manifestations are often those of the underlyingdisorder, but can include:
Confusion
Easy fatigue
Lethargy
Shortness of breath
Sleepiness
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Poor organ function
Respiratory failure
Shock
Carbon dioxide narcosis
Muscle dysfunction
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Identifying the underlying cause is priority, a physical examcan be followed by:
Arterial blood gas, which measures oxygen and carbon
dioxide levels in the blood
Basic metabolic panel
Chest x-ray
Pulmonary function test
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Pharmacological Therapies
Bronchodilators
Respiratory stimulants
Drug antagonists
Bicarbonate
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Treatment should be directed at the underlying disorder
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Oxygen therapy
Ventilatory support
Stop smoking
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Do not smoke, smoking leads to the development of many
severe lung diseases that can cause respiratory acidosis
Losing weight may help prevent respiratory acidosis due to
obesity (obesity-hypoventilation syndrome)
Be careful about taking sedating medicines, and never
combine these medicines with alcohol
Take medication as ordered
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Monitor ABGs, to be redrawn every 2 hours
Monitor vital signs and respiratory status (including oxygen
saturation) every 15 minutes for the first hour then every hour
Assess color of skin, nail beds, and oral mucous membranes
every hour
Assess mental status and orientation every hour
Monitor anxiety level as evidenced by restlessness and
agitation
Maintain a calm, quiet environment
Provide reorientation and explain all activities
Keep side rails in place, and place call bell within reach
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Respiratory alkalosis is a condition where the amount ofcarbon dioxide found in the blood drops to a level below
normal range
This condition produces a shift in the body's pH balance and
causes the body's system to become more alkaline
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Respiratory alkalosis results from an elevation in
alveolar ventilation that causes a fall in the partial
pressure of dissolved carbon dioxide
Respiratory alkalosis can be acute or chronic
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Psychiatric causes: anxiety, hysteria and stress
CNS causes: stroke, subarachnoid hemorrhage, meningitis
Drug use: doxapram, aspirin, caffeine and coffee
Moving into high altitude areas, where the low atmospheric
pressure of oxygen stimulates increased ventilation
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Lung disease such as pneumonia, where a hypoxic drivegoverns breathing more than CO2 levels (the normal
determinant)
CO2 level, which stimulates the respiratory center in thebrainstem
Pregnancy
High levels of NH4+ leading to brain swelling and decreased
blood flow to the brain
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Dizziness
Bloating
Light-headedness
Numbness and/or muscle spasms in the extremities
Discomfort in the chest area
Confusion
Dry mouth
Heart palpitations
Feeling short of breath
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Arterial blood gas, which measures oxygen and carbondioxide levels in the blood
Basic metabolic panel
Chest x-ray
Pulmonary function test
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Treatment attempts to eradicate the underlying condition
Treating the condition is a matter of raising carbon dioxide
levels in the blood
Breathe into a paper bag
Get reassurance
Restrict oxygen intake into the lungs
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Sedatives and/or antidepressants should be reserved forpatients who have not responded to conservative
treatment
In mechanically ventilated patients who have
respiratory alkalosis, the tidal volume and/or
respiratory rate may need to be decreased
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Help patient identify factors that precipitate anxiety that leadsto hyperventilation
Help patient find coping mechanisms and activities that
promote relaxation
Breathing exercises, meditation, and regular exercise can also
be effective in prevention
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Watch for and report changes in neurologic, neuromuscular,and cardiovascular functioning
Monitor ABG serum and electrolyte levels closely
Report any variations immediately
Explain all procedures to the patient and allow ample time to
answer any questions
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pH PaCO2 HCO3
7.35 55 257.48 34 23
7.40 40 26
Results
Respiratory
Acidosis
RespiratoryAlkalosis
Normal