agilent openlab: managing instruments, content and processes

Group/Presentation TitleAgilent Restricted

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Agilent OpenLAB: Managing Instruments, Content and Processes

Improving Lab Efficiency and Reducing Instrument Downtime

Pharma/BioPharma Industry Marketing

Christoph Nickel, Software and Informatics Marketing Segment Manager Pharma/BioPharmaSpeaker Title

November, 5, 2007


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Challenges

Laboratories are diverse environments• Analytical raw data from all kind of instruments, often stand-alone• Reports often on paper• Lots of data control in place• Many procedures to follow• Lots of regulations (GxP, 21 CFR Part 11, etc.)• Users need to be able to search and quickly find and retrieve the data,

regardless of their storage location (online or in offline archive)

Must get valuable information out of the diverse data quickly: • Data should be stored on one central system• Data should be comparable and available for review in one common form.

2000 2001 2002 2003 2004 2005 2006

Data GrowthGrowth in Number of Scientists

DataManagementGap


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OpenLAB – one modular system to manage the entire lab:• Scientific Data Management for raw data and reports (centered around PDF)• Chromatographic instrument management for >300 modules• Advanced reporting• Document Management• Workflow automation• Long-term data management and archiving • Easy interfacing with all leading CDS systems

A solution - OpenLAB


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OpenLAB: Modular Approach for Seamless Integration of CDS, ECM and BPM

Chromatography Data System(CDS)

Enterprise Content Manager (ECM) with Workflow Automation (BPM)

Redesigned from the ground up to work as one


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OpenLAB BPM –Workflow

AutomationOpenLAB LIR –

Reporting Database

Modular OpenLAB Configurations 1/3: Combining any CDS with OpenLAB ECM

OpenLAB Enterprise Content Management System

CDS System (any vendor )

Data go into ECM

Standalone CDS with standalone OpenLAB ECM –optional BPM and reporting; data upload for long-term data management in ECM


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Benefits of OpenLAB (ECM/BPM) with 3rd party CDSEnabling paperless lab:

– Long-term management (incl. archving) of all raw data in the lab– Traceable, revision controlled, electronic storage of reports linked to

analytical raw data– Integrated e-sig for all data and easy interoperability with other

applicationsSimplifying and improving compliance:

– All lab-related data in one repository (SOPs, analytical data, reports,…)– Workflow automation for predictable and traceable execution of lab

proceduresImproving Lab efficiency:

– Automation of review and approval for faster batch release– Single report format including grouping, sorting, advanced cross-

sequence calculations, easy data export for all analytical data


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CDS Integration

Modular OpenLAB Configurations 2/3: Tighter Integration of ECM with Agilent CDS

Enterprise Content Management System

Specific tools – Scheduler add-in or desktop integration - for seamless and user friendly bi-directional integration of standalone Agilent CDS with OpenLAB

BPM – workflow Automation

LIR – Database reporting

Agilent CDS Systems:

ChemStation family

ChemStoreEZChrom

Enterprise Content Management System


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Modular OpenLAB Configurations 3/3: Fully integrated OpenLAB ECM and OpenLAB ICM

OpenLAB BPM –Workflow

AutomationOpenLAB LIR –

Reporting Database

OpenLAB Instrument

Control Module (ICM)

OpenLAB Enterprise Content Management System

Full OpenLAB system with Instrument Control, Data Management and optional BPM and reporting from a single application with one UI


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Benefits of fully integrated OpenLAB ApproachEnabling paperless lab:

– Long-term management (incl. archving) of all raw data in the lab– Traceable, revision controlled, electronic storage of reports linked to analytical raw data– Integrated e-sig for all data and easy interoperability with other applications

Simplifying and improving compliance:– All lab-related data in one repository (SOPs, analytical data, reports,…)– Workflow automation for predictable and traceable execution of lab procedures

Improving Lab efficiency:– Automation of review and approval for faster batch release– Single report format including grouping, sorting, advanced cross-sequence calculations, easy data

export for all analytical data– Automated review/approval of results and reports

PLUS Reduced costs for

• System maintenance and validation – one system only• Training and User Education– one application for the entire lab

Higher Lab Uptime through:

• Automation of Instrument Maintenance and access control to OOM instruments


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OpenLAB – functional Overview

Instrument Management

Content Management

Workflow automation

Lab Intelligence reporting

New!


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AICDATA

Control Laboratorynetwork

OpenLAB Instrument Management

Full CDS functionality plus Enterprise Wide Instrument Organization• Locations define the instrument

topography• Limit User access to

instrumentation through the hierarchy

• Instrument portal give high level view into instruments current activities

• Launch instrument control window from the web portal


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OpenLAB – Content Management

Store any recordConvert all reports into PDF files and extract meta data making data searchableView data without native application


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OpenLAB Business Process Management (BPM)

Automate processes in the laboratory without any programming knowledge

Design special “activities” into a template that then runs automatically using MS Visio

Examples:Streamline the data review

process for sample analysis reports including electronic signoff.

Automatically check if a sample analysis report shows impurities in a sample and send an alert.


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Instrument ready to use

OpenLAB Business Process Manger – ExampleInstrument Maintenance

Instrument maintenance process

Alert user

Instrument in maintenance mode

Performmaintenance

Maintenance SOP

Maintenance report


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Overview: Instrument Maintenance Process

• The BPM is triggered and the instrument goes into maintenance mode.

• A user receives the maintenance task in their BPM Inbox, the SOP and a maintenance log are attached.

• The user carries out the maintenance task according to the SOP and fills out the maintenance log.

• The instrument is ready to use again. The maintenance log is accessible from the OpenLAB Instrument Control tab.

The first part of the demo shows the execution of the instrument maintenance process in OpenLAB.


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OpenLAB Intelligence Reporter- a further step to the Paperless LabIncrease efficiency of data review by interactive reporting• Fields to enter or select report parameter

within the final report• Button for displaying details within the

final report. Faster decisions• flag outliers by pass/fail criteria• automatically sort results, etc.)Optimize workflows by integration into OpenLAB ECM• Manage reports with BPM, e.g.

automatic approval process• Secure storage of reports, templates and

queries• Revision control

Instrument_2Instrument_3


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OpenLAB Architecture

OpenLAB OpenLAB Content Content

ManagementManagementServiceService

OpenLABOpenLABDatabaseDatabaseServiceService

OpenLAB OpenLAB Analysis Analysis ServiceService

Network printersNetwork printers

AICAIC Acquisition ControllerAcquisition Controller

OpenLABOpenLAB ClientsClients

OpenLAB ClientsOpenLAB Clients

OpenLAB ClientsOpenLAB Clients

NonNon--OpenLAB OpenLAB instrumentsinstruments

OpenLABOpenLABinstrumentsinstruments

Third party Third party Data systemsData systems


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OpenLAB Laboratory Software Framework

Combination of CDS, ECM and BPM:• Automate laboratory operations and workflows• Manage laboratory desktop content (non-instrument)• Manage and control instrumentation from different vendors• Manage non-controlled instruments and other software

applications• Advanced Reporting• Interface to LIMS and ERP applications

agilent openlab: managing instruments, content and processes

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