advances in biochemical engineering/biotechnology ... · news 5/2013 chemistry 121 t. cremer,...

News 5/2013 Chemistry

119

Advances in Biochemical Engineering/BiotechnologySeries editors: T. Scheper, I. Endo, B. Mattiasson, Editorial board: K. Schügerl, G. N. Stephanopoulos, Ministry of Education, W. S. Hu, J. Nielsen, R. Ulber, P. M. Doran, M. B. Gu, S. Belkin, A.‑P. Zeng, W. Zhou, J.‑J. Zhong

Volume 130

B. Weyand, Medical University Hannover, Germany; M. Dominici, University of Modena, Italy; R. Hass, R. Jacobs, Medizinische Hochschule Hannover, Germany; C. Kasper, Leibniz Universität Hannover, Germany (Eds)

Mesenchymal Stem Cells - Basics and Clinical Application IIContents Engineered MSCs from Patient-Specific iPS Cells, by Irina Eberle, Mohsen Moslem, Reinhard Henschler, Tobias Cantz Fate of Intravenously Injected Mesenchymal Stem Cells and Signifi-cance for Clinical Application, by Beate Wagner, Reinhard Henschler The Implications of Stem Cell Applications for Diseases of the Respiratory System, by Mei Ling Lim, Philipp Jungebluth, Paolo Macchiarini Potential of Mesenchymal Stem Cell Applications in Plastic and Reconstruc-tive Surgery, by Birgit Weyand, Peter M. Vogt General Principles for the Regeneration of Bone and Cartilage, by Michael Jagodzinski, C. Haasper Adult Mesenchymal Stem Cells Explored in the Dental Field, by K. M. Fawzy El-Sayed, C. Dörfer, F. Fändrich, F. Gieseler, M. H. Moustafa, H. Unge-froren Mesenchymal Stem Cell Therapy and Lung Diseases, by Khondoker M. [...]

Fields of interestBiochemical Engineering; Stem Cells; Biomedicine general

Target groupsResearch

Discount groupProfessional Non-Medical

Available

2013. VIII, 295 p. Hardcover7 approx. $259.00ISBN 978-3-642-37943-7

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Advances in Biochemical Engineering/BiotechnologySeries editors: T. Scheper, I. Endo, B. Mattiasson, Editorial board: K. Schügerl, G. N. Stephanopoulos, Ministry of Education, W. S. Hu, J. Nielsen, R. Ulber, P. M. Doran, M. B. Gu, S. Belkin, A.‑P. Zeng, W. Zhou, J.‑J. Zhong

Volume 133

H. Seitz, Fraunhofer-Institut für Biomedizinische Technik IBMT, Potsdam, Germany; S. Schumacher, Fraunhofer Institut für Biomedizinische Technik (IBMT) (Eds)

Molecular DiagnosticsContents Integration in Bioanalysis: Technologies for Point-of-Care Testing, by Frank F. Bier, Soeren Schumacher.- Future of Medicine: Models in Predictive Diagnostics and Personalized Medi-cine, by Babette Regierer, Valeria Zazzu, Ralf Sudbrak, Alexander Kühn and Hans Lehrach.- A Highly Versatile Microscope Imaging Technology Platform for the Multiplex Real-Time Detection of Biomolecules and Autoimmune Antibodies, by Stefan Rödiger, Peter Schierack, Alexander Böhm, Jörg Nitschke, Ingo Berger, Ulrike Frömmel, Carsten Schmidt, Mirko Ruhland, Ingolf Schimke, Dirk Roggenbuck, Werner Lehmann, Christian Schröder.- Platform Technologies for Molecular Diagnostics near the Patient’s Bedside, by Soeren Schumacher, Christine Lüdecke, Eva Ehrentreich-Förster, Frank F. Bier .- Microfluidic Technology for Molecular Diagnostics, by Tom Robinson, Petra S. Dittrich.- Biosensors for Diagnostic Ap-plications, by Friederike J. Gruhl, Bastian E. Rapp, Kerstin Länge. [...]

Fields of interestBiotechnology; Microarrays; Biomedical Engi-neering



Due May 2013

2013. VIII, 170 p. 60 illus., 36 in color. Hardcover7 $259.00ISBN 978-3-642-37690-0

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D. Armstrong, University at Buffalo, NY, USA; D. J. Bharali, Albany College of Pharmacy and Health Sciences, NY, USA (Eds)

Oxidative Stress and NanotechnologyMethods and Protocols

Contents Nanoscale Biosensor for Detection of Reactive Oxygen Species.- Nanoparticles: Toxicity, Radicals, Electron Transfer and Antioxidants.- Encapsula-tion of Anti-Oxidants in Gastrointestinal Resistant Nanoparticulate Carriers.- Toxicity of Novel Nanosized Formulations Used in Medicine.- Fullerenol Nanoparticles: Toxicity and Antioxi-dant Activity.- Hydrogen Peroxide (H2O2) Detec-tion with Nanoprobes for Biological Applications: A Mini-Review.- Studying the Oxidative Stress Paradigm in vitro: A theoretical and Practical Perspective.- Evaluation of the Effect of Acute and Sub-acute Exposure to TiO2 Nanoparticles on Oxidative Stress.- Biomedical Applications of Nano-antioxidant.- Lipid Peroxidation Due to In Vitro and In Vivo Exposure of Biological Samples to Nanoparticles.- Testing Nanomaterial Toxicity in Unicellular Eukaryotic Algae and Fish Cell Lines.- Gold Nanoparticles and Oxidative Stress in the Blue Mussel, Mytilus edulis.- Oxidative Biomarkers to Assess the Nanoparticles Induced Oxidative Stress.- Vesicular Antioxidants: Role in Age-related Cerebral Oxidative Injury.- Methods for Detection of Oxidative Stress and Genotoxic-ity of Engineered Nanoparticles.- Size Dependent Study of Pulmonary Responses to Nano-sized Iron and Copper Oxide Nanoparticles.- In vitro Techniques to Investigate the Oxidative Effects of Quantum Dots.- Hybrid Polymeric Nanoparticles: Potential Candidate for Ophthalmic Delivery.- Relevance of Nanotechnology in Modulating Oxidative Stress: An Overview.

Fields of interestBiotechnology; Nanotechnology

Target groupsProfessional/practitioner


Due June 2013

2013. XVI, 344 p. 53 illus., 23 in color. (Methods in Molecular Biology, Volume 1028) Hardcover7 $139.00ISBN 978-1-62703-474-6

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www.springer.com/978-3-642-37943-7



Chemistry springer.com/NEWSonline

120

A. K. Baev, International Sakharov Environmental University, Minsk, Belarus

Specific Intermolecular Interactions of Nitrogenated and Bioorganic CompoundsAfter his first book on the topic “Specific Intermo-lecular Interactions of Organic Compounds”, Baev extends in this book the development of the thermodynamic theory of specific intermolecular interactions to a wider spectrum of nitrogenated and bioorganic compounds: amino alcohols, amino acids, peptides and urea derivatives. The fundamentals of an unconventional approach to the theory of H-bonding and specific interactions are formulated based on a concept of penta- co-ordinated carbon atoms. New types of hydrogen bonds and specific interactions are substantiated and on the basis of the developed methodology their energies are determined.

Features 7 Describes the development of the thermody-namic theory of specific intermolecular interac-tions 7 Describes a wide spectrum of types of in-termolecular interactions 7 The topic is relevant to organic, bioorganic and synthetic chemistry

Contents From the Contents: Hydrogen Bonds and Specific Intermolecular Interactions of Nitrogenated and Bio-organic Compounds and the Methodology of their Investigation.- Specific Intermolecular Interactions of Cyclic Alkylamines and Nitriles.- Specific Intermolecular Interactions of Cyclic Aromatic Compounds with Nitrogen Atom in their Functional Groups.- Specific Intermolecular Interactions of Nitrogen Containing Five-mem-bered Heterocycles.

Fields of interestTheoretical and Computational Chemistry; Bioor-ganic Chemistry; Physical Chemistry



Due June 2013

2013. XXVIII, 602 p. 407 illus., 9 in color. Hardcover7 $179.00ISBN 978-3-642-37471-5

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C. G. Baker, Kuwait University, Safat, Kuwait (Ed)

Handbook of Food Factory DesignFood manufacturing has evolved over the centu-ries from kitchen industries to modern, sophisti-cated production operations. A typical food fac-tory includes the food processing and packaging lines, the buildings and exterior landscaping, and the utility-supply and waste-treatment facilities.

Features 7 A 'how-to' of food factory design 7 Multi-disciplinary content aimed at wide range of profes-sionals 7 Reference guide for both students and instructors

Contents Introduction.- Part I. Process Considerations.- Process Specifications.- Food Processing Equip-ment.- Hygienic Design of Food-Processing Equipment.- Movement of Materials.- Produc-tivity Issues: Industrial and Operations Man-agement.- Safety and Health.- Protecting the Environment.- Control and Monitoring of Food Manufacturing Processes.- Use of Computers in the Design of Food-Manufacturing Facilities.- Part II. Factory Infrastructure.- Site Considerations.- Design Principles.- Construction: Techniques and Finishes.- Part III. Utilities and Services.- Steam Systems.- Refrigeration Systems.- Heating, Venti-lation and Air Conditioning.- Utilities and Their Conservation.- Effluent Treatment.- Part IV. Proj-ect Engineering Management.- Role of the Project Engineer in the Design Stage.- Role of the Project Engineer in the Construction Stage.

Fields of interestFood Science; Industrial Design; Industrial Chem-istry/Chemical Engineering



Due June 2013

2013. X, 594 p. 124 illus., 12 in color. Hardcover7 $229.00ISBN 978-1-4614-7449-4

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A. K. Chakraborty, Central Glass & Ceramic Research Institute, Jadavpur, India

Phase Transformation of Kaolinite ClayThe book depicts comprehensive studies on thermal decomposition of Kaolinite by different physico-chemical methods carried out by various scientists in last 100 years and results of the stud-ies conducted by author in past 33 years.

Features 7 Provides comprehensive studies on ther-mal decomposition of Kaolinite 7 A critical review on previous studies of Kaolinite–Mullite reaction series 7 Diagnosis of the remaining unsolved problems of Kaolinite–Mullite reaction series 7 Discusses future approaches for further investigational research

Contents Introduction.- Thermal Evolution of Kaolin-ite.- Thermal Methods.- Extraction Tech-niques.- X-Ray Methods.- Electron Microscopy Study.- I.R. Study.- XRF Study.- Radial Electron Density Distribution (RED).- Density & Surface Area Measurement.- Crystallization Studies of Preheated Metakaolinite.- Thermodynamic Ap-proach.- MAS NMR.- QXRD Studies of Phases Formed.- Scanning Electron Microscopic (SEM) Study.- Hot Pressing (RHP) Study.- NAOH Leaching Study.- Various Ways of Characteriza-tion of Alkali Leached Residue.- Meta Kaolinite Phase.- Spinel Phase.- Mullite Phase.- Reasons for First and Second Exothermic Peaks.- Cristobalite Phase.- Topotaxy in K-MK-AL/SI Spinel-Mullite Reaction Series.- Dehydroxylation Mechanism.- Final Conclusion on the Thermal Effects of Kaolinite.- Bibliography.

Fields of interestInorganic Chemistry; Ceramics, Glass, Compos-ites, Natural Materials; Crystallography



Due June 2013

2013. XIII, 463 p. 113 illus. Hardcover7 $129.00ISBN 978-81-322-1153-2

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121

T. Cremer, Harvard University, Cambridge, MA, USA

Ionic Liquid Bulk and Interface PropertiesElectronic Interaction, Molecular Orientation and Growth Characteristics

In this thesis, Till Cremer investigates the bulk properties of ionic liquids (IL), the IL/vacuum interface and the IL/solid interface. For these studies the author primarily uses angle-resolved X-ray photoelectron spectroscopy under ultrahigh vacuum conditions. ILs represent a class of materi-als with unique physico-chemical properties. Many applications take advantage of the extremely low vapor pressure of aprotic ILs to fabricate per-manent, non-volatile liquid coatings on solid ma-terials. The author focuses on issues related to thin IL coatings, in particular concerning new catalytic concepts such as the supported ionic liquid phase (SILP) and solid catalyst with ionic liquid layer (SCILL) systems. Till Cremer presents a number of fundamental contributions to the new field of “Ionic Liquid Surface and Interface Science”.

Features 7 Nominated as an outstanding Ph.D. thesis by the University of Erlangen-Nürnberg 7 First documentation and spectroscopic analysis of ionic liquid thin films deposited on solid materi-als 7 Provides fundamental information on a broad variety of ionic-liquid-based research fields

Contents Introduction and Motivation.- Fundamentals and Techniques.- Pure Ionic Liquid Systems.- Ionic liq-uid — Metal Interfaces.- The Ionic Liquid — Glass Interface and the Nanolab Concept.- Summary and Outlook.

Fields of interestPhysical Chemistry; Theoretical and Computa-tional Chemistry; Surfaces and Interfaces, Thin Films



Due June 2013

2013. 167 p. 72 illus. (Springer Theses) Hardcover7 $129.00ISBN 978-3-319-00379-5

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J. M. Dealy, McGill University, Montreal, QC, Canada; J. Wang, The Dow Chemical Company, Freeport, TX, USA

Melt Rheology and its Applications in the Plastics IndustryContents Preface.- 1.Introduction to Rheology: 1.1 What is rheology?.- 1.2 Why rheological properties are important.- 1.3 Stress- a measure of force.- 1.4 Strain – a measure of deformation.- 1.5 Rheo-logical Phenomena.- 1.6 Why polymeric liquids are non-Newtonian and elastic.- 2.Viscosity and the Normal Stress Differences: 2.1 Simple shear and steady simple shear.- 2.2 Viscometric flow.- 2.3 The viscometric functions.- 2.4 The Viscosity.- 2.5 Normal stress differences.- Refer-ences.- 3. Linear Viscoelasticity: 3.1 Introduc-tion.- 3.2 Stress relaxation and the relaxation modulus.- 3.3 The Boltzmann superposi-tion principle.- 3.4 Start-up of steady simple shear.- 3.5 Relaxation moduli of rubbers and molten polymers.- 3.6 The Maxwell model for the relaxation modulus.- 3.7 The generalized Maxwell model and the discrete relaxation spec-trum.- 3.8 The continuous spectrum.- .9 Creep and creep recovery: The compliance.- 3.10 Start-up of steady simple extension.- 3.11 Small amplitude oscillatory shear.- 3.12 Inferring a discrete relaxation spectrum from storage and loss moduli.- 3.13 Combining creep and oscillatory shear data.- 3.14 Time-temperature superposi-tion.- 3.15 Cole-Cole and related plots of linear data.- 3.16 Van Gurp-Palmen Plot of Loss Angle Versus Complex Modulus.- 3.17 Storage and loss moduli of molten linear polymers. [...]

Fields of interestPolymer Sciences; Industrial Chemistry/Chemical Engineering; Characterization and Evaluation of Materials



Due April 2013

2nd ed. 2013. XVI, 276 p. 145 illus., 3 in color. (Engineering Materials and Processes) Hardcover7 $179.00ISBN 978-94-007-6394-4

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M. Fedotov, Boreskov Catalysis Institute, Novosibirsk, Russia

NMR in Inorganic and Coordination ChemistryThe present text provides detailed information for the application of NMR in inorganic and coor-dination chemistry. Detailed, yet clear derivations of all relevant equations are provided throughout. These offer not only a very good introductory basis for those new to NMR, but also many practi-cal work-ups for those already familiar with this technique but who wish to apply it to specific in-organic compounds. The reader is given in-depth background on NMR methods, its restrictions and advantages over other characterization methods. A convenient listing for isotopes of each ele-ment is provided as a handy reference. NMR data for compounds of all elements with numerous examples of NMR applications in analytic and physical chemistry are presented.

Features 7 Covers theory and background of nuclear magnetic resonance in an accessible yet thorough manner 7 Specific methods and work-ups for isotopes are provided 7 Demonstrates uses of NMR for investigation in inorganic and coordina-tion chemistry 7 Covers latest developments in inorganic NMR techniques

Contents Nuclear magnetic resonance – methodology and experiments.- Nuclear magnetic resonance of non-transitional elements.-Nuclear Magnetic Resonance of Transition Elements.- Some applica-tions of NMR.

Fields of interestInorganic Chemistry; Characterization and Evalu-ation of Materials; Spectroscopy and Microscopy



Due July 2013

2013. Approx. 380 p. 100 illus. Hardcover7 approx. $179.00ISBN 978-1-907343-83-4

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122

A. Gueven, Tunceli University, Turkey; Z. H. Katnas, Trakya University, Edirne, Turkey

Pore Structure in FoodSimulation, Measurement and Application

The pore structure of foods directly affects the success of such food processes as drying, puffing, freeze-drying, and rehydration. Consequently, the pore structure of foods determines what types of food processes will work best with a particular food. This Brief will first discuss in depth the need to correctly measure the pore structure of foods and then will identify and describe in detail the current methods available to measure food poros-ity. Finally, it will review the applications of these various methods.

Contents Introduction.- Quantitative Measurement of the Pore Structure.- Pore Structure and Texture.- Sim-ulation of the Pore Structure of Food Materials.- Applications of the Pore Network Model to Food Systems.- Conclusions.- References.

Fields of interestFood Science; Biotechnology; Mathematical Mod-eling and Industrial Mathematics



Due June 2013

2013. V, 50 p. 8 illus. (SpringerBriefs in Food, Health, and Nutrition) Softcover7 $49.99ISBN 978-1-4614-7353-4

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K. Hamad‑Schifferli, Massachusetts Institute of Technology, Cambridge, MA, USA; P. Bergese, Università degli Studi di Brescia, Italy (Eds)

Nanomaterial Interfaces in BiologyMethods and Protocols

Contents Preparation of 2 nm Gold Nanoparticles for In vitro and In vivo Applications.- DNA Conjugation to Nanoparticles.- Conjugation of Nanoparticles to Proteins.- Water-Solubilization and Functional-ization of Semiconductor Quantum Dots.- Synthe-sizing and Modifying Peptides for Chemoselective Ligation and Assembly into Quantum Dot-Peptide Bioconjugates.- Reliable Methods for Silica Coat-ing of Au Nanoparticles.- Surface Modifications by Polymers for Biomolecule Conjugation.- Func-tionalization Protocols of Silicon Micro-Nano-Mechanical Biosensors.- Stability and Aggregation Assays of Nanoparticles in Biological Media.- Electrochemical Measurements of DNA Melting on Surfaces.- Formation and Characterization of Nanoparticle-Protein Corona.- Electrophoretic Implementation of the Solution-Depletion Meth-od for Measuring Protein Absorption, Adsorption Kinetics, and Adsorption Competition Among Multiple Proteins in Solution.- Hyperspectral Mi-croscopy for Characterization of Gold Nanopar-ticles in Biological Media and Cells for Toxicity Assessment.- Immunochemistry, Electron Tomog-raphy and Energy Dispersive X-Ray Spectroscopy (EDXS) on Cryosections of Human Cancer Cells Doped with Stimuli Responsive Polymeric Nanogels Loaded with Iron Oxide Nanoparticles.- Zwitterion Siloxane to Passivate Silica Against Non-Specific Protein Adsorption.- Preparation and Characterization of DNA Block Copolymer Assemblies Loaded with Nanoparticles. [...]




Due June 2013

2013. XIV, 302 p. 69 illus., 51 in color. (Methods in Molecular Biology, Volume 1025) Hardcover7 $119.00ISBN 978-1-62703-461-6

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R. W. Hartel, University of Wisconsin, Madison, WI, USA; A. Hartel, Northland College, Ashland, WI, USA

Food BitesThe Science of the Foods We Eat

Contents What is Food Science.- Processed Foods: Good or Bad?.- Vintage Wines and Chocolates.- Preserving Strawberries, and Other Foods.- Science Projects in Your Refrigerator.- Freeze Drying – High-Qual-ity Food.- Does Your Food Glow in the Dark.- Is Your Food Safe?.- Food Safety and Mobile Food Carts.- At Work in a Vale of Tears.- Are All Microorganisms in Food Bad?.- Probiotics – The Growth of Cultured Foods.- How to Keep Gua-camole from Turning Brown.- Churning the But-ter.- What Side Is Your Bread Buttered on?.- But-ter or Margarine?.- Chocolate Flavor.- Rice in Your Salt Shaker.- Frost on Your Berries.- Lucky Charms – A Lesson in Creativity and Market-ing.- Developing New Ice cream Flavors.- Oreos Spawn Host of New Products.- Sparkler Spice! for Your Veggies?.- It Is All in the Packaging.- Shelf Life Dating – Good or Bad?.- Intelligent Pack-ages.- Juice Boxes for Your Convenience.- Beware of Low-Carb Diets.- May Contain Peanuts! - What is a Food Allergy?.- Uses of Chocolate Pud-ding.- The Magic of Gelatin.- Pretzels.- Peanut Butter.- Cheddarwurst.- Ice - From Nature to Frozen Desserts.- It is Popsicle Time.- Neapolitan Ice Cream.- Sprinkles or Jimmies?.- California or Wisconsin Raisins?.- Eat Your Tomatoes Raw or Cooked - Just Eat Them.- Fruit Leather.- Pre-serving Apples for Next Spring.- Fruitcake: A Scorned Food.- Mom Versus Betty Crocker: Is Cake Made from Scratch Better Than Cake Made from a Box?.- Holiday Cookies - Butter, Margarine or Shortening?.- Animal Crackers or Cookies?.- Skunky Beer for Oktoberfest?.- This Oktoberfest, Drink the Beer, Not the Water. [...]

Fields of interestFood Science; Chemistry/Food Science, general; Popular Science, general

Target groupsPopular/general


Due April 2013

2013. X, 180 p. Softcover7 approx. $19.99ISBN 978-1-4614-7563-7

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123

K. Hiraoka, University of Yamanashi, Kofu, Japan (Ed)

Fundamentals of Mass SpectrometryMost research and all publications in mass spec-trometry address either applications or practical questions of procedure. This book, in contrast, discusses the fundamentals of mass spectrometry. Since these basics (physics, chemistry, kinetics, and thermodynamics) were worked out in the 20th century, they are rarely addressed nowadays and young scientists have no opportunity to learn them. This book reviews a number of useful methods in mass spectrometry and explains not only the details of the methods but the theoretical underpinning.

Features 7 Explains basics of mass spectrometry 7 Dis-cusses fundamentals of the methods, not applications or details of use of mass spectrom-etry 7 Enables readers to understand results derived from mass spectrometry

Contents Basic Explanation for Collisions in Mass Spec-trometry.- Super-excited States of Molecules.- Fundamental Aspects of Photoionization of Molecules.- Chemical Reaction by Core Electron Excitation.- Ion Mobility Spectrometry.- Gas Phase Ion Molecule Reactions.- Fundamentals of Electrospray.- Secondary Ion Mass Spectrometry.- Isotope Ratio Mass Spectrometry.- Theory of Ion Fragmentation.

Fields of interestAnalytical Chemistry; Mass Spectrometry; Spec-troscopy/Spectrometry



Due May 2013

2013. X, 360 p. 134 illus., 56 in color. Hardcover7 $229.00ISBN 978-1-4614-7232-2

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T. Hyötyläinen, Maj and Thor Nessling Foundation, Helsinki, Finland (Ed)

Comprehensive Two-Dimensional ChromatographyThe first book on comprehensive chromatography to cover two-dimensional techniques for both liquid and gas chromatography. These techniques allow highly efficient analysis of very complex analytes, such as environmental, agricultural or biological samples. The authors cover essential theoretical aspects, the instrumentation as well as the practical application of these techniques. The latter is presented in numerous examples from environmental and food analysis, including flavor and fragrances, petrochemical and other industrial applications as well as metabolomical and bio-medical applications.

Feature 7 The first book on comprehensive chromatogra-phy to cover both liquid and gas chromatography

Contents Theory of multidimensional separations.- Data analysis in comprehensive two-dimensional separations.- Comprehensive two-dimensional gas chromatography.- Comprehensive two-dimen-sional liquid chromatography.- Comprehensive two-dimensional liquid chromatography- gas chromatography.- Applications.

Fields of interestChromatography; Molecular Medicine; Monitor-ing/Environmental Analysis



Due May 2013


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G. Inzelt, Eötvös Loránd University, Budapest, Hungary; A. Lewenstam, Center for Process Analytical Chemistry and Sensor Technology “ProSens”, Process Chemistry Center, Åbo Akademi University, Abo, Finland; F. Scholz, University of Greifswald, Germany (Eds)

Handbook of Reference ElectrodesReference Electrodes are a crucial part of any electrochemical system, yet an up-to-date and comprehensive handbook is long overdue.

Features 7 The only handbook on this topic 7 Provides reliable data for the proper choice and con-struction of reference electrodes for all kinds of electrochemical systems 7 Clear and illustrated presentation of the required basic know-how

Contents Electrode potentials.- Reference redox systems in non-aqueous systems and the relation of electrode potentials in non-aqueous and mixed solvents to standard potentials in water.- Liquid junction potentials.- Salt bridges and diaphragms.- Refer-ence electrodes for aqueous solutions.- Reference Electrodes for Use in Nonaqueous Solutions.- Reference electrodes for ionic liquids and molten salts.- Reference Electrodes in Oxidic Glass Melts.- Reference electrodes for solid electro-lyte devices.- Direct solid contact in reference electrodes.- Micro reference electrodes.- Conduct-ing polymer based reference electrodes.- Screen-printed, disposable, reference electrodes.- Pseudo-reference electrodes.- The Kelvin Probe technique as reference electrode for application on thin and ultra-thin electrolyte films.

Fields of interestElectrochemistry; Analytical Chemistry



Due April 2013

2013. XII, 344 p. 88 illus., 30 in color. Hardcover7 $179.00ISBN 978-3-642-36187-6

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124

S. Kalia, Bahra University, Himachal Pradesh, India; S.‑Y. Fu, Technical Institute of Physics and Chemistry, Beijing, China (Eds)

Polymers at Cryogenic TemperaturesKalia and Fu’s novel monograph covers cryogenic treatment, properties and applications of cryo-treated polymer materials. Written by numerous international experts, the twelve chapters in this book offer the reader a comprehensive picture of the latest findings and developments, as well as an outlook on the field. Cryogenic technology has seen remarkable progress in the past few years and especially cryogenic properties of polymers are attracting attention through new breakthroughs in space, superconducting, magnetic and electronic techniques.

Features 7 This book deals with the very hot topic of very cold (cryogenic) temperatures 7 Used for new developments in space, superconducting magnets and electronic techniques 7 Written by interna-tional experts in the field

Contents From the Contents: Cryogenic Processing: State of the art, Advantages and Applications.- Cryogenic properties of polymer materials.- Friction & wear of polymer materials at cryogenic temperatures.- Mechanical behaviour of polymer composites at cryogenic temperatures.- Interlaminar Delamina-tion Fracture and Fatigue of Woven Glass Fiber Reinforced Polymer Composite Laminates at Cryogenic Temperatures.- The behaviour of polymer based dielectrics under cryogenic condi-tions.- Medical applications of poly(vinyl alcohol) cryogels.

Fields of interestPolymer Sciences; Soft and Granular Matter, Complex Fluids and Microfluidics; Optical and Electronic Materials



Available


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S. Kobayashi, Kyoto Institute of Technology, Japan; K. Müllen, Max-Planck-Institut für Polymerforschung, Mainz, Germany (Eds)

Encyclopedia of Polymeric NanomaterialsOver the last few years, nanoscience and nano-technology have been the focus of significant research attention, both from academia and in-dustry. This sustained focus has in-turn driven the interdisciplinary field of material science research to the forefront of scientific inquiry through the creation and study of nanomaterials.

Features 7 First concise book on polymeric nanomateri-als 7 Provides an overview to the concepts, practices and applications in the field

Fields of interestPolymer Sciences; Nanotechnology; Condensed Matter Physics



Due March 2014

Print

2 Volumes, not published separately

2014. 2000 p. 7 approx. $679.00ISBN 978-3-642-29647-5

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2014. 7 approx. $679.00ISBN 978-3-642-29648-2

9<HTOGPC=cjgeic> Print + eReference


2014. 2000 p. 7 approx. $849.00ISBN 978-3-642-29649-9

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K.‑H. Koch, J. Flock

Process Analytical ChemistryControl, Optimization, Quality, Economy

In important branches of manufacturing in-dustries, especially those producing chemicals, polymers, semiconductors, ceramics, metals and alloys, analytical process control is already an integral part of the company. Far reaching deci-sions with respect to quality, ecology and economy are based on the respective analytical data. The goal of this practice-oriented book is to introduce chemists, engineers and technicians to the strate-gies, techniques and efficiency of modern process analytical chemistry. The authors are especially aiming at those professionals in small and me-dium enterprises who have to carry out process control tasks in a “solo-run”.

Features 7 Comprehensive overview for chemists and en-gineers 7 Focus is on optimization, automation and quality control in industry including small and medium-sized companies

Contents Process Analytics of Gases.- Process Analyt-ics of Liquid Phases.- Process Analytics of Solid Materials.- Process Analytics in the Chemical Industry.- Metallurgical Process Technology and Chemical Process Analysis.- Process Analytics in the Semiconductor Industry.- Process Technology and Environment.- The Chemical Process Analyt-ics as Part of Quality Management and Quality Assurance.- Economy of Industrial Analytics.- Outlook on Research and Development Trends in Industrial Process and Product Analytics.

Fields of interestAnalytical Chemistry; Industrial Chemistry/Chemical Engineering; Ecotoxicology



Due April 2013

2nd ed. 2013. Approx. 340 p. 110 illus. Hardcover7 approx. $179.00ISBN 978-3-642-10717-7

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125

G. Korotcenkov, Gwangju Institute of Science and Technology, Korea

Handbook of Gas Sensor MaterialsProperties, Advantages and Shortcomings for Applications Volume 1: Conventional Approaches

The two volumes of Handbook of Gas Sensor Materials provide a detailed and comprehensive account of materials for gas sensors, including the properties and relative advantages of various materials. Since these sensors can be applied for the automation of myriad industrial processes, as well as for everyday monitoring of such activi-ties as public safety, engine performance, medical therapeutics, and in many other situations, this handbook is of great value. Gas sensor designers will find a treasure trove of material in these two books.

Features 7 First book to comprehensively cover materi-als for gas sensors 7 In-depth discussion of gas sensor materials 7 Ease of comparative analysis of gas sensor materials 7 Many tables make the book very useful for gas sensor design

Contents Conventional gas sensing materials.- Auxiliary materials.- Materials for specific gas sensors.- Nanostructured gas sensing materials.- Other trends in design of gas sensor materials.- Nano-composites.- Stability of gas sensing materials and related processes.- Structure and surface modifica-tions of gas sensing materials.- Technology and sensing material selection.

Fields of interestAnalytical Chemistry; Characterization and Evaluation of Materials; Electrochemistry



Due June 2013

2013. XX, 440 p. 216 illus., 1 in color. Hardcover7 $229.00ISBN 978-1-4614-7164-6

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G. Korotcenkov, Gwangju Institute of Science and Technology, Korea

Handbook of Gas Sensor MaterialsProperties, Advantages and Shortcomings for Applications Volume 2: New Trends and Technologies

The two volumes of Handbook of Gas Sensor Materials provide a detailed and comprehensive account of materials for gas sensors, including the properties and relative advantages of various materials. Since these sensors can be applied for the automation of myriad industrial processes, as well as for everyday monitoring of such activi-ties as public safety, engine performance, medical therapeutics, and in many other situations, this handbook is of great value. Gas sensor designers will find a treasure trove of material in these two books.

Features 7 Real encyclopedia-handbook 7 Contains various tables with information necessary for gas sensor design 7 Provides understanding of fundamentals of sensor functioning 7 Provides information about applications in various types of gas sensors

Contents Conventional gas sensor materials.- Auxiliry ma-terials.- Materials for specific gas sensors.- Nano-structered gas sensing materials.- Other trends in design of gas sensor materials.- Nanocompos-ites.- Stability of gas sensing materials and related processes.- Structure and surface modifications of gas sensing materials.

Field of interestChemistry/Food Science, general



Due June 2013

2013. XI, 441 p. 246 illus. Hardcover7 $179.00ISBN 978-1-4614-7387-9

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A. V. Naimpally, California State University, Long Beach, CA, USA; K. Rosselot, Process Profiles, Calabasas, CA, USA

Environmental Engineering Review for the Professional Engineering ExaminationThis book will help the reader expand further into chemical engineering and become a licensed professional engineer (PE), which can offer a tre-mendous boost to one’s career, as there are certain career opportunities available only to licensed en-gineers. Licensure demonstrates high standards of professionalism, knowledge, and ability. Because of the work experience requirement, PE examinees have generally been out of school for some time. This book summarizes the theoretical background of topics covered in the exam, which will help potential examinees refresh their memories on subjects they may not have been exposed to since their undergraduate classes.

Features 7 Book summarizes theoretical background of topics covered in exam 7 Includes two or three "logical distractors" (answers that result from com-mon mistakes) among the answer choices for each problem

Contents Water and wastewater.- Groundwater, soils, and remediation.- Air.- Solid waste.- Hazardous waste.- Environmental assessments and emergen-cy response.- Error and uncertainty in environ-mental measurements.

Fields of interestIndustrial Chemistry/Chemical Engineering; Engineering, general



Due July 2013


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126

A. Patel, Maharaja Sayajirao University of Baroda, Gujarat, India (Ed)

Environmentally Benign CatalystsFor Clean Organic Reactions

Contents Introduction.- Heteropoly compounds as am-moxidation catalysts.- Transition metal substituted salt of tungsten based polyoxometalates sup-ported mesoporous silica as a Catalyst for Organic Transformation reactions.- Vanadium substituted tugstophosphoric acid supported on titania: A het-erogeneous catalyst for selective oxidative cleavage of olefins to carbonyl compounds at room tem-perature.- Supported Heteropoly Acids and Mul-ticomponent Polyoxometalates as Eco-Friendly Solid Catalysts for Bulk and Fine Chemicals Syn-thesis.- Glycerol Etherification with light Alcohols Promoted by Supported H3PW12O40.- Alkoxyl-ation of Terpenes over Tungstophosphoric Acid Immobilised on Silica Support.- Effect of acidity, structure and stability of supported 12-tungsto-phosphoric acid on catalytic reactions.- Biodiesel production over 12-tungstosilisic acid anchored to different mesoporous silica supports.- Solvent free selective oxidation of benzyl alcohol to benzal-dehyde over mono lacunary phosphomolybdate supported onto hydrous zirconia.- H3PMo12O40 Heteropolyacid: A Versatile and Efficient Bifunc-tional Catalyst for the Oxidation and Esterifica-tion Reactions.- Electrochemical/ElectroCatalytic Applications of Polyoxometalates.

Fields of interestCatalysis; Industrial Chemistry/Chemical Engi-neering; Organic Chemistry



Due June 2013

Jointly published with Panch Tattva Publishers, Pune, India

2013. 200 p. 159 illus., 57 in color. Hardcover7 $129.00ISBN 978-94-007-6709-6

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S. J. Rosenthal, D. W. Wright, Vanderbilt University, Nashville, TN, USA (Eds)

NanoBiotechnology ProtocolsContents High Aspect Ratio Gold Nanorods: Their Synthe-sis and Application to Image Cell-Induced Strain Fields in Collagen Films.- Imaging Intracellular Quantum Dots: Fluorescence Microscopy and Transmission Electron Microscopy.- Imaging of Cell Populations in Atherosclerosis Using Quan-tum Dot Nanocrystals.- Imaging of Endothelial Progenitor Cell Subpopulations in Angiogenesis using Quantum Dot Nanocrystals.- Imaging Single Synaptic Vesicles in Mammalian Cen-tral Synapses with Quantum Dots.- Quantum Dot-Based Single-Molecule Microscopy for the Study of Protein Dynamics.- Three-dimensional Molecular Imaging with Photothermal Optical Coherence Tomography.- Detecting Respiratory Syncytial Virus Using Nanoparticle Amplified Im-muno-PCR.- Gold Nanoparticle-Oligonucleotide Conjugates for the Profiling of Malignant Mela-noma Phenotypes.- Methods for Isolating RNA Sequences Capable of Binding to or Mediating the Formation of Inorganic Materials.- Single-Walled Carbon Nanotube-Mediated Small Interfering RNA Delivery and Silencing Gastrin-Releasing Peptide Receptor in Human Neuroblastoma Cells.- Amino Acid Mediated Linear Assembly of Au Nanomaterials.- Enzyme—Gold Nanoparticle Bioconjugates: Quantification of Particle Stoichi-ometry and Enzyme Specific Activity.- In Vivo Testing for Gold Nanoparticle Toxicity.- Methods for Studying of Toxicity of Silica-based Nanomate-rials to Living Cells.




Due June 2013

2nd ed. 2013. XII, 212 p. 59 illus., 39 in color. (Methods in Molecular Biology, Volume 1026) Hardcover7 $119.00ISBN 978-1-62703-467-8

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M. Schädel, GSI Helmholtz Centre for Heavy Ion Research GmbH, Darmstadt, Germany; D. Shaughnessy, Lawrence Livermore National Laboratory, CA, USA (Eds)

The Chemistry of Superheavy ElementsThe second edition of “The Chemistry of the Su-perheavy Elements” provides a complete coverage of the chemistry of a series of elements beginning with atomic number 104 – the transactinides or superheavy elements – including their nuclear properties and production in nuclear reactions at heavy-ion accelerators.

Features 7 Provides complete coverage of the super-heavy elements beginning with atomic number 104 7 The contributing authors have made vast contributions to understanding the physics and chemistry of the superheavy elements in the past decades 7 A complete up-to-date source for ad-vanced teachers and students of nuclear chemistry

Contents Synthesis of Super heavy Elements.- Nuclear Structure of Super heavy Elements.- Theoretical Chemistry of the Heaviest Elements.- Fundamen-tal and Experimental Aspects of Single Atom-at-a-Time Chemistry.- Experimental Tech-niques.- Liquid-Phase Chemistry of Super heavy Elements.- Thermochemical Data from Gas-Phase Adsorption and Methods of their Estimation.- Gas-Phase Chemistry of Super heavy Elements.- Historical Reminiscences: The Pioneering Years of Super heavy Element Research.

Fields of interestNuclear Chemistry; Nuclear Physics, Heavy Ions, Hadrons; Physical Chemistry



Due May 2013

2nd ed. 2013. VI, 554 p. 217 illus., 48 in color. Hardcover7 $229.00ISBN 978-3-642-37465-4

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127

T. Scheby Kuhlman, Technical University of Denmark, Lyngby, Denmark

The Non-Ergodic Nature of Internal ConversionAn Experimental and Theoretical Approach

This thesis investigates the transitions from one electronically excited state to another. Such processes - the fastest of events in chemistry - can be studied with femtosecond resolution, and Thomas S. Kuhlman approaches the question both with experimental and theoretical methods. His approach contributes to explain processes of high importance to all scientific fields concerned with the interaction between light and matter: the de-activation of the electronically excited states after excitation. Thomas S. Kuhlman concludes in this thesis that the electronic transition proceeds be-fore the entire set of available degrees of freedom are active - ‘It is as simple as that’ !

Features 7 Nominated by the Technical University of Den-mark as an outstanding PhD thesis 7 Sheds light on the fastest of events in chemistry: transitions between electronically excited states 7 Clarifies the mechanims of deactivation of excited states after the interaction of light and matter

Contents Part I Introduction.- Part II Experimental Meth-ods: Experimental Setup.- Fitting of Experimental Data and Cross-Correlation.- Part III Theoretical Methods: Nuclear Dynamics.- Time-Resolved Photoelectron Spectra.- Electronic Structure.- Part IV Results and Discussion: The Cycloketones.- The Cyclopentadienes.- Dithiane.- Part V Concluding Remarks: Summarizing Discussion.

Fields of interestPhysical Chemistry; Atomic/Molecular Structure and Spectra; Theoretical and Computational Chemistry



Due May 2013

2013. XVI, 161 p. 48 illus., 44 in color. (Springer Theses) Hardcover7 $129.00ISBN 978-3-319-00385-6

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W. Tang, Nanjing University of Science and Technology, China; S.‑C. Ng, Nanyang Technological University, Singapore; D. Sun, Nanjing University of Science and Technology, China (Eds)

Modified Cyclodextrins for Chiral SeparationModified Cyclodextrins for Chiral Separation offers a review of the latest advances in develop-ing modified cyclodextrins as chiral selectors for various chromatographic and electromigration techniques.

Features 7 Reviews the whole spectrum of neutral and charged cyclodextrins for capillary electropho-resis 7 Introduces a new family of cyclodex-trin-based chiral stationary phases for various chromatographic techniques 7 Helps analytical researchers to understand the structural design principle of cyclodextrins for specific chiral sepa-ration techniques 7 Provides multi-disciplinary insights into synthetic organic chemistry, analyti-cal chemistry, and pharmaceutical science with an integrated perspective into both research and practical applications

Contents Modification of Cyclodextrin.- Cyclodextrin-based Chiral Stationary Phases for Gas Chroma-tography.- Cyclodextrin-based Chiral Stationary Phases for High-Performance Liquid Chroma-tography.- Cyclodextrin-based Chiral Stationary Phases for Supercritical Fluid Chromatogra-phy.- Native β-cyclodextrins and Their Neutral Derivatives for Capillary Electrophoresis.- Anionic Cyclodextrins for Capillary Electrophoresis.- Cat-ionic Cyclodextrins for Capillary Electrophoresis.

Fields of interestChromatography; Electrophoresis; Organic Chemistry



Due May 2013

2013. XII, 394 p. 88 illus., 20 in color. Hardcover7 $129.00ISBN 978-3-642-37647-4

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Z. V. Todres, Belmont, MA, USA

Organic Chemistry in Confining MediaZory Vlad Todres’ monograph offers a fresh insight into an important and developed area of organic chemistry. Calixarene, cyclodextrins, and cucurbiturils as host molecules are well known, but the corresponding new and demonstrative publications deserve new exposition. This book principally widens our consideration of organic reactivity in confining media. Topics discussed include: effects of micellization, porous effects, effects of solvent cages, complexation to organo-metallic compounds, hydrogen-bond or charge-transfer complexation, sorption effects, effects of solvents, and stereochemical changes upon con-finement. Organic Chemistry in Confining Media is useful for experienced organic chemists working in academia or industry, as well as chemists work-ing in fields contiguous to organic chemistry.

Features 7 Includes lesser discussed topics such as transformations within micelles, porous materials, solvent cages, hydrogen-bond or charge-transfer complexes 7 Addresses practical applications of the confinement effects 7 Widens the discussion on confinement effects in chemistry

Contents Encapsulation effects.- Resin-docking, surface-bound and polymer-penetration effects.- Reac-tions within charge-transfer complexes.- Effects of hydrogen bonding.- Effects of coordination to metals.- Effects of sorption.- Micellar effects.- Cage effects of solvents, proteins and crystal lattices.- Pore effects.- Stereochemical outcomes of confinement.- The role of solvents in confined or-ganic and organometallic reactions.- Conclusions.

Field of interestOrganic Chemistry



Due June 2013

2013. XIII, 426 p. 223 illus., 201 in color. Hardcover7 $179.00ISBN 978-3-319-00157-9

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128

Topics in Current ChemistrySeries editors: K. N. Houk, J.‑M. Lehn, S. V. Ley, J. Thiem, C. A. Hunter, M. Venturi, C.‑H. Wong, H. N. Wong, M. J. Krische, M. Olivucci

Volume 328

S. Jackson, University of Cambridge, UK (Ed)

Molecular ChaperonesAssisting Oxidative Protein Folding: How Do Protein Disulphide-Isomerases Couple Confor-mational and Chemical Processes in Protein Fold-ing?, by A. Katrine Wallis and Robert B. Freedman Peptide Bond cis/trans Isomerases: A Biocatalysis Perspective of Conformational Dynamics in Proteins, by Cordelia Schiene-Fischer, Tobias Aumüller and Gunter Fischer Small Heat-Shock Proteins: Paramedics of the Cell, by Gillian R. Hil-ton, Hadi Lioe, Florian Stengel, Andrew J. Baldwin und Justin L. P. Benesch Allostery in the Hsp70 Chaperone Proteins, by Erik R. P. Zuiderweg, Eric B. Bertelsen, Aikaterini Rousaki, Matthias P. Mayer, Jason E. Gestwicki and Atta Ahmad Hsp90: Structure and Function, by Sophie E. Jackson Extracellular Chaperones, by Rebecca A. Dabbs, Amy R. Wyatt, Justin J. Yerbury, Heath Ecroyd and Mark R. Wilson

Features 7 This series presents critical reviews of the present position and future trends in modern chemical research 7 Short and concise reports on chemistry, each written by the world renowned experts 7 Still valid and useful after 5 or 10 years 7 More information as well as the elec-tronic version of the whole content available at: springerlink.com

Fields of interestBioorganic Chemistry; Protein Science; Biophysics and Biological Physics



Available

2013. VII, 272 p. 55 illus., 45 in color. Hardcover7 $309.00ISBN 978-3-642-34551-7

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Volume 333

P. Cintas, University of Extremadura, Badajoz, Spain (Ed)

BiochiralityOrigins, Evolution and Molecular Recognition


Contents Early History of the Recognition of Molecular Biochirality, by J. Gal P. Cintas .- Synthesis and Chirality of Amino Acids Under Interstellar Conditions, by C. Giri, F. Goesmann, C. Meinert A. C. Evans U. J. Meierhenrich .- Chemical and Physical Models for the Emergence of Biological Homochirality, by J. E. Hein, D. Gherase, Donna G. Blackmond .- Biomolecules at Interfaces: Chiral, Naturally, by A. González-Campo, D. B. Amabilino .- Stochastic Mirror Symmetry Break-ing: Theoretical Models and Simulation of Experi-ments, by C. Blanco, D. Hochberg.- Self-Assembly of Dendritic Dipeptides as a Model of Chiral Selection in Primitive Biological Systems, by B. M. Rosen, C. Roche, V. Percec.- Chirality and Protein Biosynthesis, by S. Dutta Banik, N. Nandi.

Fields of interestOrganic Chemistry; Evolutionary Biology; Astro-biology



Due May 2013


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Volume 334

G. Erker, University of Münster, Germany; D. W. Stephan, University of Toronto, ON, Canada (Eds)

Frustrated Lewis Pairs IIExpanding the Scope

Contents Frustrated Lewis Pairs: From Dihydrogen Activa-tion to Asymmetric Catalysis, by Dianjun Chen, Jürgen Klankermayer.- Coexistence of Lewis Acid and Base Functions: A Generalized View of the Frustrated Lewis Pair Concept with Novel Impli-cations for Reactivity, by Heinz Berke, Yanfeng Jiang, Xianghua Yang, Chunfang Jiang, Subrata Chakraborty, Anne Landwehr.- New Organobo-ranes in “Frustrated Lewis Pair” Chemistry, by Zhenpin Lu, Hongyan Ye, Huadong Wang.- Para-cyclophane Derivatives in Frustrated Lewis Pair Chemistry, by Lutz Greb, Jan Paradies .- Novel Al-Based FLP Systems, by Werner Uhl, Ernst-Ulrich Würthwein.- N-Heterocyclic Carbenes in FLP Chemistry, by Eugene L. Kolychev, Eileen Theuergarten, Matthias Tamm.- Carbon-Based Frustrated Lewis Pairs, by Shabana Khan, Manuel Alcarazo.- Selective C-H Activations Using Frus-trated Lewis Pairs. Applications in Organic Syn-thesis, by Paul Knochel, Konstantin Karaghiosoff, Sophia Manolikakes.- FLP-Mediated Activations and Reductions of CO2 and CO, by Andrew E. Ashley, Dermot O’Hare.- Radical Frustrated Lewis Pairs, by Timothy H. Warren and Gerhard Erker. [...]

Fields of interestOrganic Chemistry; Catalysis; Theoretical and Computational Chemistry



Due May 2013

2013. VIII, 307 p. Hardcover7 $349.00ISBN 978-3-642-37758-7

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129


Volume 335

H. Heise, Heinrich Heine University Düsseldorf, Germany; S. Matthews, Imperial College London, UK (Eds)

Modern NMR MethodologyNMR Spectroscopy for Chemical Analysis at Low Magnetic Fields, by Stefan Glöggler, Bernhard Blümich, Stephan Appelt Dynamic Nuclear Hy-perpolarization in Liquids, by Ulrich L.


Contents NMR Spectroscopy for Chemical Analysis at Low Magnetic Fields, by Stefan Glöggler, Bernhard Blümich, Stephan Appelt.- Dynamic Nuclear Hyperpolarization in Liquids, by Ulrich L. Gün-ther.- NMR with Multiple Receivers, by Eriks Kupce.- TROSY NMR Spectroscopy of Large Soluble Proteins, by Yingqi Xu, Stephen Mat-thews.- Solid-State NMR Spectroscopy of Proteins, by Henrike Müller, Manuel Etzkorn, Henrike Heise .- Paramagnetic Solid-State Magic-Angle Spinning NMR Spectroscopy, by Guido Pintacuda, Gwendal Kervern.

Fields of interestSpectroscopy/Spectrometry; Protein Structure; Spectroscopy and Microscopy



Due May 2013

2013. VIII, 198 p. Hardcover7 $259.00ISBN 978-3-642-37990-1

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Y. Yanan, University of Chicago, IL, USA

How Free Cationic Polymer Chains Promote Gene TransfectionIn this PhD thesis, Yue Yanan addresses a long-overlooked and critical question in the develop-ment of non-viral vectors for gene delivery. The author determines that those uncomplexed and cationic polymer chains free in the solution mix-ture of polymer and DNA facilitate and promote gene transfection.

Features 7 Nominated as an outstanding Ph.D. thesis by the Chinese University of Hong Kong 7 Ad-dresses and elucidates a critical but long overlooked question on non-viral gene deliv-ery 7 Greatly deepens our understanding of polymer-mediated gene transfection, representing a paradigm shift 7 Offers new insights into the rational design of next-generation superior poly-meric vectors for gene delivery

Contents Introduction and background.- Revisiting com-plexation between DNA and polyethylenimine: the effect of uncomplexed chains free in the solution mixture on gene transfection.- Revisit-ing complexation between DNA and polyethyl-enimine: the effect of length of free polycationic chains on gene transfection.- Quantitative com-parison of endocytosis and intracellular trafficking of DNA/polymer complexes in the absence/pres-ence of free polycationic chains.

Fields of interestPolymer Sciences; Organic Chemistry; Nucleic Acid Chemistry



Due May 2013

2013. XVIII, 93 p. 45 illus., 38 in color. (Springer Theses) Hardcover7 $129.00ISBN 978-3-319-00335-1

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