Acute PancreatitisAcute Pancreatitisdr. Isbandiyah, SpPDdr. Isbandiyah, SpPDFK UMMFK UMM CAUSES OF ACUTE NECROTIZING CAUSES OF ACUTE NECROTIZING PANCREATITIS.PANCREATITIS.Most commonMost common Choledocholithiasis CholedocholithiasisEthanol abuse Ethanol abuse Idiopathic IdiopathicLess commonLess common Post Endoscopic retrograde cholangiopancreatography Post Endoscopic retrograde cholangiopancreatography yperlipide!iayperlipide!ia hypercalce!ia hypercalce!ia Drugs "a#athioprine, sul$ona!ides, thia#ide, !ethildopa,Drugs "a#athioprine, sul$ona!ides, thia#ide, !ethildopa, estrogen, %S&ID' estrogen, %S&ID' Pancreas di(isu! Pancreas di(isu! &bdo!inal trau!a &bdo!inal trau!aLeast commonLeast common ereditary "$a!ilial' ereditary "$a!ilial' Clinical ManifestationsClinical Manifestations&cute pancreatitis usually has a rapid &cute pancreatitis usually has a rapid onset onset &cute pancreatitis !ay be clinically &cute pancreatitis !ay be clinically !ild or se(ere!ild or se(ereMani$ested by upper abdo!inal pain, Mani$ested by upper abdo!inal pain, (o!iting, $e(er, tachycardia, (o!iting, $e(er, tachycardia, leu)ocytosis, and ele(ated seru! leu)ocytosis, and ele(ated seru! le(els o$ pancreatic en#y!esle(els o$ pancreatic en#y!es Diagnose Diagnose Clinical !ani$estationsClinical !ani$estations*ab. Finding *ab. Finding US+US+C,-scanC,-scan CLASSIFICATIONCLASSIFICATIONClassi$ications $or acute pancreatitis are Classi$ications $or acute pancreatitis are used to identi$y patients at ris) $or used to identi$y patients at ris) $or co!plications.co!plications..anson/s score is based on 00 clinical .anson/s score is based on 00 clinical signs 1ith prognostic i!portance2 3 are signs 1ith prognostic i!portance2 3 are !easured at the ti!e o$ ad!ission and !easured at the ti!e o$ ad!ission and the other 4 in the $irst 56 hours a$ter the other 4 in the $irst 56 hours a$ter ad!issionad!ission&cute Physiology and Chronic ealth E(aluation "&P&CE II' score Ransons scoreRansons score.anson/s score 78 ".anson/s criteria o$ se(erity9 at.anson/s score 78 ".anson/s criteria o$ se(erity9 at ad!ission' ad!ission' &ge :33 yr,&ge :33 yr, 1hite-cell count :04,;;;