acupuncture and manual therapy: parallels in research and clinical practice - a lecture to the iscp...
TRANSCRIPT
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Acupuncture and Manual Therapy:Parallels in Research and Clinical Practice
Mark SextonMISCP
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The Physios
Enriching our wellbeing
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Physiotherapists get people moving
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The Plan
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Nothing is,All is becoming
Lao Tzu
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Helene LangevinThomas MyersMax ZusmanLorimer Moseley
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Helene LangevinThomas MyersMax ZusmanLorimer Moseley
Mechanotransduction
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So What!
Clinical RelevanceResearch RelevanceEducation relevance
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Acupuncture - Key Principle Remote/Systemic
LocalAdjacent
Needle Grasp/De Qi
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Body-Wide Integrative System
Every Cell, Organ, System
HomeostasisLocal RepairRemote Effects
The MeridialSystem
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Meridial System and Connective Tissue
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Connective TissueSystem
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Langevin 2001
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Langevin 2001
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Connective Tissue Whorl
Langevin 2001
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Connective Tissue Whorl
Langevin 2002
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Mechanical Coupling
Langevin 2001
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Langevin and Yandow 2002
Relationship of Acupuncture Points and Connective Tissue planes
80% Points Correlate CT Plane
Points – Greater Access to CT
50% Meridian Intersections - CT Planes
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Fibroblast Response to Needling
Langevin 2004, 2006, 2010, 2011a,b,c
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Fibroblast Cell Cytoskeleton
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Cytoskeletal Tensegrity
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Fibroblast Cell Cytoskeleton
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Mechanotransduction2-D Representation : Fibroblast in ECM
Integrins
Swartzlander 2011 (ZurichMinds)
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TGFb-1
Mechanotransduction
Integrins
Swartzlander 2011 (ZurichMinds)
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Tendon tissue provides an example of cell–cell communication.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
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Tendon tissue provides an example of cell–cell communication.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
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Tendon tissue provides an example of cell–cell communication.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
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Mechanical loading stimulates protein synthesis at the cellular level.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
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Mechanical loading stimulates protein synthesis at the cellular level.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
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Mechanical loading stimulates protein synthesis at the cellular level.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
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Fibroblast Remodelling
Langevin 2006
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Fibroblast Remodelling Langevin 2006
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Fibroblast Network
Less Dense Connective Tissue
No Gap Junctions
Connexin 43 present
Langevin 2010
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Fibroblast remodelling
Nuclear processes – mRNAChemical Cascades
Fibroblast Cell – ECM Traffic
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Fibroblast Remodelling
Nuclear processes – mRNAChemical Cascades
Fibroblast Cell – ECM Traffic
Collagen SynthesisTissue Repair
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All Movement has Effect…
…and Vice-Versa
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Langevin 2001
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Langevin HM and Sherman KJ,
Pathophysiological Model for cLBPIntegrating
Connective Tissueand
Nervous System Mechanisms
Med. Hyp. 2006
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Connective Tissue
Plasticity
Pathogenic Mechanism
Langevin 2006
Neural Tissue
Plasticity
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Connective Tissue
Plasticity
Pathogenic Mechanism
Langevin 2006
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Connective Tissue
Plasticity
Pathogenic Mechanism
Langevin 2006
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Pathogenic Mechanism
Langevin 2006
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Pathogenic Mechanism
Langevin 2006
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Pathogenic Mechanism
Langevin 2006
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Pathogenic Mechanism
Langevin 2006
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MovementPostureExercise
Treatment
Tissue Pathology
Dysfunction
Direct Tissue Mechanical Stimulus
Cognitive/BehaviouralMovementTreatment
Placebo
PsychosocialGenetic
Pathogenic Mechanism – Therapeutic interventions
Langevin 2006
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The Home Straight !!
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Helene LangevinThomas MyersMax ZusmanLorimer Moseley
Mechanotransduction
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So What!
Clinical RelevanceResearch RelevanceEducation relevance
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Mechanotransduction….
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Connective TissueSystem
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Physiotherapists get people moving
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The Physios
Enriching our wellbeing
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Acupuncture and Manual Therapy:Parallels in Research and Clinical Practice
Mark SextonMISCP
Thank You!Aisling SextonMary PenderValerie ReillyRowan ManahanJudy MurphyBrona FullanErica McMullanDamian Rice
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