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ActiveFX with UltraPulse ® Encore clinical casebook The latest advancement in minimal downtime fractional laser treatments for aging skin

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Page 1: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

ActiveFX™ with UltraPulse® Encore™

clinical casebook

The latest advancement in

minimal downtime fractional laser

treatments for aging skin

Page 2: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime
Page 3: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

with UltraPulse® Encore™

ActiveFX™

The latest advancement in

minimal downtime fractional laser

treatments for aging skin

Page 4: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Fractional CO2 Laser Skin Treatments

ActiveFX™

The goal of ActiveFX fractional laser skin

treatments is simple: replace damaged skin

with new, fresh skin. Techniques for laser skin

resurfacing have made enormous advances,

allowing nearly everyone to achieve close to

flawless complexions. The primary targets of

laser skin resurfacing include:

• Fine lines and wrinkles of the face, especially around the upper lip, cheeks and forehead

• Crow’s feet around the eyes

• Pucker marks (smoker’s lines) and frown lines

• Brown spots and splotchy, uneven skin tone

• Scars, especially acne scars

ActiveFX BenefitsActiveFX treatment produces a dramatic effect

on the skin:

• Causes immediate collagen contraction

• Reduces wrinkles and fine lines, and softens deeper frown lines

• Noticeably improves skin tone and texture

• Stimulates new collagen formation and plumps the skin1

The results of CO2 treatments are dramatic and,

with proper sun protection, can last for many years.

Most effects of treatment become visible right away,

whereas others—such as new collagen formation —

build up gradually and result in continued smoothing

over time. Therefore, most people continue to show

improvement up to six months after the procedure.

Page 5: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

“fractional” columns of high-energy laser light

“bridges” of untouched skin promote healing

MaxFX, with a laser pattern that is more dense, is a deeper treatment for more severe skin damage that provides truly dramatic results.

ActiveFX, with a more open laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime.

LASER RESURFACING PATTERNS

A high-energy laser beam is applied in a fractional pattern over the surface of the treatment area, leaving areas of untouched skin to promote quicker healing.

What is an ActiveFX “Fractional” Treatment?

ActiveFX is a laser procedure performed in a

single treatment with minimal downtime, typically

4–7 days. During the procedure, a high-energy

beam of laser light interacts with the skin’s surface,

causing the upper layer to peel off and regenerate a

layer of new, healthy skin. The laser also stimulates

formation of new underlying collagen, which results

in continued improvement in skin texture over time1.

With fractional laser treatment (ActiveFX), only a

fraction of the skin’s surface is treated, leaving

small “bridges” of untouched skin. This technique

makes the healing process much faster and enables

you to get back to normal activities sooner. With a

total resurfacing (MaxFX™) the entire skin surface is

treated with the laser.

Page 6: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

How it Works

3) ActiveFX and MaxFX treatments vaporize lines, wrinkles, scars, dark spots and other irregularities, layer by layer.

4) Treatment stimulates the formation over time of new, underlying collagen1 to smooth wrinkles and provide better elasticity and support for the skin.

new collagen

AFTER TREATMENT

ActiveFXMaxFX

elastin

2) Sun damage causes clumping of collagen and elastin fibers (elastosis), and wrinkling.

collagen fibers

elastosis

SUN DAMAGED SKINHEALTHY SKIN

1) Collagen and elastin are structural elements in the skin. Elastin gives the skin its elastic qualities.

wrinkle lines

Recognized as the gold standard of laser resurfacing

systems, the UltraPulse® Encore™ CO2 laser delivers

thousands of tiny laser pulses in a spaced pattern

over the skin. Each pulse heats a column of tissue

eliminating pigment discolorations at the surface and

creating a deep zone of heating in the tissue. Unique

to the UltraPulse Encore, these zones of heating shrink

collagen in the skin immediately. In addition, deep

tissue heating stimulates collagen remodeling1,

improving the skin further over the months following

the procedure.

1 Ross E, McKinlay J, Anderson R. Why Does Carbon Dioxide Laser Resurfacing Work? Archives of Dermatology, 135:444-454, 1999.

Page 7: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

ActiveFX™ Fractional Skin Treatments

Applications

Clinical Examples

clinical examples

Page 8: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

BEFORE AFTER 1 week

PH

OTO

S:

Gle

nn D

eBia

s, D

O;

Doy

lest

own,

PA

Wrinkles

Female with periorbital wrinkles Before and 1 week after 1 ActiveFX treatment

Page 9: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Pigmentation

Female with photodamage Before and after 1 ActiveFX treatment

BEFORE

PH

OTO

S:

Mat

teo

Tret

ti C

lem

ento

ni,

MD

; M

ilan,

IT

AFTER

Page 10: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

BEFORE AFTER 4 days

PH

OTO

S:

Gle

nn D

eBia

s, D

O;

Doy

lest

own,

PA

Wrinkles

Female with wrinkles Before and 4 days after 1 ActiveFX treatment

Page 11: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

BEFORE

Pigmentation

AFTER

PH

OTO

S:

Jef

fery

M.

Ken

kel,

MD

; D

alla

s, T

X

Female with photodamage and uneven skin tone Before and after 1 ActiveFX treatment

Page 12: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

BEFORE

Sun Damage Pigmentation

AFTER

PH

OTO

S:

Mar

k K

aufm

an,

MD

; N

ew Y

ork,

NY

Female with photodamage / uneven skin tone and pigmentation Before and after 1 ActiveFX treatment

Page 13: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

BEFORE AFTER

PH

OTO

S:

Jos

eph

Nia

mtu

III,

DM

D;

Ric

hmon

d,

VA

Sun Damage Pigmentation

Female with photodamage / mottled pigmentation Before and after 1 ActiveFX treatment

Page 14: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with photodamage / mottled pigmentation Before and after 1 ActiveFX treatment

AFTER

PH

OTO

S:

Gle

nn D

eBia

s, D

O;

Doy

lest

own,

PA

BEFORE

Sun Damage Pigmentation

Page 15: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

MaxFX™ and Other Procedures

Applications

clinical examples

Page 16: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with deep wrinkles / solar elastosis Before and 12 months after 1 MaxFX treatment

BEFORE

Deep Wrinkles Sun Damage

AFTER 12 months

PH

OTO

S:

Suz

anne

L.

Kilm

er,

MD

; S

acra

men

to,

CA

Page 17: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with deep wrinkles around the mouth Before and 2 months after 1 MaxFX treatment

BEFORE

Deep Wrinkles

AFTER 2 months

PH

OTO

S:

B.

Ken

t R

emin

gton

, M

D,

FRC

P(C

); C

alga

ry,

CA

NA

DA

Page 18: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with acne scars Before and 2 months after 1 MaxFX treatment

BEFORE

Acne Scars

AFTER 2 months

PH

OTO

S:

Otá

vio

Rob

erti

Mac

edo,

MD

; S

ão P

aulo

, B

RA

ZIL

Page 19: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with keratosis Before and after treatment

BEFORE

Keratosis

AFTER

PH

OTO

S:

Jos

eph

Nia

mtu

III,

DM

D;

Ric

hmon

d,

VA

Page 20: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with excess upper eyelid skin and wrinkles Before and 2 months after laser blepharoplasty and 1 MaxFX treatment

BEFORE

Excess Eyelid Skin

AFTER 2 months

PH

OTO

S:

B.

Ken

t R

emin

gton

, M

D,

FRC

P(C

); C

alga

ry,

CA

NA

DA

Page 21: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with excess upper eyelid skin and fat pads Before and 2 months after laser blepharoplasty

BEFORE AFTER 2 months

PH

OTO

S:

B.

Ken

t R

emin

gton

, M

D,

FRC

P(C

); C

alga

ry,

CA

NA

DA

Excess Eyelid Skin Fat Pads

Page 22: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Male with seborrheic keratoses Before and 6 weeks after 1 treatment

BEFORE

Raised Spots

AFTER 6 weeks

PH

OTO

S:

B.

Ken

t R

emin

gton

, M

D,

FRC

P(C

); C

alga

ry,

CA

NA

DA

Page 23: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Female with lower eyelid syringomas and wrinkles Before and 7 weeks after 1 treatment

BEFORE

Syringomas

AFTER 7 weeks

PH

OTO

S:

B.

Ken

t R

emin

gton

, M

D,

FRC

P(C

); C

alga

ry,

CA

NA

DA

Page 24: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

Male with rhinophyma Before and after treatment

BEFORE

Rhinophyma

AFTER

PH

OTO

S:

Jos

eph

Nia

mtu

III,

DM

D;

Ric

hmon

d,

VA

Page 25: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime
Page 26: ActiveFX - Pacific Dermatology & Cosmetic Center€¦ · laser pattern, is a fractional laser treatment for dyschromia and fine lines that yields remarkable results with minimal downtime

©2008, the Lumenis Group of Companies. Lumenis, its logo, UltraPulse, Encore, ActiveFX and MaxFX are trademarks or registered trademarks of the Lumenis Group of Companies. All rights reserved. Printed in the U.S.A. 3/08

Lumenis Inc.Santa Clara, CA, USATel +1 408 764 3000 1 877 586 3647Fax +1 408 764 3999 1 800 505 1133

Lumenis (GERMANY) GmbHDreieich-Dreieichenhain, GermanyTel + 49 6103 8335 0Fax + 49 6103 8335 300

Lumenis (CHINA) Ltd.Beijing, ChinaTel + 86 10 6510 2620Fax + 86 10 6510 2621

Lumenis (JAPAN) Co. Ltd.Tokyo, Japan Tel + 81 3 5789 8300Fax + 81 3 5789 8310

AMERICAS EUROPE / MIDDLE EAST CHINA / APAC JAPAN

PB-1005410 rev B

01075M