a sensor histidine kinase coordinates cell wall architecture with cell division in bacillus subtilis...
TRANSCRIPT
A sensor histidine kinase coordinates cell wall architecture
with cell division in Bacillus subtilis
Component annotationPMID:18573169
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574549/
Simple component annotation
• Figure 1 localizes 2 proteins to the septum of B. subtilis
What proteins?
What GO term?
• “YycG and FtsZ co-localize to the septum”
• Septum can be at the cellular level or at the level of a tissue
• Qualifier: colocalizes_with
Evidence
• Experimental - Yes– Mutant – No– Based on direct
physical interaction – No
– Direct assay – Yes• IDA
Additional annotations
• Figures 2-4 include evidence for annotations that are not allowed in CACAO (protein binding)
• Figure 5 supports annotation of another protein, YycF to GO:0009295 ! Nucleoid via similar localization experiments
• Figure 6 supports other annotations