a focused guide to measuring particles in process...a focused guide to measuring particles in...
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ParticleTrack Method of Measurement
www.mt.com/ParticleTrack
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A Focused Guide to MeasuringParticles in Process
Additional ParametersIntegrate agitation, temperature and pH data to see how parameters impact particles
Don’t Forget to Weight!To get the full particle story look at the unweighted and square weighted distributions
Correct LocationAvoid poorly mixed regions of the pipeline or vessel to ensure a representative measurement
Compare with Offline MethodsTraditional particle size analyzers are designed for quality control. ParticleTrack is designed for process monitoring and optimization. Results can be compared but both are needed to deliver the best particle.
View Particles in Real TimeParticleView provides real-time microscopy images that help with data analysis and provide comprehensive understanding
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FBRM
321Chord Length (µm)
IO
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Count
The Probe: A laser is directed through rotating optics and focused to a tight
beam spot at the probe window. When light hits a particle it is reflected
back to a detector.
The Measurement: The intensity of the reflected light is analyzed over time
allowing individual particles to be counted and the distance across particles (chord
length) to be measured.
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chord length (µm)
The Chord Length Distribution (CLD): Thousands of chord lengths are counted every second and a precise distribution sensitive to changing particle size and
count is reported in real time.
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time
fine counts
coarse counts
The Trends: Mean chord length as well as counts in individual size classes can be
trended over time, allowing changing particle systems to be studied in real time
without having to take a sample.
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time
The Process: By studying how particles change as process conditions are varied, scientists can determine which process parameters will deliver particles with the
appropriate attributes.
500 RPM
400 RPM
300 RPM
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Tracking Common Particle Mechanisms
Unweighted CLDEnhanced resolution to fine particle changes
Square-Weighted CLDEnhanced resolution to coarse particle changes
TrendsTrack size and count in individual size classes
Fine Counts Coarse Counts
Mean Chord Length (µm)
Primary Nucleation/prī,merē nōō'klē-ā'shən/
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Secondary Nucleation/'sekən,derē nōō'klē-ā'shən/
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Growth/grōTH/
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Dissolution/,disə’looSH(ə)n/
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Breakage/ˈbrākij/
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Agglomeration\ə-̩ glä-mə-̍ rā-shən\
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Attrition/əˈtriSH(ə)n/
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Correct OrientationImplementation of a ParticleTrack instrument (a) flush with wall of vessel or pipeline; (b) inserted tangentially to process flow; (c) inserted perpendicular to process flow at an elbow; and (d) inserted at optimal angle (45°) relative to process flow.?45°
Mettler-Toledo AutoChem, Inc. 7075 Samuel Morse Drive Columbia, MD 21046 USA • Telephone +1 410 910 8500 • Fax +1 410 910 8600 • Email [email protected] • Internet www.mt.com/autochem • © 01/2016 Mettler-Toledo AutoChem, Inc.
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