6.4. giardia

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    GIARDIA LAMBLIA

    ( G. INTESTINALIS)

    5/19/16Even Semester 2014

    Gastro Intestinal Tract

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    5/19/16Even Semester 2014

    Host : human, monkey, rodents, dog, cat

    Caused : giardiasis

    CosmopoliteInfects nearly 2% of adults and 6% - 8%

    of children in developed countries

    orldide!" ##% of people in developing countries

    have had giardiasis!

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    Morphology 

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    Trophozoites :

    Peer shaped, rounded anteriorly

    dorsally convex and flattened ventral site withsucking disc

    size: 1 ! 1" # , with nuclei contain

      dense central karyoso$e%ave & pairs flagella arising fro$

      axone$a

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    'yst

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    oval, si$e 8 &2 '

    Have thin tough all hich the

    cytoplasm is characteristically seperated

    Have : 2 ( nuclei

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    (ife cycle

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    Pathogenesis

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    People infected )y swallowingGiardia cysts fro$ conta$inated

    food and waterIncu)ation period : 1 ! weeks

    Giardia la$)lia do not invade the

    tissue*eed on $ucous secretion

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    'linical +y$pto$s

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    )ild infection : asymptomatic

    *iarrhea ith steatorrheic type of stool

    +tomach or adominal crampspset stomach or nausea.vomiting

    *ehydration /loss of fluids0

    Chronic : malasorption syndrome ,failure of vit 1&2 asorption

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    Histopathology

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    iagnosis

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    *etection of :tropho$oites in diarrheic stool or

    duodenal aspiration

    Cyst in formed stool

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    Giardia trophozoites stained with trichro$e- 'redit: .ater)orne isease Prevention /ranch, ''

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    0pide$iology 

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    elated to individual hygiene andenviron$ent sanitation

    Typically $ore prevalent in children-Greater risk are : traveler

    2)ackpackers3, $en who have sex

     with $en%ealth education play an i$portant

    role