6.4. giardia
TRANSCRIPT
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GIARDIA LAMBLIA
( G. INTESTINALIS)
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Gastro Intestinal Tract
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Host : human, monkey, rodents, dog, cat
Caused : giardiasis
CosmopoliteInfects nearly 2% of adults and 6% - 8%
of children in developed countries
orldide!" ##% of people in developing countries
have had giardiasis!
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Morphology
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Trophozoites :
Peer shaped, rounded anteriorly
dorsally convex and flattened ventral site withsucking disc
size: 1 ! 1" # , with nuclei contain
dense central karyoso$e%ave & pairs flagella arising fro$
axone$a
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'yst
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oval, si$e 8 &2 '
Have thin tough all hich the
cytoplasm is characteristically seperated
Have : 2 ( nuclei
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(ife cycle
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Pathogenesis
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People infected )y swallowingGiardia cysts fro$ conta$inated
food and waterIncu)ation period : 1 ! weeks
Giardia la$)lia do not invade the
tissue*eed on $ucous secretion
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'linical +y$pto$s
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)ild infection : asymptomatic
*iarrhea ith steatorrheic type of stool
+tomach or adominal crampspset stomach or nausea.vomiting
*ehydration /loss of fluids0
Chronic : malasorption syndrome ,failure of vit 1&2 asorption
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Histopathology
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iagnosis
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*etection of :tropho$oites in diarrheic stool or
duodenal aspiration
Cyst in formed stool
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Giardia trophozoites stained with trichro$e- 'redit: .ater)orne isease Prevention /ranch, ''
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0pide$iology
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elated to individual hygiene andenviron$ent sanitation
Typically $ore prevalent in children-Greater risk are : traveler
2)ackpackers3, $en who have sex
with $en%ealth education play an i$portant
role