Intorduction

Disclaimer!

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The (Big) data behind the brainVesna Prchkovska

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1.3 kg ping jellyConsumes 20% of total energy produced in the body and takes 2% size total size of the body100 billion neurons (15x more than total human population75% of the total brain mass is comprised of water which regulates various functions in the brain.

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but how to measure?

Micro-scaleElectron microscopyAxonal tracing??

Meso-scaleClarityBrainbowsMacro-scaleMRICTPETSPECT

Ex-vivo

In-vivo

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Rah et al. Front. Neuroanat. 2015

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but how to measure?

Micro-scaleElectron microscopyAxonal tracing??

Meso-scaleClarityBrainbowsMacro-scaleMRICTPETSPECT

Ex-vivo

In-vivo

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Important historical events~ from my subjective perspective ~

1973197519791986-1988198519912005X-RayCT imaginginventedPET imaging inventedMRI imaging inventedBirth of cognitive neuroscienceFirst diffusion MRI images publishedfMRI imaging began in human subjectsFirst macroscale connectome by Hagmann & Sporns

We are living at the casp of a golden age in neuroscience. This is the infancy of a renessanse 8

YOU know, what these people do is really very clever. They put little spies into the molecules and send radio signals to them, and they have to radio back what they are seeing.Niels Bohr(Nobel prize in Physics)

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In-vivo MRI modalitiesT1

TODO data dimension10

In-vivo MRI modalitiesDiffusion Weighted Imaging

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In-vivo MRI modalitiesDiffusion Weighted Imaging

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In-vivo MRI modalitiesfMRI

To do data information13

The Connectome

In complete analogy to the word genome. The -ome emphasizes the notion that the brain is a large and unique complex system: a network made of structural and functional connections (edges) linking specific neural units (nodes).

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The Connectome

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Open data initiatives

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Were doing a really shitty job. Its not because were not trying; it has to do with the complexity of the problemGuy Rouleau, the director of McGill Universitys Montreal Neurological Institute (MNI)

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Open data initiatives

Van Horn et al. Brain Imaging Behav. 2014

The amount of acquired neuroimaging data reported from published articles in representative isues of the journal NeuroImage has doubled every 26 months and can expect to top 20GB of purely raw data on average per study in only a few years. Amassing, curating, storing, and sharing of such data from neuroimaging archives presents a growing big data challenge.19

Open BCI project in NY which using kick started funding has produced 3D printed open source brain machine interface. You can now do neuroscience at home.20

OpenBCI: An Open Source Brain-Computer Interface For Makers

Open BCI project in NY which using kick started funding has produced 3D printed open source brain machine interface. You can now do neuroscience at home.21

If you are a brain geek this is the best time to be alive in history!Jordan Amadio, MD, co-founder of Neurolauch

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Thanks to the Mint Labs team

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We are scaling up the team !

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Open Fridays @ Mint Labs

Every last Fridayof the month

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www.mint-labs.com

v3sn4prchttps://www.facebook.com/MintLabs/v3sn4vesna@mint-labs.comhttps://es.linkedin.com/in/vesnaprckovskaContact

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Questions?

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