376 PATENT ABSTRACTS

non-retroviral derived nucleic acid sequence. Ex- amples of non-retroviral nucleic acid sequences are a neomycin resistance gene from the bacterial transposon TnS, a herpes simplex virus thymidine kinase gene and a chicken growth hor- mone gene, however, any prokaryotic or eu- karyotic nucleic acid sequence of interest may be used. Transgenic chickens have been produced whose cells contain and express a replication- defective retroviral vector nucleic acid sequence.

5165929

F U N G A L A N T K I L L E R

William Howell

The fungus, Rhizopus nigricans, can be used as an insecticide for use in killing ants in the order Hymenoptera. When this fungus is brought into or put into an ant hive, it kills the ants within a few days.

5165924

S E R U M - F R E E , C E L L - F R E E V A C C I N E E F F E C T I V E A G A I N S T

P N E U M O N I C P A S T E U R E L L O S I S IN C A T T L E

Patricia E Shewen, Bruce N Wilkie, Ontario, Canada assigned to University of Guelph

A serum-free vaccine effective against pneu- monic pasteurellosis in cattle comprising a non- toxic leukotoxin specific for ruminant leukocytes is disclosed. The leukotoxin is pre- pared in a serum-free medium from a culture of Pasteurella haemolytica. The produced leukotoxin is harvested from the culture medium upon detecting a certain stage during the logarithmic phase of the cell growth to obtain the optimum concentration of produced cytotoxin in the serum-free medium. Cattle may be treated with the vaccine to develop anti-leukotoxic im- munity to pneumonic pasterellosis.

5166196

M E T H O D F O R R E M O V I N G I M M U N O C O M P L E X E S F R O M

B L O O D

Kazuy Otsuji, Hakar Inaoka, Yasuki Honda, Kikuhiko Okamoto, Morihisa Tanaka, Tsukas Matsumoto, Koji Ijima, Jong-Chol Cyong, Ut- sunomiya, Japan assigned to Kao Corporation

A composition for curing autoimmune diseases is disclosed. The composition comprises as an ef- fective component an acidic hetero- polysaccharide which is secreted by a callus induced from a plant belonging to the genus Polianthes L. The acidic heteropolysaccharide can be prepared as a uniform product by the application of plant tissue culture methods and exhibits superior capability of removing immunocomplexes with the least side effects.

5165928

B I O L O G I C A L C O N T R O L O F P H Y T O P H T H O R A BY

G L I O C L A D I U M

Victoria Smith, Wayne F Wilcox, Gary E Har- man assigned to Cornell Research Foundation Inc

Certain strains of Trichoderma and Gliocladium protect plants against diseases caused by Phytophthora spp. when applied to root system biosphere, e.g., P. cactorum caused root rot and crown and collar rot in apple tree seedlings and P. sojae caused stem and root rot in soybeam plants.

5169770

A G R O B A C T E R I U M M E D I A T E D T R A N S F O R M A T I O N O F

G E R M I N A T I N G P L A N T S E E D S

Paula Chee, Stephen Goldman, Anne C Graves, Jerry Slightom assigned to The University of Toledo

PCT No. PCT/US88/04464 Sec. 371 Date Jun. 21, 1990 See. 102(e) Date Jun. 21, 1990 PCT Filed Dec. 16, 1988.A non-tissue culture process using Agrobacterium-mediated vectors to pro- duce transgenic plants from seeds of such plants as the common bean and soybean.