158 PATENT ABSTRACTS

4624835

M I C R O C E N T R I F U G A T I O N T U B E F O R T H E C O N C E N T R A T I O N O F

S A M P L E S F O R E L E C T R O N M I C R O S C O P Y

Charles P Davis, Robert Outenreath assigned to Board of Regents The University of Texas Sys- tem

A microcentrifugation tube for the preparation of a sample for examination under an electron microscope is disclosed. The tube has a bore ex- tending from the top ofrhe tube to the base of the tube. The bore includes an upper section com- prising inner walls which taper conically inwardly toward the base of the tube at an in- cluded angle of less than 25 degrees and a lower tip extending from the lower end of the upper section to the base of the tube, wherein the lower tip has a cross-sectional shape sized to ac- commodate the slicing of such a sample on a microtome when removed from the tube.

4624915

P O S I T I V E S E L E C T I O N S O R T I N G O F C E L L S

Melvin Schindler, John Holland assigned to Board of Trustees of Michigan State University

A method and apparatus for position selection of viable cells based upon differing chemical or physical properties or dynamic processes using a focussed radiant energy beam, such as a laser beam (11) to kill unwanted cells or to isolate wanted cells is described. The apparatus includes microscope means (14) and cell detection means (27) for identifying the cells to be killed or saved and attenuator means (12) for modifying the beam to prevent destruction of cells to be saved.

4624924

N O V E L C O L L A G E N A S E D I S C O L Y S I N A N D P R O D U C T I O N

M E T H O D T H E R E O F

Akira Endo. Tokyo, Japan assigned to Kabushiki Kaisha Yakult Honsha

Disclosed herein is a novel collagenase dis- colysin . It is useful for biochemical researches and the treatment of many diseases caused by collagen, such as hernia of intervertebral disc. It can be produced by culturing a discolysin- producing bacterium belonging to genus of Streptomyces in a culture medium and then col- lecting discolysin from the culture medium.

4628029

M E T H O D F O R T H E C O N V E R S I O N O F A C E L L U L O S I C S U B S T R A T E T O G L U C O S E U S I N G

M I C R O B I S P O R A B I S P O R A , S T R A I N R U T G E R S P & W

Douglas E Eveleigh. Clarence R Waldron, Timoth Bartley assigned to Parsons & Whit- temore Inc

A method is described for the enzymatic sac- charification of a cellulosic substrate to glucose which utilizes fermentation of the substrate with the cellulase enzyme complex-producing, thermophilic microorganism Microbispora bi- spora Rutgers P&W and its mutants. The resistance of M. bispora Rutgers P&W cellulase to end-product inhibition enables conversion ef- ficiency superior to that of known cellulase pro- ducing microorganisms. Continued enzyme activity at elevated temperatures allows broader applicability of enzyme-catalyzed saccharifica- tion than heretofore attained. The micro- organism in its purified form incubated on cellulase, and its cellulolytic mutants, are also disclosed.

4628035

I M M U N O A S S A Y M E T H O D

Daiz Tokinaga, Teruaki Kobayashi, Kazumichi Imai, Hachioji. Japan assigned to Hitachi Ltd

An immunoassay method for measuring a con- centration of an antigen for a short period of time by immobilizing an antibody over the whole zone of an effective supporting matrix for elec- trophoresis and fixing an antigen in a sample to be measured by electrophoresis for the antigen- antibody reaction between said immobilized antibody and said antigen.

~ 2 9 ~ 6

A P P A R A T U S F O R D E L I V E R I N G A C O N T R O L L E D D O S A G E O F A

C H E M I C A L S U B S T A N C E

Micheal L Gruenberg assigned to Endotronics Inc

An apparatus is disclosed which delivers a dosage of a chemical substance preferably to a biological tissue in such a controlled manner that the concentration affecting the biological tissue is known at each and every point in time. The ap- paratus includes a plurality of vessels with each vessel containing a different concentration of the