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PATENT ABSTRACTS

I S O L A T I O N O F C H E M I C A L L Y U N S T A B L E A N T I B I O T I C S F R O M

F E R M E N T A T I O N S O L U T I O N S

Gerhard Huber, Pete Schindler, Kelkheim, Federal Republic Of Germany assigned to Hoechst Aktiengesellscha ft

A method for isolating a chemically unstable carbapenum antibiotic from a fermentation solution by adsorbing the antibiotic on an ion ex- changer resin at the maximum of product forma- tion, thus converting it to a stabilized form, and then separating the resin from the fermentation solution.

4 5 2 9 6 9 7

P R O C E S S F O R P R O D U C I N G L - G L U T A M I C A C I D B Y

F E R M E N T A T I O N

Minoru Yoshimura, Yosuke Koyama, Koichi Goto, Sumio Inoue, Shigeho Ikeda, Hiroe Yoshii, Kawasaki, Japan assigned to Ajinomoto Co Inc

A process for producing L-glutamic acid by fer- mentation is disclosed, which process comprises culturing aerobically in a culture medium a mutant of the genus Brevibacterium or Corynebacterium which has an increased super- oxide dismutase activity and is capable of pro- ducing L-glutamic acid in the culture medium and recovering the L-glutamic acid. The yield of L-glutamic acid can be increased by using the af- orementioned mutants.