3. status of the institute: ugc recognised 12(b) & 2(f...

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PROFORMA – X PROFORMA FOR SUBMISSION OF PROJECT PROPOSAL ON CREATION OF INFRASTRUCTURAL FACILITIES (To be filled by the applicant) PART I: GENERAL INFORMATION 1. Name of the Institute/University/Organization submitting the Project Proposal: SCHOOL OF LIFE SCIENCES, SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY, NANDED-431606 2. State: .MAHARASHTRA 3. Status of the Institute: UGC RECOGNISED 12(B) & 2(f) (Annexure-1) 4. Name and designation of the Executive Authority of the Institute/University forwarding the application: Dr S B Nimse, Vice Chancellor. 5. Project Title: UPGRADATION AND STRENGTHENING OF TEACHING & RESEARCH FACILITIES FOR BIOINFORMATICS, MOLECULAR BIOLOGY, AND CELL CULTURE TECHNOLOGY IN LIFE SCIENCES 6. Specific Area: Infrastructure Facilities 7. Duration: .5 Years 8. Total Cost (Rs.): 604.55 Lakhs 9. Project Summary (Not to exceed one page. Please use separate sheet) ANNEXURE-2 A-PDF OFFICE TO PDF DEMO: Purchase from www.A-PDF.com to remove the watermark

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Page 1: 3. Status of the Institute: UGC RECOGNISED 12(B) & 2(f ...dbtepromis.gov.in/Documents/TechnicalDetails...PART III : TECHNICAL DETAILS OF PROJECT (Under the following heads on separate

PROFORMA – X

PROFORMA FOR SUBMISSION OF PROJECT PROPOSAL ON CREATION

OF

INFRASTRUCTURAL FACILITIES

(To be filled by the applicant)

PART I: GENERAL INFORMATION

1. Name of the Institute/University/Organization submitting the Project Proposal:

SCHOOL OF LIFE SCIENCES, SWAMI RAMANAND TEERTH MARATHWADA

UNIVERSITY, NANDED-431606

2. State: .MAHARASHTRA

3. Status of the Institute: UGC RECOGNISED 12(B) & 2(f) (Annexure-1)

4. Name and designation of the Executive Authority of the Institute/University

forwarding the application: Dr S B Nimse, Vice Chancellor.

5. Project Title: UPGRADATION AND STRENGTHENING OF TEACHING &

RESEARCH FACILITIES FOR BIOINFORMATICS, MOLECULAR BIOLOGY,

AND CELL CULTURE TECHNOLOGY IN LIFE SCIENCES

6. Specific Area: Infrastructure Facilities

7. Duration: .5 Years

8. Total Cost (Rs.): 604.55 Lakhs

9. Project Summary (Not to exceed one page. Please use separate sheet)

ANNEXURE-2

A-PDF OFFICE TO PDF DEMO: Purchase from www.A-PDF.com to remove the watermark

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PART II:

PARTICULARS OF COORDINATORS (INVESTIGATORS)

10. Name: Dr G Gyananath

Date of Birth: 05.12.1958............ Sex (M/F): MALE.

Indicate whether Principal Investigator:.Dr G.Gyananath

Designation : Professor.& Director

Department : School of Life Sciences

University : SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY

Address: VISHNUPURI, NANDED -431606.

PIN: 431606.

Telephone: 02462-229573.............. Telex: .........…............... Fax:..02462-229245

E-mail: [email protected]

11. Name: Professor T A Kadam

Date of Birth: 01.06.1967.................................................Sex (M/F): MALE.

Co-Investigator

Designation: Professor & Head, Microbiology, School of Life Sciences Nanded 431

606

University: SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY

Address: Vishnupuri, Nanded

PIN: 431606.

Telephone: 02462-229573...... Telex: .............................. Fax:………..

E-mail: [email protected]

12. Name: .Dr R N Gacche,

Date of Birth: .01-05-1970.....................................

Sex(M/F) : .KALE ...........................

Indicate whether Co-Investigator: Co-Investigator

Designation: Associate Professor

Department: .Head, Botany

University :. SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY

Address : Vishnupuri, Nanded

PIN : 431606….........Telephone : .02462-229242....... Telex : ...………......................

Fax ..............…......... e-mail : [email protected]..…………............................

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13. Name: .Dr B S Surwase,

Date of Birth: 12.1.1971... Sex (M/F) : MALE

Indicate whether Co-Investigator: Co-Investigator

Designation: Associate Professor

Department: .Coordinator, M. Sc. Integrated Biotechnology

University:. SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY

Address: Vishnupuri, Nanded

PIN : 431 606..............….........Telephone : .02462-229242 ext 173....... Telex:

Fax ..............…......... e-mail: [email protected]

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PART III : TECHNICAL DETAILS OF PROJECT

(Under the following heads on separate sheets)

14. Introduction (not to exceed 2 pages)

14.1 ORIGIN OF THE PROPOSAL

Life science and biotechnology have become a top priority in research and

development in many countries. Rapid advances in genetics and molecular biology and

their combination with chemical engineering and new information technologies are

having a lasting impact on a variety of economic sectors, including healthcare,

pharmaceuticals, industrial processing and agro-production. The impact of the progress in

the biosciences (human, plant, and animal biosciences) have led to the growth of

companies in many areas, from drug development and molecular diagnostics to

biomaterials and biocomposites, bio-fuels, and other bio-related products. Major

influences include the “omic” (metabolomic, proteomic, and genomic) and

biotechnological breakthroughs as well as the application of a wide array of information

and methodologies from diverse scientific disciplines.

The need for interdisciplinary teaching and research programs provides an

opportunity to explore new avenues to use these new technologies in Marathwada

region which consists of eight districts (Aurangabad, Nanded, Latur, Jalna, Beed,

Parbhani, Osmanabad, and Hingoli). The region accounts for 16.84% of the state's

population and is home to nearly 30% of the state's Below Poverty Line families. State

and central government is committed for improving the living standards of the people and

therefore the emphasis is more on creating the infrastructure to undertake the ongoing

programs offered considering the faculty expertise and the global changes in higher

education in Science & Technology.

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BRIEF DESCRIPTION OF ACADEMIC PROGRAMS & FACULTY PROFILE

AND RELATED ACTIVITES

In pursuit of excellence, the faculty members of the School of Life Sciences

impart teaching & research related to Animal & Plant Biology, Microbiology and

Biotechnology. The studies of molecular life processes in plants, animals and microbes,

the evolution and systematic identification and position of plants and animal ecology,

biological diversity and influence of climate, probiotics, enzymes in pharmaceutical

applications, medicinal plants, bioactive compounds, plant tissue culture, Biofertilizers,

effect of toxic compounds in aquatic ecosystems on fish and other organisms,

biodegradation of recalcitrant compounds, fungal biotechnology, Mycorrhiza, insilico

studies etc are some of the significant areas of teaching and research being done by the

faculty members in Life Sciences.

In order to manage these disparate subjects, the School of Life Sciences managed,

and operates, as a single entity. In this way it gains the unique synergies in teaching,

research and administration to such a diverse group of academics and students can offer.

In addition, the ‘School’ maintains a diversity of approaches to learning and teaching

appropriate to the particular discipline. This includes traditional lectures and tutorials,

group exercises, web-based learning materials and exposure to external lecturers from

industry and the professions as well as external visits. Similarly, the School embraces a

diversity of formative assessments including practical work and library/projects. The

School has maintained a strong practical component within its courses. The School

maintains a small IT room with a provision for 20 computers for use by students & PhD

scholars.

In order to meet the demands of the curricula of various courses offered in Life

Sciences and to strengthen the teaching and research activities in the frontier areas of Life

Sciences, the proposal is formulated to develop State of the Art Facilities for

strengthening the existing infrastructure for the revised curriculum based on Choice

Based Credit System and to evolve new research programs in Life Sciences.

Besides, the proposed infrastructure of the campus can be utilized by a large

number of institutions where disciplines like biotechnology, bioinformatics, basic

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sciences, Industrial Microbiology etc are offered at Graduate and Postgraduate level

and about 360 plus colleges affiliated to this university. Modern and specialized

facilities are needed for achieving the better results; however, the instrumentations

are expensive and not affordable at college level.

MAJOR STRENGTHS OF THE SCHOOL OF LIFE SCIENCES

One of the major strengths of this School is that the faculty members are not only

engaged in regular teaching activities using conventional teaching methods, but they are

actively involved in research activities. Considering the research outcome and

publications and the range of activities being pursued, the ‘School’, in a short span is

awarded with UGC-SAP (DRS-1), DST-FIST and UGC-Non-SAP for meritorious

students.

There are 13 faculty members on regular appointment and 4 teaching associates

who are actively engaged in guiding 60 plus research students for M.Sc

dissertation/project work and M.Phil & Ph.D programs. A reasonable number of students

are also recipients of fellowships from various funding agencies (DST/UGC/ICMR/Rajiv

Gandhi /Inspire, Women’s Scientist etc). Several students have qualified

GATE/SET/NET examinations and are absorbed in different institutions.

We have also organized a number of National Seminars/conferences/workshops.

Some of the listed research projects in different areas that are being pursued by the

faculty members are given in Table-1. However, for enhancing competency and

development in niche areas and to focus our research in emerging areas & new academic

programs, it is necessary that we have to explore for better infrastructural facilities.

14.2: RATIONALE FOR THE ESTABLISHMENT OF INFRASTRUCTURE

FACILITY

SUPPORTED BY CITED LITERATURE

I. DEVELOPMENT OF SKILLED HUMAN RESOURCES FOR INNNOVATIVE

RESEARCH AND

INDUSTRIAL REQUIREMENTS

II. PROMOTING INTERDISCIPLINARY INTERACTION IN LIFE SCIENCES

III. TRAIN YOUNG FACULTY MEMBERS FROM THE LIFE SCIENCES DISCIPLINE

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1.0 BIOINFORMATICS

Computers and the Internet are powerful tools for learning in the classroom. They

can help students understand the subject better; they can help them collaborate more

effectively with each other, and they can support teacher-student interactions.

Technology can enable those activities. Technology can promote a more social form of

learning both inside and outside the classroom, and how technological tools can support

collaborative learning in the classroom, on the playground and in distance education

programs.

Justification for setting up of the Bioinformatics in School of Life Sciences at the

University:

A breakthrough in research over the last two decades in the Molecular Biology,

Physiology and Biochemistry of living organisms, developments in System Biology,

Genome Sequencing, Stem Cell Biology, R & D has led to a number of sequences

deposited in the NA data bases and plethora of protein structures and sequences available

in public domain. This huge information now can be rationally analyzed using

computational tools for the better understanding of Life Sciences.

To cope up with new biology, practitioners of biosciences require enhanced skills in

mathematics, computing, and statistical analysis. There is a rapid expansion in

bioinformatics and the provision of postgraduate bioinformatics education is necessary.

At present out of 360 plus colleges affiliated to SRTM University, only two colleges

provide M.Sc. Bioinformatics. The faculty has fairly good knowledge in using the

bioinformatics tools for teaching and research. Besides, a paper on Biostatistics and

Bioinformatics is introduced in the syllabus as per the UGC guidelines. Development and

setting up bioinformatics laboratory on the campus would cater to the needs of entire

region in terms of:

• Training/ workshops & extension activities

• Curriculum development/teaching modules

• Research Exposure in bioinformatics

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JUSTIFICATION FOR COMPUTATIONAL FACILITIES (NON-RECURRING): The DELL &

Silicon Graphics® Octane® system helps to take full advantage of its advanced graphics,

CPU, and I/O subsystems by providing system architecture with low latency and high

bandwidth. As bioinformatics sequence analysis and Molecular Modelling require high end

configured systems, the SGI Octane will help, researchers across India to perform their

calculations. The facility will be open for all the academicians to use these high end systems.

Pentium IV PC’s are required for the students of the university to perform their daily lab

schedules. The KVP Numeric UPS are required to backup power supply for all the systems.

Laser Printers are used to take print out for necessary documents during the period of

projects and seminars that are to be conducted.

Justification for Softwares: SOFTWARES REQUIRED FOR DRUG DESIGNING AND

MOLECULAR MODELING: Molegro Virtual Docker, Flex-XR, Biomed CACHE, V- Life

Sciences/MDS etc. are the versatile software’s used to perform molecular modeling

calculations and docking calculations. They are some of the best docking tools available.

Several drug designing projects and practicals could be handled using these software.

INTERNET CONNECTIVITY: The University has an Internet connectivity which is of

fiber optics/broad band. A well-established LAN can be developed.

2.0 Molecular Biology and Cell Culture Technology: Cell & Tissue Culture &

Molecular Biology is an important component of the curriculum and it is introduced as a

core paper and is also offered as special papers for Biotechnology, Zoology and Botany &

Microbiology. In-vitro methods requires the use of infrastructure for undertaking studies on

biotransformation, somatic cell hybridization, horticulture, biomarkers for testing purposes

etc. The establishment of laboratories required for basic sciences & microbial, plant and

animal biotechnology would help in imparting training in establishing cell cultures for

which the laboratory is to be equipped with complete infrastructure (Carl Zeiss Binocular

Research Microscope with phase contrast and fluorescent attachments, laminar air flows,

culture racks, sequential time, photoperiodic simulator and shakers, CO2 incubator with IR

Sensor, Lyophilizer, Thermocycler, Sonicator, Cryostat and ATP Photometer etc) for

cloning in-vitro plantlets of economic and medicinal values, micropropagation, elicitation,

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hairy root culture for conservation of economically and threatened plant species,

maintenance of cell lines etc.

This facility will be accessible to all the branches of Life Sciences and is a work

arena for performing major practicals. Currently, we have a very small and insufficient

facility to cater to teaching programs. The Animal cell culture laboratory is yet to be

realized. Besides, provision will be made to attract students in Biodiversity and

conservation through Molecular Systematics which is to be designed as a multi-user facility

to enhance biodiversity teaching, research and training by supporting the use of all types of

molecular data by faculty and students. Along with development of molecular systematics

in the 1990s, topics such as phyloinformatics, biogeography, and biosystematics, the latter

incorporating models from population genetics etc are recieving wide attention.

Developments in biology have grown fast & to keep this rapidly evolving science,

the laboratory should have Biolog's Microbial Identification and Micro-workstation

which are the easiest to use and the most powerful to apply. The development of a facility

would enable the molecular biology tools available to researchers that provide technical

support for generating preliminary results, to enhance external grant proposals, to explore

experimental protocols and for studies leading to scholarly publication. In addition, the

laboratory may support PDF and train undergraduates.

Justification:

Various practical exercises that are to be performed in cell culture &

Molecular Biology (Plant, animal and microbes) & Biotechnology laboratories

include: Preparation of plant culture media, Sterilization techniques, Inoculation of

various explants, Callus culturing of different plants species, Suspension culture,

Protoplast culture, Micropropagation, Anther culture, Callus sub-culturing, Somatic

embryogenesis, Clonal propagation, Acclimatization, Production of virus free plants,

Encapsulation technique for the production of synthetic seeds, Production of secondary

metabolites, Anatomical / histological techniques for animal & plant tissue cultured in-

vitro etc; rotary microtome/ultracryostat for sectioning of animal tissues and establish

infrastructure for advanced practicals in animal biotechnology, and development of green

house for Plant Biotechnology. This facility will meet the need of majority of the students

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who are undertaking tissue culture projects. The students will be permitted to handle the

sophisticated instruments so as to have command over their practical skills.

Isolation and estimation of protein, Enzymatic estimation of glucose in blood,

Estimation of Glycogen in liver, Determination of acid values of fat and oils,

Determination of iodine number of fats and oil, Extraction and estimation of total lipids

from seed, Separation and identification of lipid by TLC and 2-D chromatography,

Extraction of total nucleic acids from plant tissue, Estimation of DNA by Diphenylamine

method, Determination of RNA by Orcinol method, Quantitative determination and

purity checking of DNA and RNA by Spectrophotometer method, Determination of

melting temperature, base composition of DNA from thermal denaturation characteristic,

Quantitative estimation of Sodium, Potassium and Calcium by using Flame Photometer,

Estimation of ascorbic acid in lemon juice, Food analysis by chemical method, Study of

enzyme kinetics etc. Plant DNA Extraction, Plant RNA isolation, Plasmid preparation,

Phage titration, Ligation reaction, Restriction digestion, RNA purification, Genomic

DNA extraction (Bacteria), bacterial, conjugation reaction, bacterial gene expression, •

CTAB Plant DNA extraction method, DNA finger printing (RFLP), DNA Molecular size

determination, Bacterial Growth curve, Ligation Reaction, Whole blood DNA extraction,

DNA amplification by using thermocycler, Latex bead agglutination reaction,

Quantitative precipitin assay, Single and double immunodiffusion (RID,ODD),

Pregnancy test, Antibody labeling, Vidal test, Southern hybridization, SDS–PAGE,

Transformation reaction, Western blotting, RAPD, Ion Exchange Chromatography, Gel

filtration chromatography, Preparation of permanent slides from Microtome.

The School has spacious laboratories and currently is equipped with basic

instruments (Annexure - 3). In order to impart training to make the students sound

in practical skills, creating such facilities would strengthen the teaching and

research programs and other services.

15. Specific objectives:

• Provide a supportive learning environment that is friendly, informal, academically

rigorous and vocationally oriented.

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• Improve its traditional research strengths in applications of Enzymes &

Pharmaceuticals,

Pesticides and biofertilizers, Mycorrrhiza & Plant tissue culture, natural polymers

for environmental applications, animal biotechnology, Microbial diversity in

natural ecosystems, research using fungal species, insilico methods, Proteomics

etc.

• Efforts to use its research background and interactions with industry

In the pursuit of achieving these objectives, some recent initiatives designed to help

achieve these include:

• Carefully reviewing the undergraduate provision with the objective of blending

biochemistry, microbiology and biotechnology into new, multidisciplinary, health

related courses that will complement our existing specialist degrees.

• The School has restructured Second Semester classes to ensure that students

receive the very best learning experience in Soft Skills and Personality Development

that provides suitable foundation modules for all the programs offered in the ‘School’.

16. Previous experience in the field

16.1. Work already done by the Department/Institute in this field (supported by

papers published and grants received in the field):

The School of Life Sciences has a full complement of 14 sanctioned and 13

regular faculty members appointed as per the UGC norms and Government of

Maharashtra. The university has committed to promote develop teaching and research in

different disciplines of interdisciplinary nature on its campus. The awareness among

faculty members to publish research papers in peer reviewed journals and participate as

resource persons in conferences, organize events of contemporary interests suggests that

we are committed to meet the challenges of the future.

The significant research work carried out with the support of financial assistance

from funding agencies has resulted in several projects and publications after the

formation of university in September 1994 (Annexure-3, 4 & 5).

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16.2. Whether the PI has previous track record of running such facility earlier? If

yes then write details.

The PI has contributed to the development of the ‘School’ previously and the

university has issued a certificate of appreciation to this effect. Besides, the PI has a good

exposure to the research. The other faculty members also have good/rich experience in

handling different projects. Their contribution has resulted in the award of UGC-SAP,

UGC-Non-SAP, DST-FIST, ICMR and UGC-Meritorious Fellowships for promoting

research in School of Life Sciences. In addition, we also have ongoing joint research

projects with different research institutes and universities.

17. Status of the other investigators of the cluster (within and outside the

institute):

All the faculty members are actively engaged in research and few of them have

been awarded ‘Best Teacher’s Award’ and the young faculty members are recipients of

Young Scientist Award from International Bodies and they have also excelled in giving

good performance in conferences for their best research presentations. The School has

invited distinguished Scientists/Faculty from other universities/institutions.

18. List of prospective users of the facility

Sr. No Name & Address of the prospective user Likely extent of

use (in %)

1. Students, Research Scholars & Faculty Members from the

‘School’

90%

2.

All the Stake holders can undertake their project work

under this facility

90%

3.

The scope for development of such facilities is high and

can generate resources for extension activities

10%

4.

The facilities thus generated can help us to organize

training and conduct workshops

90%

19. Timelines:

Period of study Achievable targets

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12 Months

Purchase of equipments and consumables, Lab set up, recruitment of

personal, calibration of instruments and standardization of protocols,

target for achieving milestones as per the objectives will be planned

24 Months Use of infrastructure for experiments and implementation of training

programs for research scholars and college teachers as per given

justification

36 Months Organization of workshop for researchers in specified area as per

the plan

48 Months We shall plan to provide extension services to all the stakeholders

60 Months

The scheme will be reviewed and continued for sustainability

20. Timelines for making the facility financially viable

Sr. No Year Percentage sustainability (expected income)

1. 2012-13 NIL

2. 2013-14 Training twice in a year(50%):1.50 Lakhs

3. 2014-15 Workshop (50%) 1.50 Lakhs

4. 2015-16 Extension Activities: 50%

5. 2016-17 Collaborative Activities: 50%

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21. List of 5 experts in India in the proposed subject area:

Sr. No. Name Designation Address

1.

Dr. B.M. Khan

Scientist

Dr. B.M. Khan, Head, Plant Tissue

Culture Division National Chemical

Laboratory, Pune 411008.

2.

Dr. Baban Ingole

Chief

Scientist

Biological Oceanography, National

Institute of Oceanography (CSIR),

Dona Paula, Goa-403004

3.

Dr. M K Dongare

Scientist

Dr. Mohan K. Dongare, Ex Scientist,

National Chemical Laboratory, Pune

411008. Director R&D, MOJJ

ENGINEERING SYSTEMS

4.

Dr. S. B.

Chincholkar

Professor

Dr. S. B. Chincholkar, School of Life

Sciences North Maharashtra University,

Post Box No. 80, Umavi Nagar, Jalgaon

5.

Dr. Datta Madamwar

Professor

Prof. Datta Madamwar, Sardar Patel Patel

University, BRD School of Biosciences, atel

Maidan, Satellite Campus, Vadtal Road,

PB# 39, Vallabh Vidyanagar, Anand 388

120, Gujarat, India

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PART IV: BUDGET PARTICULARS

(in Rupees)

A. NON-RECURRING (E.G. EQUIPMENTS, ACCESSORIES, ETC.)

S.

No.

Item Year 1 Year

2

Year 3 Year

4

Year

5

Total

1.

2.

3.

4.

5.

6.

7.

8.

9.

Eppendorf cooling

Centrifuge &

accessories (All

disciplines) (3)

Gradient PCR &

accessories (2) (Cell

& Molecular

Biology)

Carl Zeiss

Microscope With

attachments &

Image Analysis

(Plant, nimal and

Microbiology) (2)

CO2 Incubator with

IR Sensor (2)

(Animal

Biotechnology)

Ultra-Sonicator &

accessories (All

disciplines)

Spectro-ELISA &

accessories (All

disciplines)

High throughput

DNA Sequencer

Data Analyzer (Gene

Expression)

Hybridization Oven

(Molecular Biology)

Fermentor 5L &

60.0

Lakhs

30

Lakhs

25.0

Lakhs

16.0

Lakhs

8.0

Lakhs

8.0

Lakhs

40.0

Lakhs

40.0

Lakhs

10.0

Lakhs

60.0

Lakhs

30.0

Lakhs

25.0

Lakhs

16.0

Lakhs

8.0

Lakhs

8.0

Lakhs

40.0

Lakhs

40.0

Lakhs

10.0

Lakhs

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10.

11.

12.

13.

14.

15.

16.

17.

18.

19.

20

21.

22.

accessories (Micro

& Biotech)

Inverted Microscope

& Fluorescent

accessories (4) (cell

Culture)

BIOLOG GN

Workstation &

accessories

(Microbes)

LYOPHILIZER &

accessories (All

Disciplines)

Laminar Flow &

Biosafety

Cabinets(4) (Animal,

plant)

HPLC & accessories

(Biotech)

ATP Photometer

(Microbes and

Biochem)

Ultracryostat

(cell Culture)

Sliding Microtome

(Animal)

Stabilizers 5Kva (2)

Biorad Gel

Electrophoresis (4)

(All Disciplines)

Spectro

Fluorometer

(Biochem)

30.0

Lakhs

40.0

Lakhs

10.0

Lakhs

16.0

Lakhs

8.0

Lakhs

8.0

Lakhs

10.0

Lakhs

5.0

Lakhs

12.0

Lakhs

8.0

Lakhs

8.0

Lakhs

20

Lakhs

7 Lakhs

30.0

Lakhs

40.0

Lakhs

10.0

Lakhs

16.0

Lakhs

8.0

Lakhs

8.0

Lakhs

10.0

Lakhs

5.0

Lakhs

12.0

Lakhs

8.0

Lakhs

8.0 Lakhs

20 Lakhs

7 Lakhs

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23.

24.

25.

26.

Bioreactor (Plant,

Animal & Micro) &

accessories

Multi-Eletroporator

with cell fusion

module (Plant and

animal

cell culture & Mol.

Biol)

Four Tier

Illuminated Shakers

(Tissue Culture &

Biotech)

Gel Doc system &

accessories (Mol.

Bio.)

M edium Pressure

Liquid

Chromotography

system

Phase Contrast

Microscope and

accessories/Cell

culture

7 Lakhs

25

Lakhs

20

Lakhs

06

Lakhs

7 Lakhs

25 Lakhs

20 Lakhs

06 Lakhs

Sub-Total (A1): 477 Lakhs

COMPUTATIONAL FACILITIES REQUIRED (NON-RECURRING)

SL.

No

System

System Specifications

Operating system

Quantity

in number

Cost in Rupees

1 SGI - Octane

MIPS® RISC

R12000™ 270 MHz

2GB RAM

IRIX

1x4,00,000 4,00,000

2 HP Z 600 PC with

accessories

Dual Xenon 8GB RAM,

1TB HDD

SATA13.33MHz 1 GB

Graphics

Linux, Windows 5x2,20,000

11,00,000

3 HP Z 210 CMT Core 15/ MB 4 GB

RAM, 1TB HDD

SATA13.33MHz 1 GB

Graphics

Linux, Windows 20x20,000

4,00,000

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4 5 KVA Numeric

UPS

2x3,50,000

7,00,000

Sub-Total of computational facilities: A2- Rs. 26 Lakhs+ Software 10 Lakh = 36 Lakhs

Total of A = A1 + A2 = Rs. 513 Lakhs

B. Recurring

B.1 Manpower (See guidelines at Annexure-III)

S

.

N

o

.

Po

sit

io

n

N

o.

Con

soli

date

d

Em

olu

men

ts

Y

e

ar

1

Y

ea

r

2

Y

ea

r

3

Y

ea

r

4

Y

ea

r

5

To

tal

1

.

Te

ch

nic

al

As

sis

tan

t

Rs.

9,30

0-

32,0

00

R

s.

3,

3

6,

0

0

0

R

s.

3,

36

,0

00

R

s.

3,

36

,0

00

R

s.

3,

36

,0

00

R

s.

3,

36

,0

00

Rs

.

16

,8

0,

00

0

Sub-Total (B.1) = Rs. 16.80 Lakh

B.2 Consumables

S.

No

Item

Quantity Year

1

Year

2

Year

3

Year

4

Year

5

Total

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1.0 As required

for lab work

and research

chemicals &

Glassware

including

(multi-hannel

pipettors,

micropipettes,

& tissue

culture tubes,

eppendorfs &

vials,caps,

ELISA Plates

etc

Minimum as

per

requirements

(preferably

micro-

quantities

10

lakh

5

Lakh

5

Lakh

5

Lakh

Nil Rs.25

Lakhs

Sub-Total (B.2) = 25 Lakhs

Other items Year 1 Year 2 Year 3 Year 4 Year 5 Total

B.3 Travel

15,000/- 15,000/- 15,000/- 15,000/- 15,000/- 75,000/-

B.4 Contingency

25,000/- 25,000/- 25,000/- 25,000/- NIL 1,00,000/-

B.5 Overhead Charges

40

Lakhs

40

Lakhs

B.6 Workshop/Training*

4.0

Lakh

4.0

Lakh

4.0

Lakh

NIL 8

Lakhs

Total 49.75

Lakhs

Sub-Total (B = B.1 + B.2 + B.3 +

B.4 + B.5 + B.6)

91.55

Lakhs

Grand Total (A + B) 604.55

Lakhs

Note: Please give justification for each head and sub-head separately mentioned in the

above table. (Financial Year: April – March)

* The grant for workshop/training will be released only after submission of a detailed

proposal indicating different heads of the budget, participants, duration of training etc.

Justification:

Non-recurring:

1. The equipments proposed are meant for both teaching and research activities

pursued by the faculty members. The facility is being created to support and

renders services to both the students, research scholars and all the stake holders

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from local and outside the university jurisdiction. Since we have a Choice Based

Credit System, the students can undertake projects from other programs offered in

the school. As it is evident from Table-1, some of the instruments are obsolete

and this facility would strengthen and remove the obsolescence to some extent.

2. There are no National Laboratories or Research Institutes in this region. The

university and the School of Life Sciences can be used to avail the nodal facility

for different colleges.

3. The research scholars (60 plus working in Life Sciences) working under the

faculty members can avail this facility and it is rare opportunity for them to

acquire skills in undergoing hands on training. Besides, research scholars from

affiliated colleges can also take advantage of this facility.

4. These equipments can be used even by other disciplines offere on

interdisciplinary basis from campus as we believe in interdisciplinary approach.

Recurring:

1. The different set of practical and experiments require different types of

consumables (chemicals and glasswares). Sometimes, they have to be imported to

meet the quality requirement and reproducibility. The training, hands-on or

workshops to be organized may also require individual attention and hence the

provision is made for this purpose.

2. Manpower requirements are proposed to facilitate smooth functioning of the

facility and technical assistant to be recruited would be useful in terms of

maintenance and analysis and his services may be availed to keep track of the

resources and the users.

3. Travel expenses are proposed to update the current methodologies and procuring

spare parts, attending the midterm review meetings and seminars and

presentations.

4. Contingencies would meet the emergency requirements of the various

investigators in terms of computer peripherals, antivirus, stationary, report

preparation and submission and purchase of miscellaneous items as per the

provision and guidelines.

5. Overhead charges would meet the infrastructure facilities to be provided the

university for setting up of state of art laboratories which is to be equipped as per

the lab requirements.

6. Workshops and training programs are to be organized for various stake holders

and hence the budget is proposed.

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PART V: EXISTING FACILITIES

Information on existing resources such as laboratory, manpower, equipments and other

infrastructure facilities.

Available Equipment and its Accessories (TABLE-1)

Sr.No. Name of the

equipment

accessories

Make Model Funding

Agency

Year of

Procurement

1. UV Single beam

Spectrophotometer

Busch &

Lomb

Spectronic-

20

State

Govt.

1985(Obsolete)

2. UV Double Beam

Spectrophotometer

Chemito

2500

Chemito State

Govt.

1994(Obsolete)

3. Microcentrifuge Remi CM-12 State

Govt.

1994(Obsolete)

4. Cooling Centrifuge Remi C-24 State

Govt.

1985(Obsolete)

5. Electronic Balance Shimdzu AEX-2009 State

Govt.

1994(Obsolete)

6. DeepFreezer-40 deg. Remi RQFV-10 State

Govt.

1994

7. Zoom Stereo

Microscope

Labmed SZ-70 State

Govt.

1994

8. Microscope

(Research)

Getner Biolux

CXT

State

Govt.

1994

9. Electrophoresis

system

Genei Genei State

Govt.

1994

10. Computer system Digital Pentium State

Govt.

1998(Obsolete)

11. Atomic Absorption

Spectrophotometer

Perkin-

Elmer

Analyst-100 State

Govt.

1997(Obsolete)

12. Polymerase Chain

Reaction

Perkin-

Elmer

State

Govt.

1997(Obsolete)

13. Dionex HPLC State

Govt.

1998(Obsolete)

14. Orbital Shaker Remi State

Govt.

1998

15. Water Purification

System

AIMIL State

Govt.

1997(Obsolete)

Page 23: 3. Status of the Institute: UGC RECOGNISED 12(B) & 2(f ...dbtepromis.gov.in/Documents/TechnicalDetails...PART III : TECHNICAL DETAILS OF PROJECT (Under the following heads on separate

PART VI: DECLARATION/CERTIFICATION

It is certified that:

a) the same project has not been submitted to any other agency/agencies for financial

support.

b) the emoluments for the manpower proposed are those admissible to persons of

corresponding status employed in the institute/university or as per the Ministry of

Science & Technology guidelines (Annexure-III)

c) necessary provision for the scheme/project will be made in the

Institute/University/State budget in anticipation of the sanction of the scheme/project.

d) if the project involves the utilization of genetically engineered organism, it is agreed

that we will ensure that an application will be submitted through our Institutional

Biosafety Committee and we will declare that while conducting experiments, the

Biosafety Guidelines of the Department of Biotechnology would be followed in toto.

e) if the project involves field trials/experiments/exchange of specimens, etc. we will

ensure that ethical clearances would be taken from concerned ethical

Committees/Competent authorities and the same would be conveyed to the

Department of Biotechnology before implementing the project.

f) it is agreed that any research outcome or intellectual property right(s) on the

invention(s) arising out of the project shall be taken in accordance with the

instructions issued with the approval of the Ministry of Finance, Department of

Expenditure, as contained in Annexure-V.

g) we agree to accept the terms and conditions as enclosed in Annexure-IV. The same is

signed and enclosed.

h) the institute/university agrees that the equipment, other basic facilities and such other

administrative facilities as per terms and conditions of the grant will be extended to

investigator(s) throughout the duration of the project.

i) the Institute assumes to undertake the financial and other management responsibilities

of the project.

Signature of Executive Authority

of Institute/University with seal

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Signature of Principal Investigator/Coordinator

Date:

Signature of Co-Investigator Signature of Co-

Investigator

Date: Date:

Signature of Co-Investigator

Date:

Page 25: 3. Status of the Institute: UGC RECOGNISED 12(B) & 2(f ...dbtepromis.gov.in/Documents/TechnicalDetails...PART III : TECHNICAL DETAILS OF PROJECT (Under the following heads on separate

PART VII: PROFORMA FOR BIOGRAPHICAL SKETCH OF

INVESTIGATORS (COORDINATORS)

Provide the following information for the key personnel in the order listed on PART II.

Follow this format for each person. DO NOT EXCEED THREE PAGES

Name: Dr G. Gyananath

Designation: Professor & Director

Department/Institute/University: School of Life Sciences, Swami Ramanand Teerth

Marathwada University, Nanded-431 606 (MS).

Date of Birth: December 05, 1958........... Sex (M/F).Male...... SC/ST:

Education (Post-Graduation onwards & Professional Career)

Sr.

No.

Institution

Place

Degree

Awarded

Year Field of

Study

1. Dr Babasaheb Ambedkar

Marathwada University,

Aurangabad

M.Sc. 1980 Zoology

2. Dr Babasaheb Ambedkar

Marathwada University,

Aurangabad

Ph.D 1982 Zoology

3. Dr Babasaheb Ambedkar

Marathwada University,

Aurangabad

Proficiency

Certificate

1981 French

A. Position and Honors

Position and Employment:

1983-85: Lecturer, Department of Biosciences, Deemed University, Anantapur District

(AP).

1985-90; Sr. Lecturer, Biotechnology, Post graduate Studies & Research Centre,

Nanded

1990-97; Selection Grade, Biotechnology,

1997-2005: Reader in School of Life Sciences, SRTM University, Nanded – 431 606

2005-Professor

2010 onwards: Director & Professor

Honors: Certificate of appreciation issued by the University for the Contribution to

Development of University

Professional Experience and Training relevant to the Project

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B. Publications (Numbers only):

Books: .One........... Research Papers, Reports: 45 plus.....General Articles:

Patents: .Nil ........Others (Please specify) Chapters in Books (4), Reviewed: Three

articles (WEF); Reviewer of International Journals; Books Published: 01

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PROFORMA FOR BIOGRAPHICAL SKETCH OF INVESTIGATORS

BIOGRAPHICAL SKETCH OF Dr. T. A. KADAM

1. Name : Kadam Tukaram Angadrao

2. Date of Birth : 1st June 1967

3. Designation : Professor & Head, Department of Microbiology

School of Life Sciences, S.R.T.M.University,

Vishnupuri,Nanded-431606

4. Educational Qualifications : M.Sc. SET. Ph.D.

Examination

Passed

Subject Year of

Passing

Division Name of University

awarding Degree

B.Sc. Chemistry,Botany

Microbiology

1988 IInd Marathwada University

Aurangabad.

M.Sc. Biotechnology 1990 Ist

(Merit 1st)

Marathwada University

Aurangabad

SET Microbiology Jan

1995

------- Pune University Pune.

Ph.D. Microbiology Nov

2002

-------- Dr.Babasaheb Ambedkar

Marathwada University

Aurangabad

5. Specialized area of interest : Bio-fertilizers, Biodegradation and

Pharmaceutical Microbiology

6. Teaching Experience : 17 years

7. Publications : 10

8. Paper presentation : Attended 30 National/ International Seminars/

Conferences/ Workshops

9. Research project completed : 03

10. Membership : Member, Senate,

: Member, Board of Studies in Microbiology,

: Member, Faculty of Science, S. R. T. M.

University Nanded.

11. Guidance and Supervision : Recognized Research guide of S.R.T.M.

University in Microbiology.

: Two students awarded M. Phil in Microbiology

: Four students awarded Ph.D. in Microbiology

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12. Design of new courses : Designed syllabus for B.Sc.(Optional and

Integrated), M.Sc. Biotechnology and

Microbiology courses of S.R.T.M. University,

Nanded.

BIOGRAPHICAL SKETCH OF Dr. R. N. GACCHE

Provide the following information for the key personnel in the order listed on PART II.

Follow this format for each person. DO NOT EXCEED THREE PAGES

Name: Dr. Rajesh N. Gacche

Designation: Associate Prof.

Department/Institute/

University: School of Life Sciences, S. R. T. M. University, Vishnupuri, Nanded- 431

606 (MS)

Date of Birth: 1st May 1970 Sex (M/F): Male SC/ST : SC

Education (Post-Graduation onwards & Professional Career)

Sl.

No

Degree University Year Subjects Percentage

%

1. M. Sc. …..do….. 1993 Botany 76.00,

II rank

2. Ph. D. S. R. T. M. University,

Nanded

2002 Biotechnology ………….

3. SET Pune University 1995 Life Science …………..

4. CSIR- NET

(JRF)

CSIR Delhi 1997 Life Science …………..

5. B. G. L. SRTM Uni. Nanded 2009 Law First Class

6. LL. B. SRTM Uni. Nanded 2010 Law First Class

Position and Honors

Position and Employment (Starting with the most recent employment)

Sr.

No.

Institution Place Position From (Date) To (date)

1. SRTM University Asst. Professor Sept. 1999-2006

2. SRTM University Associate Professor. Sept. 2006- till date

Honors/Awards

Professional Experience and Training relevant to the Project

1. “Best Teacher Award” of 2009 of SRTM University.

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2. Completed two major research projects (CSIR, New Delhi) involving in silico

studies

B. Publications (Numbers only):

Books : Nil Research Papers: 40, Reports : nil General articles: Nil; Patents : Nil,

Others: Nil

BIOGRAPHICAL SKETCH OF Dr. B. S. SURWASE

------------------------------------------------------------------------------------------------------------

--------

Name : Dr. B. S. Surwase

Designation : Associate Professor

Department/ Institute/ University: Swmi Ramanand Teerth Marathwada University,

Nanded 431606(MS)

Date of birth : January 12,1971.

Sex : Male

Education:

Institution

Place

Degree

Awarded

Year Field of

specialization

Shivaji University, Kolhapur. M. Sc. 1994 Botany

Mumbai University, Mumbai. Ph.D. 2000 Life Sciences

Position and Employment:

1. 1999-2003-Lecturer, School of Life Sciences, Swami Ramanand Teerth Marathwada

University, Vishnupuri, Nanded.

2. 2003-2008 -Sr Lecturer, School of Life Sciences, SRTM University, Vishnupuri,

Nanded.

3. 2008-2011-. Reader, School of Life Sciences, SRTM University, Vishnupuri,

Nanded.

4. 2011-Onwards working as an Associate Professor in the School of Life Sciences,

SRTM University, Vishnupuri, Nanded.

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5. 2011 Onwards -Acting as a Coordinator, M Sc Integrated Biotechnology, School of

Life Sciences, Swami Ramanand Teerth Marathwada University, Vishnupuri,

Nanded.

Professional Experience and Training relevant to the Project.

Projects:

Ongoing : UGC, Rajiv Gandhi Science and Technology Commission, Govt. of

Maharashtra(Co investigator). Swami Ramanand Teerth Marathwada

University, Nanded.

Completed: Science and Technology Cell, Govt. of Maharashtra and DST, New

Delhi

( Co investigator).

Publications (Numbers only):

Books ..Nil Research Papers :…10 General Articles….Nil

Patents….Nil Reviewer of International Journals ….02

Research interests : Plant tissue culture , Pharmacognosy, transformation, molecular

markers.

Membership : Life member of Indian Science Congress.

:A member of Indian Botanical Society.

:A member of Editorial Board, Online International

Interdisciplinary Research Journal ( ISSN 2249-9598).

Awards:

1. 1994-1997: Fellow of the Ministry of Environment and Forests, New Delhi at

Dept of Life Science, Mumbai University, Mumbai.

2. 1997-1998: Recipient of Mumbai University Research Grants.

3. 1997-1999: Recipient of Pandit Bhagwandin Dubey and Mrs Ramdulari Dubey

Scholarship in Science of Mumbai University.

Dr. B. S. Surwase

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