Cutaneous menifestations of systemic diseases

Presented byDr.Md. Nurul Islam

MD (Internal Medicine) 2nd part student, RMCH

Erythema nodosum

Erythema nodosum

Erythema multiforme

Erythema multiforme (Target lesion)

Pyoderma ganrenosum

``Necrobiosis lipoidica

Acanthosis nigricans (Axilla)

Acanthosis nigricans (Neck)

Vitiligo

Neurofibromatosis (Café au lait spot)

Neurofibromatosis (Lisch nodules)

Neurofibromatosis (cutaneous fibroma)

Neurofibromatosis (cutaneous fibroma)

Pretibial myxoedema

Pretibial myxoedema

Xanthomas

Xanthomas (xanthelesma)

Eruptive xanthoma

Tuberous xanthoma

Sarcoidosis (Skin sarcoid)

Gout

Dermatomyositis (nail fold talengiactasia)

Dermatomyositis

SLE

SLE (Male)

SLE (Discoid rash)

PSS

PSS

PSS (radial furrow)

PSS (sclerodactyly & digital infraction)

Generalized Pruritis

• Liver disease

• Renal disease

• Blood disease

• Thyroid disease

• HIV

• Malignancy

• Psychogenic

Sign of internal malignancy

• Dermatomyositis

• Acanthosis nigricans

• Generalized pruritis

• Superficial thrombophlebitis

• Tylosis (thickened palm / sole )

• Icthyosis (dry thick scaly skin)

• Erythroderma

Sign of internal organ failure

• Liver – generalized pruritis, pigmentation, palmar erythema, Spider naevi.

• Kidney- generalized pruritis, pigmentation.

• Pancreas- DM (necrobiosis lipoidica),

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