University of Hawaiʻi – John A. Burns School of Medicine – Hawaii Center for AIDS

2016 Update: Hawaii to Zero

HIV Cure and Prevention Efforts

The Hawaiʻi Consortium for Continuing Medical Education (HCCME) is accredited by the ACCME to provide continuing medical education for physicians. The HCCME designates this live activity for a maximum of 3.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

World AIDS Day, Honolulu, HI

Dec 1, 2016, 8AM-12:30PM

UH Kakaʻako Campus Sullivan Conference Center

Free registration at: https://goo.gl/vmN30G

This educational activity is supported by an educational grant from ViiV Healthcare

3 CME Credits

HICFA Hawaii Center for AIDS

Posted on Nov 23, 2016

2016 Update: Hawaiʻi to Zero – HIV Cure and Prevention Efforts December 1, 2016

Sullivan Conference Center, Kakaʻako Campus, University of Hawaiʻi

8:00 am – 8:30 am Registration 8:30 am – 8:45 am Welcome Cecilia Shikuma, MD, Director Hawaiʻi Center for AIDS (HICFA) Opening Statement

Jerris R. Hedges, MD, MS, MMM, Dean John A. Burns School of Medicine (JABSOM), University of Hawaiʻi (UH)

8:45 am – 9:15 am Local Initiatives in HIV Cure Research Lishomwa Ndhlovu, MD, PhD, Associate Professor Dept. of Tropical Medicine,

Medical Microbiology & Pharmacology, JABSOM, UH 9:15 am – 9:45 am Inspiration and Serendipity in HIV Research Douglas F. Nixon, MD, PhD, Chair, Dept. of Microbiology, Immunology and

Tropical Medicine, The George Washington University; Principal Investigator BELIEVE (Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral Eradication) NIH’s Martin Delaney Collaboratory program

9:45 am - 10:00 am Break 10:00 am – 10:30 am Updates in HIV Prevention & the Care Continuum Julie Dombrowski, MD, MPH, Assistant Professor, Dept. of Medicine and Allergy

& Infectious Diseases, University of Washington; Deputy Director for Clinical Services, Public Health, Seattle & King County HIV/STD Program

10:30 am – 11:00 am Doing What it Takes to Get Hawaiʻi to Zero Peter Whiticar, MA, Branch Chief, Harm Reduction Services Branch, State of

Hawaiʻi, Department of Health 11:00 am – 11:30 am Patient/Community Perspective: Leadership, Commitment, Impact Tom Sheeran, Chair, World AIDS Day Hawaiʻi Keiva Lei Keʻalohimaka Cadena, Linkage to Care Coordinator, Continuum of

Care Department, Life Foundation 11:30 am – 12:00 pm Panel Discussion, Closing Remarks Moderators:

Bruce Shiramizu, MD, Professor, Depts. of Tropical Medicine, Medical Microbiology & Pharmacology and Pediatrics, JABSOM, UH Dominic Chow, MD, PhD, MPH, Professor, Depts. of Medicine and Pediatrics, JABSOM, UH; Director, Clint Spencer Clinic

2016 Update: Hawaiʻi to Zero - HIV Cure and Prevention Efforts Speakers and Moderators

Cecilia M. Shikuma, MD Director, Hawaiʻi Center for AIDS, Professor and Edwin C. Cadman Endowed Chair, Dept. of Medicine, John A. Burns School of Medicine, University of Hawaiʻi Cecilia M. Shikuma, MD is Director of the Hawaiʻi Center for AIDS, a University of Hawaiʻi Board of Regents’ approved Center of Excellence for HIV research, training and care. She is also Professor of Medicine and the Edwin C. Cadman Endowed Chair, JABSOM, University of Hawaiʻi – Manoa (UHM). She received both her BS and MD from UHM, and completed her Infectious Disease fellowship at the Los Angeles County (LAC) – University of Southern California (USC) Medical Center. She is the recipient of numerous HIV-related research grants from the National Institute of Health to research chronic, non-infectious complications of HIV including lipodystrophy, cardiovascular disease, peripheral neuropathy and HIV-associated dementia. Jerris R. Hedges, MD, MS, MMM Dean, John A. Burns School of Medicine Professor and Barry & Virginia Weinman Endowed Chair, Dept. of Medicine, John A. Burns School of Medicine, University of Hawaiʻi Jerris R. Hedges, MD, MS, MMM received his MD and MS in Chemical Engineering from the University of Washington and a Masters in Medical Management from the Marshall School of Business, University of Southern California. Dr. Hedges became Dean of JABSOM in 2008, moving to Hawaiʻi from the internationally respected Oregon Health & Sciences University (OHSU). Dr. Hedges currently serves as Principal Investigator for the Research Centers in Minority Institutions Clinical Translational Research Grant, focusing on health disparities in Hawaiʻi.

Lishomwa Ndhlovu, MD, PhD Associate Professor, Dept. of Tropical Medicine, Medical Microbiology & Pharmacology, Investigator, Hawaiʻi Center for AIDS JABSOM, University of Hawaiʻi Lishomwa Ndhlovu, MD, PhD. After his completing medical training, he received his PhD in Immunology at the Tohoku University in Japan, and completed postdoctoral fellowship in the laboratory of Dr. Douglas Nixon at the San Francisco General Hospital - University of California, San Francisco (UCSF) before joining the faculty at the University of Hawaiʻi. He is the Principal Investigator of the Laboratory of Molecular Immunology and Infectious Diseases and his research focuses on identifying novel applications in balancing strategies to prevent, slow, or eliminate HIV infection while optimizing quality of life. He has numerous grants from the National Institutes of Health to advance these strategies in persons with early infection or after long-term antiretroviral therapy. One approach investigates a novel glycoprotein, which can reactivate and disable the HIV virus in the central nervous system, an important hiding place for HIV. His lab is also researching how to clear the virus by restoring the HIV-disabled immune system’s killing function. He and his lab intend to research and study these two approaches to cure HIV infection. Douglas F. Nixon, MD, PhD Chair and Walter G. Ross Professor of Basic Science Research Dept. of Microbiology, Immunology & Tropical Medicine School of Medicine and Health Sciences, George Washington University Douglas F. Nixon, MD, PhD, graduated with a Bachelor of Science from University College London in 1981, and he received his medical degree from Westminster Hospital Medical School, London, in 1984. He then went on to train as a pathologist and clinical virologist at the University of Oxford and received his Master’s degree in 1991 and his PhD in Immunology in 1992. During his time in Oxford, he made substantial contributions to the understanding of the newly emerged HIV. Dr. Nixon spent the following three years at a biotechnology company in New York working on vaccine development, before joining the Aaron Diamond AIDS Research Centre at the Rockefeller University in New York as a postdoctoral fellow to investigate how antiviral T cells function in pediatric HIV infection. He made several important contributions to HIV/AIDS research while there and was awarded the Elisabeth Glaser Scientist Award in 2000. He joined the Gladstone Institute of Virology and Immunology in San Francisco as an Associate Professor the same year to continue his HIV research. In 2006, Dr. Nixon

became Professor of Medicine at the University of California, San Francisco (UCSF). He also became the Associate Chief of the Division of Experimental Medicine at UCSF. In October 2013, he was recruited to The George Washington University as Chair of the Department of Microbiology, Immunology and Tropical Medicine. Dr. Nixon is the Principal Investigator of the BELIEVE HIV Cure Delaney Grant. Julie Dombrowski, MD, MPH Assistant Professor of Medicine and Allergy & Infectious Diseases, University of Washington Deputy Director for Clinical Services, Public Health, Seattle & King County HIV/STD Program Julie Dombrowski, MD, PhD is Assistant Professor, Medicine and Allergy & Infectious Diseases at the University of Washington (UW). She received her BS in Biology from the University of New Mexico, her MPH from the University of North Carolina at Chapel Hill (UNCC), and her MD from Duke University School of Medicine. She is a physician with board-certifications in Internal Medicine at UCSF and an Infectious Disease fellowship at UW. She currently practices at Harborview Medical Center. Dr. Dombrowski's research focuses on the delivery of HIV and STD clinical services as well as population-based approaches to improving the HIV care continuum. She is the Deputy Director for Clinical Services, Public Health, Seattle & King County HIV/STD Program, which is a project to improve engagement in HIV care and antiretroviral use in King County. She conducts capacity-building assistance with health departments throughout the U.S. to improve HIV prevention and care activities. Peter Whiticar, MA Branch Chief, Harm Reduction Services Branch, Hawaiʻi Department of Health Peter Whiticar, MA is Chief of the Harm Reduction Services Branch in the Hawaiʻi Department of Health. The Branch is responsible for the surveillance, prevention and care of HIV, STD and adult viral hepatitis and the medical marijuana registry program in Hawaiʻi. Mr. Whiticar has served on numerous national and regional HIV expert panels and serves as chair and board member of the National Alliance of State and Territorial AIDS Directors. He has worked internationally in HIV in India and Africa.

Tom Sheeran Chair, World AIDS Day Hawaiʻi Tom Sheeran is a Honolulu resident who has been an active HIV/AIDS community liaison in Hawaiʻi. He grew up in Hilo and Honolulu and is a retired educator. His work in HIV/AIDS advocacy includes serving as president of the People with AIDS Coalition (PWAC), as co-chair of the statewide HIV care services committee Hawaiʻi Cares, and as Vice-Chair of the Governor's Committee on HIV/AIDS. He is a 2008 Suzanne Richmond-Crum Award recipient 2008 for outstanding contributions in providing HIV/AIDS services in Hawaiʻi. His contributions include selfless efforts in chairing the World AIDS Day Committee, which has organized this annual community event in Honolulu for many years. Keiva Lei Keʻalohimaka Cadena Linkage-to-Care Coordinator, Continuum of Care Dept., Life Foundation Keiva Lei Keʻalohimaka Cadena is a proud Native Hawaiian Transgender woman who lived a bi-coastal lifestyle between Honolulu and the San Francisco Bay area through her childhood to adulthood. Keiva made Hawaiʻi her permanent home in 2006 after complications from HIV prompted her to take better care of herself and to be closer to her family and cultural roots. In 2006, Keiva became a client of Life Foundation although she had been affiliated with Life Foundation since 2001 serving as an ʻAha member of UTOPIA Hawaiʻi. Keiva Lei joined the Life Foundation staff in January 2012 and her main focus is connecting people who are newly diagnosed with HIV to medical care, case management, and social support. She also provides support to people living with HIV and their partners, including partner notifications and referrals. She facilitates weekly HIV/AIDS support groups hosted by Life Foundation and facilitates the annual PLUS Retreat. She is very passionate about the work she does and has her own personal emotional investment in linking and retaining those living with HIV into quality long-term support and care. She is a devoted Mom, Daughter, Partner and soon to be Grandmother. She has been living with HIV for 13 years.

Bruce Shiramizu, MD Professor, Depts. of Tropical Medicine, Medical Microbiology & Pharmacology and Pediatrics, Investigator, Hawaiʻi Center for AIDS John A. Burns School of Medicine, University of Hawaiʻi Bruce Shiramizu, MD, is a physician in the Clint Spencer Clinic (CSC). He received his MD from the University of Utah and trained at the National Cancer Institute, National Institutes of Health. He works with the other CSC physicians and physicians from the community in the anal cancer screening program. He oversees a clinical translational laboratory at JABSOM in research focused on HIV-associated diseases and complications.

Dominic Chow, MD, PhD, MPH Director, Clint Spencer Clinic, Professor, Department of Medicine, Clinical Professor, Dept. of Pediatrics, Investigator, Hawaiʻi Center for AIDS JABSOM, University of Hawaiʻi Dominic Chow, MD is the Medical Director of the Clint Spencer Clinic, and an Investigator at the Hawaiʻi Center For AIDS. He joined the JABSOM faculty in 2000 and completed his PhD in Clinical Research at the University of Hawaiʻi at Mānoa. Dr. Chow’s research and academic interests include the complications of HIV and antiretroviral therapy on the autonomic nervous system and cardiovascular system, as well as glucose and liver metabolism. He is board-certified in Internal Medicine and General Pediatrics, and certified in HIV Medicine through the American Academy of HIV Medicine.

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