2016 biomedical research symposium of national health...

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2016 Biomedical Research Symposium of National Health Research Institutes

-Invited Speakers- Plenary Lecture

Dr. K. Kirk Shung, University of Southern California Dr. Kuo-Chen Wei, Chang Gung University

WorkShop Dr. Ronglih Liao, Harvard Medical School Dr. Yibin Wang, University of California at Los Angeles Dr. Pei-Jer Chen, National Taiwan University

Session I (A): Cancer Research Dr. Ruey-Hwa Chen, Academia Sinica Dr. Shu-Chun Teng, National Taiwan University Dr. Ming-Shyue Lee, National Taiwan University Dr. Tze-Sing Huang, National Health Research Institutes

Session I (B): Medical Engineering Dr. Yuan Luo, National Taiwan University Dr. Jin-Jia Hu, National Cheng Kung University Dr. Wei-Li Hsu, National Taiwan University Dr. Jeff Tza-Huei Wang, Johns Hopkins University

Session II (A): Molecular Genetics and Medicine Dr. Li-Kwan Chang, National Taiwan University Dr. Kou-Juey Wu, China Medical University Dr. Yung-Ling Lee, National Taiwan University Dr. Chiou-Hwa Yuh, National Health Research Institutes

Session II (B): Neural Science Dr. Alice Y.W. Chang, National Cheng Kung University Dr. Chun-Liang Pan, National Taiwan University Dr. Jun-An Chen, Academia Sinica Dr. Wen-Hai Chou, National Health Research Institutes

Session III (A): Biomedical Science Dr. Show-Li Chen, National Taiwan University Dr. Yi-Shuian Huang, Academia Sinica Dr. Bertrand Chin-Ming Tan, Chang Gung University Dr. Tse-Hua Tan, National Health Research Institutes

Session III (B): Population Health Research Dr. Lung-Chi Chen, New York University School of Medicine Dr. Angela Yu-ChenLin, National Taiwan University Dr. Shao-Yu Tsai, National Taiwan University Dr. Shu-Li (Julie)Wang, National Health Research Institutes

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K. Kirk Shung, Ph.D.

Department of Biomedical Engineering, University of Southern California

140DRB, Los Angeles, CA 90089-1111, U.S.A.

Phone No.: 1-213-821-2653

Fax No.: 1-213-821-3897

E-mail: [email protected]

Web: http://bme.usc.edu/directory/faculty/core-faculty/k-kirk-shung/

Education

1968 B.S., Electrical Engineering, Cheng Kung University, Taiwan

1970 M.S., Electrical Engineering, University of Missouri, Columbia, U.S.A.

1975 Ph.D., Electrical Engineering, University of Washington, U.S.A.

Research and Professional Positions Held in Chronological Sequence

1979 Assistant professor, Bioengineering Program, Pennsylvania State University,

University Park, U.S.A.

1989-2002

Professor, Bioengineering Department, Pennsylvania State University,

University Park, U.S.A.

1997-present Director, NIH Resource on Medical Ultrasonic Transducer Technology, U.S.A.

2002-present Dean’s Professor, Department of Biomedical Engineering, University of

Southern California, U.S.A.

Research Interests

Ultrasonic Transducers, High Frequency Ultrasonic Imaging, Ultrasound Microbeam, and

Ultrasonic Scattering in Tissues

Major Honors and Awards

Life Fellow of IEEE

Fellow of American Institute of Ultrasound in Medicine

Founding Fellow of American Institute of Medical and Biological Engineering

1985 IEEE Engineering in Medicine and Biology Society Early Career Award

2000 Best paper award for IEEE Transactions on Ultrasonics, Ferroelectrics and

Frequency Control (UFFC)

2001 Outstanding alumnus, Cheng-Kung University

2002-2003 Distinguished lecturer for the IEEE UFFC society

2010 Holmes Pioneer Award in Basic Science, American Institute of Ultrasound in

Medicine

2011 Academic career achievement award from the IEEE Engineering in Medicine

and Biology Society

2016 IEEE Biomedical Engineering Award

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Kuo-Chen Wei, M.D.

School of Medicine, College of Medicine, Chang Gung University

No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33302, Taiwan

Phone No.: 03-3281200 ext 2412

Fax No.: 03-3285818


Web: https://www.cgmh.org.tw/doctor/1674.htm

Education

1978-1985 M.D., Chung San Memorial College, Taichung, Taiwan.


1984-1985 Rotating internship in the Chung San Memorial College, Taichung, Taiwan.

1987-1989 General surgery, Department of Surgery Chang Gung Memorial Hospital,

Taipei, Taiwan

1989-present Neurosurgery, Division of Neurosurgery Chang Gung Memorial Hospital,

Taipei, Taiwan

1999-2001 Neurosurgery, Brain Tumor Research Center, University of California, San

Francisco, U.S.A.

2004-2012 Adjunct instructor, School of Medicine, Chang Gung University, Taoyuan,

Taiwan

2012-2014 Adjunct assistant professor, School of Medicine, Chang Gung University,

Taoyuan, Taiwan

2013-present Associate professor, Chang Gung Memorial Hospital, Taoyuan, Taiwan

Research Interests

1. Neurosurgery

2. Systemic analysis of brain tumor markers

3. Development of innovate brain tumor treatment system


2014 Chien-Tien Hsu’s Cancer Research Award, The Chinese Oncology Society

2015. Academic Research Category of the 12th National Innovation Award, the

Institute for Biotechnology and Medicine Industry

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Ronglih Liao, Ph.D

Department of Medicine, Brigham and Woman's Hospital

Harvard Medical School

NRB 431, 77 Avenue Louis Pasteur, New Research Building,

Boston, MA 02115, U.S.A.

Phone No.: 1-617-525-4854

Fax No.: 1-617-525-4868


Web: http://www.hms.harvard.edu/dms/bbs/fac/Liao.php

Education

1984 BS, Chemistry, Tamkang University, Taiwan

1990 Ph.D., University of Alabama at Birmingham, U.S.A.


1992 - 2006 Instructor of Medicine, Harvard Medical School, Boston, MA, USA

1996 - 2003 Assistant Professor, Department of Medicine, Boston University School of

Medicine, Boston, MA, USA

2003 - 2006 Associate Professor, Department of Medicine, Boston University School of

Medicine, Boston, MA, USA

2005 - 2015 Associate Professor, Department of Medicine, Harvard Medical School, Boston,

MA, USA

2015 - date Professor, Department of Medicine, Harvard Medical School, Boston, MA, USA

Research Interests

1. Proteotoxicity and the development of cardiac dysfunction

2. Mechanisms regulating cardiac repair and regeneration

3. The regulation of cardiac metabolism and function


1989 First Place, Graduate Student Research Day Competition- Sigma Xi, the

University of Alabama at Birmingham Chapter

1996-2001 Minority Faculty Development Award, National Institute of Health

1997 2nd Place Faculty Award, New England Cardiovascular Research Competition

2008 Fellow of American Heart Association, American Heart Association

2015 Fellow of American Physiological Society, American Physiological Society

2016 2016 Stanley J. Sarnoff Sprit Award, Sarnoff Foundation

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Yibin Wang, Ph.D.

Department of Anesthesiology, University of California at Los Angeles

BH-569 CHS, Box 957115, Los Angeles, CA 90095-7115, U.S.A.

Phone No.: 310 206 5197

Fax No.: 310 206 5907


Web: http://www.anes.ucla.edu/~yibinwang/team.html

Education

1986 Diploma, Fudan University, Biochemistry Major, Shanghai, China

1988 Bachelor in Science, State University of New York, Biological Sciences Major,

Albany, New York

1993 Ph.D., Baylor College of Medicine, Cellular and Molecular Biology Major,

Houston, Texas


1988-1993 Research Associate. Department of Cell Biology, Baylor College of Medicine,

Houston, TX.

1994-1996 Research Associate. Department of Neurobiology, The Scripps Research

Institute, La Jolla, CA.

1996-1998 Postdoctoral Researcher. Department of Medicine, Cardiac Molecular Biology

Program, University of California, San Diego, CA.

1998-2003 Assistant Professor. Department of Physiology, University of Maryland School

of Medicine, MD.

2003-2006 Associate Professor. Departments of Anesthesiology and Medicine, University

of California, Los Angeles, CA.

2003-present Adjunct Associate Professor. Department of Physiology, University of Maryland

School of Medicine, MD.

2006-present Professor. Divisio n of Molecular Medicine, Departments of Anesthesiology,

Physiology and Medicine,

Member. Molecular Biology Institute, Cardiovascular Research Laboratories,

UCLA, CA.

2011-present Vice Chair for Research and Director, Division of Molecular Medicine,

Department of Anesthesiology, David Geffen School of Medicine, UCLA

2015-2020 Chair, Cardiovascular Theme at David Geffen School of Medicine, UCLA

Research Interests

Dr. Wang obtained his training in molecular genetics and cell biology from Baylor College of

Medicine, and conducted post-doctoral research in neurobiology and cardiovascular diseases at

The Scripps Research Institute and UC, San Diego. Since 1998, Dr. Wang’s laboratory has

focused on molecular basis of stress-induced intracellular signaling pathways, including ageing,

and their functional impact on cardiovascular physiology and diseases. Wang’s lab has

developed a number of genetic models to achieve targeted manipulation of signaling molecules

in intact animals. Dr. Wang’s lab has a particular strength in discovering novel components

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and novel interactions in stress-signal transduction pathways in mammalian cells through

biochemical, proteomic, molecular and genomic approaches. Dr. Wang’s lab has established a

broad spectrum of research capacity in cardiovascular biology, from molecular biology, cell

physiology to intact heart physiology and systems biology. Dr. Wang has been supported by NIH

grants throughout his research career and published near 160 original articles.


1985-1986 First Degree Academic Award (Fudan University).

1989-1990 Howard Hughes Medical Institute Pre-doctoral Fellowship;

1993 Student Scholarship Award (Association of Chinese American in Biosciences);

1994 Visiting Scholarship Award (Chinese Natural Science Foundation).

1997 F31 Trainee Fellowship (NIH, NHLBI Training Grant in Cardiac Hypertrophy);

1999 Grant-in-Aid (AHA Mid-Atlantic Affiliate);

2002 Finalist (Research Award of Basic Science Council, AHA);

2004 Guident Foundation Visiting Professorship (Case Western Reserve University,

Cleveland, OH)

2005-2009 Established Investigator Award of AHA;

2009-2012 Changjiang Scholar (Ministry of Education, China);

2010-present Council Member, ISHR, North American Section;

2011-present Fellow of American Heart Association (AHA, BCVS)

2011-present Leadership Council, Basic Cardiovascular Science, International Committee and

Nomination Committees (AHA, BCVS);

2016 Thomas W. Smith Memorial Lecturer, Basic Cardiovascular Council, American

Heart Association

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Pei-Jer Chen, M.D., Ph.D.

Graduate Institute of Clinical Medicine, College of Medicine

National Taiwan University

7, Chung-Shan S. Rd., Taipei, Taiwan

Phone No.: 02-2312-3456#67072

Fax No.: 02-2331-7624


Web: http://clinicalmedicine.mc.ntu.edu.tw/Introduction/faculty/

Pages/%E9%99%B3%E5%9F%B9%E5%93%B2.aspx

Education

1974-1981 M.D., Department of Medicine, College of Medicine, National Taiwan

University, Taiwan

1984-1987 Ph.D., Department of Pathology, Medical School, University of Pennsylvania,

U.S.A.


1983 ECFMG certificate

1987-1990 Resident, Department of Internal Medicine, National Taiwan University

Hospital

1991-1992 Fellow, Division of Gastroenterology and Hepatology, Department of Internal

Medicine, National Taiwan University Hospital

1992- Attending Physician, Division of Gastroenterology and Hepatology, Department

of Internal Medicine, National Taiwan University Hospital

1993- Professor of Medicine, Graduate Institute of Microbiology, Medical College,

1994- Professor of Medicine, Graduate Institute of Clinical Medicine, Medical College,

National Taiwan University, National Taiwan University

2001-2003 Director, Hepatitis Research Center, National Taiwan University Hospital

2003-2009 Director, Graduate Institute of Clinical Medicine, Medical College, National

Taiwan University

Research Interests

1. Animal models of hepatitis B and D infection and replication

2. Liver tumor related gene mutation

3. Development and clinical trials of novel treatments for hepatitis B and C

4. New strategies for liver tumor management, including combination therapy, chemo-, immune,

and gene therapy


1990-1996 Outstanding Research Award; National Science Council

1992 SCBA (Society of Chinese Bioscientists in America) Hepatitis Research Award

Science and Technology Award, Executive Yuan, Taiwan

1999 National Outstanding Research Lectureship in Biomedical Science, Academia

Sinica, Taiwan

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1997 Academic Award in Medical Science, Ministry of Education,

2000-2005 International Research Scholar of Infectious Disease, Howard Hughes Medical

Institute, US

2006 Member, Academia Sinica

Academician, Academia Sinica

2006-2009 National Chair-Professor of Medicine, Ministry of Education

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Ruey-Hwa Chen, Ph.D.

Institute of Biological Chemistry, Academia Sinica

128 Academia Road, Section 2, Nankang, Taipei 11529, Taiwan

Phone No.: 02-27855696 ext.6020

Fax No.: 02-27889759


Web: http://www.ibc.sinica.edu.tw/PI_DetailE.asp?Auto=41

Education

1979-1983 B.S., Agricultural Chemistry, National Taiwan University, Taiwan

1983-1985 M.S., Biochemistry, National Taiwan University, Taiwan

1987-1991 Ph.D., Biochemistry, Michigan State University, U.S.A.


1992-1995 Postdoctoral Fellow, University of California at San Francisco, U.S.A.

1995-1996 Assistant Biochemist, University of California at San Francisco, U.S.A.

1996-2003 Associate Professor, Institute of Molecular Medicine, College of Medicine,

National Taiwan University, Taiwan

2003-2006 Professor, Institute of Molecular Medicine, College of Medicine, National

Taiwan University, Taiwan

2006-2012 Research Fellow, Institute of Biological Chemistry, Academia Sinica, Taiwan

2011-2013 Deputy Director, Institute of Biological Chemistry, Academia Sinica, Taiwan

2012- present Distinguished Research Fellow, Institute of Biological Chemistry, Academia

Sinica, Taiwan

Research Interests

The research goal of my laboratory aims at elucidating the functions of protein ubiquitination

and deubiquitination in regulation of normal physiology, cellular stress responses, and diseases

states. Special emphasis is stressed on the dysregulation of PML tumor suppressor in cancers,

ubiquitin-mediated regulation of autophagy, and the biological functions of Cul3 ubiquitin

ligase.


1998-2003 Frontier of Research Grant Award, National Science Council

1998 Outstanding Research Award, National Science Council


2001 Outstanding Young Investigator Award, Academia Sinica



2008-2012 Academia Sinica Investigator Award, Academia Sinica

2009-2012 Outstanding Scholar Research Grant, National Science Council


2012-2015 Merit Research Award, National Science Council

2012 Outstanding Award, TienTe Lee Biomedical Foundation

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2013-2017 Academia Sinica Investigator Award, Academia Sinica

2014 TBF Chair in Biotechnology


2015 Honorary Chair Professor, China Medical University

Merit MOST Research Fellow Award, The Ministry of Science & Technology

The 59th Academic Award, The Ministry of Education

2016 Taiwan Outstanding Women in Science, Wu Chien-Shiung Education

Foundation

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Shu-Chun Teng, Ph.D.

Graduate Institute of Microbiology, College of Medicine


No. 1, Sec. 1, Ren-ai Rd., Jhongjheng District, Taipei 10051, Taiwan

Phone No.: 02-23123456 ext.88289

Fax No.: 02-23915293


Web: http://microbes.mc.ntu.edu.tw/main.php?Page=SA4B1&KeyID=

1177029584457d078f638e7&Template=teacher02.php

Education

1985-1989 B.S., Chemistry, National Taiwan University, Taiwan

1991-1996 Ph.D., Biochemistry, Rutgers University, U.S.A.


1997-2000 Visiting Research Fellow in Princeton University, U.S.A.

2000-present Assistant, Associate, and Full Professor in the National Taiwan University,

Taiwan

Research Interests

Telomere replication, Chromatin Dynamics, Cell Cycle regulation, Cancer Biology, Aging


1997 Fellow, Department of Defense, U.S. Army Breast Cancer Research

2003 Da-You Wu Memorial Award, National Science Council, Taiwan

2004 Academia Sinica Research Award for Junior Research Investigators, Taiwan

2008 Young Investigator Award, Yung Shin Tian-De Lee Medical and Pharmaceutical

Science and Technology, Taiwan

2009 NSC Excellent Scholar Award, Taiwan

2011 Blue Apricot Medical Award, Taiwan

2015 Tshong-Bing Too Memorial Lecture Award, Taiwa

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Ming-Shyue Lee, Ph.D.

Graduate Institute Of Biochemistry And Molecular Biology

College of Medicine, National Taiwan University


Phone No.: 02-23123456 ext. 88210

Fax No.: 02-23915295


Web: http://www.mc.ntu.edu.tw/department/ibmb/E/teacher_lms.html

Education

1992 B.Sc., Department Of Agricultural Chemistry, National Taiwan University, Taiwan

1994 M.S., Institute Of Biological Chemistry, National Taiwan University, Taiwan

2002 Ph.D., Department Of Biochemistry And Molecular Biology, University Of

Nebraska Medical Center, Omaha, NE


2003 Post-Doctoral Research Associate Department Of Biochemistry And Molecular

Biology, University Of Nebraska Medical Center, Omaha, NE

2003-2006 Postdoctoral Fellow Lombardi Comprehensive Cancer Center, Georgetown

University Washington, District Of Columbia.

Research Interests

Cell Surface Proteolysis Plays An Important Role In A Wide Range Of Cellular Activities

Including The Degradation Of Extracellular Matrix, Blood Coagulation, Cell Growth,

Differentiation, Adhesion, Migration, And Apoptosis. Recently, The Type II Transmembrane

Serine Proteases (TTSP) Have Received More Attentions. It Is Evidenced That Deregulation Of

The TTSPs Contributes To Many Diseases; Particularly Implicated In Tumor Growth, Invasion

And Metastasis. However, The Physiological Roles Of These Proteases And How The Errant

TTSPs Malfunction In Cancer Malignancy Are Still Unclear. Thus, It Will Be An Important

Goal To Understand The Physiological Functions Of This Group Of Proteases For Developing

Therapeutic Approaches Against Cancer And Other Diseases.

Matriptase, A Member Of The Type II Transmembrane Serine Protease Family, Is Expressed

In A Variety Of Epithelial-Derived Human Tumors Including Prostate, Breast, Colon, Stomach,

And Ovarian Carcinomas. Similar To The Matriptase Expression In Normal Tissues, Matriptase

Has Not Been Found In The Tumors Of A Stromal Fibroblast Origin. It Has Been Shown That A

Tight Correlation Among Matriptase, Its Substrate Hepatocyte Growth Factor/Scatter Factor

(HGF/SF), And The C-Met Receptor In A Cohort Of 330 Node-Negative Breast Carcinomas.

Importantly, The High Expression Level Of Matriptase, C-Met Receptor, And HAI-1 Is

Associated With Poor Patient Outcome. In Ovarian Cancer, Matriptase Protein Level Is Reduced

In Stages III And IV, Compared To Stages I And II. However, The Decrease Of HAI-1

Expression In Advanced Stage Tumors Is In A Much Greater Degree Than That Of Matriptase.

The Results Suggest That In Spite Of Decreased Expression Of Matriptase In Advanced Cancer,

An Increase Of The Matriptase-To HAI-1 Ratio May Contributes To Aberrant Matriptase

Activation In Cancer Malignancy.

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The Role That Matriptase May Play In Tumor Growth, Cell Motility, And Progression Is

Attributed To The Activation Of Its Known Substrates UPA, HGF/SF, And Possibly The

G-Protein-Coupled Receptor Protease Activated Receptor (PAR-2). Matriptase-Activated HGF

Or PAR-2 Could Promote Tumor Cell Growth And Survival Through The C-Met Receptor Or

The G-Protein-Coupled Receptor Signal Pathway. Furthermore, HGF Induces Cell Mobility And

Coordinates With The Matriptase-Activated UPA/Plasmin System To Facilitate Breast Cancer

Cell Invasion By Degrading ECM. These Data Indicate That Matriptase Could Play A Role In

Cancer Invasion And Metastasis Via Recruitment And Activation Of A Major ECM-Degrading

Protease System And A Key Cell Mobility Factor (HGF) At The Surface Of Cancer Cells.

Steroid Hormone Androgens Are Required For The Development And Maintenance Of Both

The Male Phenotype And Reproductive Organs, Including The Prostate. The Normal Prostate

Gland Depends On The Testicular Androgen And Functional Androgen Receptor (AR) To

Maintain Its Functional Integrity. In The Absence Of Androgen, The Prostate Epithelia Undergo

Apoptosis, Leading To Tissue Regression. Physiologically, Androgens Exert Their Biological

Functions Via AR. Upon Ligand Stimulation, Activated AR Enters Into The Nucleus, Binds To

Its Target Genes Via An Androgen-Response Element (ARE), Which Is Involved In Various

Cellular Activities Including Cell Proliferation And Development. In The Early Stage Of

Prostate Cancer, Androgens Are Required For The Growth Of Cancer Cells. However, In

Advanced Or Hormone-Refractory Prostate Cancer, Androgen Requirements Are Reduced Or

Eliminated, And Androgen-Dependent Prostate Cells Retain The Androgen-Independent

Phenotype. However, The Detailed Molecular Mechanisms Of Androgen Actions On Normal

Tissues And In The Development Of The Steroid Hormone-Independent Phenotype Of Human

Cancer Remain Largely Unknown.

In The Future, Our Research Focus Will Be On:

(1) To Test Whether And How Steroid Hormones Can Induce Matriptase Activation

(2) To Examine If Matripase Plays A Role In The Progression Of Human Prostate Cancer.

(3) To Analyze If Matriptase Is Also Involved In The Other Types Of Cancer Malignancy.

(4) To Delineate The Roles Of Other TTSPs In Human Cancer Development, Progression, And

Metastasis.


1999-2001 The UNMC Fellowship Or Assistantship For The Graduate Studies And

Research, UNMC

2000 The 2000 Norman & Bernice Harris Cancer Research Award, UNMC Epply

Cancer Center

2001-2002 The Presidential (Bukey) Fellowship, University Of Nebraska

2002 The 2002 Norman & Bernice Harris Cancer Research Award, UNMC Epply

Cancer Center

The Travel Award, International Conference On Prostate Cancer Research

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Tze-Sing Huang, Ph.D.

National Institute of Cancer Research, National Health Research Institutes

Phone No.: 037-246-166 ext. 31709/35139

Fax No.: 037-586463


Web: http://www.nhri.org.tw/NHRI_WEB/nhriw1001Action.do?emp_cd=950136

Education

1983-1987 B.S., Department of Plant Pathology, College of Agriculture, National Taiwan

University, Taiwan

1987-1991 Ph. D., Institute of Biochemistry, College of Medicine, National Taiwan

University, Taiwan


1991-1994 Visiting Postdoctoral Biologist, Department of Biology, University of

California, San Diego, U.S.A

1994-1995 Postdoctoral Researcher, Cancer Clinical Research Center LaboratoryInstitute of

Biomedical Sciences, Academia Sinica, Taiwan

1995-1997 Senior Postdoctoral Researcher, Cancer Research Division, National Health

Research Institutes, Taiwan

1997-2002 Assistant Investigator, Cancer Research Division, National Health Research

Institutes, Taiwan

2002-2014 Associate Investigator, National Institute of Cancer Research, National Health


2014-present Investigator, National Institute of Cancer Research, National Health Research

Institutes, Taiwan

Research Interests

Dr. Huang's research team focuses on reprogramming of tissue microenvironment for cancer

development and progression. They make many efforts on studying the roles of

tumor-associated macrophages and their related secreted proteins. Recently, they have found

that macrophage-associated secreted HSP90 could induce tumorigenic stemness in pancreatic

ductal epithelial cells through a TCF12-mediated down-regulation of miR-145 and up-regulation

of stemness-related genes including CD44, CD133, and CD326. Additionally, cell plasticity is

another interested essential element required for reprogramming tissue microenvironment.

They have also found that macrophage-associated osteopontin can induce

endothelial-to-mesenchymal transition to promote colorectal cancer progression. The

underlying mechanism is at least partly contributed by the ability of osteopontin to induce an

integrin V3PI3-KAktHIF-1 signaling axis. This signaling cascade is responsible for

osteopontin-induced TCF12 expression. TCF12 is required for endothelial-to-mesenchymal

transition by acting as a transcriptional repressor of VE-cadherin. Furthermore, they are

exploring the strategies using extracellular HSP90 and TCF12 as targets to develop novel

therapeutics against macrophage-associated cancer development and progression.

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Yuan Luo, Ph.D.

Institute of Medical Device and Imaging, College of Medicine



Phone No.: 02-23123456 ext.88736

Fax No.: 02-23957990


Web: http://optics.mc.ntu.edu.tw/zh_tw/yuanluo

Education

1992-1995 B.S., Electrical Engineering, National Chung Cheng University Taiwan

Graduated with honors, and graduated early within 3 years

1995-1997 M.S., Electrical Engineering, National Chung Cheng University, Taiwan

2004-2007 M.S., College of Optical Sciences, University of Arizona, USA

2004-2008 Ph.D., College of Optical Sciences, University of Arizona, USA

Graduate Valedictorian of the College of Optical Sciences 2008. GPA 4.0


2009-2011 Postdoctoral Associate, Mechanical Engineering, MIT, USA

2011 Visiting Scholar, Biosym Laboratory, Singapore-MIT Alliance for Research and

Technology (SMART) Centre, Singapore

2011-2015 Assistant Professor, Center for Optoelectronic Biomedicine, National Taiwan

University, Taiwan

2015-present Associate Professor, Institute of Medical Devices and Imaging, National Taiwan

University, Taiwan

Research Interests

Spatial –Spectral Microscopic Imaging.

Fast Three-Dimensional Endoscopy.

Optical Holography and Diffractive Optics

Optical Phase Imaging.

Transformation Optics for Phase-Preserved Materials


2005-2007 Scholarship for Outstanding Students Studying Abroad, Ministry of Education, Taiwan

2006 Christopher Karl Schultz Memorial Scholarship, College of Optical Sciences,

University of Arizona, USA

2006-2008 TRIF-funded Photonic Research Fellowship, Technology & Research Initiative

Funding (TRIF), College of Optical Sciences & College of Engineering,

University of Arizona, USA

2008 Outstanding Graduate Student Award, College of Optical Sciences, University of

Arizona, USA

2008 Achievement Award for Outstanding Research Assistant, Graduate and

Professional Student Council (GPSC), University of Arizona, USA

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2008 Graduate Valedictorian, College of Optical Sciences, University of Arizona, USA

2009 National Research Fellowship at MIT, National Science Council, Taiwan

2013 Paper Award, Laser Medical Foundation, Taiwan

2011

Research work on “Macroscopic invisible cloak for visible light” (published in

Physical Review Letters) was reported and highlighted in Nature/Science

News/Discovery Magazine/Materials Today. It was voted the 4th in Physics

World’s “Top 10 Breakthroughs for 2010, and also voted as the 57th of

"Top 100 Stories of 2011" by Discover Magazine

(http://physicsworld.com/cws/article/news/44618)

(http://discovermagazine.com/2012/jan-feb/57)

(http://www.nature.com/news/2010/101215/full/news.2010.678.html?s=news_rss)

(http://www.sciencenews.org/view

/feature/id/337013/title/2011_Science_News_of_the_Year_Matter_%2B_Energy)

2014 Research work on “Realt-ime 3D particle manipulation visualized using VH

gratings” was highlighted in Optical Society of America (OSA) monthly

spotlight (OSA only chooses two journal articles among its more than ten

well-know SCI international journals every month)

2015 Research work on “Fast 3D imaging in optical microscopy” was highlighted in

SPIE News Room, USA

(http://spie.org/newsroom/5670-fast-3d-imaging-in-optical-microscopy)

2016 Chen-Yuan Lee Medical Memorial Award, Taiwan

http://physicsworld.com/cws/article/news/44618)

http://discovermagazine.com/2012/jan-feb/57)

http://www.nature.com/news/2010/101215/full/news.2010.678.html?s=news_rss)

http://www.sciencenews.org/view

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Jin-Jia Hu, Ph.D.

Department of Biomedical Engineering, College of Engineering

National Cheng Kung University

No. 1, University Road, Tainan City 701, Taiwan

Phone No.: 06-2757575 ext.63421

Fax No.: 06-2343270


Web: http://myweb.ncku.edu.tw/~jjhu

Education

1994 B.S. in Chemical Engineering, National Taiwan University, Taiwan

1998 M.S. in Chemical Engineering, National Taiwan University, Taiwan

2005 Ph.D. in Biomedical Engineering, Texas A&M University, College Station, USA


1997-1998 Research Assistant, Department of Chemical Engineering, National Taiwan

University, Taiwan

1998-1999 Teaching Assistant, Department of Chemical Engineering, National Taiwan

University, Taiwan

2000-2002 Research Assistant, Department of Chemical Engineering, Texas A&M

University, College Station

2002-2005 Research Assistant, Department of Biomedical Engineering, Texas A&M

University, College Station

2006-2007 Postdoctoral Research Associate, Department of Biomedical Engineering, Texas

A&M University, College Station

2007-2008 Postdoctoral Research Associate, Department of Physiology, University of

Massachusetts Medical School, Worcester

2008-2009 Assistant Professor, Department of Mechanical Engineering, National Chiao

Tung University, Taiwan

2009-present Assistant Professor, Department of Biomedical Engineering, National Cheng

Kung University, Taiwan

Research Interests

1. Soft tissue mechanics

2. Cardiovascular mechanics

3. Vascular tissue engineering

4. Bioreactor

5. Mechao-biology

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Wei-Li Hsu, Ph.D., P.T.

School and Graduate Institute of Physical Therapy, College of Medicine


No.17, Xuzhou Rd., Zhongzheng District, Taipei City 100, Taiwan

Phone No.: 02-33668127

Fax No.: 02-33668161


Web: http://www.pt.ntu.edu.tw/weili/english.html

Education

1996-2000

2000-2002

2002-2008

B.S., Physical Therapy, National Yang-Ming University, Taiwan

M.S., Physical Therapy, National Yang-Ming University, Taiwan

Ph.D., Biomechanics and Movement Science Program, Department of Physical

Therapy, University of Delaware, Newark, Delaware, U.S.A.


2008-2009

2009-2015

2015-present

Postdoctoral Research Associate, Institute of Neuroscience, University of

Oregon, Eugene, Oregon, U.S.A.

Assistant Professor, School & Graduate Institute of Physical Therapy, College of

Medicine, National Taiwan University, Taiwan

Associate Professor, School & Graduate Institute of Physical Therapy, College

of Medicine, National Taiwan University, Taiwan

Research Interests

Dr. Hsu’s research interests are centered on gait and posture in individuals who has movement

disorders. She continues her clinical practice as a physical therapist to bridge the gap between

bench and bedside. Dr. Hsu has been involved in a number of human movement research projects

and has formulated research studies based on clinical observations. She has extensive experience

in characterizing movement patterns in patients with poor balance control. She utilized

Uncontrolled Manifold Analysis to investigate the inter-limb coordination during balance

recovery. Her research findings provide a basis for treatment of patients with sensorimotor deficits

leading to balance disorders and thereby reduces the risk of falls.


2006

2013

2015

Travel Grant for the 36th annual meeting of the Society for Neuroscience:

Department of Physical Therapy, University of Delaware, U.S.A.

Excellent Innovative Teaching Material Award (Group)

National Taiwan University Hospital, Taiwan

Outstanding Research Paper Award

Taiwanese Osteoporosis Association, Taiwan

2015 Dean Chen-Yuan Lee Memorial Medical Award

College of Medicine, National Taiwan University, Taiwan

2016 Excellent Young Scholar Award Grant

Ministry of Science and Technology, Taiwan

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Jeff Tza-Huei Wang, Ph.D.

Depts. of Mechanical Engineering & Biomedical Engineering,

Sidney Kimmel Comprehensive Cancer Center,

Institute for NanoBioTechnology,

Johns Hopkins University


Web: http://me.jhu.edu/faculty/tza-huei-jeff-wang/

Education

1992 B.S., National Taiwan University, Taiwan

1994 M.S., National Taiwan University, Taiwan

2002 Ph.D., University of California, Los Angeles, U.S.A.


2013- Professor, Johns Hopkins University

2009-2013 Associate Professor, Johns Hopkins University

2002-2008 Assistant Professor, Johns Hopkins University

1998-2002 Graduate Research Assistant, UCLA

1996-1998 Manufacturing Engineer, TSMC

1994-1996 Second Lieutenant / Maintenance Engineer, Marine Army of Taiwan, R.O.C.

Research Interests

1. BioMEMS and Microfluidics

2. Nano/Micro Scale Fabrication

3. Single Molecule Manipulation and Detection

4. Genetic and Epigenetic Biomarker


2006 CAREER Award - National Science Foundation

2007 American Society of Gene Therapy CRS Jorge Heller Award

2009 Johns Hopkins University WSE Dean’s Leadership Award

Mentor for Siebel Scholar Award (V. Bailey)

2010 Mentor for American Association for Cancer Research (AACR)

Scholar-in-Training Award (Yi Zhang)

Mentor for Siebel Scholar Award (K. Liu)

2011 Best Paper Award - The 6th Annual IEEE International Conference on

Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2011)

Best Poster Award - 5th Annual INBT NanoBio Symposium

Mentor for Thrasher Research Fund Early Career Award (Seungkung Park)

JALA Ten Award

NIST/ Lab on a Chip Art in Science Award - 2011 microTAS Conference

27

2012 Best Paper Award - The 6th IEEE International Conference on

Nano/Molecular Medicine and Engineering (IEEE NANOMED 2012)

NIST/ Lab on a Chip Art in Science Award -2012 microTAS Conference

Mentor for Siebel Scholar Award (Y. Zhang)

2013 Mentor for Burroughs Wellcome Fund Career Award (Stephanie Fraley)

JALA & JBS Art of Science Award

Mentor for Siebel Scholar Award (T. Rane)

2014 Mentor for JHU PURA Award (Polly Ma)

2015 Johns Hopkins Discovery Award

Mentor for Siebel Scholar Award (Dong Jin Shin)

2016 Best Paper Award, The 29th IEEE International Conference on Micro Electro

Mechanical Systems (MEMS 2016)

28

Li-Kwan Chang, Ph.D.

Department of Biochemical Science and Technology

College of Life Science, National Taiwan University

No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan

Phone No.: 02-33664520

Fax No.: 02-33662271


Web: http://www.bst.ntu.edu.tw/en/Facultystaff/Li-Kwan-Chang-48581752

Education

1987-1991 Bachelor, Department of Botany, National Taiwan University, Taiwan

1991-1993 Master, Institute of Botany, National Taiwan University, Taiwan

1997-2001 Doctor, Graduate Institute of Basic Medical Science, Chang Gung University, Taiwan


1994-2003 Lecturer, Kaohsiung Medical University, Taiwan

2003-2006 Assistant Professor, Kaohsiung Medical University, Taiwan

2006-2010 Assistant Professor, National Taiwan University, Taiwan

2010-2015 Associate Professor, National Taiwan University, Taiwan

2015-present Professor, National Taiwan University, Taiwan

Research Interests

Molecular Virology, Microbiology, Molecular Biology


2013 Excellent Teaching Award, National Taiwan University

29

Kou-Juey Wu, M.D., Ph.D.

Research Center for Tumor Medical Science

Institute of Biomedical Sciences, College of Medicine

China Medical University

No. 91, Hsueh-Shih Road, Taichung 40402, Taiwan

Phone No.: 04-22330114

Fax No.: 04-22337974


Web: http://webap.cmu.edu.tw/TchEportfolio/index_1/wukj

Education

1976-1983 M.D., Medicine, National Taiwan University, Taipei, Taiwan

1986-1992 Ph.D., Cell Biology, Baylor College of Medicine, Houston, TX, U.S.A.


1992-1994 Resident of Clinical Pathology, Dept. of Pathology, the University of Texas

Southwestern Medical Center, Dallas, TX, U.S.A.

1994-2000 Post-doctoral fellow, Dept. of Pathology, Columbia University, College of

Physicians and Surgeons, New York, NY, U.S.A.

2000-2003 Attending Physician, Department of Medical Genetics, National Taiwan

University Hospital, Taipei, Taiwan

2003-2006 Associate Professor, Inst. of Biochemistry & Mol. Biology, National Yang-Ming

Univ., Taipei, Taiwan

2006-2014

2014-present

Professor, Inst. of Biochemistry & Mol. Biology, National Yang-Ming Univ.,

Taipei, Taiwan

Chair Professor and Director, Research Center for Tumor Medical Science,

China Medical University, Taichung, Taiwan

Research Interests

1. Molecular Biology and Tumor Biology

2. Molecular mechanisms of epithelial-mesenchymal transition and metastasis mediated by

hypoxia/HIF-1and Twist1


2009 7th Yu-Ziang Hsu Technology Paper Award, Yu-Ziang Hsu Foundation

4th TienTe Lee Award- Outstanding (TienTe Lee Biomedical Foundation)

2010

2012

2015

Outstanding research award of National Science Council, Taiwan

Hou Chin Tui Award: Basic science-Biology

Outstanding research award of National Science Council, Taiwan

Outstanding research award of Ministry of Science and Technology, Taiwan

30

Yungling Leo Lee, M.D, Ph.D.

Institute of Epidemiology and Preventive Medicine

College of Public Health , National Taiwan University


Phone No.: 02-33668016

Fax No.: 02-23511955


Web: http://www.ibms.sinica.edu.tw/pi_webpage/blue_style2016/index.php?p_id

=86&journal_info_sysid=5010606

Education

1992~1999 M.D., National Taiwan University, Taiwan

1999~2004 Ph.D., National Cheng Kung University, Taiwan


1999~2002 Residency and Fellowship, National Taiwan University Hospital, Taiwan

2004~2005 Post-doctoral Research Fellowship, National Cheng Kung University, Taiwan

2005~2009 Assistant Professor, Department of Occupational and Environmental Medicine,

National Cheng Kung University, Taiwan

2006~2007 Post-doctoral Research Fellowship, Department of Preventive Medicine,

University of Southern California, USA

2009~2014 Assistant Professor, Institute of Epidemiology and Preventive Medicine,


2014~ Associate Professor, Institute of Epidemiology and Preventive Medicine,


2013~ Adjunct Assistant Professor, Institute of Biomedical Sciences, Academia Sinica,

Taiwan

Research Interests

Pharmacogenetics, Skin Inflammation, Glyco Medicine


2002~2004 MD-PhD Pre-doctoral Fellowship, National Health Research Institute

2006 Outstanding Asian Young Environmental Epidemiologist Award, International

Society of Environmental Epidemiology

2008 Outstanding Young Physician Award, Taiwan Environmental and Occupational

Medicine Association

2014 Ta-You Wu Memorial Award, Ministry of Science and Technology

2015 Tien-Te Lee Young Biomedical Scientist Award

31

Chiou-Hwa Yuh, Ph.D.

Institute of Molecular and Genomic Medicine

National Health Research Institutes

35, Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan

Phone No.: 037-246166 ext. 35338

Fax No.: 037-586459



Education

1983-1987 B.S., Department of Biology, Fu-Jen Catholic University, Taipei, Taiwan

1987-1992 Ph.D, Institute of Microbiology and Immunology, National Yang-Ming Medical

College, Taipei, Taiwan

1992-1995 Research Fellow, Biology Division, California Institute of Technology,

Pasadena, California, USA

1995-2001 Senior Research Fellow, Biology Division, California Institute of Technology,

Pasadena, California, USA


1996-2001 Research Associate, Division of Medical Research, Stowers Institute of Medical

Research, Missoli, USA

2001-2002 Director, Transcription Factor Center, Beckman Institute,, California Institute of

Technology, Pasadena, California, USA

2002-2004 Member of the Professional Staff, Biology Division, California Institute of

Technology, Pasadena, California, USA

2005-2015 Associate Investigator, Division of Molecular and Genomic Medicine, National

Health Research Institutes, Mialoi, Zhunan, Taiwan

2005-2006 Adjunct Assistant Professor, Institute of Bioinformatics and Structural Biology,

National Tsing Hua University, HsincChu, Taiwan

2006-2015 Adjunct Associate Professor, Institute of Bioinformatics and Structural Biology,

National Tsing Hua University, HsincChu, Taiwan

2007-2015 Joint Associate Professor, Department of the Biological Science & Technology,

National Chiao Tung University, HsincChu, Taiwan

2015-present Investigator, Division of Molecular and Genomic Medicine, National Health

Research Institutes, Mialoi, Zhunan, Taiwan

2015-present Adjunct Professor, Institute of Bioinformatics and Structural Biology, National

Tsing Hua University, HsincChu, Taiwan

2016-present Joint Professor, Department of the Biological Science & Technology, National

Chiao Tung University, HsincChu, Taiwan

Research Interests

Dr. Chiou-Hwa Yuh is a molecular biologist working on development and carcinogenesis. Dr.

Yuh is Investigator of National Health Research Institutes (NHRI), Taiwan. She has BS degree

from Biology department of Fu-Jen University, and a Ph.D. degree from the Department of

32

Microbiology and Immunology of National Yang-Ming University, Taiwan. She received her

postdoctoral training at Cal Tech and gained tremendous experience on the Systems Biology and

Genetic Regulatory Networks under the supervision of Dr. Eric Davidson from 1992-2004. She

joined NHRI at December 31 of 2004, started using zebrafish as model organism to decode the

embryonic gene regulatory networks. She initiated the systematic analysis of hepatocellular

carcinoma (HCC) in mouse model, and established transgenic zebrafish model. Dr. Yuh is

currently interested in the mechanism of ribose-5-phosphate isomerase A (RPIA) in human

hepatocellular carcinoma (HCC) and colorectal cancer. She is also studying the overexpression

of alpha-mannosidase 1A1, 1A2, and 1B1 as well as down-regulation of alpha-mannosidase 1C1

during hepatocarcinogenesis.

Dr. Yuh’s further develops the drug screening platform. In cancer research, the unanswered

questions and grand challenges are complexity of genomes and drug resistance, and long-term

drug treatment to control cancer is a major challenge. After a period of targeting therapy, in

about 2 to 3 months, eventually drug resistance occurs. From our previous patient-derived

xenograft model of colorectal cancer zebrafish personalized drug screening, Dr. Yuh found that

the drug inhibition lost along with tumor cell’s passage increases. This result prompted us to

investigate the genomic evolution of drug resistance, and test new clinical available target

therapies for the resistant tumors.


1984 - 1987 Ranked-First Scholarship Award, Fu-Jen Catholic University, Taiwan

1987 - 1992 Research Fellowship, Taiwan National Science Council, Taiwan

1991 1st among competitors of Wang Ming-Ning Scholarship, Wang Ming-Ning

Memorial Foundation, Taiwan

1993 Procter and Gamble Fellowship, California Institute of Technology, USA

1994 Gordon Ross Fellowship, California Institute of Technology, USA

1995 Biology Divisional Fellowship, California Institute of Technology, USA

2012 2012 Liver Disease Prevention Research Foundation Fellowship



33

Alice Y.W. Chang, Ph.D.

Department of Physiology, College of Medicine

National Cheng Kung University

No. 1, University Road, Tainan City 701, Taiwan

Phone No.: 06-2353535 ext.5445

Fax No.: 06-2362780


Web: http://phys.med.ncku.edu.tw/files/11-1399-17853.php?Lang=zh-tw

Education

1984-1988 B.S. Taipei Medical University, Taiwan

1991-1993 M.S. National Yang Ming University, Taiwan

1993-1998 Ph.D. National Yang Ming University, Taiwan


1998-2001 Assistant Professor, National Sun Yat-sen University, Taiwan

2001-2005 Associate Professor, National Sun Yat-sen University, Taiwan

2005-2009 Professor, National Sun Yat-sen University, Taiwan

2009-2014 Principle Investigator, Chang Gung Memorial Hospital, Taiwan

2009-2016 Joined Professor, National Sun Yat-sen University, Taiwan

2010-2015 Joined Professor, Kaohsiung Medical University, Taiwan

2014-present Professor, National Cheng Kung University, Taiwan

Research Interests

1. Investigate the mechanisms organophosphate poisoning and its potential antidote

2. Dissect the dysfunction and dysregulation of central nervous system in cardiovascular and

neurological consequences after stroke

3. Study the mechanisms of epilepsy-induced damage responses

4. Demonstrate the mechanisms of fatal drug addiction

5. Examine the important interaction between neurons and glia in neurological diseases

6. Determine the epigenetic mechanisms of esophageal squamous-cell carcinoma


1999-2001 Research Achievement Award, National Science Council, Taiwan

2001 Young Investigator Award, National Sun Yat-sen University, Taiwan

2006 Outstanding Research Award, Pharmacological Society in Taiwan, Taiwan

2007 Research Excellence Award, National Sun Yat-sen University, Taiwan

2008 Outstanding Senior Teacher, National Sun Yat-sen University, Taiwan

2009-2014 Research Award, Chang Gung Memorial Foundation

34

Chun-Liang Pan, MD, Ph.D.

Institute of Molecular Medicine, College of Medicine



Phone No.: 02-23123456 ext. 88360

Fax No.: 02-23221675


Web: http://chunliangpan.weebly.com/

Education

1989-1996 M.D., National Taiwan University, Taiwan

2003-2008 Ph.D., Neuroscience, University of California, Berkeley, USA


1998-2002 Residency, Neurology, National Taiwan University Hospital, Taiwan

2002-2003 Research assistant, Institute of Biological Chemistry, Academia Sinica, Taiwan

2008-2010 Postdoctoral Fellow, University of California, San Francisco, USA

2010-2015 Assistant professor, Institute of Molecular Medicine, National Taiwan

University, Taiwan

2015- Associate professor, Institute of Molecular Medicine, National Taiwan

University, Taiwan

Research Interests

1. Neuronal aging and neurodegenerative diseases

2. Neuronal development


2003-2006 International Graduate Fellowship, Ministry of Education, Taiwan

2015 C.-Y. Lee Memorial Medical Award, National Taiwan University College of

Medicine, Taiwan

2016 Young Scientists Prize, Tien-Te Lee Biomedical Awards

2016 Young Investigator Award, Academia Sinica

35

Jun-An Chen, Ph.D.

Institute of Molecular Biology, Academia Sinica


Phone No.: 02-27880460

Fax No.: 02-27826085


Web: http://www.imb.sinica.edu.tw/~jachen/

Education

1993-1997 BSc, Department of Chemistry, National Chung Cheng University, Taiwan.

1997-1999 MSc, Institute of Biochemical Sciences, National Taiwan University, Taiwan.

2002-2006 PhD, The Wellcome Trust Cancer Research UK Gurdon Institute, University of

Cambridge, UK.


2001-2002 Teaching Instructor, Institute of Biochemical Sciences, National Taiwan

University, Taiwan.

2002-2006 PhD student, Supervised by Dr. Enrique Amaya, The Wellcome Trust/CR UK

Gurdon Institute, University of Cambridge, UK

2007-2012 Postdoctoral Fellow, Supervised by Dr. Hynek Wichterle, Columbia University, USA.

2012-present Assistant Research Fellow, Principal Investigator, Institute of Molecular

Biology, Academia Sinica, Taiwan.

Research Interests

The focus of research in my laboratory is to elucidate how neurons establish individual identity

in the developing nervous system and why only specific neuron subtypes are vulnerable in the

neurodegenerative diseases. We tackle these questions via studying non-coding RNAs and their

roles during motor neuron generation and degeneration. My lab employs motor neurons generated

from embryonic (ES) and induced pluripotent (iPS) stem cells, as well as mouse animal models to

investigate motor neuron development and disease. I have developed and generated a series of

stem cells and animal models to study functions of microRNA by “gain-of-function” and

“loss-od-function” approaches. Besides elucidating the basic molecular mechanisms underlying

specification of neuronal diversity during CNS development, I apply the stem cell system to study

motor neuron diseases. In particular, I am engaged in the establishment and study of patient

specific iPS cell based models of Spinal Muscular Atrophy (SMA), Amyotrophic Lateral

Sclerosis (ALS). iPS cell derived motor neurons are used in my lab to perform deep sequencing

from healthy and ALS motor neurons and to functionally characterize non-coding RNA pathology

in motor neuron. I am also a core member of Neuroscience Program and RNA program in

Academia Sinica, which provides strong and solid consortium to give advices and exchange the

ideas for our projects. In summary, I have multidisciplinary approaches, from in vitro stem cells to

in vivo mouse models, to study motor neuron development and degeneration.

36


2000 Presidential Award in NCCU

2002-2005 Taiwan International PhD Scholarship

2002-2006 The Wellcome Trust Scholarship

2008-2009 Taiwan National Science Council Postdoctoral Fellowship

2012-2015 Taiwan National Science Council Talented Investigator Fellowship

37

Wen-Hai Chou, Ph.D.

Center for Neuropsychiatric Research, National Health Research Institutes

Phone No.: 037-246-166 ext. 36717

Fax No.: 037-586-453


Web: http://scholar.google.com/citations?user=plWIRMEAAAAJ&hl=en

Education

1983-1987 B.S., Entomology, National Chung-Hsing University, Taiwan.

1990-1993 M.S., Biology, Texas A&M University, College Station, Texas, USA.

1993-2000 Ph.D., Molecular Medicine, University of Texas Health Science Center, San

Antonio, Texas, USA.


2000-2001 Postdoctoral Fellow, Howard Hughes Medical Institute and Department of

Neurology, School of Medicine, University of California, Los Angeles, CA,

USA.

2001-2005 Assistant Research Scientist, Ernest Gallo Clinic & Research Center, School of

Medicine, University of California, San Francisco, CA, USA.

2005-2010 Assistant Adjunct Professor, Department of Neurology, School of Medicine,

University of California, San Francisco, CA, USA.

2010-2016 Assistant Professor, Department of Biological Sciences and School of

Biomedical Sciences, College of Arts and Sciences, Kent State University, OH,

USA.

2016-present Assistant Investigator, Center for Neuropsychiatric Research, National Health

Research Institutes, Taiwan.

Research Interests

1. Stroke

2. Neurodegeneration

3. PKC signaling


1997 Travel award for distinguish research from Institute of Biotechnology,

University of Texas Health Science Center at San Antonio, Texas, USA.

1998 Second-place outstanding research award at the Annual Retreat, Institute of

Biotechnology, University of Texas Health Science Center at San Antonio,

Texas, USA.

1998 First-place poster award at the Annual Graduate Student Association Forum,

University of Texas Health Science Center at San Antonio, Texas, USA.

2011 Elected as a Fellow of the American Heart Association (F.A.H.A.).

38

Show-Li Chen, Ph.D.

Graduate Institute of Microbiology, College of Medicine



Phone No.: 02-23123456 ext.88378

Fax No.: 02-23915293


Web: http://microbes.mc.ntu.edu.tw/main.php?Page=SN4O1&KeyID=

103588551345783a9d3c99a&Template=teacher02E.php

Education

1972-1976 BS, Entomology, National Chung-Hsing University (Taiwan).

1978-1980 MS, Medical Biology, National Defense Medical Center (Taiwan).

1985-1990 Ph.D. Molecular Virology, The Johns Hopkins University (USA).


1990-1994 Associate Professor, Dept. Microbiology and Immunology, National Defense

Medical Center, Taiwan

1994-2005 Professor and chairman, Dept. Microbiology and Immunology, National Defense

Medical Center, Taiwan

2001-2002 Visiting Scholar, Dept Pathology, The Johns Hopkins University, USA

Research Interests

HPV, Cancer Biology, Muscle Contraction, Muscle Regeneration, Neurongenesis


1988 The Frederic B. Band Award (for an outstanding research idea in the area of

Pathology, in JOHNS HOPKINS UNIVERSITY, USA).

1989 The Delta Omerga Honorary Society Alpha Chapter (in recognition of

excellence in student research, in JOHNS HOPKINS UNIVERSITY, USA).

2000 The Wu Tan-Che Award (for an outstanding research in Medical Science,

Taipei, Taiwan).

1996-2001 The National Science Council Award for recognition of outstanding research,

(Taipei, Taiwan) for three times.

2002-2008 The National Science Council Award for Distinguished Investigator for research

(Taipei, Taiwan)

2009 The National Science Council Award for Excellent and Distinguished

Investigator for research (Taipei, Taiwan)

2006-present National Taiwan University for Distinguished Professor

39

Yi-Shuian Huang, Ph.D.

Institute of Biomedical Sciences, Academia Sinica


Phone No.: 02-26523523

Fax No.: 02-27858594


Web: http://www.ibms.sinica.edu.tw/pi_webpage/blue_style2016/index.php?

p_id=38&journal_info_sysid=105608

Education

1986-1990 B.S., Medical Technology, National Yang-Ming Medical University, Taiwan

1992-1998 Ph.D., in Biochemistry and Molecular Biology, University of Texas

Southwestern Medical Center at Dallas, USA


1990-1992 Research Assistant, Academia Sinica, Taipei, Taiwan

1998 Postdoctoral Research Fellow, Dept. Biochemistry, Texas Southwestern

Medical Center at Dallas, USA

1999-2005 Postdoctoral Research Fellow, Program of Molecular Medicine, U. of

Massachusetts Medical School, USA

2005-2006 Scientist, Product of Development, CellPoint Diagnostics, Inc. USA

2006-2012 Assistant Research Fellow, Institute of Biomedical Sciences, Academia Sinica,

Taiwan

2013-present Associate Research Fellow, Institute of Biomedical Sciences, Academia Sinica,

Taiwan

Research Interests

In the central nervous system, each neuron receives thousands of synaptic connections from

others and modifies the strength of individual synapses independently with varying degrees of

stability. This experience-dependent synaptic plasticity underlies the molecular and cellular basis

of learning and memory. Accumulating evidence has suggested that regulated translation of

localized mRNAs at specific synapses is one of mechanisms that modify long-term plasticity and

memory. Several RNA-binding proteins have been implicated in targeting specific mRNAs to

dendrites and/ or regulating translation in response to synaptic activity. Among them is CPEB

(cytoplasmic polyadenylation element binding protein), which promotes dendritic transport and

polyadenylation-induced translation of CPE-containing (UUUUAU or similar) mRNAs. The

study of how CPEB functions in neurons suggests a plausible model whereby transport and

translation of specific mRNAs can be regulated by their cognate RNA-binding proteins with

spatial and temporal precision to influence plasticity at the stimulated synapse, thereby stably

modifying only that connection. Thus, the study of RNA-binding proteins in synaptic

translational control will help identifying proteins (i.e. molecular molecules of memory)

involved in plasticity, learning and memory. The current focus in the lab is to characterize other

CPEB family members, CPEBs2-4, in the mammalian neurons. While we continues the research

40

on translational control in synaptic plasticity and memory, we also study such a regulation in other

physiological functions like olfaction, respiration and thermogenesis.


1989 Book Prize, National Yang-Ming Medical University, Taiwan

1997 Robert A. Welch Predoctoral Fellowship, USA

1998 Robert A. Welch Postdoctoral Fellowship, USA

2001-2003 Charles King Trust Postdoctoral Fellowship from the Medical Foundation, USA

41

Bertrand Chin-Ming Tan, Ph.D.

Department of Biomedical Sciences, College of Medicine

Chang Gung University

No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33302, Taiwan

Phone No.: 03-2118800 ext.5067

Fax No.: 03-2118700


Web: http://ls.cgu.edu.tw/files/11-1038-1558.php

Education

1991-1995 B.A., Molecular & Cell Biology, Univ. of California, Berkeley

1998-2003 Ph.D., Institute of Molecular Medicine, National Taiwan University, Taiwan


2004-2007 Postdoctoral Research Fellow, Institute of Molecular Medicine, National

Taiwan University

2007 -2011 Assistant Professor, Department of Biomedical Sciences/Graduate Institute of

Biomedical Sciences, College of Medicine, Chang Gung University

2011-2015 Associate Professor, Department of Biomedical Sciences/Graduate Institute of

Biomedical Sciences, College of Medicine, Chang Gung University

2015-present Professor, Department of Biomedical Sciences/Graduate Institute of Biomedical

Sciences, College of Medicine, Chang Gung University

Research Interests

Post-transcriptional gene regulation in development and tumorigenesis


2013 Chang Gung University Research Excellence Award

2015 Chang Gung University Research Excellence Award

2015 Academia Sinica Research Award for Young Research Investigators

2015 MOST Wu Ta-You Research Award

42

Tse-Hua Tan, Ph.D.

Immunology Research Center, National Health Research Institutes

35, Keyan Road , Zhunan Town, Miaoli, Taiwan

Phone No.: 037-246166 ext. 37601

Fax No.: 037-586642



Education

1980 B.S. in Chemistry, National Taiwan University, Taipei, Taiwan

1987 Ph.D. in Molecular Biology (Arnold J. Levine’s Lab), Princeton University,

Princeton, New Jersey, USA


1987-1989 Postdoctoral Fellow (Robert G. Roeder’s Lab), The Rockefeller University,

New York, New York, USA

1989-1992 Principal Investigator, Laboratory of Experimental Immunology, National

Cancer Institute-Frederick Cancer Research & Development Center, Frederick,

Maryland, USA

1992-1997 Assistant Professor, Department of Microbiology & Immunology, Baylor

College of Medicine, Houston, Texas, USA

1997-2000 Associate Professor (tenured), Department of Microbiology & Immunology,

Baylor College of Medicine, Houston, Texas, USA

2003-2012 Director, NIH Training Program in Immunology, Baylor College of Medicine,

Houston, Texas, USA

2014-2015 Chair Professor (joint appointment), Graduate Institute of Immunology, China

Medical University, Taiwan

2014-2015 Honorary Director (joint appointment), Research and Development Center for

Immunology, China Medical University, Taiwan

2000-present Professor (tenured), Department of Immunology (renamed as Dept. of

Pathology & Immunology since 2009), Baylor College of Medicine, Houston,

Texas, USA

2013-present Professor (joint appointment), Institute of Biotechnology, National Tsing-Hua

University, Taiwan

2014-present Professor (joint appointment), Department of Biological Science and

Technology, National Chiao Tung University, Taiwan

2007-present Distinguished Investigator and Founding Director, Immunology Research

Center; Director, Transgenic Mouse Core (since 2010), National Health


43

Research Interests

Protein Kinases and Phosphatases in T-cell Signaling, Autoimmunity, and

Inflammation-induced Diseases

Tse-Hua Tan has made significant contributions to the research fields of cancer research, signal

transduction, and T cell-mediated diseases. He made a seminal discovery that mutations of the

tumor suppressor gene p53 lead to the activation of its oncogenic activity. In particular, Dr.

Tan’s group is among the first to demonstrate the critical role of JNK in apoptosis. His highly

cited paper in 1996 is the first report indicates that sustained activation of JNK is responsible

for apoptosis. Dr. Tan’s team has cloned and characterized multiple novel signaling molecules

particularly MAP4K family kinases (HPK1/MAP4K1, GLK/MAP4K3, HGK/MAP4K4) and

protein phosphatases (JKAP/DUSP22, DUSP14, PP4) that regulate the JNK-MAPK cascade.

Dr. Tan’s current research focuses on studying the roles of MAP4K family kinases and DUSP

family phosphatases in T-cell signaling and inflammation-induced human diseases, particularly

autoimmune diseases, cancer, and type 2 diabetes. He has published 110 papers with over 8,400

citations. H index: 47.


1982-1987 Prize Fellowship, Princeton University, USA

1988-1990 Postdoctoral Fellowship, Cancer Research Institute, USA

1996 Junior Faculty Research Award, American Cancer Society, USA (declined)

1996-2001 Scholar Award, The Leukemia and Lymphoma Society (formerly Leukemin

Society of America), USA

1997-1998 President, Society of Chinese Bioscientists in America (SCBA)-Texas

Chapter, USA

2001-2002 Regular Member, Pathology C (PTHC) Study Section, NIH, USA

2002-2006 Charter Member, Cancer Molecular Pathobiology (CAMP) Study Section,

NIH, USA

2009- present Editor, Journal of Signal Transduction, USA

2009- present Editor, American Journal of Translational Research, USA

2010-2013 Councilor, Society of Chinese Bioscientists in America (SCBA)

2011- present Editor, Journal of Cell & Bioscience, USA

2013 The 22th Wang Min-Ning Memorial Award for Outstanding Contribution to

the Medical Science and Technology Development, National Health, and

Society, Taiwan (第 22屆王民寧獎之「學術研究成果對醫藥科技發展、國

民健康和國家社會傑出貢獻獎」)

2014-present TBF Chair in Biotechnology, Taiwan Bio-Development Foundation (TBF) ,

Taiwan (台灣生技醫藥發展基金會學術講座-第一屆「TBF 生技講座」)

2016- present Associate Editor, Journal of Biomedical Science, Taiwan

44

Lung-Chi Chen, Ph.D.

Department of Environmental Medicine

New York University School of Medicine

57 Old Forge Rd., Tuxedo, NY 10987, USA

Phone No.: 845/731-3560


Web: http://www.med.nyu.edu/biosketch/lcc4

Education

1972-1976 B.S. Public Health, National Taiwan University, Taiwan

1976-1978 M.S. Environmental Health, New York University, N.Y. N.Y. USA

1978-1983 Ph. D. Environmental Health, New York University, N.Y. N.Y. USA


1982-1985 Assistant Professor, Environmental Studies Institute, Drexel University,

Philadelphia, Pennsylvania

1985-1988 Research Scientist, Department of Applied Biological Science and Energy

Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts

1989-1994 Research Assistant Professor, Department of Environmental Medicine, NYU

School of Medicine, Tuxedo, New York

1994-1999 Assistant Professor, Department of Environmental Medicine, NYU School of

Medicine, Tuxedo, New York

1999-2007 Associate Professor with tenure, Department of Environmental Medicine, NYU

School of Medicine, Tuxedo, New York

2007-present Professor with tenure, Department of Environmental Medicine, NYU School of

Medicine, Tuxedo, New York

Research Interests

1. Nanoparticle Toxicity and functional utilization.

2. Impact of climate change on cardiopulmonary health

3. Health effects of tobacco products and electronic cigarette

4. The role of health disparity in air pollution-induced cardiopulmonary diseases

5. Gene-environment interactions in environmentally induced diseases

6. Effects of particulate air pollution in the pathogenesis of atherosclerosis

7. Mechanisms of air pollution induced asthma

8. Pollutant-induced alterations in biological response modifiers and associated membrane

receptors

9. Signal transduction pathways associated with oxidative stress

10. Fetal origins of adult diseases


2016 Career Achievement Award, Respiratory and Inhalation Specialty Section,

Society of Toxicology

45

2005 Paper of the Year Award, Respiratory and Inhalation Specialty Section, Society

of Toxicology. Sun Q, Wang A, Jin X, Natanzon A, Duquaine D, Brook RD,

Aguinaldo JG, Fayad ZA, Fuster V, Lippmann M, Chen LC, Rajagopalan S.

Long-term air pollution exposure and acceleration of atherosclerosis and

vascular inflammation in an animal model. JAMA. 2005 Dec

21;294(23):3003-10. PMID: 16414948

2000 Paper of the Year Award, J Occup Environ Med. Fine JM, Gordon T, Chen LC,

Kinney P, Falcone G, Sparer J, Beckett WS. Characterization of clinical

tolerance to inhaled zinc oxide in naive subjects and sheet metal workers. J

Occup Environ Med. 2000 Nov;42(11):1085-91. PMID: 11094787

46

Angela Yu-Chen Lin, Ph.D.

Graduate Institute of Environmental Engineering, College of Engineering


No. 71, Chou-Shan Rd., Taipei 106, Taiwan

Phone No.: 02-33664386

Fax No.: 02-33669828


Web: http://laboec.blogspot.tw/

Education

1999 B.S., Environmental Science and Engineering, California Institute of

Technology (Caltech), USA

2000 M.S., Civil and Environmental Engineering, Stanford University, USA

2005 Ph.D., Civil and Environmental Engineering, Stanford University, USA


2005-2006 Engineer, Kennedy/Jenks Consultants

2006-2010

2010-2014

2014-2015

2016 Jan-Jul

2014-present

Assistant Professor, Graduate Institute of Environmental Engineering, National

Taiwan University (NTU)

Associate Professor, Graduate Institute of Environmental Engineering, National

Taiwan University (NTU)

UPS Visiting Associate Professor at Civil and Environmental Engineering,

Stanford University

Visiting Professor in the Research Institute for Sustainable Urban Development,

Hong Kong Polytechnic University, Hong Kong

Professor, Graduate Institute of Environmental Engineering, National Taiwan

University (NTU)

Research Interests

1. Trace analysis of organic contaminants in environmental matrix

2. Occurrence, fate and transport of emerging contaminants (i.e. pharmaceuticals and personal

care products (PPCPs), endocrine-disrupting compounds (EDCs), perfluorinated chemicals

(PFCs)) in the aqueous environments

3. Natural attenuation

4. Natural photodegradation and free chlorine sunlight photolysis of pharmaceuticals in the

aqueous environment

5. Water reuse

6. Engineering treatment of emerging contaminants


1996-1999 Caltech Upper-Class Merit Full Scholarship Award-Carnation Foundation

1999 Tau Beta Pi Engineering Honor Society

1999-2002 U.S. National Science Foundation (NSF) Graduate Research Fellowship Award

47

2013

2013

Ta-You Wu Memorial Award for Young Scholars, Minister of Science and

Technology (MOST), Taiwan

Academic-Industry Research Project Award, Minister of Science and

Technology (MOST), Taiwan

2014

2014-2015

Winner of Elsevier Scopus Young Researcher Award in Environmental Science

Field

UPS Visiting Professorship with Funding at Stanford University

48

Shao-Yu Tsai, Ph.D., RN

School of Nursing, College of Medicine, National Taiwan University


Phone No.: 02-23123456 ext.88904

Fax No.: 02-23219913


Web: http://nursing.mc.ntu.edu.tw/en/news/Faculty/Pages/Tsai%2c-Shao-Yu.aspx

Education

1995-1999 BSN, Nursing, National Taiwan University, Taiwan

2001-2003 MSN, Nursing, University of Washington, USA

2003-2008 Ph.D., Nursing, University of Washington, USA


1999-2001 Staff nurse, infant intensive care unit, National Taiwan University Hospital

2002-2003 Teaching Assistant, School of Nursing, University of Washington

2003-2008 Research Assistant, Sleep Laboratory, School of Nursing, University of Washington

2009-2010 Lecturer, School of Nursing, National Taiwan University

2010-2014 Assistant Professor, School of Nursing, National Taiwan University

2014-present Associate Professor, School of Nursing, National Taiwan University

2014-present Adjunct Supervisor, Department of Nursing, National Taiwan University Hospital

Research Interests

Pediatric nursing, Sleep in women and children


1996 National Taiwan University Presidential Award

1997, 1998 Kuo-Chang Lin Memorial Nursing Scholarship

1999 Honor of Taiwan Nurses Association for Academic Excellence

2003 Graduate School Top Scholar Award for the 2003-2004 Academic Year, Vigfusson

Graduate Fellowship, University of Washington

2004 1st Place Poster Winner, 37th Annual Communicating Nursing Research Conference,

April 22-24, Portland, Oregon.

2005 Hester McLaws Nursing Scholarship, University of Washington

2006 Virginia Henderson Research Grant Award, Sigma Theta Tau International

2006 Psi Chapter-at-Large Research Grant Award, Sigma Theta Tau International

2008 University of Washington School of Nursing Outstanding Dissertation Award

2011, 2012,

2013

臺灣大學學術研究績效獎勵

2013 臺灣大學醫學院第二屆李鎮源院長紀念醫學獎

2013 Best Young Investigator Presentation, 7th Bi-Annual Conference on Pediatric Sleep

Medicine in Amelia Island, Florida, USA

2014 Invited Speaker, Rhythms of Infant Life conference, Durham University, UK

49

Shu-Li (Julie) Wang, Ph.D.

National Institute of Environmental Health Sciences

National Health Research Institutes

Phone No.: 037-246-166 ext. 36509

Fax No.: 037-587406



Education

1986-1990 B.S, Public Health, National Taiwan University, Taiwan

1990-1995 Ph.D., Epidemiology and Public Health, University of London, UK


1995-1996 Post-doctoral researcher, Department of Gerontology, University of Cambridge,

U.K

1996-1997 Post-doctoral researcher, Division of Epidemiology & Public Health, Institutes

of Biomedical Sciences, Academia Sinica, Taiwan

1997-2000 Assistant / Associate Professor, Department of Public Health, Chung-Shan


2000-2004 Assistant Principal Investigator, Division of Environmental Health and

Occupational Medicine, National Health Research Institutes, Taiwan

2001-2002 Adjunct Assistant Professor, Graduate Institute of Public Health, National

Cheng Kung University, Taiwan

2004-2008 Associate Principal Investigator, Division of Environmental Health and

Occupational Medicine, National Health Research Institutes, Taiwan Associate

Professor, Graduate Institute of Occupational Safety and Health, Kaohsiung


2009-present Full Investigator, Division of Environmental Health and Occupational

Medicine, National Health Research Institutes, Taiwan

2010-present

2012-2013

Professor, Department of Public Health, China Medical University, Taiwan

Visiting Scholar, National Institute of Environmental Health Sciences, National

Institute of Health (NIEHS/NIH), U.S.A.

2013-present

2015-present

Adjunct Professor, Department of Public Health, National Defense Medical

Center, Taiwan

Adjunct Professor, Center for Environmental Medicine, Kaohsiung Medical

University, Taiwan

Research Interests

Wang’s research interests are mainly on Environmental Children Health with regards to

pollutant form air, water, food, climate change, and life styles, and its effects on endocrine

system, neuron-cognitive function, immunity (i.e. obesity, behavioral problem, allergic diseases).

The approach is primarily from pre-birth cohort, which is the follow-up of children from in utero

till adolescents. The studied causation agents include endocrine disruptors (i.e. phthalates,

dioxins), metals (lead, arsenic, cadmium), and pathogen (virus).

50

Professor Wang is also interested in searching for environmental factors contributing to the

pathogenesis of cardiovascular disease and cancer. The interaction between the environment and

genes is investigated to understand how the environment may affect gene expression, and how

genetic factors might modify the effect of pollutants.

The research interests might also include environmental and occupational health with

regards to electroplating industry, semi-conductor, and epidemiological investigations for

residents living with high background exposure level to toxic metals (Changhua) and dioxins (i.e.

An-Nan area). It is hoped that the research may help managing the environmental pollutions,

preventing the related health effects, and improve heath and welfare particularly among maternal

and children population.


1995 Travel Award, International Diabetes Federation (IDF)

1996 Travel Award, International Diabetes Federation (IDF)

1997 Academia Sinica Travel Award

1998 Academia Sinica Travel Award

1999 Special Research Award, National Science Council (NSC)

2002 Young Scientist Award, Asian Conference on Occupational Health (ACOH)

2008

2010

Award for Junior Research Investigators, National Health Research Institutes

Research (NHRI)

Who’s Who in Medicine and Healthcare Board U.K.

72

Edward T. H. Yeh, M.D.

Department of Cardiology, The University of Texas M.D. Anderson Cancer

Center, 1515 Holcombe Blvd. Houston, U.S.A.

Phone No.: +1-713-792-1960

Fax No.: +1-713-745-1942


Web: http://www.sentrin.org

Education

1976 B.S., University of California, Berkeley, U.S.A.

1980 M.D., University of California, Davis, U.S.A.


1980-1982 Intern and Resident, Children's Hospital of San Francisco, U.S.A.

1982-1983 Resident, Boston Veteran Administration Hospital, U.S.A.

1983-1986 Research Fellow, Immunology, Harvard Medical School, U.S.A.

1986-1987 Clinical Fellow, Rheumatology, Massachusetts General Hospital, U.S.A.

1987-1992 Assistant Professor, Harvard Medical School, U.S.A.

1992-1995 Clinical Fellow, Cardiology, Health Science Center at Houston, University of

Texas, U.S.A.

1992-1998 Associate Professor, Health Science Center at Houston, University of Texas,

U.S.A.

1998-2000 Professor, Health Science Center at Houston, University of Texas, U.S.A.

2000-present Professor and Chairman, Department of Cardiology, M.D. Anderson Cancer

Center, University of Texas, U.S.A.

Research Interests

1. Ubiquitin-like proteins (SUMO and NEDD8)

2. Stem cell for cardiac repair

3. Cardiac complications of anti-cancer therapy

4. Inflammation and coronary artery disease


2008 McNair Scholar, Texas Heart Institute

2006 Academician, Academia Sinica

2001 Distinguished Alumnus Award, U. C. Davis Medical School

2000 Association of American Physicians

1993 American Society of Clinical Investigation

1992-1999 Established Investigator Award, American Heart Association

1987-1990 Upjohn/Massachusetts General Hospital Scholar Award

1987-1990 Investigator Award, Arthritis Foundation

1973 Kraft Prize for Undergraduates at U.C. Berkeley

2016 biomedical research symposium of national health...

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