SPONSORED BY:• American Physiological Society

• American College of Sports Medicine

• Canadian Society for Exercise Physiology

Westin Westminster HotelWestminster, ColoradoOctober 10-13, 2012

2012 APS Intersociety Meeting

The Integrative Biology of Exercise VI

Call for Abstracts

http://bit.ly/ExerciseConference

Abstract Deadline: June 20, 2012

This is the sixth meeting in the series of exercise physiology that began in 1992. This popular meeting includes intersociety collaborations from the American Physiological Society (APS), the American College of Sports Medicine (ACSM), and the Canadian Society for Exercise Physiology (CSEP). This meeting is designed to bring together scientists from all over the world who have research interest in the broad area of exercise physiology. The meeting is designed to provide a strong scientific program with participant interaction and emphasize emerging research performed by young investigators. The participants will likely focus on recent important advances in the traditional areas of interest in exercise (e.g. metabolic control, cell signaling, satellite/stem cells biology, hypertrophy, vascular adaptations) as well as significant new developments in emerging areas of science that have great relevance to investigators interested in exercise (e.g. mechanical signal transduction, AMPK, cytokines). The goal is to provide an in-depth understanding of exercise physiology and interdisciplinary efforts to assess its impact on the systems of the body. In addition, the goal is to outline directions for future work and to interest new investigators and students in pursuing research opportunities to understand the integrative biology of exercise and its relation to gender and aging. The dedicated scientists who put together the exciting scientific program are as follows: P. Darrell Neufer, PhD (Chair) East Carolina University Keith Baar, PhD University of California, Davis Frank Booth, PhD University of Missouri David Brown, PhD East Carolina University Paige Geiger, PhD Kansas University Medical Center

Mark Hargreaves, PhD University of Melbourne, Australia Judy Muller Delp, PhD University of Florida Michael Joyner, MD The Mayo Clinic William Kraus, MD Duke University

Deborah Muoio, PhD Duke University Henriette Pilegaard, PhD August Krogh Institute, Denmark Scott Trappe, PhD Ball State University Espen Spangenburg, PhD University of Maryland

Abstract-based Travel Awards for Postdoctoral and Graduate Students To encourage the participation of young scientists in training, awards will be granted to postdoctoral fellows and graduate students for best abstract presentation. The awards will consist of a cash prize and certificate.

To be considered for an award the candidate must: Submit an abstract for the meeting. Be the first author on the abstract. Must be a student or postdoctoral fellow.* Indicate on the “Details” page of the abstract site, their desire to be considered for the award. Complete and submit the online award application form by the deadline.

To apply for the abstract-award application form, please visit: https://www.the-aps.org/awardapps. The deadline for submitting the abstract-based award application is June 27, 2012. Please note that we are only accepting applications for this award online. Incomplete applications will not be accepted.

Award applicants will be judged prior to the meeting and the winners announced during the closing meeting banquet and awards ceremony.

For more information on the Abstract-based Travel Awards, please contact the APS Meetings Department at: meetings@the-aps.org

*Postdoctoral Fellows must have received their degree within the last five years of the meeting dates.

1

About the Meeting

The Organizing Committee Members

Awards

Registration Opens at 3:00 PM on Wednesday, October 10, 2012 Opening Reception at 6:00 PM

Thursday October 11, 2012

Friday October 12, 2012

Saturday October 13, 2012

8:30 AM-10:45 AM Concurrent Symposia

11:00 AM-12:00 Noon Plenary Lecture/Discussion

Personalized Medicine Track Integrating Human “Omics” to the Molecular Physiology of Exercise Chair: William Kraus Exercise Adaptations Track Mechanisms Behind Adaptations to Physical Activity/Inactivity Chair: Henriette Pilegaard

Cardiovascular Track Cardiovascular Benefits of Exercise: Insight from Animal Studies Chair: David Brown

Lipid Metabolism Track Fit, Fat and Lean Liver: Exercise Adaptations in Non-traditional Tissues Chair: Espen Spangenburg Adaptations of the Heart: Traditional and Non-traditional Research Speaker: Leslie Leinwand

Physical Activity is Necessary for Optimal Brain Function Chair: Michael Joyner The Impact of Heat Shock Protein Expression on Muscle Metabolism, Exercise Capacity and Disease Prevention Chair: Paige Geiger Town Hall Meeting Led by: Jim Whitehead Martin Frank

Afternoon Activities

12:00 Noon-1:15 PM Lunch 1:15 PM-3:15 PM Poster Presentations and Exhibits

12:30 PM-1:15 PM Lunch

12:30 PM-1:15 PM Free Time 1:15 PM-3:15 PM Poster Presentations and Exhibits

3:15 PM-5:30 PM Concurrent Symposia

Personalized Medicine Track Personalized Exercise Prescription Based Upon Integrative Biology Chair: Frank Booth Exercise Adaptations Track Acetylation: Linking Changes in NAD to Metabolism and Growth Chair: Keith Baar

Cardiovascular Track Cardiovascular Benefits of Exercise: Insight from Human Studies* Chair: Judy Muller Delp Lipid Metabolism Track Skeletal Muscle Lipid Droplet Biology in Exercise and Disease* Chair: Deborah Muoio

Hot Topics in Exercise Physiology Chair: P. Darrell Neufer Unified Cellular and Molecular Mechanism of Muscle Hypertrophy Chair: Keith Baar

Evening Events

5:30 PM -7:00 PM Poster Presentations Evening Free Explore the urban city of Westminster or visit the nearby vibrant city of Boulder.

3:30 PM-6:00 PM Recreational Activities Challenge your colleagues to a friendly game of bowling, soccer, or even ice skating at nearby locations. 6:00 PM-7:00 PM Dinner 7:00 PM-9:30 PM Poster Presentations

7:00 PM-10:00 PM Banquet and Awards Presentation: Awards, Dinner Lecture and Music. (Included with registration).

*Friday Afternoon Concurrent Sessions begins at 1:15 PM-3:30 PM

Abstract Deadline The deadline for the submission of abstracts is June 20, 2012 at 11:59 PM EST.

Abstract Fee All abstracts must be submitted electronically and require an abstract handling payment of $75. The abstract handling fee is non-refundable and must be submitted at the time of abstract submission. Payment may be made with a Visa, MasterCard, or American Express credit card. A receipt of the abstract handling charge will be emailed to the first author only. The abstract fee does not include your registration for the meeting.

Abstract Submission Important Information Abstracts should contain a sentence stating the study objective (unless given in the title); a brief statement of methods, if pertinent; a summary of the results obtained; and a statement of the conclusions. Use a short, specific title. Capitalize initial letters of trade names and use standard abbreviations for units of measure. Non-standard abbreviations should be spelled-out in full at first mention, followed by the abbreviation in parentheses.

All investigations involving humans and animals reported in abstracts must have been conducted in conformance with guidelines for experimental procedures as set forth in the Declaration of Helsinki and the APS “Guiding Principles for the Care and Use of Animals.” The Organizing Committee will refuse abstracts in which evidence of adherence to these guidelines is not apparent.

2

Abstracts

Week-At-Glance

All abstracts submitted for this meeting will be bound with the official program and handed out onsite. These abstracts are considered in press of The Physiologist. They will appear in the December 2012 issue and should be cited as “program number [#], in press” directly reproduced from the electronic submission. Authorization of the senior author certifies that the research adheres to the APS “Guiding Principles for the Care and Use of Animals”. Visit http://bit.ly/APSGuidingPrinciples to view the APS Guiding Principles.

Software Required Submission requires the use of the Internet and Adobe Acrobat Reader. To download the latest version of: Microsoft Internet Explorer (the preferred browser for this site), please visit http://windows.microsoft.com/en-US/internet-explorer/products/ie/home. To download a copy of Adobe Acrobat Reader, please visit http://get.adobe.com/reader/.

Time Commitment The submission process will take approximately 15-20 minutes depending on the speed of your Internet connection. The deadline for submitting abstracts is June 20, 2012. Please note that those waiting until the deadline to submit will experience significant delays due to the high volume of traffic on the submission site! For best results, do not wait until the deadline to submit your abstract…..the site is open now! Abstract Categories You will need to choose one of the following abstract categories in the “Details” section as part of your abstract submission. If you don’t see a relevant topic category for your abstract, please choose the topic that is nearest to the relevance of your research. The Organizing Committee will review each abstract to determine its proper placement in the programming of the poster sessions.

Aging Blood Flow Regulation Cardiovascular CHO/ Lipid Metabolism Comparative Physiology Contractile Proteins and Muscle Design Cytokines Endocrine Exercise and Drug Interaction

Extracellular Matrix and Connective Tissue Fatigue Gender Differences Genomics/ Proteomics Inflammation Integrated Exercise Response Microcirculation Molecular Regulatory Mechanisms Muscle Function and Adaptation

Muscle Injury Neural Control Other Oxidant/Antioxidant Effects Oxygen Transport Physical Inactivity and Chronic Disease Regeneration Signalling Stem Cells

Abstract Revisions Do not submit the same abstract more than once. The abstract submission site allows for revisions. Go to the login (Returning User) page and enter your login name and the password that you provided in your original submission to start the revision process. Do not submit revisions under “New User” or you will be charged for a new abstract. The deadline for revisions is the same date as the abstract deadline: June 20, 2012, 11:59 PM EST.

Withdrawal of Abstracts To withdraw your abstract, login as a “Returning User” and enter in your login name and the password that you provided in your original submission. You will see a screen that shows you existing abstracts. Click on the “Delete” next to the abstract ID you would like to withdraw. The next screen will show the deleted abstract status as “withdrawn by author.” Print a copy of this screen for your records. Withdrawals must be completed online by June 20, 2012, 11:59 PM EST. Withdrawn abstracts are not refundable.

Abstract Acceptance and Presentation of Papers All abstracts that are successfully submitted for the meeting will be accepted for a poster presentation during this meeting. It is a very rare occasion that an abstract is not accepted by the Organizing Committee. First author abstract presenters will be notified of the exact date, time, location, and poster board number in July. The first author must present the paper unless alternate arrangements are made with the APS Meetings Department. No paper may be read by title. Please note that electrical outlets are not available in the poster session area. Please do not wait until your acceptance email to make your housing and travel reservations, and registering for the meeting.

Abstract Questions? If you have questions about this meeting or require some assistance, please contact the APS Meetings Department at: voice: 1-301-634-7967; fax: 1-301-634-7264; email: meetings@the-aps.org. Registration and Fees The registration fee includes entry into all scientific sessions, opening reception and poster sessions. Register early! The fees listed below do not include housing or abstract submissions. Housing and abstract submissions are separate charges. The advance registration deadline is Wednesday, September 5, 2012.

Type Advance Onsite APS Member* $500 $600 ACSM/CSEP Member* $500 $600 Retired APS Member* $300 $400 Nonmember $600 $700 Postdoctoral $350 $450 Student $300 $400

*Member refers to a member in good standing of the American Physiological Society, American College of Sports Medicine, or Canadian Society for Exercise Physiology. You must supply proof of membership when registering.

3

Registration

Advance Registration To register, please choose from one of the three registration methods below. Once your registration has been received by the APS office, it will be processed and entered into the registration system.

Badges and receipts will be mailed to advance domestic registrants before the meeting. If you did not receive or if you have lost your meeting badge prior to the meeting, please come to the registration desk for a replacement. Foreign registrants may pick up their meeting badge, receipt, and other meeting materials at the registration desk. For more information please visit http://bit.ly/AdvanceRegistration.

Registration and Payment Options You may register for the meeting in one of the following ways:

Online: To register for this meeting visit http://bit.ly/ExerciseRegisterOnline. Your registration receipt will be automatically emailed to you after the submission has been completed.

Mail/Fax: Please print out the registration form and complete the information. Mail or fax the form to the APS office along with your credit card information or a check. Visit http://bit.ly/RegisterMail to download the registration form for this meeting.

The American Physiological Society accepts the following major credit cards: Visa, MasterCard, and American Express for registration payment. The American Physiological Society also accepts both personal and institute checks. All checks must be made out in US Dollars, drawn from a US bank and made payable to The American Physiological Society. Please make sure that the check accompanies a completed registration form to avoid processing delays. Please note that the American Physiological Society does not accept purchase orders for registration payments. Please use a credit card or check.

APS Member Registration Any person who is a regular member of the American Physiological Society and whose membership dues are current through the end of the year in which the meeting is being held. Those registering as an APS member and whose dues have lapsed may either renew their membership dues before registering or register as a nonmember.

ACSM/CSEP Member Registration Any person who is a regular member of the American College of Sports Medicine or the Canadian Society for Exercise Physiology and whose membership dues are current through the end of the year in which the meeting is being held.

Retired APS Member Registration Any person who is an emeritus member of the American Physiological Society and whose membership dues are current through the end of the year in which the meeting is being held.

Nonmember Registration Any person who is not a member of the American Physiological Society or a member whose membership dues have lapsed.

Postdoctoral Registration Any person who has received a Ph.D. degree in physiology or related field, within four years of this meeting, as attested to by the department head is eligible to register at the postdoctoral fee. A statement signed by the department head must accompany the registration form and remittance when registering. If you have received your Ph.D. after the four years, please register as a member or nonmember. If you would prefer to email your letter certifying your postdoctoral status please send to meetings@the-aps.org or you may simply fax it to: 1-301-634-7264.

Student Registration Any student member or regularly matriculated student working toward a degree in one of the biomedical sciences is eligible to register at the student fee. Nonmember postdoctoral fellows, hospital residents and interns, and laboratory technicians do not qualify as students. For nonmember students, certification of eligibility signed by the department head or research advisor must accompany the remittance for advance student registration. Member students need only supply the APS membership ID number.

Special Assistance Please contact the APS in order for us to make any special arrangements for attendees who require special assistance because of a disability or a diet request. This meeting and the meeting location is accessible to all participants. To contact the APS regarding special assistance, please email: meetings@the-aps.org.

Registration Cancellation Policy Please visit http://bit.ly/CancellationPolicy to review the cancellation policy and instructions on how to cancel your meeting registration.

Program/Abstract Volume All abstracts submitted for this meeting will be bound with the official program and handed out onsite. These abstracts are considered in press of The Physiologist. They will appear in the December 2012 issue and should be cited as "program number [#], in press". All registrants should come to the onsite Registration Desk to receive a copy of the program. You must show your registration badge to obtain a program.

Continuing Medical Education (CME) Continuing Medical Education credits will not be available for this meeting.

Invitation Letters and Visa Processing for Foreign Attendees Please email meetings@the-aps.org to contact the American Physiological Society Meetings Department if you would like to have an invitation letter

4

sent to you for this meeting. Please note that APS will only send invitation letters to the person requesting the letter. All person’s requesting an invitation letter must be registered for the meeting. The invitation letter does not constitute any financial assistance for the meeting. For information on seeking a visa to travel to the United States for this meeting, visit http://bit.ly/VisaInfo.

Target Audience The intended audience for this meeting includes established scientists, young investigators, and students involved in teaching, research and clinical fields related to exercise biology.

Registration Questions? If you have questions about this meeting or require some assistance, please contact the APS Meetings Department at: voice: 1-301-634-7967; fax: 1-301-634-7264; email: meetings@the-aps.org.

Meeting Location The 2012 APS Intersociety Meeting: The Integrative Biology of Exercise VI will be held at the Westin Westminster Hotel. The address for the meeting location is: Westin Westminster, 10600 Westminster Blvd., Westminster, CO 80020, Tel: 1-303-410-5000. Please visit http://www.westindenverboulder.com to view the hotel website.

Housing Reservations Housing has been reserved at the Westin Westminster Hotel. Hotel rooms have been reserved for APS attendees at a special meeting rate of $159 for a single or double room. To make a reservation via telephone: Call the property directly at: 1-800-WESTIN1 (within the US) or 1-303-410-5000 (outside the US) and ask for reservations. Be sure to identify yourself as an APS Meeting Attendee and provide the meeting dates and provide the group rate of $159. Or make your reservation online with a few quick and easy steps. To make a reservation online: Visit http://bit.ly/WestinReservations to make your reservation online. Select the arrival date and the number of nights. Review the room requests.

The property will require a valid major credit card when making your reservation. The property will provide you with a confirmation number and all cancellation and early departure policies and penalties. Please note that there is no charge for a change or cancellation if it is received at least 24 hours prior to arrival and a cancellation number is received. Cancellations received within 24 hours of arrival will be subject to a charge of 1 night’s room plus tax.

The deadline for making housing reservations is September 18, 2012. Please make your reservation early.

Housing Amenities Each guest room is equipped with coffee maker, data ports, complementary Internet service, voicemail, hairdryer, ironing facilities, cable television, in-room movies, refrigerator, and adjustable thermostats. All guest rooms in the hotel are 100% smoke free. For more information on the in-room amenities please visit http://bit.ly/WestinAmenities.

The hotel features three restaurants that are sure to delight your dining palate. O’s restaurant provides the diner with a delicious array of steaks and seafood fare in a casual dining experience. Attached to the restaurant is the O Room where guests can unwind over a drink and catch-up with colleagues. In addition, a short walk from the hotel, the Westminster Promenade offers alternative restaurants that are sure to please every palate.

There is also a small business center, laundry and dry-cleaning service, gift shop, health center, a heated outdoor pool, outdoor whirlpool, nearby hiking, jogging, and biking paths, spa, a local golf course, Internet service, local and toll free call access, and free shuttle service to nearby locations. Complimentary self-parking facilities are also available. For more information on the amenities that the Westin Westminster has to offer, please visit http://bit.ly/WestinReservations.

Local Information The Westin Westminster Hotel is located between Boulder and downtown Denver, Colorado. Its convenient location offers a one-of-a-kind opportunity to visit the natural wonders of Colorado. Visit the breathtaking slopes of the Rocky Mountains, Pikes Peak and the Garden of Gods. For an experience that will truly inspire curiosity and excite minds of all ages, discover a variety of exhibitions, programs, and activities at The Denver Museum of Nature and Science. These activities plus many shops and fine restaurants make the Westminster area the perfect blend of outdoor adventure and urban sophistication.

The Westin Westminster Hotel is easily accessible from the Denver International Airport being only a 20 minute ride away. Temperatures in this area during October usually range from the mid 40’s to upper 60’s making the outdoors ideal for all types of activities. For more information on the Westin Westminster Hotel, visit http://www.westindenverboulder.com. Transportation The Westin Westminster Hotel is located approximately 31 miles west of the Denver International Airport. The airport is served by most major and discount airlines, including Air Canada, AirTran, Alaska, America West, American Airlines, Big Sky, British Airways, Continental, Delta, Frontier, Great Lakes, JetBlue, Lufthansa, Mexicana, Midwest, Northwest, Southwest, Ted, United, and US Airways.

Taxi and Car Rental Taxi cab fares from Denver International Airport to the Westin Westminster Hotel are approximately $80 for a one-way trip. Please note: taxi cab

5

Housing and Travel

rentals are scarce in Westminster, so your return to the airport may need alternative arrangements or prior planning. There are car rental agencies located in the airport, including: Avis, Budget, Dollar, Enterprise, Hertz, National/Alamo and Thrifty.

SuperShuttle It is recommended that APS attendees make reservations for their transfer from the airport to the hotel and the return journey via SuperShuttle. The fare is approximately $25 one-way or $40 round trip. To make your reservation for a SuperShuttle transfer, please visit http://www.supershuttle.com/.

Arrival Information: Guests should proceed to the SuperShuttle ticket counter in the main terminal upon arrival at Denver International Airport, level 5 (same as baggage claim), check in and receive their tickets and will be directed to the van loading area. Shuttles depart for the Westin Westminster hourly.

Departure Information: Shuttles depart (by reservation only) from the Westin Westminster to Denver International Airport every hour on the hour. Attendees can call 800-BlueVan (800-258-3826) to make their return reservation at a time that best suits their flight departure time (we recommend being at the airport 1.5 hours prior to flight time). They will use their return ticket for the trip back to the airport.

Other Information To find out more information about ground transportation including driving directions, shuttle services, taxis and bus routes from Denver to the Westin Westminster Hotel, please visit http://www.denver.org/transportation/bus-train-taxi. There is also some helpful information about getting to the Westin Westminster hotel by visiting http://bit.ly/WestinHotel. The hotel address is: Westin Westminster, 10600 Westminster Boulevard, Westminster, Colorado, 80020. General Visa Information for Scientists Traveling to the United States As part of security procedures, applications for visas are being sent to the State Department in Washington, D.C., where they are reviewed. We advise scientists traveling to the United States to apply for a visa as early as possible (at least six months before visa is needed).

It is advised that you check with your local U.S. Consulate or embassy as soon as possible to find out what the earliest date is that you can apply for a visa and to schedule an appointment. Please see the web links section below. Because of the number of visas being processed and the need to be thorough with the reviews, this can take as long 8 weeks, especially for the countries that are listed on the State Sponsors of Terrorism List. If you are traveling from one of the countries on this list it is strongly advised that you begin your visa application process at least 6 months in advance of the meeting.

Some foreign attendees do not need to seek a visa to travel to the United States for a meeting. In order to qualify, the attendee must be a citizen of any of the countries on the Visa Waiver Program (VWP). For a list of the participating countries of the Visa Waiver Program, please see the web link below. All of the citizens who participate in the Visa Waiver Program are required to have a Machine-Readable Passport (MRP) in order to travel to the United States. If you do not have a MRP, you will have to apply for a visa.

Please note that all foreign visitors entering the United States will be fingerprinted and photographed upon arrival. Please visit the United States Department of State at http://www.usembassy.gov/ for further information on traveling to the United States

and to locate your nearest U.S. embassy. Please visit the Visa Waiver Program country listing at http://1.usa.gov/VisaWaiverProgram for further information on whether you qualify.

Preparing for your Visa Interview To help you prepare for your visa interview at your local U.S. Consulate or embassy, you will need to gather several documents which will help facilitate your visa application.

Apply for visa at least six (6) months in advance of the meeting. Provide your entire trip itinerary, including travel to any countries other than the United States, at the time of visa application. If completion of travel plans is contingent upon early approval of the visa application, specify this at the time of the application. Provide proof of scientific status. Provide evidence that you are intending to return to your country of residence. This includes such things as:

o Family ties in current country of residence o Property ownership o Bank account(s) o Employment contract or statement from employer showing that the position will continue after the dates of the meeting o School enrollment documentation

Provide meeting brochure (if available). Ask for a letter of invitation to attend the meeting. For security reasons, letters of invitation can only be sent to individuals who have

registered for the meeting. Email meetings@the-aps.org to contact the APS Meetings Department for more information and to request an invitation letter.

Please note that the American Physiological Society is not able to send letters of invitation directly to any U.S. Consulate or embassy via mail, fax, or email. The letter of invitation does not include your registration fee or any financial help for attending the meeting. Requirements vary by passport-issuing country and citizenship (not merely residency).

For the most current requirements and those specific to your situation, please visit http://www.usembassy.gov/ to check with your local U.S. Consulate or embassy or the U.S. Department of State Visa Services Information Web site.

6