2. takle gxalert - stop tb gxalert.pdf · 2014. 12. 22. · takle gxalert. gxalert. open-source...

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GxAlert Open-source data connectivity for the GeneXpert 6 th Annual WHO GLI Conference, Geneva Jeff Takle, Dir. of Innovation @Abt Associates May 2nd, 2014

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Page 1: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

GxAlertOpen-source data connectivity

for the GeneXpert

6th Annual WHO GLI Conference, Geneva

Jeff Takle, Dir. of Innovation @Abt Associates

May 2nd, 2014

Page 2: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

The Value of GxAlert

GxAlert rapidly moves test results from the lab back into the health system.

� Open source software + USB modem + Security software = 15min install

� Configurable alerts and dashboards (web-based, SMS text, and email)

� Focused on program-level and NTP-level management

� Our development roadmap is trying to answer 4 Big Questions (4BQ)

Page 3: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can GxAlert get patients

into appropriate

treatment faster?

Big Questions

Can we get

better quality

data, faster?

Does it lead to

NTP action?

Do results get

to patients?

Many more

steps in here…

Simple Questions

1

"GxAlert has revolutionized the TB

control program in Nigeria with faster

diagnostic results (with better

accuracy) in real time. It has further

made patients’ enrollment in

treatment centers much easier."

— Elom Emeka

Chief Medical Laboratory Scientist,

Nigerian Federal Ministry of Health

Page 4: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can we get

better quality

data, faster?

Does it lead to

NTP action?

Do results get

to patients?

Working on

“Clinician Referral”

“We saw 10x the

level of MDR we

expected!”

1Can GxAlert get patients

into appropriate

treatment faster?

Page 5: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can errors be

better managed?Can stockouts

be prevented?Can site selection

be optimized?

Build training specifically

around reducing 2008, 5006,

and 5007 errors

Set up 5011 SMS text alert to

contact Cepheid tech support

2Can GxAlert demonstrate

“Value for Money”?

Page 6: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can errors be

better managed?Can stockouts

be prevented?

Failing pressure sensor led to

5-week increase in error rates

Errors 2008, 2011

2Can GxAlert demonstrate

“Value for Money”?Can site selection

be optimized?

Page 7: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can GxAlert demonstrate

“Value for Money”?

Can errors be

better managed?Can stockouts

be prevented?

Good news is that better training

leads to fewer errors!

2Can site selection

be optimized?

Page 8: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can GxAlert demonstrate

“Value for Money”?

Can errors be

better managed?Can stockouts

be prevented?

Needs cartridges

Has more cartridges on

hand than they can use

before expiration

2Can site selection

be optimized?

Page 9: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can GxAlert demonstrate

“Value for Money”?

Can errors be

better managed?Can stockouts

be prevented? 2Can site selection

be optimized?

Page 10: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can GxAlert protect

MOH data ownership

and patient privacy?

Can an open

source software

be built?

Train in 1

hourEach install

<15 min

Hosted in-

country

June

2nd

3

Page 11: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Can GxAlert be a proxy

for measuring disease

burden?

Can we report

WHO indicators

automatically?

Self-configure

new indicators

GeneXpert Test Results

� By MTB

� By Rif

� By Age

� By Sex

� By DR Suspect

� By HIV status

� Custom…

4

Page 12: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Costs Related to GxAlert Pilot

Pilot

Installation 1hr Skype, free

Software Free

Hosting Free @ GxAlert

Security* Free

Modems** $20 ea

Connectivity** $5/mo/ea

*Assumes you already have anti-virus and firewall installed

**Paid directly to a local mobile operator of your choice

Page 13: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Costs Related to National Rollout

National Scale

Installation Depends

Software Free

Hosting Free @ GxAlert, or

hosted in country

Security* See below

Modems** See below

Connectivity** $15,000/yr up to

300 GeneXperts

*Assumes you already have anti-virus and firewall installed

**Paid directly to a local mobile operator of your choice

Page 14: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Abt Associates

Acknowledgements

� Nigeria FMOH

� CHAI

� PATH

� MSH

� USAID

� CDC

� Gates Foundation

� Cepheid

Page 15: 2. Takle GxAlert - Stop TB GxAlert.pdf · 2014. 12. 22. · Takle GxAlert. GxAlert. Open-source data connectivity for the GeneXpert. 6thAnnual WHO GLI Conference, Geneva Jeff Takle,

Open-source

MOH-owned data

Appropriate treatment, faster

Value for MoneySecure, patient privacy

Proxy for disease burden

QUESTIONS?

www.GxAlert.com