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    Selected Dynamic Innovation

    National Innovation Strategy

    Biotechnology

    29 April 2011

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    National Innovation Policy: Biotechnology

    Confidential Final Report Page 2

    Contents

    TABLE OF CONTENTS

    LIST OF EXHIBITS ...................................................................................................................... 3

    DISCLAIMER ............................................................................................................................... 4

    INTRODUCTION .......................................................................................................................... 5

    SECTOR DEVELOPMENT FOCUS ............................................................................................. 7

    CREATE REGIONAL CHAMPIONS .......................................................................................... 18

    TRANSFORMATION EXECUTION FRAMEWORK .................................................................. 21

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    Exhibit 1 Accelerating Revenue Growth through Innovative Transformation 6

    Exhibit 2 Benefits of Adopting Agricultural Biotechnology to the Rakyat and Business 7

    Exhibit 3 Intensifying Agricultural Biotechnology Development 10

    Exhibit 4 Benefits of Adopting Industrial Biotechnology to the Rakyat and Business 12

    Exhibit 5 Renewable Energy Potential in Malaysia 14

    Exhibit 6 Accelerating Industrial Biotechnology Development 15

    Exhibit 7 Suggested Criteria in Selecting High Potential Performing Companies 18

    Exhibit 8 Infrastructure Support Development 19

    LIST OF EXHIBITS

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    The publication of this report contains information in summary form and is therefore intended for

    general guidance only. It is not intended to be a substitute for detailed research or the exercise

    of professional judgement. Neither Unit Inovasi Khas (UNIK) nor the party assisting UNIK in

    the preparation of this can accept any responsibility for loss occasioned to any person as a

    result of any material in this publication. On any specific matter, reference should be made to

    the appropriate advisor.

    Exchange Rate Conversion

    MYR AUD RMB INR SGD KRW

    USD 1.0 3.5 1.09 6.83 46.45 1.39 1170.18

    DISCLAIMER

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    The Malaysian Government has identified biotechnology as one of the core technologies to

    accelerate the transformation of Malaysia into a knowledge-based economy and an

    industrialised nation by year 2020. For this purpose, the National Biotechnology Policy (NBP)

    was launched in 2005 to provide a development framework for the industry represented by

    agricultural, healthcare and industrial biotechnology sectors. The NBP is to be implemented

    over three phases: Phase I Capacity Building (2006-2010); Phase II Science to Business1

    (2011-2015); and Phase III Global Business (2016-2020). The biotechnology industry is

    expected to contribute 2.5% towards the national Gross Domestic Product (GDP) by 2010; 4%

    by 2015; and 5% by 20202.

    In 2010, a Malaysian Biotechnology Country Report 2009/2010 (Country Report) was launched

    to provide an overview of biotechnology industry development in Malaysia since 2005. The

    Country Report reported that the Malaysian biotechnology industry has recorded a total

    investment of USD1.3 billion (RM4.5 billion) by 2009. 57.8% of this investment was funded by

    the Government while the remainder was funded by private sector. The contribution of the

    biotechnology industry towards the GDP in 2009 was estimated at 2%. In terms of total

    employment, it was estimated that 54,000 people were employed in the life-science and

    biotechnology-related industry in 2009. The Country Report has set also out priority actions

    moving forward into Phase II of the NBP implementation.

    This study, as part of the development of the National Innovation Strategy, aims at re-prioritising

    certain focus areas and strategic actions in order to effectively accelerate revenue growth in the

    next five years. In addition, this study outlines priority policy measures that require immediate

    attention for effective transformation execution for results.

    1The original term in the NBP is Lab to Market2National Biotechnology Policy 2005

    INTRODUCTION

    Accelerating the Biotechnology Industry from Science to Business

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    Exhibit 1: Accelerating Revenue Growth through Innovative Transformation

    Policy Purpose Possible Policy Measures

    Capitalise on unique

    strengths forSector

    Development focus and

    provide competitive

    platform through right

    Infrastructure

    Development

    1. Intensify the application of new platform technologies in

    Agricultural Biotechnology development

    2. Accelerate the development of technology for effective

    implementation of green chemistry initiatives through

    Industrial Biotechnology

    Create Regional

    Champions

    3. Nurture High Potential Performing companies

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    Although Malaysian agriculture sector was the main economic contributor prior to 1990s, the

    agriculture sector is now the third engine of growth contributing to GDP and food production.

    Given Malaysias traditional strength in the agriculture sector and the countrys abundance of

    natural resources and land, the NBP has positioned agricultural biotechnology development as

    the first policy thrust. By 2009, agricultural biotechnology was the largest revenue generating

    sector, representing approximately 39% of total revenue contributed by the largest number of

    biotechnology companies (143 out of 349 companies)3. Besides NBP, the Third National

    Agricultural Policy (1998-2010) (NAP3) has identified biotechnology as the enabling tool to

    improve the national food security, and to ensure sufficient and sustainable food supply as wellas to generate economic gains. The Tenth Malaysia Plan (RMK-10) has also highlighted the

    adoption of biotechnology together with Information and Communication Technology and

    relevant technologies as the tools to revitalise the agriculture sector4.

    In addition, Malaysia, being one of the 12 mega biodiversity countries of the world, has over

    12,500 species of flowering plants and 1,100 species of ferns and fern allies; many of which are

    unique to Malaysia. There are over 286 species of mammals, 150,000 species of invertebrates,

    8,000 species of fish and countless lower order organisms like microbes, fungi and algae in

    Malaysia. Therefore, there is large potential in the unexplored biodiversity and a vast gene pool

    for Malaysia to capitalise on within the natural products, livestock and aquaculture focus areas.

    Exhibit 2: Benefits of Adopting Agricultural Biotechnology to the Rakyat and Business

    In a high income economy, the agriculture-

    based business can add significant value

    in the economic development

    A sustainable approach will result in an

    efficient and advanced agriculture sector

    development

    Increase in productivity through the

    selection and development of genotypes

    that correspond to commercially

    important traits in crops and livestock

    Reduce dependency on imported food

    and agriculture products

    Increase the income levels of farmers

    Provide opportunities for development

    3Malaysian Biotechnology Country Report 2009/20104Tenth Malaysia Plan (RMK-10)

    SECTOR DEVELOPMENT FOCUS

    1. Agricultural Biotechnology Development

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    In a high income economy, the agriculture-

    based business can add significant value

    in the economic development

    A sustainable approach will result in an

    efficient and advanced agriculture sector

    development

    (e.g. disease resistance, increased crop

    yield, enhanced nutritional value)

    Move up the value chain in the sector by

    enhancing scientific evidence for natural

    products

    Enhance value of companies in

    agriculture sector

    Gain access to global market with

    Malaysian products and services

    of young entrepreneurs

    Challenges

    One of the key challenges in agricultural biotechnology development is the ability to accelerate

    capacity and capability building in crop-related and livestock biotechnology. There is a need to

    continuously enhance technology to improve the value add and productivity of crops and

    livestock. Malaysian Biotechnology Corporation Sdn Bhd (BiotechCorp)s acquisition of a

    Marker Assisted Selection (MAS) platform technology from DNA LandMarks, a BASF Plant

    Science Company, will increase productivity of crops and livestock through enhancement of

    crop and animal breeding programme5. The MAS platform technology is expected to assist in

    the development of new applications in crops and livestock. Models for rice, watermelon and

    goats are readily available for development of application in related breeding programmes. The

    development of new applications in a wider range of crops and livestock would help Malaysia in

    establishing itself as a regional hub in molecular marker technology for agriculture.

    The natural products industry in Malaysia is still at an infancy stage as majority of small medium

    enterprise players have limited market and technical capabilities. Most natural products industryplayers are involved in the low-end market segments with limited standardisation of extracts

    using chemical and pharmalogical profiling. This poses a challenge for the industry players to

    penetrate the international markets. BiotechCorps acquisition of the Supercritical Fluid (SCF)

    platform technology from FeyeCon, Netherlands, is intended to enhance evidence-based

    5Malaysian Biotechnology Country Report 2009/2010

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    platform in developing natural products6. There are already 33 recipes for extraction of natural

    products that can be commercialised immediately. The platform technology will also be able to

    scale up commercialisation of extraction and production of novel bioactive compounds. By

    establishing the scientific evidence for natural products, Malaysia will be able to move up the

    value chain in producing nutraceuticals, over-the-counter drugs and ultimately botanical drugs.

    Rationale

    Malaysia remains a net importer of food. In 2008, Malaysia's food exports amounted to RM17.9

    billion, while imports amounted to RM28 billion7. Malaysia is highly dependent on imported

    intermediate food products due to the limited agricultural production and rising demands for

    many food products. Demand for food, especially for wheat-based products, livestock, dairy

    products, sugar and vegetables, is expected to continue to grow. Domestic production,

    however, cannot keep pace with the rising demand. Therefore, crop-related and livestock

    biotechnology development will be critical in addressing the countrys domestic needs,

    increasing the self-sufficiency levels and improving the balance of trade in major food

    commodities.

    As described earlier, the MAS platform technology is expected to enable the development of

    applications in crops and livestock allowing expansion of MAS breeding programmes. Crop-

    related biotechnology such as in vitro technology (e.g. plant tissue-culture for planting material

    production), plant genomics, molecular marker technology and biotechnology/genetically

    modified crops for plant improvement, are currently available and being implemented locally.

    Although assisted reproductive techniques need enhancement, the use of current assisted

    reproductive techniques should be continued in order to continuously improve livestock

    productivity.

    Given Malaysias biodiversity uniqueness, it is also critical for the country to leverage on its

    natural resources in order to move up the value chain in agriculture development. As described

    earlier, the acquisition of the SCF platform technology is aimed at enhancing the evidence-

    based platform in developing natural products.

    6Malaysian Biotechnology Country Report 2009/20107Malaysian Industrial Development Authority (MIDA)

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    There is a large and growing global demand for novel compounds and active ingredients from

    natural products used in the production of food ingredients, functional food, nutraceuticals,

    cosmeceuticals and botanical drugs (phytomedicine). Natural products can also be developed

    into health supplements, functional foods and cosmetics to cater to the growing health and

    wellness market. The global nutraceuticals market is growing as large companies and

    Multinational Corporations such as Monsanto, DuPont, Abbott Laboratories, Johnson &

    Johnson, Novartis, Metabolex and Genzyme Transgenic are channeling significant amount of

    investments into the discovery of nutraceuticals8.

    Exhibit 3: Intensify Agricultural Biotechnology Development

    Policy Purpose Possible Policy Measures

    Scale up Capacity

    and Capability of

    Existing

    Companies

    There is a need to scale up capacity and capability in agriculture sector

    through biotechnology development. In order to expedite the

    development of existing companies in agriculture sector, the following

    measures are proposed:

    As outlined in the Country Report, implement a suitable business

    model to leverage on the newly acquired platform technologies.

    BiotechCorp, being the platform technology owner, will work in

    collaboration with the custodians of the platform technologies, namely

    Malaysian Agricultural Research and Development Institute (MARDI)

    for the MAS platform technology and Universiti Putra Malaysia (UPM)

    for the SCF platform technology.

    o BiotechCorp will have overall responsibility for the

    commercialisation of the applications by promoting the

    platform technologies to existing companies.

    o The custodians will undertake relevant development and

    validation efforts to commercialise the applications.

    Align all innovation development (including use of biotechnology)

    objectives and commitment from all related Government ministries

    and agencies to implement the policy thrusts from NAP3 in order to

    place focus on areas that will generate significant results in the next

    five years, e.g. intensify large-scale food production by private sector.

    8Malaysian Biotechnology Country Report 2009/2010

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    Policy Purpose Possible Policy Measures

    Accelerate

    Sustainable

    Growth

    For sustainable growth in this sector, specific incentives are needed in

    order to intensify strategic partnerships between existing large

    Government-linked (such as Sime Darby, Felda, CCM) or private (such

    as IOI, United Plantation) companies with high potential agricultural

    biotechnology companies.

    Provide existing local market access opportunities which can be

    extended to global market access

    Enable sustainable supply of feedstock or land for production of

    crops, livestock or natural products

    Provide relevant facilities or infrastructure support to

    biotechnology companies to grow

    Such partnerships will also enable the implementation of Extended

    Supply Chain Model (eSCM) model (e.g. industrialisation of food system

    through high degree of coordination, a large and consolidated processing

    sector with organised retailers).

    Intensify Global

    Marketing

    Given Malaysias reputation in agriculture sector, it should leverage on

    this reputation to develop global marketing strategy for agricultural

    biotechnology.

    Promote Malaysia as a regional hub for the MAS and SCF

    platform technologies to enable regionalisation and gloablisation

    of Malaysian products and services

    Streamline activities undertaken by different marketing and

    promotional institutions (e.g. FAMA, MARDI, Biotechcorp,

    MATRADE) to enhance marketing spend effectiveness

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    At the Copenhagen World Summit on Climate Change, Malaysia committed to reducing its

    carbon emission by up to 40% by 2020. To uphold its commitment, the Ministry of Energy,

    Green Technology and Water (MEGTW) is expected to intensify its efforts to execute green

    initiatives in the country. Industrial biotechnology development will be critical to provide green

    initiative solutions to environmental issues, such as municipal waste management and

    alternative renewable energy like the production and utilisation of biofuel as compared to fossil

    fuels. Furthermore, Malaysia should continue to leverage on its abundance of natural resources

    and biomass to develop industrial biotechnology for green technology application.

    By 2009, there were 72 industrial biotechnology companies (out of 349 companies) contributing

    approximately 30% of total revenue in the biotechnology industry9. One of the key drivers for

    industrial biotechnology is the presence of an immediate market, i.e. the oil palm sector.

    Malaysia is the second largest producer and the largest exporter of palm oil. Hence, industrial

    biotechnology activities tend to revolve around this sector, as in the case for companies

    involved in bioremediation (for Palm Oil Mill Effluent), fine and specialty chemicals

    (oleochemicals and its derivatives from downstream palm oil processing), and biofuel (from

    olein, crude palm oil, sludge oil and effluent ponds). Priority green initiatives will be as follows:

    a) To implement a green chemistry initiative (biofuel, bioremediation)

    b) To apply advances in bioprocessing technology for fine and specialty chemicals and

    biomaterials (biopolymer)

    Exhibit 4: Benefits of Adopting Industrial Biotechnology to the Rakyat and Business

    In a high income economy, businesses will

    be environment-friendly with sustainable

    economic development

    Sustainable environment-friendly

    solutions for the well-being of Rakyat

    Enable achievement of carbon emission

    reduction commitment

    Promote healthy living environment

    Able to have access to environment-

    9Malaysian Biotechnology Country Report 2009/2010

    SECTOR DEVELOPMENT FOCUS

    2. Industrial Biotechnology Development

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    In a high income economy, businesses will

    be environment-friendly with sustainable

    economic development

    Sustainable environment-friendly

    solutions for the well-being of Rakyat

    Provide opportunities for significant cost

    reduction in all sectors

    Enhance effectiveness of resource

    utilisation

    Create new economic value that is

    sustainable

    Enable greater leverage on Malaysias

    core competencies in manufacturing

    friendly solutions, e.g. alternative

    energy

    Able to instill greater awareness of

    environment-friendly solutions among

    future generation

    Reduce dependency on depleting fossil

    fuel

    Challenges

    Although the Small Renewable Energy Programme (SREP) aimed to generate 5% or 600MW of

    the countrys electricity from renewable energy by 2005, only 0.3% was achieved10. The slow

    progress of commercialising renewable energy can be attributed to several factors. One of the

    main factors is the lack of a clear policy framework to promote the usage of renewable energy in

    the country. This results in insufficient public awareness and promotion on the importance of

    environment sustainability through green technology. Only large corporations with significant

    carbon emissions will adopt such practices. Smaller companies with lesser carbon emissionmay find it relatively time consuming and not cost effective to invest in such practices.

    The prohibitive pricing of renewable energy also discourages households and business owners

    to adopt the technology. Additionally, the capital cost of renewable energy implementation is

    high as compared to the relatively low sales price of electricity (17 cents/kWh) which makes

    production of renewable energy considered unviable.

    Biofuel is one of the alternative sources of energy, and Malaysia has already installed capacity

    of close to two million tonnes of palm biodiesel as of 2009. However, in Malaysia, theproduction of first generation biofuel is facing two key challenges, namely, the high price of palm

    oil and the food versus fuel controversy. Therefore, there is a need to promote development of

    second generation biofuel which epitomises the concept of turning waste into wealth. This

    10Renewable and Sustainable Energy Reviews 14 (2010)

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    would provide enormous potential for Malaysia given the amount of harvestable biomass that is

    produced in the palm oil plantation sector.

    Besides biofuel, there are several barriers to the development and adoption of bioremediation in

    Malaysia including the lack of integrated research from multidisciplinary fields, limited funding,

    and inadequate tools and infrastructure to aid research on bioremediation. As for biopolymer

    development, thereis currently a technology gap in converting agriculture waste into bioplastics

    and biodegradable plastics.

    Rationale

    Surging demand for energy, escalating energy prices, growing energy security concerns and

    scarcity of natural resources are factors driving Government and companies to work harder to

    diversify their energy portfolio mix. As outlined in the SREP, it is therefore critical to identify

    environment-friendly alternative sources of energy to meet the growing local and global

    demand. Biofuel offers a sustainable and viable alternative source of energy that will save on

    greenhouse gas emissions and reduce dependency on rapidly depleting fossil fuels.

    Given Malaysia is the worlds second largest producer and top exporter of palm oil, it has the

    comparative advantage in the production of biodiesel from palm oil biomass. As shown in

    Exhibit 5, with the abundance of palm oil mills and other resources, renewable energy, mainly

    biofuel and biogas will have huge potential for development in Malaysia.

    Exhibit 5: Renewable Energy Potential in Malaysia

    Renewable Energy Potential (MW)

    Hydropower 22,000

    Mini Hydro 500

    Biomass/Biogas (palm oil mill waste) 1,300

    Municipal solid waste 400

    Solar PV 6,500

    Wind Low wind speedSource: Energy Commission Malaysia 2009

    The National Biofuel Policy, which was launched in 2006, aims at positioning Malaysia as a

    major global biodiesel producer. The Government has mandated all Government diesel-

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    powered vehicles to start using biodiesel in February 2009. The legislation to mandate the use

    of B5 diesel will be passed and enforced in June 201111.

    Besides biofuel, bioremediation is one of the green initiatives that can help reduce the carbon

    footprint and environmental impact of Malaysias large manufacturing sector. The global

    bioremediation market in 2009 was estimated at USD 30 billion (RM 105 billion) and Malaysias

    bioremediation market is estimated at USD 102.9 million (RM 360 million) per annum.

    Furthermore, through the Clean Development Mechanism (CDM), Malaysia can benefit from

    investments in the greenhouse gas emission reduction projects, especially in the areas related

    to the palm oil sector.

    Biopolymer generally refers to bioplastic and its applications are also seen in the production of

    biodegradable plastic. There is growing demand worldwide for the use of bioplastic and

    biodegradable plastic to replace some types of traditional petroleum-based plastic, especially in

    the packaging industry. Major bioplastics include starch-based, polyhydroxylalkanoate and

    polylactic acid. The global market for lactic acid and its derivatives is predicted to have a

    compounded annual growth rate of 15%. The potential market in bioplastic applications, for

    instance polylactide, is expected to reach three to five million tonnes by 202012. This estimate is

    based on the increasing awareness of the environment, health and safety among consumers

    and businesses. Being natural products, lactic acid and its derivatives can be used safely

    without threat to the environment.

    Exhibit 6: Accelerating Industrial Biotechnology Development

    Policy Purpose Possible Policy Measures

    Accelerate

    Technology

    Development to

    Build Capacity and

    Capability

    Although Malaysia has the resources and competencies in industrial

    biotechnology development, there are technology gaps in the priority

    segments, biofuel, bioremediation and biopolymer. It is therefore critical

    for Government to allocate adequate funds to accelerate technology

    development for biofuel, bioremediation and biopolymer.

    Provide green investments and incentives with related policies to

    boost the development and commercialisation of renewable

    energy related technology, e.g. second generation biofuel

    112011 Budget Speech (2010)12Malaysian Biotechnology Country Report 2009/2010

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    Policy Purpose Possible Policy Measures

    Enable acceleration of technology development through

    acquisition of suitable foreign technologies or companies

    Facilitate strategic partnerships and collaborations with foreign

    affiliates to accelerate technology transfer and market access

    o Accelerate processing of Malaysian work visas for foreign

    expatriates, to efficiently bring in qualified foreign skills

    and expertise

    o Accelerate processing of approval of foreign participation

    and all related documentation

    Implement Green

    Economy Policies

    and Regulations

    Enforcement of Government policies and regulations tend to be more

    effective to support the growth of a green economy. Such policies and

    regulations can be in the forms of incentives (such as tax allowance,

    subsidies, matching grants), penalties or mandates. The Government

    could:

    Mandate the use of biofuel and biodegradable packaging

    materials

    Offer incentives for the treatment of solid waste and wastewater

    using bioremediation

    Offer incentives for adoption of environment-friendly solutions

    Impose penalties on companies with high carbon emission

    Provide subsidies to renewable energy players or phases out

    subsidies of existing energy players

    Mandate feedstock pricing caps, e.g. cap prices of palm oil

    biomass

    Promote use of green and hybrid vehicles by reducing import

    duty and sales tax

    Existing policies and regulations need to be reviewed regularly to

    ensure their effectiveness. Furthermore, the Government policies and

    regulations need to be holistic and coordinated. For example,

    Government funding allocation to the various Government

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    Policy Purpose Possible Policy Measures

    ministries and agencies will be made based on green economy

    policies and guiding principles

    All Government ministries and agencies to adopt use of

    renewable energy and to achieve certain levels of carbon

    emission reduction

    Intensify

    Sustainable

    Profitable Growth

    Strategic partnerships among the various stakeholders in this sector are

    critical for sustainable profitable growth.

    Government and Government-linked companies to provide the

    private sector, e.g. emerging high potential industrial

    biotechnology companies, with the opportunities to supply green

    products or services

    Government-linked companies to provide emerging high

    potential industrial biotechnology companies with:

    o Local and global market access (i.e. distribution network)

    o Supply of required feedstock

    o Production facilities

    o Collaboration in technology application development and

    commercialisation

    In addition, the eSCM model can be implemented through such

    strategic partnership.

    Intensify Global

    Marketing

    Given Malaysias strengths in biofuel, there is a need to intensify global

    marketing to promote Malaysia as the regional hub for biofuel. The

    regional hub will eventually extend to cover bioremediation and

    biopolymer. Similar to the policy measure described earlier, there is a

    need to streamline activities undertaken by different marketing and

    promotional institutions to enhance marketing spend effectiveness.

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    In the next five years of policy measure execution transformation, it is critical to showcase high

    impact successes. Priority policy measures identified will require accelerated execution

    approach to enable priority biotechnology businesses to excel and generate high impact results.

    High impact successes tend to be defined in terms of economic growth contribution and benefits

    generated for the rakyat. Economic growth contribution will be measured on the basis of

    companys business performance. As described earlier, specific segments of agricultural and

    industrial biotechnology sectors will be placed greater emphasis to generate quick and high

    impact results.

    Therefore, identification of high potential performing companies will be critical for nurturing and

    development. Exhibit 7 provides suggested criteria to be considered in selecting high potential

    performing companies. The selected companies will be put through a transformation execution

    programme in order to achieve pre-determined accelerated growth rate.

    Exhibit 7: Suggested Criteria in Selecting High Potential Performing Companies

    Priority segments Supports countrysagendas

    Companycharacteristics

    Agricultural Biotechnology: Crop-related Livestock Natural products

    Industrial Biotechnology:

    Biofuel Bioremediation

    Biopolymer

    Regional and globalexpansion capability

    Knowledge economy Green technology/

    Environment-friendly/carbon credit reduction

    High potential multipliereffects with holistic

    economic linkages High impact potential

    growth rates Sustainability- product

    attractiveness

    Competent entrepreneursand management team

    Established profile with

    proven track record Successful business

    model

    Opportunities forinnovative business

    model Opportunities for capacity

    and capability expansion Opportunities for product

    innovation

    1 2 3

    Target companies in the Early Growth Production and Commercialisation stage

    CREATE REGIONAL CHAMPIONS

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    The proposed policy measures will form part of the transformation execution programme that

    aims at developing the priority segments of agricultural and industrial biotechnology sectors. In

    addition, the following infrastructure support policy measures are proposed for consideration:

    Exhibit 8: Infrastructure Support Development

    Policy Purpose Possible Policy Measures

    Attract and

    Develop Adequate

    Pool of Expertise

    There is a need to ensure collaboration between the different agencies,

    Talent Corporation, BiotechCorp and GreenTech Malaysia to attract and

    develop a pool of expertise required for agricultural and industrial

    biotechnology development.

    The development of the expertise will help address skill shortages faced

    by the biotechnology companies. Priority will be given to therequirements of the selected companies to be nurtured.

    Promote

    innovative funding

    Adequacy and availability of funds are critical in nurturing the selected

    companies. Given the lack of private funding for pre-commercialisation

    and commercialisation, continued Government support in the form of

    public funding is still required to continuously build industry confidence.

    Promotion and awareness programmes should continue to create greater

    understanding of the industry amongst the financier and investor

    communities.

    Strengthen public funding through:

    o Focused funding schemes (in the forms of grants, convertible

    soft loans) for pre-commercialisation and commercialisation

    stages, especially second round funding

    o Formation of special venture fund with pre-defined investment

    focus that is in line with the innovation strategic intent

    Incentivise financial institutions and development financial

    institutions to allocate loans for priority biotechnology sectors

    Promote local and foreign venture capitalists to set up new

    biotechnology venture fund(s) by matching with Government

    funding

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    Policy Purpose Possible Policy Measures

    Harmonise

    Government

    Policies

    Government plays a significant role in creating a conducive ecosystem

    for entrepreneurship and innovation to support the development of

    biotechnology industry:

    Align and harmonise all related Government blueprints, policies

    and implementation roadmaps

    Clearly define and align the roles of the various ministries and

    agencies involved to address overlaps

    Encourage collaboration among Government ministries and

    agencies for effective resource utilisation

    In addition, additional targeted policy measures will be identified and customised to address

    certain specific requirements of any selected high potential performing company for the

    company to succeed.

    Appropriate key performance indicators (KPIs) and targets will be set for each selected high

    potential performing company in order to track performance of each company. Specific

    innovation transformation action plans will be developed in order to achieve the targets set.

    Upon selection of high potential performing companies, the following key tasks will need to beundertaken for each selected company:

    Review business plan in detail and establish new measures and targets

    Identify key resources and enablers required and key barriers that need to be overcome

    Assess policy measures and work out appropriate details required for implementation

    Customise policy measures appropriately and develop new policy measures, if any

    Update business plan with KPIs, targets, milestones and timelines

    Upon agreement of the business plan moving forward, each company is expected to start

    implementation without any delay.

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    Effective transformation execution will be critical to generate expected outcomes. The proposed

    transformation execution framework will set out a mechanism for co-ordinating the

    implementation of proposed policy measures, provide broad guidelines for regular

    transformation monitoring and progress reporting, and describes the communication programme

    to disseminate and obtain feedback on the transformation progress.

    UNIK is proposed to set up a Transformation Management Office (TMO) to oversee progress of

    the transformation execution. The overall progress of the implementation process will be

    closely monitored by TMO to ensure that all policy measures and individual company business

    plans are being implemented within the stipulated timelines.

    Proper progress monitoring is aimed at ensuring that transformation execution programme is

    implemented within their stipulated timelines. Any delays will be carefully reviewed to take into

    account their effects on other dependent or associated policy measures or actions. Where

    timelines need to be adjusted, other affected policy measures or actions will be reviewed and

    rescheduled accordingly.

    Apart from monitoring the timely completion of the various actions, it is necessary to develop

    specific KPIs and targets to gauge the effectiveness of transformation execution programme in

    accelerating revenue growth. As described earlier, KPIs and targets will be set for each

    selected company to track performance.

    To provide a timely, pragmatic and systematic response to new developments and changing

    circumstances in the Malaysian economy, the transformation execution programme objectives

    will be regularly reviewed and updated to ensure their continued applicability. With this in mind,

    various stakeholder engagement sessions will be conducted periodically to ensure

    comprehensive review of the overall transformation execution programme.

    Therefore, the TMO will also need to put in place a coordinated communications programme for

    stakeholder engagement in order to obtain regular feedback on the transformation execution

    programme.

    TRANSFORMATION EXECUTION FRAMEWORK