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June 26 – 28, 2014, Milano, Italy

International Congress of the International Society for Medical Shockwave Treatment17th

June 25, 2014: Instructional Certification Course

Programme

Patronage requested

Comune di Milano

Regione Lombardia

Ordine dei Medici Chirurghi e Odontoiatri di Milano

Aknowledgments

A special thank for the collaboration to:

Office of the International Society for Medical Shockwave Treatment (ISMST)

AUVA

Eugenio Maggioni for the pictures (Leonardo Museum, Milan)

Rudy Amisano (Teatro alla Scala)

WelcomeDear colleagues,dear friends of the ISMST,

It is a great honor and a pleasure to invite you all to the 17th International Congress of the ISMST, that will be held in Milan from 26 to 28 June 2014, at the Congress Center of Humanitas Research Hospital. On the 25 June 2014, the Instructional Certification Course will take place, held by ISMST certified instructors.

The Program will include Basic Science and Clinical Practice, with classic common indications in bone and soft tissue pathologies. A special emphasis will be given to new applications, focused both on Regenerative Medicine and those therapeutic indications still in the experimental phase.

We will have the opportunity to share many ideas, all our experiences, new scientific hypothesis, thera-peutic perspectives, and to clarify some doubts. Moreover, in the Meeting of Milan 2014, we will welcome some Guest Scientific Societies. Their most representative members, will be invited to actively participate - as mediators - in our scientific sessions.

Abstract submission expired on March 31, and we are glad to say that we received highly interesting papers from various topics in shockwave therapy. It is also a great pleasure to announce to you, also for this year’s meeting, an award endowed with Euro 500 for the best paper presented. The award will be handed over on Saturday 29 June 2014, during the Closing Ceremony.

A Medical Fair will take place during the conference, where state-of-the-art development and technical standards of extracorporeal shockwave equipment will be presented. We are grateful in advance to all the industries that are going to support our international ISMST Congress in 2014.

We are also pleased to cordially invite and welcome you to some special Social Events, which will make you feel and live the typical atmosphere of Milan, both modern and of the old days as well. These particular moments will be occasions for sharing all together, with your families as well, some very pleasant and unforgettable moments of fun, accompanied by good food & wine, and welcomed by the typical and charming Italian hospitality, that will make you feel special guests and will make you want to come back… Please, do not miss the opportunity to enjoy Milan with all its different attractions!

On behalf of the International Society for Medical Shock Wave Treatment and the Organizing Committee, I am looking forward to welcome you all in Milan!

Yours sincerely,

Maria Cristina D’Agostino President of ISMST

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General information

In cooperation withAUVA (Allgemeine Unfallversicherungsanstalt, Austria)

SITOD (Societa’ Italiana Terapia con Onde D’Urto) SFOCAL (Société Française pour les Ondes de Choc sur l’Appareil Locomoteur) DIGEST (Deutschsprachige Internationale Gesellschaft für Extrakorporale Stoßwellentherapie) AK-ESWT Österreich (Arbeitskreis ESWT der Österreichischen Gesellschaft für Orthopädie und Orthopädische Chirurgie) ONLAT (Federacion Iberoamericana de Ondas de Choque en Medicina) SBTOC (Sociedade Brasileira de Terapia por Ondas de Choques) SGST (Schweizerische Gesellschaft für Stoßwellen-Therapie) SVOCHUM (Sociedad Venezolana de Ondas de Choque de Uso Medico) TOCH (Capitulo Argentino de Terapia por Onda de Choque) OCC (Ondas de Choque de Colombia) SETOC (Sociedad Española de Tratamientos con Ondas de Choque) SEOCE (Sociedad Espanola de Ondas de Choque Extracorporeas)

VenueCentro Congressi Humanitas IRCCS Humanitas Research Hospital Via Manzoni 113, Rozzano, 20089 MI

Congress languageThe congress language is English

OrganizerInternational Society for Medical Shockwave Treatment (ISMST) Ebelsberger Schlossweg 5 4030 Linz, Austria

Table of contents

Patronage requested.. .............................................................................. I

Acknowledgments ................................................................................... I

Welcome ....................................................................................................1

General information ................................................................................2Venue ..............................................................................................2Congress language ..........................................................................2Organizer ........................................................................................2In cooperation with ........................................................................2Guest societies ................................................................................4Organizing committee ....................................................................5Scientific organization ....................................................................6Congress secretariat ........................................................................6Opening hours of the registration desk ..........................................6

Sponsors ....................................................................................................7

Programme at a glance ............................................................................8Wednesday June 25, 2014 ..............................................................8Thursday June 26, 2014 .................................................................8Friday June 27, 2014 ......................................................................9Saturday June 28, 2014 ..................................................................9

Venue and floor plan .............................................................................10Humanitas congress center ...........................................................10Halls and main technical equipment ............................................11Exhibition areas ............................................................................12Architectural features ...................................................................12Maps & directions .........................................................................12

Scientific programme ............................................................................14

Social events and programs..................................................................26ISMST Welcome Party ..................................................................26Presidential Dinner .......................................................................27Serravalle Outlet Village ...............................................................28Guided visit to Como ....................................................................28Guided visit in Milano ..................................................................29

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Guest societies

ISMuLT (Italian Society of Muscle, Ligaments and Tendons)

InSMuLT (International Society of Muscle, Ligaments and Tendons)

CORTE (Conferenza italiana per lo studio e la Ricerca sulle ulcere, piaghe, ferite e la riparazione Tessutale)

SIGASCOT (Società Italiana del Ginocchio Artroscopia Sport Cartilagine Tecnologie Ortopediche)

SPARK OF EVIDENCEWe push medical progress further – for a better quality of life.

ORTHOPEDICS WOUND CARE UROLOGY

Organizing committee

President M. Cristina d'Agostino (Italy)

Executive Board Vinzenz Auersperg (Austria) Roberto Frairia (Italy) Markus Gleitz (Luxemburg) Carlos Leal (Colombia) Rainer Mittermayr (Austria) Sergio Russo (Italy) Wolfgang Schaden (Austria) Richard Thiele (Germany)

International Scientific Board Jose’ Aid (Brazil) Ernesto Amelio (Italy) Manuel Branes (Chile) Paolo Buselli (Italy) Karin Freitag (Spain) John Furia (United States) Ludger Gerdesmeyer (Germany) Leonardo Guiloff (Chile) Daniel Moya (Argentina) Ana Claudia Souza (Brazil) Ching Jen Wang (Taiwan)

National Scientific Board Elena Abati Sergio Gigliotti Claudio Guerra Gianluca Melegati Luigi Messuri Biagio Moretti Maria Cristina Ottone Stefano Respizzi Pietro Romeo Raoul Saggini Elisabetta Tibalt Mariachiara Vulpiani

Congress Secretaries Catherine Auersperg (Austria) Valentina Balconi (Italy) Amra Causevic (Austria)Ursula Hogn (Austria) Brigitte Schmitt-Tegge (Germany)

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Scientific organizationISMST Office Ebelsberger Schlossweg 5 4030 Linz, Austria Phone: +43 (732) 30 23 73 Fax: +43 (732) 30 33 75 E-mail: [email protected]

www.ismst.com

Congress secretariatCongress Centre Humanitas Research Hospital via Manzoni 56, Rozzano 20089 (MI) Tel: +39 02.82242369 Fax: +39 02.82246718 E-mail: [email protected]

www.humanitasedu.it

Opening hours of the registration desk

Wednesday, 25 June: ................ 07:30 – 18:00Thursday, 26 June: ................... 07:30 – 18:00Friday, 27 June: ........................ 07:30 – 18:00Saturday, 28 June: .................... 08:00 – 14:00

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pictures: Title page ...............©MontanNito Page I ....................©LHOON Page 1, 2&22 .........©Eugenio Maggioni Page 5 & 7 .............©Lorenzclick Page 6 ....................©marinamartis ....................©stepaganini Page 9 ....................©FromTheNorth Page 10, 11&12 .....©humanitas Page 18&19 ...........©gi@nnib Page 25 ..................©Rudi Amisano Page 26 ..................©Ristorante Memo/francesco magni Page 27 ..................©lucnix.be ..............................©Eugenio Maggioni Page 28&29 ...........©materiaprima

Promoting members

BTL Industries Ltd.Dornier MedTech Europe GmbHEMS Electro Medical SystemsGuanghzou Longest Co. MTS Medical UGRichard Wolf GmbHSTORZ MEDICAL AGZimmer MedizinSysteme GmbH

Elvation Medical GmbH Tur Plus GmbH UTC

Local sponsors

Bauernfeind GmbH & Co.LaborestMatek Group S.R.L.

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Programme at a glance

Wednesday, June 25, 2014

07:30 – 18:00 Registration 08:00 – 16:30 Instructional Certification Course

16:30 – 19:00 Managing Board Meeting

Thursday, June 26, 2014

07:30 – 18:00 Registration

07:30 – 18:00 Industrial exhibition

08:20 – 08:50 Opening ceremony – Welcome

08:50 – 11:20 Session 1 ESWT Basic Research I

11:20 – 11:40 Coffee break and exhibition

11:40 – 13:40 Session 2 Tendon I

13:40 – 15:00 Lunch break and exhibition

15:00 – 16:25 Session 3 Bone I


16:45 – 18:05 Session 4 Bone II

18:30 ISMST AGM (Annual General Meeting)

20:30 ISMST Welcome Party at Memo Restaurant

Programme at a glance

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Friday, June 27, 2014



08:00 – 10:15 Session 5 ESWT Basic Research II


10:35 – 12:50 Session 6 Tendon II


14:00 – 16:00 Session 7 Tendon III


16:15 – 17:15 Session 8 Urology

17:15 – 18:15 Session 9 Cartilage

16:30 – 18:00 ISMST Industrial Meeting

20:30 Presidential Dinner at Museo della Scienza e della Tecnica di Milano

Saturday, June 28, 2014



08:30 – 10:05 Session 10 Neurology


10:25 – 11:40 Session 11 Skin I

11:40 – 13:10 Session 12 Skin II

13:10 – 14:00 Closing ceremony

The 17th ISMST Congress will be held in Milan (Rozzano) at the: Congress Center of the Humanitas Research Hospitalwww.humanitas.it

Via Manzoni 113 20089 – Rozzano Milan Italy

Humanitas Congress Center

The Congress Center of Humanitas Research Hospital is located nearby Milan, close to the main motorways, and is the ideal place where events, congresses, training courses and company meetings can be held. Humanitas Congress Centre is settled by Humanitas Research Hospital (Building 2) – general hospital and research centre (IRCCS) – acknowledged by the Ministry of Health and by Regione Lombardia, as one of the centres which outstand for the quality of its cares and the capacity to transfer the innovation and research results into the daily hospital activity.

The main part of the Congress Center is located inside the Research and Didactics Center (Building 7), which also houses the University of Milan, Faculty of Medicine, Nursing and Biotechnology. It features 11 multifunctional spaces with capacity from 20 to 500 seats, exhibition areas, audio-video technologies and all additional services most innovative in the industry.

In order to satisfy any kind of needs as far as congress and training are concerned, the Congress office of the Center supplies a consultancy service able to offer an organization support and an all-encompassing flexibility in managing any kind of event to its customers.

Venue and floor plans

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Halls and main technical equipment

The halls of Humanitas Congress Centre are distributed on two different areas: (Building 2 and Building 7) about 150 meters far from one another, that can be easily reached on foot through a dedicated walkway.

The 17th ISMST Congress will be held at the Building 7 (Research and Didactics Centre), composed of different modular halls: Hall E (230 seats); Hall F (90 seats); Hall G (50 seats); Halls E + F + G (460 seats).

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Exhibition area

The areas of Humanitas Congress Centre can host any kind of exhibitions: different sizes of commercial boots and even more complex settings, for any kind of event. The flexibility of the exhibition areas allows to easily fit the spaces to the different needs. All exhibition areas are equipped with telephone line, wi-fi coverage, electric supply and illumination.

Architectural features

The architecture outside the University Research and Didactics Centre, projected designed by James Gowan, combines simple and clean, horizontal and vertical volumes, with different sizes and shapes. Birchwood boiserie is a main feature of the meeting rooms and helps controlling the acoustics. The lighting appliances, fully embedded in the architectural structure, privilege soft light optics, without dazzlement and direct emissions.

Maps & directions

Humanitas Congress Center is not equipped with the hotel inside its structure. For this reason an agreement was made, at a special rate, with the Atahotel Quark – Milan, a good hotel nearby (please visit the section Book Hotel for detailed informations and booking).

Both the Congress Center and the Atahotel Quark are well-connected each other and with the center of Milan, by public transports, the same used by the patients of the hospital.

A special service of bus – shuttles will be made available for the congress participants during the days of the Meeting. Moreover, from the Congress Center (and the Atahotel Quark as well), within a short time, by taxi, you can easily reach the closest Metro Station, towards the Center of the city.

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Wednesday, June 25, 2014

08:00 Introduction 10’ Dr. Markus Gleitz (Luxembourg)

08:10 Physical Principles 20’ Dr. Vinzenz Auersperg (Austria)

08:35 Biological Principles 20’ Dr. Wolfgang Schaden (Austria)

09:00 Principles of Shockwave Application 15’ Dr. Markus Gleitz (Luxembourg)

09:20 Demonstration of Devices 25’09:45 Break 15’10:00 Approved Standard Indications 1: Tendinosis Calcarea 15’ Prof. Dr. Ludger Gerdesmeyer (Germany)

10:20 Approved Standard Indications 2: Lateral epicondlitis 15’ Dr. Mariachiara Vulpiani (Italy)

10:40 Workshop 20’11:00 Approved Standard Indications 3: Plantar Fasciitis 15’ Dr. Paolo Buselli (Italy)

11:20 Approved Standard Indications 4: Achilles Tendinopathy 15’ Dr. John Furia (USA)

11:40 Workshop 20’12:00 Empirically-Tested Indications 15’ Dr. Martin Ringeisen (Germany)

12:20 Exceptional and Experimental Indications 20’ Prof. Dr. Sergio Russo (Italy)

12:45 Lunch Break 75’14:00 Myofascial Treatment 25’ Dr. Markus Gleitz (Luxembourg)

14:30 Bone Indications 20‘ Dr. Wolfgang Schaden (Austria)

14:55 Skin Indications 20’ Prof. Dr. Carlos Leal (Columbia)

15:20 Workshop 20’15:40 Socio-Political Issues 15’ Dr. Sergej Thiele (Germany)

16:10 Multiple Choice Test – Certificates 20’16:30 End of the Workshop

After each presentation 5 minutes of discussion

ISMST Instructional Certification Course ESWT

Organization: Dr. W. Schaden (Austria) Dr. M. Gleitz (Luxembourg)

Programme: 08:00h – 16:30h

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14


08:50 – 11:20 ESWT Basic Research I Session 1

Chair: D'Agostino M. Cristina – Italy Gerdesmeyer Ludger – Germany Mittermayr Rainer – Austria

07:30 – 18:00 Registration & Industrial exhibition08:20 – 08:50 Opening Ceremony Dr. M. Cristina d'Agostino (Milan) – ISMST President Dr. Markus Gleitz (Luxemburg) – ISMST General Secretary Dr. Ernesto Amelio (Verona) – SITOD President Dr. Sergio Russo (Naples) – Italian ISMST Senator Dr. Roberto Carlo Rossi (Milan) – OMCeO President (Medical Association of Milan)

Session time

Session title Abs-tract Nr.

08:50 – 09:15OPENING LECTURE – Mechano Trasduction:

a Lesson From Ancient TimesBrañes Manuel, Santiago, Chile

09:15 – 09:30 KEYNOTE LECTURE: From Mechanotransduction to Shockwave BiologyFrairia Roberto, Turin, Italy

09:30 – 09:40 Influence of Different In-Vitro Setups on Shockwave Treatment Parameters – a Guide for More Comparable ResultsDietz-Laursonn Kristin, Aachen, Germany

1

09:40 – 09:50 Combination of ESW and Doxorubicin-loaded Nanobubbles: Anti-Tumor Effects in Anaplastic Thyroid CancerMarano Francesca, Turin, Italy

2

09:50 – 10:00 Shockwave Treatment Upregulates Podoplanin Expression in Lymphatic Endothelial CellsRiedl Sabrina, Vienna, Austria

3

10:00 – 10:10 A Development of Biological Reparative Model in Human Tendon Derived From Fibroblasts Healing Process With Unfocused ESWTSaggini Raoul, Chieti, Italy

4

10:10 – 10:20 Shockwave Treatment Promotes the Expression of Alox15 in Pro-Resolving MacrophagesSukubo Naths Grazia, Milan, Italy

5

10:20 – 10:30 Shockwave Therapy as a Component of Multimodal Regenerative Medicine in HorsesMcClure Scott, Iowa, USA 6

10:30 – 10:45 KEYNOTE LECTURE: Macrophages at the Cross-Road Between Inflammation and RegenerationLocati Massimo, Milan, Italy

10:45 – 11:00 KEYNOTE LECTURE: New Findings in Experimental Shockwave Science – Summary of the Basic Research Meeting in FrankfurtHolfeld Johannes, Innsbruck, Austria

11:00 – 11:20 Discussion



11:40 – 13:40 Tendon I Session 2

Chair: Balzarini Luca – Italy Auersperg Vinzenz – Austria Moretti Biagio – Italy

Session time


11:40 – 11:55 KEYNOTE LECTURE: New Biological Strategies for TendinopathiesVolpi Piero, Milan, Italy

11:55 – 12:10 KEYNOTE LECTURE: UTC – A Novel Tool for Management of TendinopathiesVan Schie Hans, Amsterdam, Netherlands

12:10 – 12:20 Prognostic Factors for the Failure of the Shockwaves in the Treatment of TendinopathyNotarnicola Angela, Bari, Italy 7

12:20 – 12:30 The Significance of Inflammatory Tendon Hypervascularization for the Treatment Results With ESWT: Are the Actual Recommendations Still Valid?Gleitz Markus, Luxembourg, Luxembourg

8

12:30 – 12:40 Local Blockage Decrease the Effect of Radial Extracorporeal Shockwaves Therapy for Achilles TendinitisLiu Yayun, Beijing, China

9

12:40 – 12:50 Extracorporeal Shock Waves Trigger Tenogenic Differentiation of Human Adipose Derived Stem CellsCatalano Maria Graziella, Turin, Italy

10

12:50 – 13:00 High-Energetic Focused Extracorporeal Shockwave (ESWT) Reduces Pain Levels in the Nodular State of Dupuytren’s Disease (DupuyShock)Knobloch Karsten, Hannover, Germany

11

13:00 – 13:10 Soft Focused Extracorporeal Shockwaves Increase the Expression of Tendon-Specific Markers and the Release of Anti-Inflammatory Cytokines in an Adherent Culture Model of Primary Human Tendon CellsVigano Marco, Milan, Italy

12

13:10 – 13:20 Shockwave Exposure Improves Tendon RegenerationVisco Vincenzo, Rome, Italy 13



15


16

Session time


15:00 – 15:15 KEYNOTE LECTURE: Basic Science of Bone Turnover In Fracture Healing & MetabolismPietrogrande Luca, Milan, Italy

15:15 – 15:30 KEYNOTE LECTURE: Biological Strategies for Improving Bone RepairSansone Valerio, Milan, Italy

15:30 – 15:45 ISMST RESEARCH AWARD LECTUREWnt Signaling in Shock Waves Induced Bone RegenerationMarianne Koolen, Utrecht, Netherlands

15:45 – 15:55 Shockwave Treatment for Deep Orthopaedic InfectionsCoombs Richard, London, England 14

15:55 – 16:05 Intractable Bone Marrow Edema Syndrome of the Hip: High Energy Extracorporeal Shockwave is an Amazing TechnologySun Wie, Beijing, China

15



16:45 – 18:05 Bone II Session 4

Chair: D'Agostino M. Cristina – Italy Leal Carlos – Colombia Wang Ching Jen – Taiwan

Session time


16:45 – 16:55 Results of Piezoelectric Shockwave Therapy for the Treatment of Bone Non – Unions: Four Years ExperienceSermyazhko Galina, Tula, Russia

16

16:55 – 17:05 Extracorporal Shockwaves in the Treatment of High Energy Lower Limbs Long bone Non UnionSandoval Carlos, Santiago, Chile

17

17:05 – 17:15 “Fractures at Risk” – Which Patient Will Benefit of Shockwave Therapy (ESWT)?Bäetje Frank, Hannover, Germany 18

17:15 – 17:30 KEYNOTE LECTURE: Nonunion: Evolution of Shock Wave Therapy on the Basis of the Mechanisms of Action and the Available EquipmentRusso Sergio, Naples, Italy

17:30 – 17:45 KEYNOTE LECTURE: ESWT for Non – Union Fractures – Evidence Based MedicineSchaden Wolfgang, Vienna, Austria


18:05 Adjourn

18:30 ISMST Annual General Meeting

20:30 ISMST WELCOME PARTY“Memo Restaurant” (Milan) www.memorestaurant.com

15:00 – 16:25 Bone I Session 3

Chair: Gigliotti Sergio – Italy Russo Sergio – Italy Schaden Wolfgang – Austria

08:00 – 10:15 ESWT Basic Research II Session 5

Chair: Frairia Roberto – Italy Holfeld Johannes – Austria Mc Clure Scott – USA

Session time


08:00 – 08:15 KEYNOTE LECTURE: Shockwave Medicine … A Revolution Towards the FutureWang Ching-Jen, Kaohsiung, Taiwan

08:15 – 08:25 Serum Proteomic Analysis of Extracorporeal Shockwave Therapy Enhanced Diabetic Wound Healing in a STZ-Induced Diabetes ModelKuo Yur-Ren, Kaohsiung, Taiwan

19

08:25 – 08:35 Comparison the Effects of Extracorporeal Shockwave Therapy and Hyperbaric Oxygen Enhanced Diabetic Wound Healing in a Rat Model of STZ-Induced DiabetesKuo Yur-Ren, Kaohsiung, Taiwan

20

08:35 – 08:45 Functional and Molecular Characteristic of Underactive Bladder Induced by Lumbar Canal Stenosis in Rats and Effects of Low Energy Shockwave TherapyWang Hung-Jen, Kaohsiung, Taiwan

21

08:45 – 08:55 Umbilical Cord Mesenchymal Stem Cell Therapy Enhanced Islet Cells RepairHsiao Chang-Chun, Kaohsiung, Taiwan 22

08:55 – 09:05 Benefit of Combined Extracorporeal ShockWave and Bone Marrow-Derived Endothelial Progenitor Cells in Protection Against Critical Limb Ischemia in RatsSheu Jiunn-Jye, Kaohsiung, Taiwan

23

09:05 – 09:15 Shockwave Triggers Cultured Mesenhcymal Stem Cell Proliferation via Activating mTOR-FAK Signaling Axis Lee Fan-Yen Kaohsiung, Taiwan

24

09:15 – 09:25 Extracorporeal Shockwave Therapy Reverses Ischemia-Related Left Ventricular Dysfunction and Remodeling: Molecular-Cellular and Functional AssessmentSheu Jiunn-Jye, Kaohsiung, Taiwan

25

09:25 – 09:35 Extracorporeal Shock Wave Effectively Attenuate Brain Infarct Size Improve Neurological Function in Rat ModelYuen Chun-Man, Kaohsiung, Taiwan

26

09:35 – 09:45 Combined Therapy with Extracorporeal Shockwave and Bone Marrow Derived Mesenchymal Stem Cell Alleviates Left Ventricular Dysfunction and Remodeling through Inhibiting Inflammatory Stimuli & Enhancing Angiogenesis in a Swine Acute Myocardial Infarction ModelSheu Jiunn-Jye, Kaohsiung, Taiwan

27

09:45 – 09:55 Extracorporeal Shockwave Therapy Enhanced Diabetic Wound Healing is Associated with Modulation of wnt/b-Catenin ExpressionYang Kuender, Chang Hua, Taiwan

28



07:30 – 18:00 Registration & Industrial exhibition

17



18

Session time


10:35 – 10:50 KEYNOTE LECTURE: Tendinopathies – What's NewMaffulli Nicola, London, England

10:50 – 11:00 Shockwave Therapy for Patellar Tendinopathy in Patients with Total Knee ArthroplastiesLeal Carlos, Bogota, Colombia

29

11:00 – 11:10 Shockwave Therapy in Pes Anserinus Tendinopathies: Report of 239 CasesAudain Rosanna C., Valencia, Venezuela 30

11:10 – 11:20 Effect of Extracorporeal Shockwave Therapy on Variable Foot & Ankle Musculoskeletal Diseases Young Kiwon, Seoul, Korea

31

11:20 – 11:30 The Effectiveness of Extracorporeal Shockwave Therapy in Patients with Plantar FaciitisKöse Tugçe, Denizli, Turkey

32

11:30 – 11:40 Combined Focused and Radial Shockwave Therapy in the treatment of Plantar FasciitisVerratti Gabrielle, Caracas, Venezuela 33

11:40 – 11:50 Lateral Epicondilopathy and ESW. B-Mode Ultrasound, Power Doppler and Pulse Doppler in the Evolution and Prognosis in Tendinopathy. Alarcon Garcia Juan Maria, Madrid, Spain

34

11:50 – 12:00 Effectiveness of Shockwave Treatment Compared With Eccentric Exercises and Mobilization for Chronic Lateral Epicondylitis of the Elbow. A Prospective, Randomized, Blinded, Multicentric StudyAranzabal Jose Ramon, San Sebastian, Spain

35

12:00 – 12:10 Piezoelectric Shockwave Therapy in Management Lateral Epicondylitis of the ElbowBalabel Ayman Elwey, Ahmadi, Kuwait 36

12:20 – 12:30 Radial Shockwave Therapy and High Frequency Laser Combined Treatment in Elbow TendinopathiesLeal Carlos, Bogota, Colombia

37



10:35 – 12:50 Tendon II Session 6

Chair: Vulpiani Mariachiara – Italy Furia John – USA Buselli Paolo – Italy

14:00 – 16:00 Tendon III Session 7

Chair: Amelio Ernesto – Italy Rompe Jan – Germany Moya Daniel – Argentina

Session time


14:00 – 14:15 KEYNOTE LECTURE: Rotator Cuff Lesion Surgery: A Long History Towards a Lesser Invasive TechniqueRandelli Pietro, Milan, Italy

14:15 – 14:30 KEYNOTE LECTURE: Shoulder Tendinopathies – “The Biological Surgery”?Castagna Alessandro, Milan, Italy

14:30 – 14:40 Extracorporeal Shockwave Therapy in Calcific Tendinosis of the Rotator Cuff: Comparison of Radial and Focal TreatmentSerrano Edson, Lima, Peru

38

14:40 – 14:50 Combination of Shockwave Therapy with Exercise in Shoulder Tendinopathy: Preliminary Results on Percieved Functional OutcomeRuggiero Gianluca, Milan, Italy

39

14:50 – 15:00 The Effects of Radial Extracorporeal Shockwave Therapy on Function, Range of Motion, Strength and Pain in Patients with Chronic Rotator Cuff TendinosisSanzo Paolo, Thunder Bay, Canada

40

15:00 – 15:10 Dynamic Myofascial Treatment and ESWTNedelka Jiri, Prague, Chezch Rep 41

15:10 – 15:20 Radial Extracorporeal Shockwave Therapy in FibromyalgiaRamon Silvia, Barcelona, Spain 42

15:20 – 15:30 How to Increase Good Clinical Practice in Shockwave Therapy: The Importance of a Correct Communication Between ESWT Specialist and General PractitionerOttone Maria Cristina, Milan, Italy

43

15:30 – 15:40 The Smartphone APP: A Tool for Enhancing Patient EducationFuria John, Lewisburg, USA 44


16:00 – 16:15 Coffee break

16:30 – 18:00 ISMST Industrial Meeting (The location will be announced at the registration desk of the congress)

19


16:15 – 17:15 Urology Session 8

Chairmen: Giusti Guido – Italy Coombs Richard – UK Schaden Wolfgang – Austria

Session time


16:15 – 16:30 KEYNOTE LECTURE: Urological Lithotripsy: From the Origin to the Present DayGiusti Guido, Milan, Italy

16:30 – 16:40 Extracorporeal Shock Wave Therapy Inhibits Cyclophosphamide-Induced Rat Acute Interstitial CystitisChen Yan-Ta, Kaohsiung, Taiwan

45

16:40 – 16:50 Functional and Molecular Characteristic of Cyclophosphamide Induced Cystitis in Rats and Effects of Low Energy Shock Wave TherapyChuang Yao-Chi, Kaohsiung, Taiwan

46

16:50 – 17:00 Does Extracorporeal Shockwave Therapy (ESWT) have an Effect on Erectile Dysfunction – Preliminary ResultsLyngdorf Peter, Gentofte, Denmark

47


17:15 – 18:15 Cartilage Session 9

Chair: Romeo Pietro – Italy Coombs Richard – UK Kuderna Hans – Austria

Session time


17:15 – 17:25 Extracorporeal Shockwave Therapy for Osteoporotic Osteoarthritis of the Knee in Rats: An Experiment in AnimalsWang Ching-Jen, Kaohsiung, Taiwan

48

17:25 – 17:35 Efficacy of Extracorporeal Shockwave Therapy for Knee Osteoarthritis: A Randomized Controlled TrialXing Gengyan, Beijing, China

49

17:35 – 17:45 Extracorporeal Shockwave Therapy and Alendronate Demonstrate Equal Protective Effects in Osteoarthritic KneesShan-Ling Hsu, Kaohsiung, Taiwan

50

17:45 – 17:55 ESWT of Chronic Osteochondral Lesions of the TalusXing Gengyan, Beijing, China 51

17:55 –18:15 Discussion

18:15 Adjourn

20:30 ISMST PRESIDENTIAL DINNERMuseo Scienza e Tecnica Leonardo da Vinci“Column Hall”


20


08:30 – 10:05 Neurology Session 10

Chair: Buselli Paolo – Italy Raveendran Kandiah – Malaysia Thiele Richard – Germany

Session time


08:30 – 08:45 KEYNOTE LECTURE: Focused Low Energy Shockwaves in the Neurological Rehabilitation. An OverviewLohse-Busch Henning, Bad Krozingen, Germany

08:45 – 08:55 Medical Shockwaves a Treatment Option for Complex and Neuropathic Pain Syndromes? A Compilation of Case ReportsCraig Kenneth, Auckland, New Zealand

52

08:55 – 09:05 Focused Extracorporeal Shockwaves Improve Pareses in 8 Cases of Spinal Cord Injury and 3 Cases of MyelomeningoceleLohse-Busch Henning, Bad Krozingen, Germany

53

09:05 – 09:15 The Activating Effect of ESWT on Schwann Cells in Vitro and in VivoHercher David, Vienna, Austria 54

09:15 – 09:25 Symptomatic Treatment of Unresponsive Wakefulness Syndrome with Transcranially Focused Extracorporeal Shockwaves (TESWT)Lohse-Busch Henning, Bad Krozingen, Germany

55

09:25 – 09:35 Shockwaves Induce Postnatal Vasculogenesis in Infarcted Myocardium by Recruitment of Bone Marrow Derived Endothelial ProgenitorsHolfeld Johannes, Innsbruck, Austria

56

09:35 – 09:45 Focused Low-Energy Extracorporeal Shockwaves with Distally Symmetric Polyneuropathy (DSPNP). A Pilot StudyLohse-Busch Henning, Bad Krozingen, Germany

57



08:00 – 14:00 Registration & Industrial exhibition

10:25 – 11:40 Skin I Session 11

Chair: Ligresti Claudio – Italy Knobloch Karnsten – Germany Saggini Raoul – Italy

Session time


10:25 – 10:40 KEYNOTE LECTURE: State of the Art in Wound Care Regenerative TechnologiesLigresti Claudio, Rome, Italy

10:40 – 10:50 Shockwave Treatment Enhances Proliferation and Wound Healing via Purinergic Signaling Linked Erk1/2 PathwaysWeihs Anna, Vienna, Austria

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11:00 – 11:10 Defocused ESWT as Strategical Tool in Vulnology: Our ExperienceAbati Elena Maria, Milan, Italy 59

11:10 – 11:20 The Role of ESWT and Manual Lymphatic Drainage in the Treatment of Grade II Chronic UlcersSaggini Raoul, Vienna, Austria

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11:40 – 13:10 Skin II Session 12

Chair: Klinger Marco – Italy Gleitz Markus – Luxembourg D'Agostino M. Cristina – Italy

Session time


11:40 – 11:50 Extracorporaeal Shockwave Therapy in Chronic Ulcers Treatment: Experience in a Vulnologic CenterChiarenza Stefania, Monza, Italy

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11:50 – 12:00 Influence of Treatment Frequency on Healing Outcome in Subacute and Chronic WoundsMittermayr Rainer, Vienna, Austria 62

12:00 – 12:10 Regenerative Model With ESWT in Atrophic and Retracting ScarsSaggini Raoul, Chieti, Italy 63

12:10 – 12:20 Shockwave Therapy as a Part of the Reconstructive Clockwork – a Conceptual WorkKnobloch Karsten, Hannover, Germany 64

12:20 – 12:35 KEYNOTE LECTURE: The Diabetic Foot Triage: Integrated Surgical ApproachCaravaggi Carlo, Bergamo, Italy

12:35 – 12:50 KEYNOTE LECTURE: Shockwave Medicine and Leprosy: The Ultimate Challenge for Skin Regeneration by MechanotransductionLeal Carlos, Bogota, Colombia


13:10 – 14:00 CLOSING CEREMONY

AWARD CEREMONY Markus Gleitz

CLOSING REMARKSM. Cristina D'Agostino

ISMST MENDOZA 2015Daniel Moya


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Session 2 – Tendon I

Keynote speakers

Prof. Manuel Branes (Chile) Faculty of Sciences – University of Chile“Mechano Trasduction: A Lesson From Ancient Times”[email protected]

Prof. Roberto Frairia (Italy)Department of Medical Sciences – University of Turin, Italy“From Mechanotransduction to Shockwave Biology”[email protected]

Dr. Holfeld Johannes Department of Cardiac Surgery – Innsbruck Medical University, Austria“New Findings in Experimental Shockwave Science – Summary of the Basic Research Meeting in Frankfurt”[email protected]

Prof. Massimo Locati (Italy) Laboratory of Leukocyte Biology – University of Milan Humanitas Clinical and Research Center, Milan“Macrophages at the Cross-Road Between Inflammation and Regeneration” [email protected]

Session 1 – ESWT Basic Research I

Prof. Piero Volpi (Italy) Knee Surgery and Sport Traumatology Unit, Humanitas Research Hospital – Milan (Italy)“New Biological Strategies for Tendinopathies”[email protected]

Prof. Hans Van Schie (The Netherland) Department of Equine Sciences (DES) – Utrecht University“UTC – A Novel Tool for Management of Tendinopathy”[email protected]

Dr. Marianne Koolen (The Netherlands) Orthopedics Department – UMC Utrecht “Wnt Signaling in Shock Waves Induced Bone Regeneration”

Prof. Luca Pietrogrande (Italy)Orthopedic and Traumatology Department, S. Paolo Hospital – University of Milan“Basic Science of Bone Turnover in Fracture Healing & Metabolism”[email protected]

Prof. Valerio Sansone (Italy)Orthopaedic Department, Istituto Ortopedico Galeazzi – University of Milan“Biological Strategies for Improving Bone Repair” [email protected]

Session 3 – Bone I

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Dr. Sergio Russo (Italy)Faculty of Medicine – University Federico II, Naples“Nonunion: Evolution of Shock Wave Therapy on the Basis of the Mechanisms of Action and the Available Equipment” [email protected]

Dr. Wolfgang Schaden (Austria)AUVA Trauma Centre Meidling, Austria“ESWT for Non-Union Fractures – Evidence Based Medicine”[email protected]

Session 4 – Bone II

Prof. Wang Ching-JenChang Gung University College of Medicine – Kaohsiung Chang Gung Memorial Hospital, Taiwan“Shockwave Medicine ….. A Revolution Towards the Future” [email protected]

Session 5 – ESWT Basic Research II

Session 6 – Tendon II

Prof. Nicola Maffulli (Italy, UK) University of Salerno School of Medicine and Surgery, Salerno, ItalyBarts and The London School of Medicine, Queen Mary University of London, EnglandPresident and Founder of the Guest Societes ISMuLT and InMuLTS“Tendinopathies – What’s New”[email protected]

Prof. Alessandro Castagna (Italy)Shoulder and Elbow Orthopedic Unit at Humanitas Research Hospital – Milan (Italy)President of the SECEC – Société Europèenne de Chirurgie de l'Epaule et du Coude" “Shoulder Tendinopathies – “The Biological Surgery”[email protected]

Prof. Pietro Randelli (Italy)Shoulder and Miniinvasive Surgery Unit, San Donato Research Hospital – University of MilanSecond Vice President of the Guest Society SIGASCOT“Rotator Cuff Lesion Surgery: A Long History Towards a Lesser Invasive Technique”[email protected]

Session 7 – Tendon III

Dr. Giudo Giusti (Humanitas, Italy)“Stone Center” of Urologic Unit – Humanitas Research Hospital, Milan, Italy“Urological Lithotripsy: From the Origin to the Present Day”[email protected]

Session 8 – Urology

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Dr. Lohse – Busch Henning (Germany)Rheintalklinik Bad Krozingen“Focused Low Energy Shockwaves in the Neurological Rehabilitation. An Overview”

Session 10 – Neurology

Session 11 – Skin

Prof. Claudio Ligresti (Italy)Delegate for International Relationships of the Guest Society CO.R.TE and IAWC – Italian Academy of Wound Care“State of the Art in Wound Care Regenerative Strategies”[email protected]

Dr. Carlo Caravaggi (Italy) Delegate of AIUC) Diabetic Foot Center, Istituto Clinico Città Studi of Milan and Humanitas Gavazzeni in Bergamo (Italy)“The “Diabetic Foot Triage”: an Integrated Surgical Approach”[email protected]

Prof. Carlos Leal (Colombia)Fenway Medical, Colombia “Shockwave Medicine and Leprosy: The Ultimate Challenge for Skin Regeneration by Mechanotransduction”[email protected]

Session 12 – Skin II

Social events and programs

We are glad to offer you a wide range of social events and programs

ISMST Welcome Party

On Thursday, June 26, all participants are cordially invited to participate to ISMST Welcome Party which will be celebrated at the amazing Memo Restaurant Music Club in Milan.

Memo is a typical example of building reconversion: it was an old cinema, built at the end of the 50s and now a restaurant. The architect Memo Colucci decided to bring the cinema back to its old splendor: the interior is inspired to a dreamer travel experience, walking trough ancient objects and overseas music atmosphere. The stage is the soul of the club; it is the origin of the music and represents the reason why people gather. Here, a wide range of artists is offered (jazz, pop, blues, singer-songwriter)

The main-character of the Memo is obviously the menu: it is possible to taste typical Italian food, from meat, to desserts, to appetizer such as pizza and focaccia bread.

Congress participants with their accompanying person(s) are cordially welcome to join this social evening at a fee of € 40 per person.

ISMST Welcome Party is not included into congress fee.

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Presidential Dinner

On Friday, June 28, the official ISMST Presidential Dinner will take place in a picturesque setting into one of the most impressive location in downtown Milano: National Museum of Science and Technology.

The Museum houses the largest world collection of models interpreting Leonardo’s drawings. Created in the 1950s, it is the first to have dealt systematically with Leonardo da Vinci’s sci-entific-technical studies. Today, these models represent an exceptional tool for the study and dissemination of Leonardo’s technical-scientific work, as well as having a unique educational value. A selection of models is permanently exhibited in the Leonardo Gallery. The Museum works on developing interpretation tools related to this important collection: interactive workshops, multimedia, 3D animations to better understand the functioning of the machines, games, thematic studies on the website, and a recent free Italian and English iPhone App “LeonardoAround” dedicated to the exploration of Leonardo’s work and legacy in Milan.

With exhibitions, workshops and seminars, the Museum engages in the worldwide dissemina-tion of knowledge on Leonardo da Vinci’s work. Among recent international collaborations are: the exhibition "Léonard de Vinci, projets, dessins, machines" by Universcience in collabo-ration with the Museum and the Deutsches Museum, in Paris until August 2013; the displays "Leonardo da Vinci and the Ideal City" at the Urban Footprint Pavilion Expo 2010 Shanghai in China; "Leonardo da Vinci. Nature, art & science" at the Incheon Triennial in South Korea in 2009; “Leonardo da Vinci workshop caravan" in Japan in 2009.

Sala Colonne (Columns Hall), where the event will take place, is the antique library of the Olivetan monastery; it is a fascinating space that overlooks two beautiful Renaissance cloisters. The elegant architecture, marked by a succession of arches and columns, makes this room ideal for hosting exclusive events. Founded to host the monks of the Olivetan order, the cen-tral body of the Museum was built in the early 16th century as a monastery.

Education is one of the main purposes of a museum and it has been a fundamental objective at the National Museum of Science and Technology Leonardo Da Vinci since it was founded. Italy’s largest technical-scientific Museum is also a unique resource for everyone. The Educa-tion Department staff works with the aim of making the Museum a place for discovery, expe-rience, understanding and inspiration accessible to all.

The Presidential dinner is included into congress fee. Congress participants are also invited to bring accompanying guests. The fee is € 60 per accompanying guest.

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Serravalle Outlet Village

Thursday, June 26

Travel from Milan to Serravalle Outlet Scrivia by private bus from Hotel Quark Fashion Passport, which provides a further reduction of 10% in participating stores to all members of the group.

FEE: € 30,50 per head for a minimum of 35 guests

The fare includes the round trip in a private bus and the Fashion passport.

Guided visit to Como

Friday, June 27Bus & Boat itinerary

10:00 am Meeting with the guide, bus to Villa Carlotta

11:00 am Visit to the Villa/Museum and its magnificent botanical garden

12:25 pm Shuttle boat to Bellagio

12:40 pm Free lunch

02:00 pm Visit to the village, with its typical stairways and free time for shopping

03:23 pm Hydrofoil to Como

04:07 pm Arrival in Como, visit of the town centre

05:15 pm End of the tour

FEE: € 80.00 per head for a minimum of 35 guests

The price includes the English-speaking guide, tickets to museums and bus and boats transfers.

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Guided visit in Milano

Saturday, June 28

Departure from Hotel Ata Quark at 10 am, with the tram number 15 you will reach Piazza Fontana. Visit of the Duomo and its Terraces, visit of the Theatre Museum at La Scala and a stroll through Piazza Cordusio, via Verdi, Piazza Cairoli/Foro Buonaparte to the Sforzesco Castle where you can visit the courtyards.

Visit the beautiful Pinacoteca Ambrosiana (where you can admire the masterpieces of Caravaggio, Raphael, Titian and Leonardo da Vinci) and the exhibition of the Atlantic Code of Leonardo da Vinci at the library.

FEE: € 80,00 per head for a minimum of 35 guests

The fare includes the English-speaking guide and museum tickets.

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