16corneal degenerations
TRANSCRIPT
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CORNEAL DEGENERATIONS
1. Age-relatedArcus senilis
Vogt wite li!"al girdle
#. Li$id %erato$at&
Crocodile sagreenCornea guttata
'ri!ar&
Secondar&
(. )and %erato$at&
*. S$eroidal degeneration
+. Sal,!ann nodular degeneration
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Arcus senilisInnocuous and etre!el& co!!on in elderl&
Occasionall& associated wit &$erli$o$roteinae!ia
)ilateral circu!/erential "ands
o/ li$id de$osits Di//use central and sar$
$eri$eral "order
'eri$eral "order se$arated
/ro! li!"us "& clear ,one Clear ,one !a& "e tinned
0 senile /urrow
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Vogt wite li!"al girdle Innocuous and 2er& co!!on in elderl& )ilateral
3ite crescentic line along nasal and te!$oralli!"us
T&$e 1 - se$arated /ro! li!"us "& clear ,oneT&$e # - not se$arated "& clear ,one
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Crocodile sagreen4nco!!on and innocuous 4suall& "ilateral
'ol&gonal stro!al o$acities se$arated "&
clear s$ace5ost /re6uentl& in2ol2e anterior stro!a 0anterior crocodile sagreenOccasionall& in2ol2e $osterior stro!a
0$osterior crocodile sagreen
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Cornea guttataCo!!on "ilateral and usuall& innocuousRarel& $rogression to 7ucs d&stro$&
Tin& dar% s$ots on central endoteliu!
Si!ilar $eri$eral lesions are 8assell-8enle "odies
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Li$id %erato$at&
4suall& unilateral stro!al de$osits witout 2asculari,ation
Rare occurs s$ontaneousl& ina2ascular cornea
4nilateral stro!al de$osits wit2asculari,ation
Co!!on secondar& to $re2iousdisci/or! %eratitis
Treat!ent- coagulation o/ /eeder 2essels and9or %erato$last&
Treat!ent- %erato$last& i/ se2ere
'ri!ar& Secondar&
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)and %erato$at&
Inter$al$e"ral li!"al o$aci/ication
Co!!on unilateral or "ilateral de$ending on cause
Su"e$itelial calci/ication
Central s$read o/ calci/ication
S!all oles witin calci/ied areaSe$arated "& clear ,one
'rogression
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Causes o/ )and :erato$at&
1. Ocular 0co!!on
Silicone oil in anterior ca!"er
Increased seru! calciu! and $os$orus
Cronic iridoc&clitis $articularl& in cildren
8&$eruricae!ia
Associated wit $tisis "ul"i
(. 8ereditar& 0rare
Cronic renal /ailure
7a!ilial "and %erato$at&8ereditar& ict&osis
#. 5eta"olic 0rare
*. Age-related 0unco!!on
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Re!o2al o/ corneal e$iteliu! A$$lication o/ sodiu! 2ersenate
Celation o/ "and %erato$at&
S id l d i
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S$eroidal degeneration
Treat!ent
Central s$read coalescence and
o$aci/ication
Ad2anced lesions "eco!e
nodular and ele2ated
Rare t&$icall& a//ects outdoor wor%ers
Starts wit $eri$eral inter$al$e"ral s!all a!"er-coloured granules in su$er/icial stro!a
De"ride!ent or su$er/icial %eratoto!& i/ !ild
:erato$last& i/ se2ere
'rogression
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Sal,!ann nodular degeneration4nco!!on unilateral or "ilateralSecondar& to cronic %eratitis
Discrete su$er/icial stro!al o$acitiesand nodules
)ase o/ nodule !a& "e surrounded "&iron de$osits
Treat!ent- si!ilar to s$eroid degeneration