16 cox cloudcomputing
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Nancy J. Cox, Ph.D.
The University of Chicago
http://genemed.uchospitals.edu
Cloud Computing forLarge-Scale Sequencing
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G C A C G G T T
T C C C A G T
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G T T
A G C
C G T A T T
G C A C G G T T
T T A A A C T T
C C C T
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C
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Challenges
IRB
HIPAA
Insurance,
laws
$1000Genome
$100,000
GenomeAnalysis
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The sky wont fall;
we used to worryabout how wewould deal withthe deluge of datafrom GWAS
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What is Cloud Computing?
Anything and everything that is outthere not on your desktop or laptop
Outsourcing
IT support
Hardware
Software
A new way of doing business Scale to what you need when you need it
Dont own what you cannot use completelyefficiently
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Keys to Cloud Computing
A revolution in the virtualization ofcomputing architecture Security and connectivity can be defined
at the level of the processor Expanded and contracted as needed
Redundant and abundant (cheap) datastorage
Computational resources to processdata are local to the data
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Public Vs. Private Clouds
Private clouds can be developed tomeet any level of required security HIPAA compliant clouds with EMR data
dbGaP-level security for omics researchdata
Amazon, Google, DropBox, etc
Extremely cost effective and very reliablefor large-scale but short-term usage
Amazon hosting 1000 Genomes (and otherlarge-scale omics) data for computations
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Get Your Amazon GrantApplication in Soon!
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Public Clouds Scientific Commons
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HIPAACLO
UD
Public Clouds Scientific Commons
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HIPAACLO
UD
Public Clouds Scientific Commons
CDW
DM
AUX
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HIPAACLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
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HIPAACLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
CLIA Lab
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HIPAACLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
My localdropbox
CLIA Lab
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HIPAACLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
My localdropbox
CLIA Lab
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HIPAACLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
My localdropbox
CLIA Lab
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HIPAA
CLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
cluster
My localdropbox
CLIA Lab
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HIPAA
CLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
cluster
My localdropbox
CLIA Lab
ENCODE
1KG
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Colleagues & Collaborators
Bob Grossman Ian Foster Kevin White
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HIPAA
CLO
UD
Public Clouds Scientific Commons
CDW
DM
-omics
results
AUX
Sequencing Core
-omicsdata
My localdropbox
CLIA Lab