13 partnerships for ultra-high sensitivity lc-msms gary valaskovic - new objective
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5 minutes of fameTRANSCRIPT
Partnerships for Ultra-high Sensitivity LC-MS/MS
CPSA 2012 Vendor Session, Langhorne PA
Gary ValaskovicNew Objective Inc.
Skilled & Dedicated Staff in a Responsive Environment
Production Engineering
Customer & Technical Support
You!
Partnership for Performance
Customer Partnerships with NOI•PicoChip Development
• Nate Yates, University of Pittsburgh• Neil Kelleher, Northwestern Univesristy• John Yates, Scripps Research Institute• Steve Gygi, Harvard University
•Workshops on Peptide Quantitation• Nalini Sadagopan, Agilent Technologies• Mike MacCoss, University of Washington
•Microspray for Quantitation• Shane Needham, Alturas Analytics, Inc.• Brad Ackerman, Eli Lilly & Co.
•Ultra-nano Separations for Biomarker Studies• Barry Karger, Northeastern University
•Nanospray Source Development • Jarrod Marto, Dana Farber Cancer Institute• Susan Wientraub, UT Health Science
•Heated Column Nanospray
• Sue Abbatiello, Broad Institute• Ken Lewis, OpAns• Neil Kelleher, Northwestern University
•Ultra-low Flow Pump• Jing-Tao Wu, Millenium Pharmaceuticals
•Segmented Flow Nanospray• Bob Kennedy, University Michigan
•Intact Protein Biomarkers• Ying Ge, University of Wisconsion
Corporate Partnerships & Collaborations
Partnership for Performance
When Partnership becomes the future:PicoChip™ system
“We need this to be easy to use . . . .
. . . but we don’t want to give up any performance!”
Nathan YatesUniversity of Pittsburgh
Partnership for Performance
PicoChip™ – Easy to use, high performance nanospray
Complex Specialized expertise
SimpleUniversal productivity
Mount source, connect column to HPLC
Activate column Collect data
Partnership for Performance
“I have a dream – To have a mass spec. based plate reader”
Jing-Tao Wu, Ph.D.
CPSA 2005 Closing Lecture, Princeton NJ
When Partnership becomes the future:
“Chromatography is analog.We need to digitize chromatography. . . “
Mike S. Lee(Circa 1998)
Partnership for Performance
When Partnership becomes the future:Segmented Flow Electrospray
Partnership for Performance
Bob KennedyUniversity Michigan
When Partnership becomes the future:Segmented Flow Electrospray
Sample 4
Sample 5
Sample 6
Sample 1
Sample 2
Sample 3
Pump
ESINano Spray
m/z m/z
Mass Spectrometer
Sample 1
Sample 2
Sample 3
Data Out
Sample 4
Sample 5
Sample 6
Blanks
When Partnership becomes the future:Segmented Flow Electrospray
Sample 4
Sample 5
Sample 6
Sample 1
Sample 2
Sample 3
Pump
ESINano Spray
m/z m/z
Mass Spectrometer
Sample 1
Sample 2
Sample 3
Data Out
Sample 4
Sample 5
Sample 6
Blanks
When Partnership becomes the future:Segmented Flow Electrospray
Sample 4
Sample 5
Sample 6
Sample 1
Sample 2
Sample 3
Pump
ESINano Spray
m/z m/z
Mass Spectrometer
Sample 1
Sample 2
Sample 3
Data Out
Sample 4
Sample 5
Sample 6
Blanks
When Partnership becomes the future:Segmented Flow Electrospray
Sample 4
Sample 5
Sample 6
Sample 1
Sample 2
Sample 3
Pump
ESINano Spray
m/z m/z
Mass Spectrometer
Sample 1
Sample 2
Sample 3
Data Out
Sample 4
Sample 5
Sample 6
Blanks
Thank You!
Partnership for Performance