11 april, 2003 pmril autotuning interventional coils for imaging ross venook, greig scott, garry...

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11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

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Page 1: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Autotuning Interventional Coils for Imaging

Ross Venook, Greig Scott,

Garry Gold & Bob Hu

Page 2: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Motivation for Automatic Tuning: Clinical Realities

• Interventional applications = uncontrolled variables– Flexible coils are clinically desirable

– Stuff is inhomogeneous and uncooperative inside the body (even an unconscious subject has moving things under the surface)

• Specific interventional applications– ‘deployable’ RF coil

– Range of motion studies

Page 3: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Motivation for Automatic Tuning: Technical Consequences

• RF coils are basically inductive loops with a tuning capacitance– Changing the shape or size of the loop changes the

inductance (and hence its tuned peak), but manual adjustment of capacitors is slow

• Closer coupling between the coil and the load means increased coil dynamics

• SNR depends on coil tuning (matching)

Goal: Create an automatic tuning device to quickly and easily optimize coil SNR

Page 4: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Agenda

• Motivation

• Background– Autotuning method– Electronics development– Old results

• Autotuning with Signa

• Theoretical SNR analysis

• Future work

Page 5: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Background I: ‘Autotuning’

• Autotuning is the process by which a tuned coil’s center frequency is adjusted without manual effort (push-of-a-button)

• Many methods/topologies exist which can accomplish the task of tuning (and matching) a resonant circuit– Probe topology important

– Tuning topology important

Page 6: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Background II: Autotuning Method

• Tuned elements have a complex impedance• ‘Resonance frequency’ is defined by zero

imaginary impedance

50 55 60 65 70 750

10

20

30

40

50

60

Frequency [MHz]

Res

ista

nce

[Ohm

s]

50 55 60 65 70 75-30

-20

-10

0

10

20

30

Frequency [MHz]

Rea

ctan

ce [O

hms]

Page 7: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

At 63.9MHz

0

10

20

30

40

50

60R

esis

tanc

e [O

hms]

-20

-10

0

10

20

30

Rea

cta

nce

[Ohm

s]

50 55 60 65 70 75

10

20

30

40

50

60

Frequency [MHz]

Res

ista

nce

[Ohm

s]

50 55 60 65 70 75

-20

-10

0

10

20

30

Frequency [MHz]

Rea

cta

nce

[Ohm

s]

10

20

30

40

50

60

Res

ista

nce

[Ohm

s]

-20

-10

0

10

20

30

Rea

cta

nce

[Ohm

s]

0

0

Page 8: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Electronics:Varactor-tunable RF Coil

75nH

22 or 68pFVaractor

Q spoil SignalPort<360nH

C

9 V

20K 20K150pF

10K

C

DC Tuning Bias

Signal

Flex CoilDC Tuning Bias

Page 9: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Electronics:Reactance Detection

• Phase comparator outputs a DC voltage that is a function of probe reactance

-600-400-200

0200400600

55 57 59 61 63 65 67 69

Frequency (MHz)

DC

out

put (

mV

)

Page 10: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Electronics: Microcontroller

• Atmel 90S8515 microcontroller operates the state machine via SPI (serial peripheral interface)

FrequencySynthesizer

Micro-Controller

PhaseDetector

Scanner Pre-amp

Tune/ReceiveSwitch

VaractorTuningVoltage

RF Coil

Page 11: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Retuned

Retuned

Frequency (MHz)

Res

ista

nce

(Ω)

61 62 63 64 65 66 67

10

20

30

40

50

60

DetunedDetuned

Punchline

Page 12: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Agenda• Motivation• Background• Autotuning with Signa

– Initial experiments: RFI, and other problems– Improved autotuner– Initial experiments (for real, this time)– SNR increase observed (!)

• Theoretical SNR analysis• Future work

Page 13: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Initial Images (Problems)

• RF interference artifact caused by switching power supply

• Common-mode

transients affect

microcontroller,

TR switch fails

while imaging

Page 14: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Solution• Replace switching supply and 3V Li battery (very

cool, non-ferrous)…

• …with simple voltage regulators and 9V alkalines (not cool, very ferrous) and….

Page 15: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

…goodness results

• Reliable images with autotuner (Greig at Leipzig)

High peak SNR (>300) ‘No’ RFI, some PE ghosting

Windowed-down Windowed-up

(SPGR, TE/TR = 7.2ms/34ms, 4mm slice, 12x12cm² FOV, 30° flip)

Page 16: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Experimental Setup

Varactor-tunedCoil

Phantom

AutotuningElectronics

cable

GE Signa1.5 T

Status LEDs(not blinking)

Page 17: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Experiment #1The Pepsi Challenge

• Varactor-tuned vs. passively-tuned images Varactor-diode

Passive variablecapacitor

Both images have nominal SNR=326

Page 18: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Experiment #2:Tune-Detune-Retune

Autotune Detune (deform coil) Re-autotune

Page 19: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

SNR Profiles

Noise Box Image Sample

SNR

Page 20: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Typical ResultSN

R

Autotune Detune (deform coil) Re-autotune

Page 21: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Agenda

• Motivation• Background• Autotuning with Signa• Theoretical SNR analysis

– Noise Figure and noise circles– Coil -> preamplifier– Coil -> txn line -> preamplifier– An interesting result

• Future work

Page 22: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Noise Figure

• All practical devices have NF>0dB (F>1)• Convenient and sensible metric• Noise Figure is in dB, Noise Factor is not

10log( )

IN

OUT

SNRF

SNR

NF F

Page 23: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Why We Have Preamplifiers

• Friis Equation

• Preamplifier NF dominates system NF (for moderate G1)

– Worry about preamp NF

F1, G1 F2, G2 FN, GN…SNRIN SNROUT

Fi = Noise Factor of ith stage Gi = Gain of ith stage

321 1

1 1 21

1 11IN NN

OUT nn

SNR F FFF F

SNR G G G G

Page 24: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Preamplifier NF• Depends on impedance match, Ropt set by device

R/Ropt

Noi

se F

igur

e [d

B]

Fmin = 1.05, 1.07, 1, 1.2, 1.5

1

2

3

4

5

6

7

0.1 1 10

Page 25: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Preamplifier NF• Actually, NF is a surface on the complex-Z plane

Im[Z]

Re[Z]

NF

(dB

)

Page 26: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Noise Circles

• Preamplifier NF level sets are circles in the complex impedance plane

• Minimum NF occurs at 50 + j0 Ω for this example

Im[Z

] (Ω

)

Re[Z] (Ω)0 1000

0

-500

500

Preamplifier NF Contours [dB] on Z-plane

Page 27: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Autotuning Trajectory

Im[Z

] (Ω

)

Re[Z] (Ω)0 1000

0

-500

500

Preamplifier NF Contours [dB] on Z-plane

•••

• •

•• •

•••

Page 28: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Lossy Transmission Lines

• Coaxial transmission lines connect the coil to the tuner, and the tuner to the scanner– Impedance transformation changes Z at preamp

– Resistive loss adds noise

• Interventional devices require small-diameter coax– Greater loss (dB/m)

– Imperfect impedance transformation

– Together, these warp the system noise circles and trajectories for a given coil

Page 29: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Lossy Transmission Lines (cont…)

• Evaluate impedance ‘mismatch’ by measuring reflected power from a transition– Perfect match has no reflections

• Statement: ‘lossier cable can improve your match because it lowers the reflected power’

• Hmmm….• Counter: ‘what about SNR? Isn’t the baby being

thrown out with the bathwater??’

Page 30: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Interesting Result

• Indeed, lossy transmission line will always have worse SNR at its output than at its input

• But, if we have a preamplifier waiting for us on the other end, perhaps the impedance transformation can improve system SNR

• Conclusion:– It’s something to watch out for

Noi

se F

igur

e [d

B]

1

2

3

4

5

6

7

0.1 1 10

R/Ropt

Page 31: 11 April, 2003 PMRIL Autotuning Interventional Coils for Imaging Ross Venook, Greig Scott, Garry Gold & Bob Hu

11 April, 2003PMRIL

Future Work

• Loose ends– Controlled analysis of tuning vs. SNR with data

• Theoretical– To tune, or not to tune (and how to decide)

• Clinical– Scan cadaver shoulders

• Practical– 0.5T/21MHz version– Test speed limits

• New directions– Automatic matching (perhaps a successful topology to borrow

from CW-EPR)